Published in J Invest Dermatol on April 04, 2013
Basis for enhanced barrier function of pigmented skin. J Invest Dermatol (2014) 1.49
The role of AKT/mTOR pathway in stress response to UV-irradiation: implication in skin carcinogenesis by regulation of apoptosis, autophagy and senescence. Int J Mol Sci (2013) 1.04
Suppression of autophagy dysregulates the antioxidant response and causes premature senescence of melanocytes. J Invest Dermatol (2014) 0.92
ULK1 regulates melanin levels in MNT-1 cells independently of mTORC1. PLoS One (2013) 0.87
Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway. Sci Rep (2016) 0.82
Hyperosmotic stress reduces melanin production by altering melanosome formation. PLoS One (2014) 0.81
The signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases. Oncotarget (2016) 0.78
Cooperation of endothelin-1 signaling with melanosomes plays a role in developing and/or maintaining human skin hyperpigmentation. Biol Open (2015) 0.78
Dysfunction of Autophagy: A Possible Mechanism Involved in the Pathogenesis of Vitiligo by Breaking the Redox Balance of Melanocytes. Oxid Med Cell Longev (2016) 0.75
Identification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster. PLoS One (2015) 0.75
Bifunctional effects of O-methylated flavones from Scutellaria baicalensis Georgi on melanocytes: Inhibition of melanin production and intracellular melanosome transport. PLoS One (2017) 0.75
The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40
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In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell (2003) 17.55
How to interpret LC3 immunoblotting. Autophagy (2007) 12.30
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy (2007) 11.74
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature (2008) 11.39
Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol (2005) 10.27
Autophagy defends cells against invading group A Streptococcus. Science (2004) 9.53
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci (2004) 9.20
The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol (2011) 8.18
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation. Nat Cell Biol (2009) 7.84
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol (2009) 7.35
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell (2008) 6.66
Escape of intracellular Shigella from autophagy. Science (2004) 6.64
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci (2003) 6.50
Autophagosome formation in mammalian cells. Cell Struct Funct (2002) 5.58
Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole. J Biol Chem (2006) 5.50
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proc Natl Acad Sci U S A (2009) 4.48
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol (2007) 4.45
Autophagosomes form at ER-mitochondria contact sites. Nature (2013) 4.32
An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure. Mol Biol Cell (2008) 4.00
Autophagic control of listeria through intracellular innate immune recognition in drosophila. Nat Immunol (2008) 3.78
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem (2006) 3.77
The origin of the autophagosomal membrane. Nat Cell Biol (2010) 3.20
The autophagosome: origins unknown, biogenesis complex. Nat Rev Mol Cell Biol (2013) 3.04
Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J Cell Biol (2010) 2.98
Coronavirus replication complex formation utilizes components of cellular autophagy. J Biol Chem (2003) 2.96
A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery. Chem Biol (2011) 2.81
Intracellular inclusions containing mutant alpha1-antitrypsin Z are propagated in the absence of autophagic activity. J Biol Chem (2005) 2.60
Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes. Cell Struct Funct (2008) 2.47
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J Cell Sci (2004) 2.35
Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes. Mol Biol Cell (2005) 2.31
Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae. Proc Natl Acad Sci U S A (2007) 2.27
The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting. J Biol Chem (2003) 2.19
Listeria monocytogenes evades killing by autophagy during colonization of host cells. Autophagy (2007) 2.13
Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol Biol Cell (2008) 2.08
Monitoring autophagy in mammalian cultured cells through the dynamics of LC3. Methods Enzymol (2009) 1.99
Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action. Cell Host Microbe (2012) 1.99
Chemical modulators of autophagy as biological probes and potential therapeutics. Nat Chem Biol (2011) 1.97
ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy. Autophagy (2006) 1.97
GFP-like proteins stably accumulate in lysosomes. Cell Struct Funct (2008) 1.97
Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol Cell (2013) 1.95
The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella. Mol Biol Cell (2011) 1.79
Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy. Traffic (2010) 1.59
SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation. Cell Struct Funct (2002) 1.58
Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Am J Clin Nutr (2005) 1.58
Autophagy guards against cisplatin-induced acute kidney injury. Am J Pathol (2012) 1.56
Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection. Mol Biol Cell (2009) 1.55
Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes. Mol Biol Cell (2010) 1.55
A dominant negative form of the AAA ATPase SKD1/VPS4 impairs membrane trafficking out of endosomal/lysosomal compartments: class E vps phenotype in mammalian cells. J Cell Sci (2003) 1.52
A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring) (2007) 1.50
Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast. J Biol Chem (2005) 1.46
Effect of Helicobacter pylori's vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells. Autophagy (2009) 1.45
Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin. J Cell Biol (2013) 1.44
Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma. Int J Cancer (2011) 1.43
An initial step of GAS-containing autophagosome-like vacuoles formation requires Rab7. PLoS Pathog (2009) 1.43
Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin. J Biol Chem (2003) 1.37
Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts. J Biol Chem (2009) 1.36
Autophagy in innate immunity against intracellular bacteria. J Biochem (2006) 1.35
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation. Mol Biol Cell (2008) 1.34
Where do they come from? Insights into autophagosome formation. FEBS Lett (2010) 1.32
Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury. EMBO J (2013) 1.31
Green tea extract improves running endurance in mice by stimulating lipid utilization during exercise. Am J Physiol Regul Integr Comp Physiol (2006) 1.28
Virulence of Porphyromonas gingivalis is altered by substitution of fimbria gene with different genotype. Cell Microbiol (2006) 1.28
Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B. J Cell Sci (2004) 1.27
CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. J Cell Biol (2006) 1.25
The first molecular evidence that autophagy relates rimmed vacuole formation in chloroquine myopathy. J Biochem (2002) 1.24
Characterization of overall ceramide species in human stratum corneum. J Lipid Res (2008) 1.23
Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method. FEBS Lett (2002) 1.22
Coffee polyphenols suppress diet-induced body fat accumulation by downregulating SREBP-1c and related molecules in C57BL/6J mice. Am J Physiol Endocrinol Metab (2010) 1.20
Parental angst making and revisiting decisions about treatment of attention-deficit/hyperactivity disorder. Pediatrics (2009) 1.20
Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy. J Clin Invest (2014) 1.19
Regulation of membrane biogenesis in autophagy via PI3P dynamics. Semin Cell Dev Biol (2010) 1.19
Autophagosomes can support Yersinia pseudotuberculosis replication in macrophages. Cell Microbiol (2010) 1.16
Role of Hrs in maturation of autophagosomes in mammalian cells. Biochem Biophys Res Commun (2007) 1.16
The C/EBP beta isoform 34-kDa LAP is responsible for NF-IL-6-mediated gene induction in activated macrophages, but is not essential for intracellular bacteria killing. J Immunol (2007) 1.16
Up-to-date membrane biogenesis in the autophagosome formation. Curr Opin Cell Biol (2013) 1.15
Porphyromonas gingivalis outer membrane vesicles enter human epithelial cells via an endocytic pathway and are sorted to lysosomal compartments. Infect Immun (2009) 1.15
Role of the Apg12 conjugation system in mammalian autophagy. Int J Biochem Cell Biol (2003) 1.15
Ubiquitination-mediated autophagy against invading bacteria. Curr Opin Cell Biol (2011) 1.13
Dietary fish oil upregulates intestinal lipid metabolism and reduces body weight gain in C57BL/6J mice. J Nutr (2007) 1.13
Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation. Autophagy (2010) 1.13
Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice. Biogerontology (2008) 1.12
Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. Gastroenterology (2012) 1.12
Biphasic expression of two paracrine melanogenic cytokines, stem cell factor and endothelin-1, in ultraviolet B-induced human melanogenesis. Am J Pathol (2004) 1.11
Changes in the ceramide profile of atopic dermatitis patients. J Invest Dermatol (2010) 1.10
Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain. Mol Biol Cell (2010) 1.10
A catechin-rich beverage improves obesity and blood glucose control in patients with type 2 diabetes. Obesity (Silver Spring) (2008) 1.10
Ferulic acid restores endothelium-dependent vasodilation in aortas of spontaneously hypertensive rats. Am J Hypertens (2007) 1.09
Molecular basis of canonical and bactericidal autophagy. Int Immunol (2009) 1.09
Survival of parvovirus B19-infected cells by cellular autophagy. Virology (2006) 1.08
Artificial induction of autophagy around polystyrene beads in nonphagocytic cells. Autophagy (2010) 1.06
Biomarkers of epidermal innate immunity in premature and full-term infants. Pediatr Res (2010) 1.04
Effect of dermal thickness, tissue composition, and body site on skin biomechanical properties. Skin Res Technol (2006) 1.03
Bornavirus closely associates and segregates with host chromosomes to ensure persistent intranuclear infection. Cell Host Microbe (2012) 1.03