Published in PLoS One on March 13, 2013
Examining the role of common genetic variants on alcohol, tobacco, cannabis and illicit drug dependence: genetics of vulnerability to drug dependence. Addiction (2015) 1.01
Genetic risk prediction and neurobiological understanding of alcoholism. Transl Psychiatry (2014) 0.97
Dissecting ancestry genomic background in substance dependence genome-wide association studies. Pharmacogenomics (2015) 0.84
Causal Role of Alcohol Consumption in an Improved Lipid Profile: The Atherosclerosis Risk in Communities (ARIC) Study. PLoS One (2016) 0.79
Genome-wide association discoveries of alcohol dependence. Am J Addict (2014) 0.78
Shared additive genetic influences on DSM-IV criteria for alcohol dependence in subjects of European ancestry. Addiction (2015) 0.77
Overview of the Genetics of Alcohol Use Disorder. Alcohol Alcohol (2016) 0.76
Convergent functional genomics in addiction research - a translational approach to study candidate genes and gene networks. In Silico Pharmacol (2013) 0.76
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Inference of population structure using multilocus genotype data. Genetics (2000) 147.76
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
The genetics of addictions: uncovering the genes. Nat Rev Genet (2005) 5.05
A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94
Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America. Hum Mutat (2009) 4.65
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet (2004) 4.51
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. Alcohol Res Health (2007) 3.67
The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genet Epidemiol (2010) 3.48
Genome-wide association study of alcohol dependence. Arch Gen Psychiatry (2009) 3.08
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Nat Genet (2011) 3.06
Are there genetic influences on addiction: evidence from family, adoption and twin studies. Addiction (2008) 2.29
Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis. Hum Mol Genet (2008) 2.26
Collaborative genome-wide association studies of diverse diseases: programs of the NHGRI's office of population genomics. Pharmacogenomics (2009) 2.23
Replication in genome-wide association studies. Stat Sci (2009) 1.89
New insights into the genetics of addiction. Nat Rev Genet (2009) 1.70
Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology (2011) 1.50
Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample. Alcohol Clin Exp Res (2008) 1.41
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. Addict Biol (2011) 1.37
Self-reported ethnicity, genetic structure and the impact of population stratification in a multiethnic study. Hum Genet (2010) 1.26
Genetic variation within the anticoagulant, procoagulant, fibrinolytic and innate immunity pathways as risk factors for venous thromboembolism. J Thromb Haemost (2011) 1.19
Genome-wide association studies of alcohol dependence and substance use disorders. Curr Psychiatry Rep (2011) 1.11
Alcoholism and alcohol drinking habits predicted from alcohol dehydrogenase genes. Pharmacogenomics J (2007) 1.11
Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry. Alcohol Clin Exp Res (2009) 1.03
Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a Native American community sample. Alcohol Clin Exp Res (2011) 0.95
Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine. Eur J Neurol (2013) 0.93
Interaction of SLC6A4 and DRD2 polymorphisms is associated with a history of delirium tremens. Addict Biol (2010) 0.88
Variability in ethanol biodisposition in whites is modulated by polymorphisms in the ADH1B and ADH1C genes. Hepatology (2010) 0.82
Association of GATA4 sequence variation with alcohol dependence. Addict Biol (2012) 0.82
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest (2008) 16.17
Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest (2004) 11.84
Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet (2011) 8.57
Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2014) 6.55
Executive summary: heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2012) 6.24
Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2013) 6.13
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet (2008) 6.10
Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol (2002) 5.91
Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Third Edition). Reg Anesth Pain Med (2010) 4.77
Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study. Lancet (2010) 4.75
The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat Genet (2002) 4.54
Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet (2010) 4.51
Patent foramen ovale: innocent or guilty? Evidence from a prospective population-based study. J Am Coll Cardiol (2005) 4.39
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet (2009) 4.38
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Screening for bipolar disorder in the community. J Clin Psychiatry (2003) 4.24
Free-flight odor tracking in Drosophila is consistent with an optimal intermittent scale-free search. PLoS One (2007) 4.16
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat Genet (2010) 3.86
Regional anesthesia in the anticoagulated patient: defining the risks (the second ASRA Consensus Conference on Neuraxial Anesthesia and Anticoagulation). Reg Anesth Pain Med (2003) 3.85
Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet (2012) 3.68
Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality. Thromb Haemost (2007) 3.67
Genetic variants and risk of lung cancer in never smokers: a genome-wide association study. Lancet Oncol (2010) 3.49
The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genet Epidemiol (2010) 3.48
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet (2013) 3.42
BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair. Cancer Res (2003) 3.39
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nat Genet (2011) 3.16
Nonparametric tests of association of multiple genes with human disease. Am J Hum Genet (2005) 2.87
Two common chromosome 8q24 variants are associated with increased risk for prostate cancer. Cancer Res (2007) 2.56
How common is attention-deficit/hyperactivity disorder? Incidence in a population-based birth cohort in Rochester, Minn. Arch Pediatr Adolesc Med (2002) 2.51
Caution on pedigree haplotype inference with software that assumes linkage equilibrium. Am J Hum Genet (2002) 2.51
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study. Lancet Oncol (2013) 2.48
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32. Nat Genet (2010) 2.37
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer (2009) 2.32
Comparison of microsatellites versus single-nucleotide polymorphisms in a genome linkage screen for prostate cancer-susceptibility Loci. Am J Hum Genet (2004) 2.31
Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma. Blood (2007) 2.31
Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers. Am J Psychiatry (2006) 2.29
The poor prognosis of childhood-onset bipolar disorder. J Pediatr (2007) 2.26
Concern Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. J Clin Invest (2012) 2.23
Crossmodal visual input for odor tracking during fly flight. Curr Biol (2008) 2.21
The noninferiority of the nonparticulate steroid dexamethasone vs the particulate steroids betamethasone and triamcinolone in lumbar transforaminal epidural steroid injections. Pain Med (2013) 2.17
Depression, apolipoprotein E genotype, and the incidence of mild cognitive impairment: a prospective cohort study. Arch Neurol (2006) 2.13
Validity of the mood disorder questionnaire: a general population study. Am J Psychiatry (2003) 2.10
The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. Clin Cancer Res (2011) 2.09
Efficacy and safety of adjunctive armodafinil in adults with major depressive episodes associated with bipolar I disorder: a randomized, double-blind, placebo-controlled, multicenter trial. J Clin Psychiatry (2014) 2.07
Estimated annual numbers of US acute-care hospital patients at risk for venous thromboembolism. Am J Hematol (2007) 2.06
Inpatient medical-surgical suicidal behavior: a 12-year case-control study. Gen Hosp Psychiatry (2013) 2.01
Lack of differential motor outcome with subthalamic nucleus region stimulation in Parkinson's disease. J Clin Neurosci (2013) 1.99
The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry (2013) 1.97
Periprocedural anticoagulation management of patients with nonvalvular atrial fibrillation. Mayo Clin Proc (2008) 1.97
A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. Am J Hum Genet (2005) 1.96
Mutations in CHEK2 associated with prostate cancer risk. Am J Hum Genet (2003) 1.96
hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling. Gastroenterology (2004) 1.95
Impact of bipolar disorder on a U.S. community sample. J Clin Psychiatry (2003) 1.93
Early physical and sexual abuse associated with an adverse course of bipolar illness. Biol Psychiatry (2002) 1.93
Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Cancer Res (2007) 1.92
Telling the patient's story: using theatre training to improve case presentation skills. Med Humanit (2011) 1.92
Increased risk of monoclonal gammopathy in first-degree relatives of patients with multiple myeloma or monoclonal gammopathy of undetermined significance. Blood (2009) 1.90
Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up. Am J Psychiatry (2003) 1.88
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. Nat Genet (2013) 1.85
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res (2009) 1.83
Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL. Blood (2010) 1.79
Prevention of venous thromboembolism. Chest (2005) 1.76
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat Commun (2013) 1.73
Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart method. J Clin Psychiatry (2003) 1.72
miRNA expression in colon polyps provides evidence for a multihit model of colon cancer. PLoS One (2011) 1.72
Correlates of overweight and obesity in 644 patients with bipolar disorder. J Clin Psychiatry (2002) 1.71
Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics. Hum Genet (2006) 1.70
Gene networks and microRNAs implicated in aggressive prostate cancer. Cancer Res (2009) 1.68
Training in psychiatric genomics during residency: a new challenge. Acad Psychiatry (2010) 1.67
LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer. Cancer Res (2011) 1.64
Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels. Mayo Clin Proc (2011) 1.62
ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas. Gynecol Oncol (2013) 1.61
Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. J Clin Psychiatry (2002) 1.59
Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. Cancer Res (2009) 1.59
Spatial organization of visuomotor reflexes in Drosophila. J Exp Biol (2004) 1.59
Methodology for isolation, identification and characterization of microvesicles in peripheral blood. J Immunol Methods (2011) 1.58
Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury. J Clin Invest (2004) 1.58
Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study. J Clin Psychiatry (2009) 1.55
Surveillance for deep vein thrombosis and pulmonary embolism: recommendations from a national workshop. Am J Prev Med (2010) 1.55
Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood. J Clin Psychiatry (2010) 1.51
The presence of tandem endothelial nitric oxide synthase gene polymorphisms identifying brain aneurysms more prone to rupture. J Neurosurg (2005) 1.49
Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk. Cancer Res (2008) 1.49
High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure. Biol Psychiatry (2002) 1.48
Mitochondrial genetic polymorphisms and pancreatic cancer risk. Cancer Epidemiol Biomarkers Prev (2007) 1.48
Relationship between criminal arrest and community treatment history among patients with bipolar disorder. Psychiatr Serv (2005) 1.48
Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia. Am J Obstet Gynecol (2011) 1.47
Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". PLoS Genet (2010) 1.47
Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder. Bipolar Disord (2007) 1.46
Impact of depressive symptoms compared with manic symptoms in bipolar disorder: results of a U.S. community-based sample. J Clin Psychiatry (2004) 1.45
Characterization of blood borne microparticles as markers of premature coronary calcification in newly menopausal women. Am J Physiol Heart Circ Physiol (2008) 1.44
Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients. Am J Psychiatry (2005) 1.44
Peripheral visual circuits functionally segregate motion and phototaxis behaviors in the fly. Curr Biol (2009) 1.44
The potential role of fondaparinux as venous thromboembolism prophylaxis after total hip or knee replacement or hip fracture surgery. Arch Intern Med (2002) 1.44
Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network. J Clin Psychiatry (2003) 1.44
Nucleotide excision repair pathway polymorphisms and pancreatic cancer risk: evidence for role of MMS19L. Cancer Epidemiol Biomarkers Prev (2009) 1.43