Published in Neurobiol Aging on February 14, 2013
PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia. Acta Neuropathol (2015) 0.97
Role of endoplasmic reticulum stress in atherosclerosis and diabetic macrovascular complications. Biomed Res Int (2014) 0.94
The unfolded protein response mediates reversible tau phosphorylation induced by metabolic stress. Cell Death Dis (2014) 0.90
Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders. Autophagy (2016) 0.88
Roles of tau protein in health and disease. Acta Neuropathol (2017) 0.80
Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice. Brain (2017) 0.76
PERK activation mitigates tau pathology in vitro and in vivo. EMBO Mol Med (2017) 0.75
Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology. Acta Neuropathol Commun (2016) 0.75
Fine tuning PERK signaling for neuroprotection. J Neurochem (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus. Am J Pathol (2009) 1.92
The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies. J Pathol (2012) 1.76
Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer's disease. Neurodegener Dis (2010) 1.66
Automated analysis of neuronal morphology, synapse number and synaptic recruitment. J Neurosci Methods (2010) 1.36
Pontocerebellar hypoplasia type 2: a neuropathological update. Acta Neuropathol (2007) 1.32
Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy. Antioxid Redox Signal (2011) 1.29
Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner. Antioxid Redox Signal (2007) 1.23
Oligomer-specific Abeta toxicity in cell models is mediated by selective uptake. Biochim Biophys Acta (2008) 1.14
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis. Neurobiol Dis (2005) 1.14
Endoplasmic reticulum protein quality control in neurodegenerative disease: the good, the bad and the therapy. Curr Med Chem (2009) 1.14
Matrix metalloproteinase-12 is expressed in phagocytotic macrophages in active multiple sclerosis lesions. J Neuroimmunol (2003) 1.14
Microglia activation in sepsis: a case-control study. J Neuroinflammation (2007) 1.13
Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission. EMBO J (2012) 1.11
A closer look at FBXO41 as a Parkinson's disease risk factor. Parkinsonism Relat Disord (2013) 1.09
The unfolded protein response in neurodegenerative diseases: a neuropathological perspective. Acta Neuropathol (2015) 1.05
Matrix-dependent local retention of secretory vesicle cargo in cortical neurons. J Neurosci (2009) 1.03
Activation of the unfolded protein response is an early event in Alzheimer's and Parkinson's disease. Neurodegener Dis (2012) 1.01
DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid. J Neurosci (2006) 0.99
The pre-eclampsia gene STOX1 controls a conserved pathway in placenta and brain upregulated in late-onset Alzheimer's disease. J Alzheimers Dis (2010) 0.99
Protein translocation across the endoplasmic reticulum membrane in cold-adapted organisms. J Cell Sci (2003) 0.98
Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. J Cell Biol (2013) 0.97
Transglutaminases and transglutaminase-catalyzed cross-links colocalize with the pathological lesions in Alzheimer's disease brain. Brain Pathol (2008) 0.96
Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release. Elife (2014) 0.96
CX3CL1 and CX3CR1 expression in human brain tissue: noninflammatory control versus multiple sclerosis. J Neuropathol Exp Neurol (2003) 0.96
The unfolded protein response and proteostasis in Alzheimer disease: preferential activation of autophagy by endoplasmic reticulum stress. Autophagy (2011) 0.95
Endoplasmic reticulum: the unfolded protein response is tangled in neurodegeneration. Int J Biochem Cell Biol (2012) 0.95
Vesicular trafficking of semaphorin 3A is activity-dependent and differs between axons and dendrites. Traffic (2006) 0.95
CC chemokine receptor 5 gene promoter activation by the cyclic AMP response element binding transcription factor. Blood (2008) 0.94
Stages of granulovacuolar degeneration: their relation to Alzheimer's disease and chronic stress response. Acta Neuropathol (2011) 0.93
Ca(2+)-induced recruitment of the secretory vesicle protein DOC2B to the target membrane. J Biol Chem (2004) 0.93
Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases. Arch Toxicol (2014) 0.92
Versatile and efficient targeting using a single nanoparticulate platform: application to cancer and Alzheimer's disease. ACS Nano (2012) 0.91
Cholinergic imbalance in the multiple sclerosis hippocampus. Acta Neuropathol (2011) 0.91
Branched KLVFF tetramers strongly potentiate inhibition of beta-amyloid aggregation. Chembiochem (2007) 0.91
Presence of tissue transglutaminase in granular endoplasmic reticulum is characteristic of melanized neurons in Parkinson's disease brain. Brain Pathol (2010) 0.90
Interleukin-1 beta-induced expression of the prostaglandin E-receptor subtype EP3 in U373 astrocytoma cells depends on protein kinase C and nuclear factor-kappaB. J Neurochem (2006) 0.90
The role of Rab3a in secretory vesicle docking requires association/dissociation of guanidine phosphates and Munc18-1. PLoS One (2007) 0.89
Characteristics of dyshoric capillary cerebral amyloid angiopathy. J Neuropathol Exp Neurol (2010) 0.89
Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease. J Neuroinflammation (2005) 0.89
Munc18 and Munc13 regulate early neurite outgrowth. Biol Cell (2010) 0.87
Neuroinflammation and blood-brain barrier changes in capillary amyloid angiopathy. Neurodegener Dis (2012) 0.87
Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner. J Cell Biol (2014) 0.87
PEGylated nanoparticles bind to and alter amyloid-beta peptide conformation: toward engineering of functional nanomedicines for Alzheimer's disease. ACS Nano (2012) 0.86
Automated quantification of cellular traffic in living cells. J Neurosci Methods (2008) 0.86
Amyloid beta peptide (25-35) activates protein kinase C leading to cyclooxygenase-2 induction and prostaglandin E2 release in primary midbrain astrocytes. Neurochem Int (2006) 0.86
Ubiquitin proteasome system as a pharmacological target in neurodegeneration. Expert Rev Neurother (2006) 0.86
Neuroinflammation in plaque and vascular beta-amyloid disorders: clinical and therapeutic implications. Neurodegener Dis (2008) 0.85
The nature of the cell cycle in neurons: focus on a "non-canonical" pathway of DNA replication causally related to death. Biochim Biophys Acta (2006) 0.85
Novel role of transglutaminase 1 in corpora amylacea formation? Neurobiol Aging (2009) 0.85
Munc13 controls the location and efficiency of dense-core vesicle release in neurons. J Cell Biol (2012) 0.84
Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome. Age (Dordr) (2012) 0.84
Rab6 is a modulator of the unfolded protein response: implications for Alzheimer's disease. J Alzheimers Dis (2012) 0.83
Innate immunity and the etiology of late-onset Alzheimer's disease. Neurodegener Dis (2012) 0.82
Neuroinflammation in Alzheimer's disease wanes with age. J Neuroinflammation (2011) 0.82
Adult human microglia secrete cytokines when exposed to neurotoxic prion protein peptide: no intermediary role for prostaglandin E2. Brain Res (2002) 0.82
The unfolded protein response affects neuronal cell cycle protein expression: implications for Alzheimer's disease pathogenesis. Exp Gerontol (2006) 0.82
Increased expression of the oligopeptidase THOP1 is a neuroprotective response to Abeta toxicity. Neurobiol Dis (2008) 0.82
Mice lacking basic fibroblast growth factor showed faster sensory recovery. Exp Neurol (2009) 0.82
Fibroblast growth factor-2 regulates the stability of nuclear bodies. Proc Natl Acad Sci U S A (2009) 0.82
Quantification of amyloid-beta 40 in cerebrospinal fluid. J Immunol Methods (2009) 0.81
Correction: CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons. Elife (2015) 0.80
Ubiquilin 2 is not associated with tau pathology. PLoS One (2013) 0.80
Pin1 levels are downregulated during ER stress in human neuroblastoma cells. Neurogenetics (2006) 0.79
Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment. Acta Neuropathol Commun (2013) 0.79
Inhibition of endoplasmic reticulum associated degradation reduces endoplasmic reticulum stress and alters lysosomal morphology and distribution. Mol Cells (2013) 0.79
Physiological and pathophysiological functions of cell cycle proteins in post-mitotic neurons: implications for Alzheimer's disease. Acta Neuropathol (2015) 0.79
STOX1A induces phosphorylation of tau proteins at epitopes hyperphosphorylated in Alzheimer's disease. Neurosci Lett (2012) 0.79
Morphometric changes in the cortical microvascular network in Alzheimer's disease. J Alzheimers Dis (2010) 0.78
Apolipoprotein E and LRP1 Increase Early in Parkinson's Disease Pathogenesis. Am J Pathol (2011) 0.78
A new PERKspective on neurodegeneration. Sci Transl Med (2013) 0.78
New method based on capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) to monitor interaction between nanoparticles and the amyloid-β peptide. Anal Chem (2010) 0.78
Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q. Neurobiol Dis (2005) 0.78
Disturbed Ca2+ homeostasis increases glutaminyl cyclase expression; connecting two early pathogenic events in Alzheimer's disease in vitro. PLoS One (2012) 0.78
Neuroinflammation and common mechanism in Alzheimer's disease and prion amyloidosis: amyloid-associated proteins, neuroinflammation and neurofibrillary degeneration. Neurodegener Dis (2012) 0.77
Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid β-peptide. Amyloid (2013) 0.77
Simvastatin affects cell motility and actin cytoskeleton distribution of microglia. Glia (2006) 0.77
Stability of Aβ (1-42) peptide fibrils as consequence of environmental modifications. Eur Biophys J (2010) 0.76
Adult neurogenesis and the unfolded protein response; new cellular and molecular avenues in sleep research. Sleep Med Rev (2009) 0.75