PubRank

Jan Potempa

Author PubWeight™ 147.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 New method for typing Staphylococcus aureus strains: multiple-locus variable-number tandem repeat analysis of polymorphism and genetic relationships of clinical isolates. J Clin Microbiol 2003 2.96
2 Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis. Arthritis Rheum 2010 2.53
3 Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases. Antimicrob Agents Chemother 2004 2.34
4 A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages. PLoS One 2008 2.12
5 The role and regulation of the extracellular proteases of Staphylococcus aureus. Microbiology 2004 1.70
6 Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins. Periodontol 2000 2010 1.65
7 Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria? J Bacteriol 2006 1.56
8 Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system. J Immunol 2007 1.50
9 Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalis. Mol Microbiol 2002 1.42
10 Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors. PLoS One 2009 1.41
11 Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection. PLoS Pathog 2006 1.35
12 Sequential autolytic processing activates the zymogen of Arg-gingipain. J Biol Chem 2003 1.27
13 On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator. J Biol Chem 2004 1.25
14 Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD). PLoS Pathog 2013 1.22
15 Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells. Infect Immun 2005 1.21
16 The biphasic virulence activities of gingipains: activation and inactivation of host proteins. Curr Protein Pept Sci 2003 1.21
17 The link between periodontal disease and rheumatoid arthritis: an updated review. Curr Rheumatol Rep 2014 1.20
18 Identification and characterization of sigma, a novel component of the Staphylococcus aureus stress and virulence responses. PLoS One 2008 1.19
19 Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis. Ann Rheum Dis 2013 1.18
20 Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases. Mol Microbiol 2003 1.17
21 Investigations into sigmaB-modulated regulatory pathways governing extracellular virulence determinant production in Staphylococcus aureus. J Bacteriol 2006 1.17
22 Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73. Cell Cycle 2010 1.17
23 Comparison of gingival crevicular fluid sampling methods in patients with severe chronic periodontitis. J Periodontol 2011 1.17
24 Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3. PLoS Pathog 2009 1.16
25 Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host. Periodontol 2000 2010 1.15
26 High molecular weight gingipains from Porphyromonas gingivalis induce cytokine responses from human macrophage-like cells via a nonproteolytic mechanism. J Innate Immun 2008 1.15
27 Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis. J Immunol 2008 1.14
28 NsaRS is a cell-envelope-stress-sensing two-component system of Staphylococcus aureus. Microbiology 2011 1.13
29 Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipains. Infect Immun 2002 1.12
30 A new pathway of staphylococcal pathogenesis: apoptosis-like death induced by Staphopain B in human neutrophils and monocytes. J Innate Immun 2008 1.10
31 Verification of a topology model of PorT as an integral outer-membrane protein in Porphyromonas gingivalis. Microbiology 2009 1.09
32 Porphyromonas gingivalis HmuY and HmuR: further characterization of a novel mechanism of heme utilization. Arch Microbiol 2007 1.08
33 A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037. Biol Chem 2010 1.08
34 A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system. J Immunol 2012 1.07
35 Three-dimensional structure of MecI. Molecular basis for transcriptional regulation of staphylococcal methicillin resistance. J Biol Chem 2003 1.07
36 Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus. J Exp Med 2005 1.04
37 Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis. Infect Immun 2006 1.03
38 Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis? Arthritis Res Ther 2010 1.03
39 Staphylococcal proteases aid in evasion of the human complement system. J Innate Immun 2013 1.02
40 Proteolysis of CD14 on human gingival fibroblasts by arginine-specific cysteine proteinases from Porphyromonas gingivalis leading to down-regulation of lipopolysaccharide-induced interleukin-8 production. Infect Immun 2002 1.02
41 A new autocatalytic activation mechanism for cysteine proteases revealed by Prevotella intermedia interpain A. J Biol Chem 2007 1.01
42 Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis. Infect Immun 2005 1.01
43 Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin. J Immunol 2007 1.01
44 Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB). J Biol Chem 2013 1.01
45 Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism. BMC Microbiol 2009 1.00
46 Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus. Microbes Infect 2012 0.99
47 The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease. J Biol Chem 2003 0.99
48 Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases. J Med Chem 2004 0.99
49 Unique structure and stability of HmuY, a novel heme-binding protein of Porphyromonas gingivalis. PLoS Pathog 2009 0.98
50 Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages. Biol Chem 2009 0.97
51 Papain-like proteases of Staphylococcus aureus. Adv Exp Med Biol 2011 0.96
52 Sequential action of R- and K-specific gingipains of Porphyromonas gingivalis in the generation of the haem-containing pigment from oxyhaemoglobin. Arch Biochem Biophys 2007 0.96
53 The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities. Mol Microbiol 2004 0.96
54 Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition. Biochemistry 2004 0.95
55 The Clostridium ramosum IgA proteinase represents a novel type of metalloendopeptidase. J Biol Chem 2002 0.95
56 Regulation of chemerin chemoattractant and antibacterial activity by human cysteine cathepsins. J Immunol 2011 0.95
57 The structure of the catalytic domain of Tannerella forsythia karilysin reveals it is a bacterial xenologue of animal matrix metalloproteinases. Mol Microbiol 2010 0.95
58 Functional and structural characterization of Spl proteases from Staphylococcus aureus. J Mol Biol 2006 0.95
59 Role of the cysteine protease interpain A of Prevotella intermedia in breakdown and release of haem from haemoglobin. Biochem J 2009 0.95
60 Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis. J Immunol 2009 0.94
61 HmuY haemophore and gingipain proteases constitute a unique syntrophic system of haem acquisition by Porphyromonas gingivalis. PLoS One 2011 0.94
62 Sequence-independent processing site of the C-terminal domain (CTD) influences maturation of the RgpB protease from Porphyromonas gingivalis. Mol Microbiol 2013 0.94
63 Protease-dependent mechanisms of complement evasion by bacterial pathogens. Biol Chem 2012 0.94
64 The lysine-specific gingipain of Porphyromonas gingivalis : importance to pathogenicity and potential strategies for inhibition. Adv Exp Med Biol 2011 0.93
65 Proteolytic inactivation of LL-37 by karilysin, a novel virulence mechanism of Tannerella forsythia. J Innate Immun 2010 0.93
66 Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus. Microbiology 2010 0.93
67 Elafin is specifically inactivated by RgpB from Porphyromonas gingivalis by distinct proteolytic cleavage. Biol Chem 2009 0.92
68 Proteinase-mediated release of epithelial cell-associated CD44. Extracellular CD44 complexes with components of cellular matrices. J Biol Chem 2002 0.92
69 Molecular diversity of a putative virulence factor: purification and characterization of isoforms of an extracellular serine glutamyl endopeptidase of Enterococcus faecalis with different enzymatic activities. J Bacteriol 2005 0.92
70 Cleavage of IgG1 and IgG3 by gingipain K from Porphyromonas gingivalis may compromise host defense in progressive periodontitis. FASEB J 2011 0.91
71 Porphyromonas gingivalis virulence factor gingipain RgpB shows a unique zymogenic mechanism for cysteine peptidases. J Biol Chem 2013 0.91
72 Genome Sequence of Porphyromonas gingivalis Strain HG66 (DSM 28984). Genome Announc 2014 0.91
73 Diagnostic evaluation of a nanobody with picomolar affinity toward the protease RgpB from Porphyromonas gingivalis. Anal Biochem 2011 0.91
74 Inactivation of epidermal growth factor by Porphyromonas gingivalis as a potential mechanism for periodontal tissue damage. Infect Immun 2012 0.90
75 Adsorption of components of the plasma kinin-forming system on the surface of Porphyromonas gingivalis involves gingipains as the major docking platforms. Infect Immun 2010 0.90
76 Cytoplasmic control of premature activation of a secreted protease zymogen: deletion of staphostatin B (SspC) in Staphylococcus aureus 8325-4 yields a profound pleiotropic phenotype. J Bacteriol 2005 0.90
77 Mechanism of methaemoglobin breakdown by the lysine-specific gingipain of the periodontal pathogen Porphyromonas gingivalis. Biol Chem 2008 0.90
78 Arginine-specific gingipains from Porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter factor) through protease-activated receptors in human gingival fibroblasts in culture. J Immunol 2005 0.90
79 The human fibrinolytic system is a target for the staphylococcal metalloprotease aureolysin. Biochem J 2008 0.90
80 Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase. J Biol Chem 2006 0.89
81 Gingipain aminopeptidase activities in Porphyromonas gingivalis. Biol Chem 2012 0.88
82 Ribonucleotide reductase class III, an essential enzyme for the anaerobic growth of Staphylococcus aureus, is a virulence determinant in septic arthritis. Microb Pathog 2007 0.88
83 Prokaryote-derived protein inhibitors of peptidases: A sketchy occurrence and mostly unknown function. Biochimie 2010 0.88
84 Dual regulation of interleukin-8 production in human oral epithelial cells upon stimulation with gingipains from Porphyromonas gingivalis. J Med Microbiol 2008 0.88
85 Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases. Biochim Biophys Acta 2013 0.87
86 Neuropeptide release from dental pulp cells by RgpB via proteinase-activated receptor-2 signaling. J Immunol 2005 0.87
87 Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus. Biochem J 2009 0.86
88 Prevalence of genes encoding extracellular proteases in Staphylococcus aureus - important targets triggering immune response in vivo. FEMS Immunol Med Microbiol 2012 0.86
89 Activation of the kallikrein-kinin system and release of new kinins through alternative cleavage of kininogens by microbial and human cell proteinases. Biol Chem 2004 0.86
90 Secretory leukocyte proteinase inhibitor-competent DNA deposits are potent stimulators of plasmacytoid dendritic cells: implication for psoriasis. J Immunol 2012 0.86
91 Staphostatins resemble lipocalins, not cystatins in fold. Protein Sci 2003 0.85
92 Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR. Biol Chem 2004 0.85
93 Characterization of the specificity of arginine-specific gingipains from Porphyromonas gingivalis reveals active site differences between different forms of the enzymes. Biochemistry 2003 0.84
94 Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln. J Mol Biol 2008 0.84
95 Bacterial proteases in disease - role in intracellular survival, evasion of coagulation/ fibrinolysis innate defenses, toxicoses and viral infections. Curr Pharm Des 2013 0.84
96 Lack of cathelicidin processing in Papillon-Lefèvre syndrome patients reveals essential role of LL-37 in periodontal homeostasis. Orphanet J Rare Dis 2014 0.84
97 Proteolysis of interleukin-6 receptor (IL-6R) by Porphyromonas gingivalis cysteine proteinases (gingipains) inhibits interleukin-6-mediated cell activation. Microb Pathog 2002 0.84
98 In vivo sortase A and clumping factor A mRNA expression during Staphylococcus aureus infection. Microb Pathog 2007 0.84
99 Protease-armed bacteria in the skin. Cell Tissue Res 2012 0.84
100 Dentipain, a Streptococcus pyogenes IdeS protease homolog, is a novel virulence factor of Treponema denticola. Biol Chem 2010 0.83
101 Filifactor alocis infection and inflammatory responses in the mouse subcutaneous chamber model. Infect Immun 2013 0.83
102 Lysine-specific gingipain promotes lipopolysaccharide- and active-vitamin D3-induced osteoclast differentiation by degrading osteoprotegerin. Biochem J 2009 0.83
103 The role of Mcl-1 in S. aureus-induced cytoprotection of infected macrophages. Mediators Inflamm 2013 0.83
104 A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus. Biochemistry 2003 0.83
105 A comparison of staphostatin B with standard mechanism serine protease inhibitors. J Biol Chem 2005 0.83
106 Inhibition of arginine gingipains (RgpB and HRgpA) with benzamidine inhibitors: zinc increases inhibitory potency. Biol Chem 2002 0.83
107 Disruption of gingipain oligomerization into non-covalent cell-surface attached complexes. Biol Chem 2012 0.82
108 Release of a new vascular permeability enhancing peptide from kininogens by human neutrophil elastase. Biochem Biophys Res Commun 2002 0.82
109 Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion. J Innate Immun 2014 0.82
110 The Staphylococcus aureus leucine aminopeptidase is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine. Biol Chem 2013 0.81
111 Isolation and properties of extracellular proteinases of Penicillium marneffei. Biol Chem 2006 0.81
112 Staphylococcus aureus proteases degrade lung surfactant protein A potentially impairing innate immunity of the lung. J Innate Immun 2012 0.81
113 Effects of elastase and cathepsin G on the levels of membrane and soluble TNFalpha. Biol Chem 2005 0.81
114 Genetic characterization of staphopain genes in Staphylococcus aureus. Biol Chem 2004 0.81
115 Use of sensitive, broad-spectrum molecular assays and human airway epithelium cultures for detection of respiratory pathogens. PLoS One 2012 0.81
116 Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis. Infect Immun 2014 0.81
117 Friendly fire against neutrophils: proteolytic enzymes confuse the recognition of apoptotic cells by macrophages. Biochimie 2007 0.81
118 Carbamylation of immunoglobulin abrogates activation of the classical complement pathway. Eur J Immunol 2014 0.81
119 Inhibition of GSK3 abolishes bacterial-induced periodontal bone loss in mice. Mol Med 2012 0.81
120 Growth phase-dependent production of a cell wall-associated elastinolytic cysteine proteinase by Staphylococcus epidermidis. Biol Chem 2004 0.80
121 Down-regulation of human extracellular cysteine protease inhibitors by the secreted staphylococcal cysteine proteases, staphopain A and B. Biol Chem 2007 0.80
122 Acquisition of complement inhibitor serine protease factor I and its cofactors C4b-binding protein and factor H by Prevotella intermedia. PLoS One 2012 0.80
123 Human SCCA serpins inhibit staphylococcal cysteine proteases by forming classic "serpin-like" covalent complexes. Methods Enzymol 2011 0.80
124 Characterisation of a highly specific, endogenous inhibitor of cysteine protease from Staphylococcus epidermidis, a new member of the staphostatin family. Biol Chem 2004 0.80
125 Infection with human coronavirus NL63 enhances streptococcal adherence to epithelial cells. J Gen Virol 2011 0.80
126 Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia. Biol Chem 2015 0.80
127 [The presence of apoptotic neutrophils in contents of neck lateral cysts]. Przegl Lek 2010 0.79
128 Selective inhibition of Porphyromonas gingivalis growth by a factor Xa inhibitor, DX-9065a. J Periodontal Res 2006 0.79
129 Glutaminyl cyclases as novel targets for the treatment of septic arthritis. J Infect Dis 2012 0.78
130 Interaction of a novel form of Pseudomonas aeruginosa alkaline protease (aeruginolysin) with interleukin-6 and interleukin-8. Biol Chem 2006 0.78
131 Inhibition of tumor necrosis factor-alpha-induced RANTES secretion by alkaline protease in A549 cells. Am J Respir Cell Mol Biol 2005 0.78
132 Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C. Biochimie 2011 0.78
133 Novel polymeric inhibitors of HCoV-NL63. Antiviral Res 2012 0.78
134 Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C. Biochim Biophys Acta 2013 0.78
135 A phage display selected 7-mer peptide inhibitor of the Tannerella forsythia metalloprotease-like enzyme Karilysin can be truncated to Ser-Trp-Phe-Pro. PLoS One 2012 0.78
136 Inhibition of Staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence. Biol Chem 2011 0.78
137 Structure of the catalytic domain of the Tannerella forsythia matrix metallopeptidase karilysin in complex with a tetrapeptidic inhibitor. Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 0.78
138 Exploring the Sn binding pockets in gingipains by newly developed inhibitors: structure-based design, chemistry, and activity. J Med Chem 2006 0.77
139 Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas gingivalis. J Innate Immun 2015 0.77
140 MCPIP-1, Alias Regnase-1, Controls Epithelial Inflammation by Posttranscriptional Regulation of IL-8 Production. J Innate Immun 2016 0.77
141 The Janus face of α-toxin: a potent mediator of cytoprotection in staphylococci-infected macrophages. J Innate Immun 2014 0.76
142 Biochemical and structural characterization of SplD protease from Staphylococcus aureus. PLoS One 2013 0.76
143 Development of loop-mediated isothermal amplification assay for detection of human coronavirus-NL63. J Virol Methods 2011 0.76
144 Staphylococcus aureus infection triggers production of neutralizing, V8 protease-specific antibodies. FEMS Immunol Med Microbiol 2008 0.76
145 Apoptotic cell clearance in chronic inflammation of lateral neck cysts. Eur Arch Otorhinolaryngol 2011 0.75
146 Porphyromonas gingivalis enzymes enhance infection with human metapneumovirus in vitro. J Gen Virol 2011 0.75
147 Correction: Pyocycanin, a Contributory Factor in Haem Acquisition and Virulence Enhancement of Porphyromonas gingivalis in the Lung. PLoS One 2016 0.75
148 Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus. Protein Sci 2013 0.75
149 Grafting of antibodies inside integrated microfluidic-microoptic devices by means of automated microcontact printing. Sens Actuators B Chem 2009 0.75
150 Purification and characterisation of recombinant His-tagged RgpB gingipain from Porphymonas gingivalis. Biol Chem 2015 0.75
151 HexaPrime: a novel method for detection of coronaviruses. J Virol Methods 2012 0.75
152 Posttranslational modifications in innate immunity. J Innate Immun 2012 0.75
153 The staphostatin family of cysteine protease inhibitors in the genus Staphylococcus as an example of parallel evolution of protease and inhibitor specificity. Biol Chem 2007 0.75
154 [Identification of Staphylococcus aureus in homogenates of hypertrophic adenoid (a preliminary report)]. Przegl Lek 2010 0.75
155 Attenuated kinin release from human neutrophil elastase-pretreated kininogens by tissue and plasma kallikreins. Biol Chem 2003 0.75
156 1H, 15N and 13C NMR resonance assignments of staphostatin A, a specific Staphylococcus aureus cysteine proteinase inhibitor. J Biomol NMR 2004 0.75
157 Relationship between past myocardial infarction, periodontal disease and Porphyromonas gingivalis serum antibodies: A case-control study. Cardiol J 2017 0.75