Published in EMBO J on April 09, 2013
Cell biology in neuroscience: Cellular and molecular mechanisms underlying axon formation, growth, and branching. J Cell Biol (2013) 1.12
Human CFEOM1 mutations attenuate KIF21A autoinhibition and cause oculomotor axon stalling. Neuron (2014) 1.05
prickle modulates microtubule polarity and axonal transport to ameliorate seizures in flies. Proc Natl Acad Sci U S A (2014) 0.99
The axonal cytoskeleton: from organization to function. Front Mol Neurosci (2015) 0.96
Cytoskeletal social networking in the growth cone: How +TIPs mediate microtubule-actin cross-linking to drive axon outgrowth and guidance. Cytoskeleton (Hoboken) (2016) 0.88
TIPsy tour guides: how microtubule plus-end tracking proteins (+TIPs) facilitate axon guidance. Front Cell Neurosci (2015) 0.87
CaV2.2 channel cell surface expression is regulated by the light chain 1 (LC1) of the microtubule-associated protein B (MAP1B) via UBE2L3-mediated ubiquitination and degradation. Pflugers Arch (2014) 0.87
Microtubules in neurons as information carriers. J Neurochem (2013) 0.85
Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2. BMC Biol (2014) 0.84
The cytoskeleton and neurite initiation. Bioarchitecture (2014) 0.83
Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system. Mol Biol Cell (2015) 0.82
Neurodegeneration and microtubule dynamics: death by a thousand cuts. Front Cell Neurosci (2015) 0.82
Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites. EMBO J (2016) 0.82
Building Blocks of Functioning Brain: Cytoskeletal Dynamics in Neuronal Development. Int Rev Cell Mol Biol (2016) 0.80
Regulation of EB1/3 proteins by classical MAPs in neurons. Bioarchitecture (2014) 0.79
Regulation of microtubule-based transport by MAP4. Mol Biol Cell (2014) 0.78
Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity. Neural Plast (2016) 0.78
Microtubule plus-end tracking proteins in neuronal development. Cell Mol Life Sci (2016) 0.77
Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3. Oncotarget (2015) 0.77
Repulsive axon guidance by Draxin is mediated by protein Kinase B (Akt), glycogen synthase kinase-3β (GSK-3β) and microtubule-associated protein 1B. PLoS One (2015) 0.76
A conceptual view at microtubule plus end dynamics in neuronal axons. Brain Res Bull (2016) 0.76
Microtubule Plus-end Tracking of End-binding Protein 1 (EB1) Is Regulated by CDK5 Regulatory Subunit-associated Protein 2. J Biol Chem (2017) 0.75
A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease. Front Cell Neurosci (2016) 0.75
Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation-dependent mechanism. Mol Biol Cell (2016) 0.75
Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev (2016) 0.75
ADNP/NAP dramatically increase microtubule end-binding protein-Tau interaction: a novel avenue for protection against tauopathy. Mol Psychiatry (2017) 0.75
The calcium-binding protein ALG-2 regulates protein secretion and trafficking via interactions with MISSL and MAP1B. J Biol Chem (2017) 0.75
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene (1988) 52.71
Tracking the ends: a dynamic protein network controls the fate of microtubule tips. Nat Rev Mol Cell Biol (2008) 7.15
Rat hippocampal neurons in dispersed cell culture. Brain Res (1977) 5.29
Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). J Neurosci (2003) 4.72
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron (2009) 3.54
Reconstitution of a microtubule plus-end tracking system in vitro. Nature (2007) 3.50
Mammalian end binding proteins control persistent microtubule growth. J Cell Biol (2009) 2.82
EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle. Oncogene (1998) 2.65
Increased microtubule stability and alpha tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or tau. J Cell Sci (1992) 2.42
CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites. J Cell Biol (2008) 2.31
EBs recognize a nucleotide-dependent structural cap at growing microtubule ends. Cell (2012) 2.24
Microtubule plus end: a hub of cellular activities. Traffic (2006) 2.21
EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Mol Biol Cell (2005) 2.19
Microtubule plus-end tracking by CLIP-170 requires EB1. Proc Natl Acad Sci U S A (2009) 2.15
Glycogen synthase kinase 3beta phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones. J Cell Sci (1999) 2.10
GTPgammaS microtubules mimic the growing microtubule end structure recognized by end-binding proteins (EBs). Proc Natl Acad Sci U S A (2011) 1.79
Plus-end-tracking proteins and their interactions at microtubule ends. Curr Biol (2010) 1.78
Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis. Nat Cell Biol (2008) 1.70
Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends. J Cell Biol (2008) 1.68
Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p. J Cell Biol (2009) 1.68
Cytoplasmic dynein and LIS1 are required for microtubule advance during growth cone remodeling and fast axonal outgrowth. J Neurosci (2007) 1.67
Microtubules and maps. Adv Protein Chem (2005) 1.60
Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain. J Cell Biol (1998) 1.47
Structural and mechanistic insights into microtubule end-binding proteins. Curr Opin Cell Biol (2009) 1.42
EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue. Oncogene (2000) 1.37
Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells. EMBO J (1993) 1.31
Neuronal microtubule-associated proteins in the embryonic avian spinal cord. J Comp Neurol (1988) 1.21
Evidence for the role of MAP1B in axon formation. Mol Biol Cell (2001) 1.20
In situ localization of microtubule-associated protein mRNA in the developing and adult rat brain. Neuron (1989) 1.18
MAP1B regulates axonal development by modulating Rho-GTPase Rac1 activity. Mol Biol Cell (2010) 1.17
NMDA receptor activation suppresses microtubule growth and spine entry. J Neurosci (2011) 1.17
Effect of GFP tags on the localization of EB1 and EB1 fragments in vivo. Cytoskeleton (Hoboken) (2010) 1.15
Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels. Mol Cell Neurosci (2000) 1.13
Microtubule-associated protein 1b (MAP1b) is concentrated in the distal region of growing axons. J Neurosci (1994) 1.13
Cytoplasmic linker proteins regulate neuronal polarization through microtubule and growth cone dynamics. J Neurosci (2011) 1.09
Microtubule-associated protein 1B function during normal development, regeneration, and pathological conditions in the nervous system. J Neurobiol (2004) 1.09
End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment. Proc Natl Acad Sci U S A (2011) 1.08
Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits. Neurobiol Dis (2009) 1.06
History-dependent catastrophes regulate axonal microtubule behavior. Curr Biol (2010) 1.05
MAP1B enhances microtubule assembly rates and axon extension rates in developing neurons. Mol Cell Neurosci (2011) 1.01
Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons. Brain Res (2002) 1.00
Differences in the regulation of microtubule dynamics by microtubule-associated proteins MAP1B and MAP2. Cell Motil Cytoskeleton (1996) 0.94
Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1. Biochem J (2005) 0.89
Implication of cyclin-dependent kinases and glycogen synthase kinase 3 in the phosphorylation of microtubule-associated protein 1B in developing neuronal cells. J Neurosci Res (1998) 0.86
Cloning of a cDNA encoding MAP1B in rat brain: regulation of mRNA levels during development. J Neurochem (1989) 0.82
Microtubule associated protein 1B (MAP1B) promotes efficient tubulin polymerisation in vitro. FEBS Lett (1995) 0.81
CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev (2006) 6.32
Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). J Neurosci (2003) 4.72
Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network. Dev Cell (2007) 4.17
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature (2010) 4.16
CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol (2005) 3.54
CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta. Dev Cell (2006) 2.99
Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nat Cell Biol (2002) 2.75
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem (2003) 2.65
LIS1, CLIP-170's key to the dynein/dynactin pathway. Mol Cell Biol (2002) 2.61
Cytoplasmic linker proteins promote microtubule rescue in vivo. J Cell Biol (2002) 2.38
Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends. J Cell Biol (2006) 2.25
Inhibition of glycogen synthase kinase 3beta during heart failure is protective. Circ Res (2007) 2.22
Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules. Blood (2008) 2.20
EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Mol Biol Cell (2005) 2.19
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. J Cell Biol (2004) 2.12
Particle filtering for multiple object tracking in dynamic fluorescence microscopy images: application to microtubule growth analysis. IEEE Trans Med Imaging (2008) 2.03
Glycogen synthase kinase 3: a drug target for CNS therapies. J Neurochem (2004) 1.97
Neuronal induction of the immunoproteasome in Huntington's disease. J Neurosci (2003) 1.83
Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly. EMBO J (2008) 1.81
Role of CLASP2 in microtubule stabilization and the regulation of persistent motility. Curr Biol (2006) 1.81
Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice. Nat Genet (2002) 1.81
CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin. EMBO J (2005) 1.81
Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood (2005) 1.76
Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends. J Cell Biol (2008) 1.68
Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. EMBO J (2003) 1.65
Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis. Mol Cell Biol (2006) 1.63
The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus. Immunity (2011) 1.57
CTCF regulates cell cycle progression of alphabeta T cells in the thymus. EMBO J (2008) 1.55
Glycogen synthase kinase-3 inhibition is integral to long-term potentiation. Eur J Neurosci (2007) 1.50
CLIP-170 facilitates the formation of kinetochore-microtubule attachments. EMBO J (2005) 1.47
Extracellular tau is toxic to neuronal cells. FEBS Lett (2006) 1.47
Phosphorylation of CLASP2 by GSK-3beta regulates its interaction with IQGAP1, EB1 and microtubules. J Cell Sci (2009) 1.46
Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. J Neurosci (2006) 1.44
Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments. J Neurochem (2002) 1.42
Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway. J Cell Sci (2008) 1.39
Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux. Curr Biol (2009) 1.34
Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert. J Neurochem (2006) 1.34
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med (2002) 1.34
The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis. Genes Dev (2005) 1.33
Functional analysis of CTCF during mammalian limb development. Dev Cell (2010) 1.33
GSK3: a possible link between beta amyloid peptide and tau protein. Exp Neurol (2009) 1.32
Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease. J Alzheimers Dis (2009) 1.29
Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model. J Alzheimers Dis (2003) 1.29
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. Mol Biol Cell (2006) 1.29
CTCF is required for neural development and stochastic expression of clustered Pcdh genes in neurons. Cell Rep (2012) 1.27
Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function. Mol Biol Cell (2006) 1.26
Differential effects of matrix and growth factors on endothelial and fibroblast motility: application of a modified cell migration assay. J Cell Biochem (2006) 1.20
Microtubule-binding proteins CLASP1 and CLASP2 interact with actin filaments. Cell Motil Cytoskeleton (2007) 1.19
Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35. Implications for Alzheimer's disease. J Biol Chem (2003) 1.19
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles. FEBS Lett (2011) 1.17
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models. Neurobiol Dis (2005) 1.16
Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau. J Biol Chem (2010) 1.15
N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation. J Biol Chem (2007) 1.15
Critical role for the transcription regulator CCCTC-binding factor in the control of Th2 cytokine expression. J Immunol (2009) 1.14
A role of MAP1B in Reelin-dependent neuronal migration. Cereb Cortex (2004) 1.13
Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice. Neurobiol Dis (2005) 1.11
LIMK1 and CLIP-115: linking cytoskeletal defects to Williams syndrome. Bioessays (2004) 1.11
Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3. Biochem J (2003) 1.11
Regulation of GSK3 isoforms by phosphatases PP1 and PP2A. Mol Cell Biochem (2010) 1.08
Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits. Neurobiol Dis (2009) 1.06
CTCF regulates the local epigenetic state of ribosomal DNA repeats. Epigenetics Chromatin (2010) 1.06
Cooexpression of FTDP-17 tau and GSK-3beta in transgenic mice induce tau polymerization and neurodegeneration. Neurobiol Aging (2005) 1.05
Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub. Proc Natl Acad Sci U S A (2012) 1.05
History-dependent catastrophes regulate axonal microtubule behavior. Curr Biol (2010) 1.05
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. Int J Exp Pathol (2008) 1.04
Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain. J Neurosci (2004) 1.04
Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice. EMBO J (2007) 1.04
Glycogen synthase kinase-3 (GSK-3) inhibitors for the treatment of Alzheimer's disease. Curr Pharm Des (2010) 1.04
A new mutation of the tau gene, G303V, in early-onset familial progressive supranuclear palsy. Arch Neurol (2005) 1.04
MAP1B is required for Netrin 1 signaling in neuronal migration and axonal guidance. Curr Biol (2004) 1.04
Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions. Cell Motil Cytoskeleton (2009) 1.03
Glycogen synthase kinase-3 is activated in neuronal cells by Galpha12 and Galpha13 by Rho-independent and Rho-dependent mechanisms. J Neurosci (2002) 1.03
Creating a transatlantic research enterprise for preventing Alzheimer's disease. Alzheimers Dement (2009) 1.02
Chronological primacy of oxidative stress in Alzheimer disease. Neurobiol Aging (2005) 1.02
Rao-Blackwellized marginal particle filtering for multiple object tracking in molecular bioimaging. Inf Process Med Imaging (2007) 1.01
The role of GSK3 in Alzheimer disease. Brain Res Bull (2009) 1.00
Deconstructing mitochondrial dysfunction in Alzheimer disease. Oxid Med Cell Longev (2013) 0.99
The influence of phospho-τ on dendritic spines of cortical pyramidal neurons in patients with Alzheimer's disease. Brain (2013) 0.99
Cryo electron tomography of vitrified fibroblasts: microtubule plus ends in situ. J Struct Biol (2007) 0.99
GSK3β overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrus. Hippocampus (2010) 0.99
Estradiol prevents neural tau hyperphosphorylation characteristic of Alzheimer's disease. Ann N Y Acad Sci (2005) 0.99
Alpha-helix structure in Alzheimer's disease aggregates of tau-protein. Biochemistry (2002) 0.98
The role of glycogen synthase kinase 3 in the early stages of Alzheimers' disease. FEBS Lett (2008) 0.98
Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord (2002) 0.98
GSK3 inhibitors and disease. Mini Rev Med Chem (2009) 0.98
Role of MAP1B in axonal retrograde transport of mitochondria. Biochem J (2006) 0.97
Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and β-Amyloid. Front Mol Neurosci (2011) 0.97
The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. Epigenetics Chromatin (2012) 0.97
Formation of aberrant phosphotau fibrillar polymers in neural cultured cells. Eur J Biochem (2002) 0.96
Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation. J Biol Chem (2011) 0.95
Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells. J Neurosci Res (2003) 0.95
Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation. Toxicol Sci (2011) 0.94
Agrin regulates CLASP2-mediated capture of microtubules at the neuromuscular junction synaptic membrane. J Cell Biol (2012) 0.94
Tau overexpression results in its secretion via membrane vesicles. Neurodegener Dis (2012) 0.94
Glycosaminoglycans and beta-amyloid, prion and tau peptides in neurodegenerative diseases. Peptides (2002) 0.94
Phosphorylation controls autoinhibition of cytoplasmic linker protein-170. Mol Biol Cell (2010) 0.93
Three-dimensional structure of human tubulin chaperone cofactor A. J Mol Biol (2002) 0.92
Glycogen Synthase Kinase-3 Modulates Neurite Outgrowth in Cultured Neurons: Possible Implications for Neurite Pathology in Alzheimer's Disease. J Alzheimers Dis (1999) 0.92
GSK-3 dependent phosphoepitopes recognized by PHF-1 and AT-8 antibodies are present in different tau isoforms. Neurobiol Aging (2003) 0.91