Published in J Immunol on February 25, 2013
Developmental gene networks: a triathlon on the course to T cell identity. Nat Rev Immunol (2014) 1.14
Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment. Cold Spring Harb Symp Quant Biol (2013) 0.79
Bottlenecks in deriving definitive hematopoietic stem cells from human pluripotent stem cells: a CIRM mini-symposium and workshop report. Stem Cells Transl Med (2014) 0.76
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods (2008) 126.81
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res (2002) 76.95
R/qtl: QTL mapping in experimental crosses. Bioinformatics (2003) 22.38
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science (2004) 18.84
Computation for ChIP-seq and RNA-seq studies. Nat Methods (2009) 16.11
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity (2002) 8.17
The NOD mouse: a model of immune dysregulation. Annu Rev Immunol (2005) 6.71
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell (2002) 6.64
Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol (2009) 4.89
A nonparametric approach for mapping quantitative trait loci. Genetics (1995) 4.49
A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J Immunol (1993) 4.44
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat Immunol (2001) 3.89
Launching the T-cell-lineage developmental programme. Nat Rev Immunol (2008) 3.86
Molecular pathogenesis of T-cell leukaemia and lymphoma. Nat Rev Immunol (2008) 3.57
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity (1997) 3.44
Multistep pathogenesis of autoimmune disease. Cell (2007) 3.36
Zoned out: functional mapping of stromal signaling microenvironments in the thymus. Annu Rev Immunol (2007) 2.98
Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity (2004) 2.84
The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal. Science (2010) 2.64
The actin cytoskeleton in T cell activation. Annu Rev Immunol (2008) 2.62
Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo. Genes Dev (1996) 2.47
An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. Science (2010) 2.42
Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity. Cell (2012) 2.38
The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. Proc Natl Acad Sci U S A (1992) 2.28
An essential developmental checkpoint for production of the T cell lineage. Science (2010) 2.01
Polygenic control of autoimmune diabetes in nonobese diabetic mice. Nat Genet (1993) 1.98
The TLX1 oncogene drives aneuploidy in T cell transformation. Nat Med (2010) 1.93
Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models. Immunity (2001) 1.72
NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol (2000) 1.70
Crosses of NOD mice with the related NON strain. A polygenic model for IDDM. Diabetes (1995) 1.50
The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia. Blood (2011) 1.45
Signal integration and crosstalk during thymocyte migration and emigration. Nat Rev Immunol (2011) 1.45
Transcription factor expression dynamics of early T-lymphocyte specification and commitment. Dev Biol (2008) 1.42
Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs. Proc Natl Acad Sci U S A (1997) 1.41
The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137. Immunity (2000) 1.40
Multilayered specification of the T-cell lineage fate. Immunol Rev (2010) 1.32
Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice. Curr Dir Autoimmun (2001) 1.32
Fine-scale staging of T cell lineage commitment in adult mouse thymus. J Immunol (2010) 1.25
On the brink of becoming a T cell. Curr Opin Immunol (2002) 1.21
Investigating spatio-temporal similarities in the epidemiology of childhood leukaemia and diabetes. Eur J Epidemiol (2009) 1.13
After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies. Blood (2004) 1.09
Cancer risk among patients hospitalized for Type 1 diabetes mellitus: a population-based cohort study in Sweden. Diabet Med (2010) 1.07
Thymic negative selection is functional in NOD mice. J Exp Med (2012) 1.00
Deranged early T cell development in immunodeficient strains of nonobese diabetic mice. J Immunol (2004) 0.98
Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice. J Proteome Res (2010) 0.96
Susceptibility to lymphoid neoplasia in immunodeficient strains of nonobese diabetic mice. Cancer Res (2002) 0.95
Allelic variation in class I K gene as candidate for a second component of MHC-linked susceptibility to type 1 diabetes in non-obese diabetic mice. Diabetologia (2004) 0.90
An interval tightly linked to but distinct from the H2 complex controls both overt diabetes (Idd16) and chronic experimental autoimmune thyroiditis (Ceat1) in nonobese diabetic mice. Diabetes (2002) 0.88
Localization of Idd11 using NOD congenic mouse strains: elimination of Slc9a1 as a candidate gene. Immunogenetics (2000) 0.86
Lineage divergence at the first TCR-dependent checkpoint: preferential γδ and impaired αβ T cell development in nonobese diabetic mice. J Immunol (2010) 0.78
Congenic mapping of the MHC-linked susceptibility to type 1 diabetes in the NOD mouse: at least two genes contribute to the Idd16 effect. Ann N Y Acad Sci (2008) 0.76
Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus. Immunity (2006) 3.39
GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation. Immunity (2003) 2.63
Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Nat Immunol (2007) 2.58
Bacteria-induced intestinal cancer in mice with disrupted Gpx1 and Gpx2 genes. Cancer Res (2004) 2.42
An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. Science (2010) 2.42
Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity. Cell (2012) 2.38
Positive feedback between PU.1 and the cell cycle controls myeloid differentiation. Science (2013) 2.31
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling. Genes Dev (2005) 1.98
Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses. Mol Cell Biol (2003) 1.80
Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway. J Immunol (2007) 1.79
A far downstream enhancer for murine Bcl11b controls its T-cell specific expression. Blood (2013) 1.69
Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification. Blood (2008) 1.67
A gene regulatory network armature for T lymphocyte specification. Proc Natl Acad Sci U S A (2008) 1.58
Constitutive expression of PU.1 in fetal hematopoietic progenitors blocks T cell development at the pro-T cell stage. Immunity (2002) 1.54
Transcription factor expression dynamics of early T-lymphocyte specification and commitment. Dev Biol (2008) 1.42
Pillars Article: Polygenic Control of Susceptibility to Murine Systemic Lupus Erythematosus. Immunity. 1994. 1: 219-229. J Immunol (2015) 1.42
Notch/Delta signaling constrains reengineering of pro-T cells by PU.1. Proc Natl Acad Sci U S A (2006) 1.39
Fine-scale staging of T cell lineage commitment in adult mouse thymus. J Immunol (2010) 1.25
Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes. J Immunol (2004) 1.23
The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors. J Immunol (2006) 1.21
Cell-type-specific epigenetic marking of the IL2 gene at a distal cis-regulatory region in competent, nontranscribing T-cells. Nucleic Acids Res (2005) 1.20
Definition of regulatory network elements for T cell development by perturbation analysis with PU.1 and GATA-3. Dev Biol (2002) 1.17
Progression of regulatory gene expression states in fetal and adult pro-T-cell development. Immunol Rev (2006) 1.15
Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors. Curr Opin Immunol (2003) 1.11
Cell-type-specific activation and repression of PU.1 by a complex of discrete, functionally specialized cis-regulatory elements. Mol Cell Biol (2010) 1.05
Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3. Development (2013) 1.02
Deranged early T cell development in immunodeficient strains of nonobese diabetic mice. J Immunol (2004) 0.98
Subversion of T lineage commitment by PU.1 in a clonal cell line system. Dev Biol (2005) 0.98
Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques. J Virol (2010) 0.95
Hepatitis C virus genotype 1b core protein does not exert immunomodulatory effects on virus-induced cellular immunity. J Virol (2002) 0.94
Phase II study of oxaliplatin in patients with unresectable, metastatic, or recurrent hepatocellular cancer: a California Cancer Consortium Trial. Am J Clin Oncol (2008) 0.91
Regulatory gene network circuits underlying T cell development from multipotent progenitors. Wiley Interdiscip Rev Syst Biol Med (2011) 0.91
Preferential activation of an IL-2 regulatory sequence transgene in TCR gamma delta and NKT cells: subset-specific differences in IL-2 regulation. J Immunol (2004) 0.89
Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development. Semin Immunopathol (2008) 0.88
Phase I study of pazopanib in patients with advanced solid tumors and hepatic dysfunction: a National Cancer Institute Organ Dysfunction Working Group study. Clin Cancer Res (2013) 0.87
Evolutionary origins of lymphocytes: ensembles of T cell and B cell transcriptional regulators in a cartilaginous fish. J Immunol (2004) 0.86
Analysis of imprinting in mice with uniparental duplication of proximal chromosomes 7 and 15 by use of a custom oligonucleotide microarray. Mamm Genome (2004) 0.84
Computational modelling of T-cell formation kinetics: output regulated by initial proliferation-linked deferral of developmental competence. J R Soc Interface (2013) 0.83
Toxicity equivalence range design (TEQR): a practical Phase I design. Contemp Clin Trials (2010) 0.83
T-cell identity and epigenetic memory. Curr Top Microbiol Immunol (2012) 0.82
Altered neuroantigen-specific cytokine secretion in a Th2 environment reduces experimental autoimmune encephalomyelitis. J Neuroimmunol (2006) 0.80
11beta-hydroxysteroid dehydrogenase type 2 in zebra finch brain and peripheral tissues. Gen Comp Endocrinol (2010) 0.79
Lineage divergence at the first TCR-dependent checkpoint: preferential γδ and impaired αβ T cell development in nonobese diabetic mice. J Immunol (2010) 0.78
Erg in stem cells: a function emerges. Nat Immunol (2008) 0.75
Factors That Influence the Quality of RNA From the Pancreas of Organ Donors. Pancreas (2016) 0.75
Immune Cell Identity: Perspective from a Palimpsest. Perspect Biol Med (2015) 0.75
B cell specification from the genome up. Nat Immunol (2010) 0.75
From totipotency to T in a dish. Nat Immunol (2004) 0.75
[Effects of acupoint-injection of Lentinan on the immunologic funtion in rabbits with spleen-qi deficiency]. Zhen Ci Yan Jiu (2010) 0.75
Current Opinion in Immunology. Editorial overview. Curr Opin Immunol (2010) 0.75