Published in Biochemistry on March 06, 1990
Neuroserpin, an axonally secreted serine protease inhibitor. EMBO J (1996) 1.33
Thrombin in inflammation and healing: relevance to rheumatoid arthritis. Ann Rheum Dis (1994) 0.97
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease. EMBO J (1992) 5.05
p-Nitrophenyl-p'-guanidinobenzoate HCl: a new active site titrant for trypsin. Biochem Biophys Res Commun (1967) 4.79
The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J (1989) 4.49
Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160. Nature (1992) 4.16
Molecular cloning of cDNAs encoding two isoforms of the catalytic subunit of protein phosphatase 2A. Biochemistry (1987) 3.31
Evidence for N- and C-terminal processing of a plant defense-related enzyme: Primary structure of tobacco prepro-beta-1,3-glucanase. Proc Natl Acad Sci U S A (1988) 2.86
Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidinobenzoate esters. Titration of the enzymes. Biochemistry (1969) 2.61
Selective chemical modification of proteins. Physiol Rev (1970) 2.50
Kinetics of the inhibition of thrombin by hirudin. Biochemistry (1986) 2.33
Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases. J Biol Chem (1981) 2.29
Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function. EMBO J (2001) 2.28
D-Phe-Pro-ArgCH2C1-A selective affinity label for thrombin. Thromb Res (1979) 2.09
Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones. Biochimie (1994) 2.07
alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure. Biochemistry (1990) 2.03
Tenascin: cDNA cloning and induction by TGF-beta. EMBO J (1988) 2.01
Inactivation of trypsin-like enzymes with peptides of arginine chloromethyl ketone. Methods Enzymol (1981) 2.00
Factors associated with complications and mortality in adult patients hospitalized for infectious cellulitis. Eur J Clin Microbiol Infect Dis (2003) 1.92
C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. J Neurosci (2001) 1.90
A BIOCHEMICAL AND PHARMACOLOGICAL SUGGESTION ABOUT CERTAIN MENTAL DISORDERS. Proc Natl Acad Sci U S A (1954) 1.85
Glia-induced morphological differentiation in neuroblastoma cells. Proc Natl Acad Sci U S A (1973) 1.82
AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity. Proc Natl Acad Sci U S A (1995) 1.80
Population screening reduces mortality rate from aortic aneurysm in men. Br J Surg (2000) 1.79
Correct folding of circularly permuted variants of a beta alpha barrel enzyme in vivo. Science (1989) 1.76
Identification of the 40 S ribosomal protein S6 phosphorylation sites induced by cycloheximide. J Biol Chem (1988) 1.72
Mitogen-activated 70K S6 kinase. Identification of in vitro 40 S ribosomal S6 phosphorylation sites. J Biol Chem (1991) 1.70
Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform. Biochemistry (1991) 1.69
The enzymic degradation of 3',5' cyclic AMP in strains of E. Coli sensitive and resistant to catobolite repression. Biochem Biophys Res Commun (1969) 1.69
Methods for measuring the three-dimensional structure of fish schools. Anim Behav (1965) 1.68
Chromatography of trypsin and its derivatives. Characterization of a new active form of bovine trypsin. J Biol Chem (1968) 1.66
cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue. Biochemistry (1991) 1.66
Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition. EMBO J (1990) 1.65
Quantitative evaluation of the contribution of ionic interactions to the formation of the thrombin-hirudin complex. Biochemistry (1989) 1.61
The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B. Biochem J (1988) 1.60
Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors. Neuron (1992) 1.60
Purification and characterization of a soluble beta-fructofuranosidase from Daucus carota. Eur J Biochem (1992) 1.59
Rapid interaction of cathepsin L by Z-Phe-PheCHN12 and Z-Phe-AlaCHN2. Biochem Biophys Res Commun (1981) 1.58
Thiobenzyl benzyloxycarbonyl-L-lysinate, substrate for a sensitive colorimetric assay for trypsin-like enzymes. Anal Biochem (1979) 1.57
Insomnia and the eye of the beholder: are there clinical markers of objective sleep disturbances among adults with and without insomnia complaints? J Consult Clin Psychol (2000) 1.57
A comparison of the behavior of chymotrypsin and cathepsin B towards peptidyl diazomethyl ketones. Biochem Biophys Res Commun (1979) 1.56
Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation. J Neurosci (1997) 1.55
Regulatory circuits involved with pH-regulated gene expression in Salmonella typhimurium. Microbiology (1994) 1.55
Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing. J Biol Chem (1993) 1.54
Sleep in the laboratory and sleep at home: comparisons of older insomniacs and normal sleepers. Sleep (1997) 1.51
The inhibition of macrophage protein turnover by a selective inhibitor of thiol proteinases. Biochem J (1980) 1.50
Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth. Trends Neurosci (1988) 1.49
Protein C-mannosylation is enzyme-catalysed and uses dolichyl-phosphate-mannose as a precursor. Mol Biol Cell (1998) 1.49
The repressor MDBP-2 is a member of the histone H1 family that binds preferentially in vitro and in vivo to methylated nonspecific DNA sequences. Proc Natl Acad Sci U S A (1992) 1.49
Photochemical Activities of Spinach Chloroplasts Following Treatment with the Detergent Triton X-100. Plant Physiol (1965) 1.44
Looking through the retrospectoscope in the era of evidence-based medicine. J Clin Oncol (1997) 1.43
Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2. J Virol (1994) 1.41
Cyclic 3',5'-adenosine monophosphate phosphodiesterase of Escherichia coli. J Bacteriol (1973) 1.39
Prothrombin mRNA is expressed by cells of the nervous system. Neuron (1991) 1.38
Affinity labelling of proteinases with tryptic specificity by peptides with C-terminal lysine chloromethyl ketone. Biochem J (1974) 1.37
Functional expression of human PP2Ac in yeast permits the identification of novel C-terminal and dominant-negative mutant forms. J Biol Chem (1999) 1.35
Protein chemical and kinetic characterization of recombinant porcine ribonuclease inhibitor expressed in Saccharomyces cerevisiae. Biochemistry (1990) 1.32
Diazomethyl ketone substrate derivatives as active-site-directed inhibitors of thiol proteases. Papain. Biochemistry (1977) 1.30
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity. J Biol Chem (2001) 1.30
The phosphatidylethanolamine-binding protein is the prototype of a novel family of serine protease inhibitors. J Biol Chem (2001) 1.30
A glia-derived neurite-promoting factor with protease inhibitory activity. EMBO J (1985) 1.26
Requirement of the Lec35 gene for all known classes of monosaccharide-P-dolichol-dependent glycosyltransferase reactions in mammals. Mol Biol Cell (2001) 1.25
New factor released by cultured glioma cells supporting survival and growth of sensory neurones. Nature (1978) 1.23
Screening for abdominal aortic aneurysms in men. BMJ (2004) 1.21
Recognition signal for C-mannosylation of Trp-7 in RNase 2 consists of sequence Trp-x-x-Trp. Mol Biol Cell (1998) 1.21
Sleep in the laboratory and sleep at home II: comparisons of middle-aged insomnia sufferers and normal sleepers. Sleep (2001) 1.21
Inhibition of protease activity can lead to neurite extension in neuroblastoma cells. Prog Brain Res (1983) 1.20
Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones. Virology (1989) 1.18
Use of site-directed mutagenesis to investigate the basis for the specificity of hirudin. Biochemistry (1988) 1.18
Degradation of substituted phenylurea herbicides by Arthrobacter globiformis strain D47 and characterization of a plasmid-associated hydrolase gene, puhA. Appl Environ Microbiol (2001) 1.17
Primary structure of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens. Biochim Biophys Acta (1982) 1.17
The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases. Biochem J (1986) 1.17
Effect of thrombomodulin on the kinetics of the interaction of thrombin with substrates and inhibitors. Biochem J (1986) 1.17
Synthesis of peptides of arginine chloromethyl ketone. Selective inactivation of human plasma kallikrein. Biochemistry (1978) 1.17
Characterization of the adenylation site in the RNA 3'-terminal phosphate cyclase from Escherichia coli. J Biol Chem (1999) 1.16
Amino acid sequence of the nonsecretory ribonuclease of human urine. Biochemistry (1988) 1.16
Inactivation of cathepsin B by active site-directed disulfide exchange. Application in covalent affinity chromatography. J Biol Chem (1983) 1.16
The RNA moiety of chick embryo 5-methylcytosine- DNA glycosylase targets DNA demethylation. Nucleic Acids Res (1997) 1.15
An exploration of the primary specificity site of cathepsin B. Arch Biochem Biophys (1983) 1.15
Occupational sunlight exposure and melanoma in the U.S. Navy. Arch Environ Health (1991) 1.14
Analysis of subunit isoforms in protein phosphatase 2A holoenzymes from rabbit and Xenopus. J Biol Chem (1993) 1.14
Novel, starch-like polysaccharides are synthesized by an unbound form of granule-bound starch synthase in glycogen-accumulating mutants of Chlamydomonas reinhardtii. Plant Physiol (1999) 1.13
The reactivity of His-57 in chymotrypsin to alkylation. Arch Biochem Biophys (1971) 1.13
Protein C-mannosylation: facts and questions. Acta Biochim Pol (2000) 1.13
A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins. Cell (1986) 1.13
The hexopyranosyl residue that is C-glycosidically linked to the side chain of tryptophan-7 in human RNase Us is alpha-mannopyranose. Biochemistry (1995) 1.13
Male fertility defects in mice lacking the serine protease inhibitor protease nexin-1. Proc Natl Acad Sci U S A (2001) 1.12
Cofactor dependence of factor Xa incorporation into the prothrombinase complex. J Biol Chem (1981) 1.12
Active center differences between cathepsins L and B: the S1 binding region. FEBS Lett (1988) 1.12
Variable and multiple expression of Protease Nexin-1 during mouse organogenesis and nervous system development. Development (1993) 1.10
A single normal ultrasonographic scan at age 65 years rules out significant aneurysm disease for life in men. Br J Surg (2001) 1.10
Healthcare-associated, community-acquired and hospital-acquired bacteraemic urinary tract infections in hospitalized patients: a prospective multicentre cohort study in the era of antimicrobial resistance. Clin Microbiol Infect (2012) 1.09
A comparison of the mortality rate after elective repair of aortic aneurysms detected either by screening or incidentally. Eur J Vasc Endovasc Surg (2000) 1.09
Phototherapy of jaundice in the newborn infant. II. Effect of various light intensities. J Pediatr (1972) 1.08
The synthesis of inhibitors for processing proteinases and their action on the Kex2 proteinase of yeast. Biochem J (1993) 1.08
Inactivation of thiol proteases with peptidyl diazomethyl ketones. Methods Enzymol (1981) 1.08
Pseudotrypsin. A modified bovine trypsin produced by limited autodigestion. J Biol Chem (1969) 1.07
Identification of the histidine residue at the active center of trypsin labelled by TLCK. Biochem Biophys Res Commun (1967) 1.07
Inactivation of cathepsin B1 by diazomethyl ketones. Biochem Biophys Res Commun (1977) 1.07
Specificity of activated human protein C. Biochem J (1985) 1.06
Further observations on substrate-derived chloromethyl ketones that inactivate trypsin. Arch Biochem Biophys (1970) 1.05
Identification of regions of alpha-thrombin involved in its interaction with hirudin. Biochemistry (1987) 1.04