Published in Oxid Med Cell Longev on June 11, 2013
Mitochondrial dysfunctions in neurodegenerative diseases: relevance to Alzheimer's disease. Biomed Res Int (2014) 1.01
Mevalonate kinase deficiency and neuroinflammation: balance between apoptosis and pyroptosis. Int J Mol Sci (2013) 1.00
An oxidative stress mechanism of shikonin in human glioma cells. PLoS One (2014) 0.93
Oxidant/Antioxidant imbalance and the risk of Alzheimer's disease. Curr Alzheimer Res (2015) 0.92
Signaling pathway cross talk in Alzheimer's disease. Cell Commun Signal (2014) 0.89
Amyloid-beta neuroprotection mediated by a targeted antioxidant. Sci Rep (2014) 0.81
Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress. Brain Res (2016) 0.81
Role of Notch-1 signaling pathway in PC12 cell apoptosis induced by amyloid beta-peptide (25-35). Neural Regen Res (2014) 0.79
A platform for high-throughput bioenergy production phenotype characterization in single cells. Sci Rep (2017) 0.77
S-nitrosylation of the thioredoxin-like domains of protein disulfide isomerase and its role in neurodegenerative conditions. Front Chem (2015) 0.77
The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease. Oxid Med Cell Longev (2015) 0.77
Effects of Copper and/or Cholesterol Overload on Mitochondrial Function in a Rat Model of Incipient Neurodegeneration. Int J Alzheimers Dis (2013) 0.76
PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Hum Mol Genet (2015) 0.76
Loss of forebrain MTCH2 decreases mitochondria motility and calcium handling and impairs hippocampal-dependent cognitive functions. Sci Rep (2017) 0.75
A Search for Mitochondrial Damage in Alzheimer's Disease Using Isolated Rat Brain Mitochondria. Iran J Pharm Res (2016) 0.75
Intermittent hypoxia training protects cerebrovascular function in Alzheimer's disease. Exp Biol Med (Maywood) (2016) 0.75
Outlining Core Pathways of Amyloid Toxicity in Bacteria with the RepA-WH1 Prionoid. Front Microbiol (2017) 0.75
Amyloid-β-Induced Changes in Molecular Clock Properties and Cellular Bioenergetics. Front Neurosci (2017) 0.75
Transcription factors CEP-1/p53 and CEH-23 collaborate with AAK-2/AMPK to modulate longevity in Caenorhabditis elegans. Aging Cell (2017) 0.75
Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Free Radic Biol Med (2017) 0.75
Genetic Analysis of Mitochondrial Ribosomal Proteins and Cognitive Aging in Postmenopausal Women. Front Genet (2017) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol (2004) 21.56
Direct conversion of fibroblasts to functional neurons by defined factors. Nature (2010) 18.76
Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci U S A (1985) 16.10
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol (2010) 12.26
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol (2010) 11.85
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol (2008) 10.97
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol Biol Cell (2001) 9.67
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell (2009) 8.62
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. J Biol Chem (1986) 6.91
Induction of human neuronal cells by defined transcription factors. Nature (2011) 6.84
Age, neuropathology, and dementia. N Engl J Med (2009) 6.36
Functions and dysfunctions of mitochondrial dynamics. Nat Rev Mol Cell Biol (2007) 6.33
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J Neuropathol Exp Neurol (2005) 6.16
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell (2011) 6.11
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. J Biol Chem (2007) 5.95
Intracellular amyloid-beta in Alzheimer's disease. Nat Rev Neurosci (2007) 5.72
MicroRNA-mediated conversion of human fibroblasts to neurons. Nature (2011) 5.59
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature (2012) 5.47
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J Biol Chem (2004) 5.14
Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat Biotechnol (2009) 5.14
Retracted Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons. Cell (2011) 5.09
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell (2010) 5.09
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science (2004) 4.81
A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell (2009) 4.64
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. Science (2009) 4.25
Targeting antioxidants to mitochondria by conjugation to lipophilic cations. Annu Rev Pharmacol Toxicol (2007) 4.16
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest (2008) 4.09
Direct reprogramming of mouse fibroblasts to neural progenitors. Proc Natl Acad Sci U S A (2011) 3.93
Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. J Cell Biol (2010) 3.91
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. J Cell Biol (2007) 3.83
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci (2009) 3.77
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet (2010) 3.77
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med (2008) 3.69
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci U S A (2008) 3.68
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease. PLoS One (2010) 3.62
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell (2011) 3.62
Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell (2012) 3.52
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci U S A (2012) 3.52
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol (2002) 3.35
Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. J Biol Chem (2010) 3.16
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction. J Neurosci (2006) 3.00
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease. FASEB J (2005) 2.91
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits. Brain (2011) 2.76
Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission. EMBO J (2011) 2.71
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. J Neurosci (2010) 2.55
Regulation of somatic cell reprogramming through inducible mir-302 expression. Nucleic Acids Res (2010) 2.40
Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles. J Cell Sci (1999) 2.36
Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum Mol Genet (2011) 2.26
Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons. J Neurosci (2006) 2.10
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients. Am J Pathol (2008) 2.09
Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Res (2010) 2.04
Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proc Natl Acad Sci U S A (2009) 2.04
Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review. Free Radic Res (2002) 1.97
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. Hum Mol Genet (2011) 1.96
Alzheimer's disease: genetic studies and transgenic models. Annu Rev Genet (1998) 1.93
Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons. J Alzheimers Dis (2010) 1.84
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease. Hum Mol Genet (2011) 1.75
Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease. Int J Biochem Cell Biol (2004) 1.74
Targeting antioxidants to mitochondria: a new therapeutic direction. Biochim Biophys Acta (2005) 1.68
18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease. Brain (2011) 1.67
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta (2009) 1.66
Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J (2006) 1.65
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem (2005) 1.64
Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice. Neurobiol Aging (2008) 1.59
Tau promotes neurodegeneration via DRP1 mislocalization in vivo. Neuron (2012) 1.58
Mitochondrial oxidative stress causes hyperphosphorylation of tau. PLoS One (2007) 1.55
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy. Brain (2012) 1.55
Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways. J Neurochem (2005) 1.53
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease. EMBO J (2012) 1.53
Aging sensitizes toward ROS formation and lipid peroxidation in PS1M146L transgenic mice. Free Radic Biol Med (2005) 1.51
Mitochondrial morphology and distribution in mammalian cells. Biol Chem (2006) 1.49
Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease. Arch Neurol (1988) 1.48
Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology (2010) 1.46
SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle. FASEB J (2009) 1.45
Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria. J Biol Chem (2004) 1.39
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics. Biochim Biophys Acta (2011) 1.32
Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment. Exp Neurol (2003) 1.30
Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain. Am J Pathol (2011) 1.30
Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons. Neurodegener Dis (2010) 1.27
S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease. J Alzheimers Dis (2010) 1.26
The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease. J Neurosci (2011) 1.26
Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension. Hum Mol Genet (2012) 1.22
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis (2007) 1.19
Parkin promotes intracellular Abeta1-42 clearance. Hum Mol Genet (2009) 1.18
Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons. J Neurosci (2007) 1.18
Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol (2007) 1.18
Amyloid-Beta interaction with mitochondria. Int J Alzheimers Dis (2011) 1.18
Convergence of amyloid-beta and tau pathologies on mitochondria in vivo. Mol Neurobiol (2010) 1.16
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. J Neurochem (2003) 1.14
Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy (2007) 1.14
Mitochondrial respiratory inhibition and oxidative stress elevate beta-secretase (BACE1) proteins and activity in vivo in the rat retina. Exp Brain Res (2007) 1.12
Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models. Hum Mol Genet (2011) 1.12
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation. Antioxid Redox Signal (2012) 1.12
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis (2013) 1.11
Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury. J Neurochem (2004) 1.10
Coenzyme A-acetylating enzymes in Alzheimer's disease: possible cholinergic 'compartment' of pyruvate dehydrogenase. Neurosci Lett (1980) 1.06
Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease. Hum Mol Genet (2012) 1.04
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci (2009) 3.77
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem (2003) 2.65
Inhibition of glycogen synthase kinase 3beta during heart failure is protective. Circ Res (2007) 2.22
Oxidative stress and neurotoxicity. Chem Res Toxicol (2007) 2.12
Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta. Brain Res Brain Res Rev (2003) 1.97
Glycogen synthase kinase 3: a drug target for CNS therapies. J Neurochem (2004) 1.97
Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol (2006) 1.92
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence. Biochemistry (2003) 1.89
Oxidative stress increases expression and activity of BACE in NT2 neurons. Neurobiol Dis (2002) 1.85
Neuronal induction of the immunoproteasome in Huntington's disease. J Neurosci (2003) 1.83
Alzheimer's disease: the two-hit hypothesis. Lancet Neurol (2004) 1.81
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem (2009) 1.67
Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Ann Neurol (2010) 1.66
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta (2009) 1.66
Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. Am J Pathol (2003) 1.66
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem (2005) 1.61
Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem (2007) 1.61
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J Neurochem (2011) 1.57
The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals (2003) 1.56
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum Mol Genet (2012) 1.56
Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta (2006) 1.56
A new model of oxidative stress in rat pups. Neonatology (2008) 1.55
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis (2010) 1.54
Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res (2005) 1.51
Glycogen synthase kinase-3 inhibition is integral to long-term potentiation. Eur J Neurosci (2007) 1.50
Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim Biophys Acta (2009) 1.49
Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Ann N Y Acad Sci (2004) 1.49
Extracellular tau is toxic to neuronal cells. FEBS Lett (2006) 1.47
Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins. FASEB J (2002) 1.47
4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chem Res Toxicol (2005) 1.46
Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology (2010) 1.46
Nucleic acid oxidation in Alzheimer disease. Free Radic Biol Med (2008) 1.45
Alzheimer disease pathology as a host response. J Neuropathol Exp Neurol (2008) 1.45
Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. J Neurosci (2006) 1.44
Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice. J Nucl Med (2002) 1.44
The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem (2009) 1.43
Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments. J Neurochem (2002) 1.42
Leptin: a novel therapeutic strategy for Alzheimer's disease. J Alzheimers Dis (2009) 1.42
The end of a Chilean institute. Science (2005) 1.39
Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death. Hum Mol Genet (2011) 1.38
Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage. Invest Ophthalmol Vis Sci (2007) 1.37
Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res (2002) 1.37
Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert. J Neurochem (2006) 1.34
Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiol Dis (2002) 1.34
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med (2002) 1.34
Oxidative stress signalling in Alzheimer's disease. Brain Res (2004) 1.33
Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol (2006) 1.33
GSK3: a possible link between beta amyloid peptide and tau protein. Exp Neurol (2009) 1.32
Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry (2004) 1.30
Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults. J Alzheimers Dis (2012) 1.30
The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease. Brain Pathol (2002) 1.29
Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease. J Alzheimers Dis (2009) 1.29
Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model. J Alzheimers Dis (2003) 1.29
Oxidative stress in diabetes and Alzheimer's disease. J Alzheimers Dis (2009) 1.29
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. Mol Biol Cell (2006) 1.29
Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons. Neurodegener Dis (2010) 1.27
Tau--an inhibitor of deacetylase HDAC6 function. J Neurochem (2009) 1.27
Alzheimer Disease and Oxidative Stress. J Biomed Biotechnol (2002) 1.26
Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice. Biochim Biophys Acta (2006) 1.26
Mitochondria: a therapeutic target in neurodegeneration. Biochim Biophys Acta (2009) 1.25
Vascular oxidative stress in Alzheimer disease. J Neurol Sci (2007) 1.25
Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? Acta Neuropathol (2003) 1.24
Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. J Pharmacol Exp Ther (2007) 1.23
AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation. Neurobiol Aging (2010) 1.21
Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. J Biol Chem (2004) 1.21
Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans. Neurosci Lett (2002) 1.20
Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. J Alzheimers Dis (2006) 1.20
Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends Mol Med (2005) 1.20
Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35. Implications for Alzheimer's disease. J Biol Chem (2003) 1.19
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis (2007) 1.19
Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol (2007) 1.18
Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochem Int (2008) 1.18
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles. FEBS Lett (2011) 1.17
Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotox Res (2012) 1.17
Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain. Free Radic Biol Med (2002) 1.17
Mitochondrial failures in Alzheimer's disease. Am J Alzheimers Dis Other Demen (2005) 1.17
LRRK2 protein is a component of Lewy bodies. Ann Neurol (2006) 1.16
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models. Neurobiol Dis (2005) 1.16
Current approaches in the treatment of Alzheimer's disease. Biomed Pharmacother (2008) 1.16
Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau. J Biol Chem (2010) 1.15
N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation. J Biol Chem (2007) 1.15
Oxidative stress and neurodegeneration. Ann N Y Acad Sci (2005) 1.15
Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord Drug Targets (2008) 1.15
RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol (2009) 1.15
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. J Neurochem (2003) 1.14
Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy (2007) 1.14
Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. J Alzheimers Dis (2009) 1.13
Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiol Dis (2004) 1.13
A role of MAP1B in Reelin-dependent neuronal migration. Cereb Cortex (2004) 1.13
Role of metal dyshomeostasis in Alzheimer's disease. Metallomics (2011) 1.12
Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice. Neurobiol Dis (2005) 1.11
Amyloid beta: the alternate hypothesis. Curr Alzheimer Res (2006) 1.11
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis (2013) 1.11
Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport (2002) 1.11
Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic Biol Med (2007) 1.11
Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3. Biochem J (2003) 1.11
Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides (2002) 1.10
DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell (2011) 1.09