Published in J Cell Sci on August 25, 2004
P2X7 receptor-Pannexin1 complex: pharmacology and signaling. Am J Physiol Cell Physiol (2008) 2.49
Connexins, pannexins, innexins: novel roles of "hemi-channels". Pflugers Arch (2008) 1.45
Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics. J Membr Biol (2007) 0.90
Technical Advance: The rat aorta contains resident mononuclear phagocytes with proliferative capacity and proangiogenic properties. J Leukoc Biol (2010) 0.90
C terminus of the P2X7 receptor: treasure hunting. Purinergic Signal (2011) 0.89
Interaction of P2 purinergic receptors with cellular macromolecules. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.86
Regulation of hemichannels and gap junction channels by cytokines in antigen-presenting cells. Mediators Inflamm (2014) 0.83
Connexin and pannexin (hemi)channels in the liver. Front Physiol (2014) 0.83
Differential modulation of ATP-induced P2X7-associated permeabilities to cations and anions of macrophages by infection with Leishmania amazonensis. PLoS One (2011) 0.83
Involvement of connexin43 hemichannel in ATP release after γ-irradiation. J Radiat Res (2012) 0.79
Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone. Arterioscler Thromb Vasc Biol (2016) 0.77
Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins. Front Neurosci (2016) 0.75
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J Biol Chem (2006) 4.33
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett (2007) 3.19
P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J Neurosci (2006) 3.14
The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J Biol Chem (2009) 2.90
Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis. Curr Biol (2006) 2.86
Pannexin 1: the molecular substrate of astrocyte "hemichannels". J Neurosci (2009) 2.48
Pannexin channels are not gap junction hemichannels. Channels (Austin) (2011) 1.84
Mechanisms of glutamate release from astrocytes: gap junction "hemichannels", purinergic receptors and exocytotic release. Neurochem Int (2004) 1.53
Targeting pannexin1 improves seizure outcome. PLoS One (2011) 1.43
The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes. Glia (2005) 1.42
Safety of autologous bone marrow mononuclear cell transplantation in patients with nonacute ischemic stroke. Regen Med (2011) 1.28
Array analysis of gene expression in connexin-43 null astrocytes. Physiol Genomics (2003) 1.24
Distinct kinetics of effector CD8+ cytotoxic T cells after infection with Trypanosoma cruzi in naive or vaccinated mice. Infect Immun (2006) 1.22
ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes. Glia (2012) 1.22
Bone marrow multipotent mesenchymal stromal cells do not reduce fibrosis or improve function in a rat model of severe chronic liver injury. Stem Cells (2008) 1.21
Acute downregulation of Cx43 alters P2Y receptor expression levels in mouse spinal cord astrocytes. Glia (2003) 1.21
Exocytosis of ATP from astrocyte progenitors modulates spontaneous Ca2+ oscillations and cell migration. Glia (2007) 1.16
Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis. J Neurosci Res (2005) 1.14
Gene expression alterations in connexin null mice extend beyond the gap junction. Neurochem Int (2004) 1.12
Mefloquine blockade of Pannexin1 currents: resolution of a conflict. Cell Commun Adhes (2009) 1.12
Modulation of CD4(+) T cell-dependent specific cytotoxic CD8(+) T cells differentiation and proliferation by the timing of increase in the pathogen load. PLoS One (2007) 1.11
A comparative antibody analysis of pannexin1 expression in four rat brain regions reveals varying subcellular localizations. Front Pharmacol (2013) 1.09
Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation. Br J Pharmacol (2006) 1.08
Similar transcriptomic alterations in Cx43 knockdown and knockout astrocytes. Cell Commun Adhes (2008) 1.07
Trypanosoma cruzi induces edematogenic responses in mice and invades cardiomyocytes and endothelial cells in vitro by activating distinct kinin receptor (B1/B2) subtypes. FASEB J (2002) 1.06
Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages. Biochem Pharmacol (2005) 1.03
Activation of the P2X(7) receptor triggers the elimination of Toxoplasma gondii tachyzoites from infected macrophages. Microbes Infect (2010) 1.03
Migration and homing of bone-marrow mononuclear cells in chronic ischemic stroke after intra-arterial injection. Exp Neurol (2009) 1.03
Host-cell lipid rafts: a safe door for micro-organisms? Biol Cell (2010) 1.02
The TLR3 ligand polyI: C downregulates connexin 43 expression and function in astrocytes by a mechanism involving the NF-kappaB and PI3 kinase pathways. Glia (2006) 1.01
Two non-vesicular ATP release pathways in the mouse erythrocyte membrane. FEBS Lett (2011) 1.00
Pannexin 1 involvement in bladder dysfunction in a multiple sclerosis model. Sci Rep (2013) 0.98
Promises and pitfalls of a Pannexin1 transgenic mouse line. Front Pharmacol (2013) 0.97
Lipopolysaccharide-induced lung injury: role of P2X7 receptor. Respir Physiol Neurobiol (2011) 0.97
Extracellular ATP induces cell death in CD4+/CD8+ double-positive thymocytes in mice infected with Trypanosoma cruzi. Microbes Infect (2003) 0.95
The carboxyl-terminal domain of connexin43 is a negative modulator of neuronal differentiation. J Biol Chem (2010) 0.94
Bone marrow stromal cells improve cardiac performance in healed infarcted rat hearts. Am J Physiol Heart Circ Physiol (2004) 0.93
Contribution of pannexin1 to experimental autoimmune encephalomyelitis. PLoS One (2013) 0.91
Point mutation in the mouse P2X7 receptor affects intercellular calcium waves in astrocytes. ASN Neuro (2009) 0.91
Evidence for a perforin-mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection. Int J Exp Pathol (2002) 0.91
Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics. J Membr Biol (2007) 0.90
Ultrasound imaging in an experimental model of fatty liver disease and cirrhosis in rats. BMC Vet Res (2010) 0.90
C terminus of the P2X7 receptor: treasure hunting. Purinergic Signal (2011) 0.89
Biodistribution of bone marrow mononuclear cells in chronic chagasic cardiomyopathy after intracoronary injection. Int J Cardiol (2010) 0.89
Modulation of P2X(7) purinergic receptor in macrophages by Leishmania amazonensis and its role in parasite elimination. Microbes Infect (2009) 0.88
Implication of purinergic P2X7 receptor in M. tuberculosis infection and host interaction mechanisms: a mouse model study. Immunobiology (2013) 0.88
Expression of purinergic receptors and modulation of P2X7 function by the inflammatory cytokine IFNgamma in human epithelial cells. Biochim Biophys Acta (2009) 0.88
Extracellular ATP induces cell death in human intestinal epithelial cells. Biochim Biophys Acta (2012) 0.88
Characterization of ATP-induced cell death in the GL261 mouse glioma. J Cell Biochem (2010) 0.87
Gap junction reduction in cardiomyocytes following transforming growth factor-beta treatment and Trypanosoma cruzi infection. Mem Inst Oswaldo Cruz (2009) 0.87
Effects of mesenchymal stem cell therapy on the time course of pulmonary remodeling depend on the etiology of lung injury in mice. Crit Care Med (2013) 0.87
Functional and transcriptomic recovery of infarcted mouse myocardium treated with bone marrow mononuclear cells. Stem Cell Rev (2012) 0.87
Interleukin-1beta affects calcium signaling and in vitro cell migration of astrocyte progenitors. J Neuroimmunol (2008) 0.87
Characterizing the presence and sensitivity of the P2X7 receptor in different compartments of the gut. J Innate Immun (2012) 0.86
A stochastic two-dimensional model of intercellular Ca2+ wave spread in glia. Biophys J (2005) 0.86
Leukotriene B4 modulates P2X7 receptor-mediated Leishmania amazonensis elimination in murine macrophages. J Immunol (2014) 0.86
Prophylactic systemic P2X7 receptor blockade prevents experimental colitis. Biochim Biophys Acta (2013) 0.86
Granulocyte-colony stimulating factor treatment of chronic myocardial infarction. Cardiovasc Drugs Ther (2010) 0.85
The role of P2 receptors in controlling infections by intracellular pathogens. Purinergic Signal (2007) 0.84
Effects of bone marrow-derived mononuclear cells from healthy or acute respiratory distress syndrome donors on recipient lung-injured mice. Crit Care Med (2014) 0.84
Apoptosis-inducing factor of a cytotoxic T cell line: involvement of a secretory phospholipase A2. Cell Tissue Res (2006) 0.83
Differential modulation of ATP-induced P2X7-associated permeabilities to cations and anions of macrophages by infection with Leishmania amazonensis. PLoS One (2011) 0.83
Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease. Inflamm Bowel Dis (2014) 0.83
Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages. Immunobiology (2010) 0.83
Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion. J Innate Immun (2014) 0.82
Time course of echocardiographic and electrocardiographic parameters in myocardial infarct in rats. An Acad Bras Cienc (2007) 0.82
Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X(4) receptors. Infect Immun (2012) 0.81
Information processing and transmission in glia: calcium signaling and transmitter release. Glia (2006) 0.81
Cellular cardiomyoplasty in large myocardial infarction: can the beneficial effect be enhanced by ACE-inhibitor therapy? Eur J Heart Fail (2007) 0.81
Infection with Leishmania amazonensis upregulates purinergic receptor expression and induces host-cell susceptibility to UTP-mediated apoptosis. Cell Microbiol (2011) 0.81
P2X7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis. Exp Dermatol (2013) 0.81
The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis. J Innate Immun (2015) 0.80
Acanthamoeba interaction with extracellular matrix glycoproteins: biological and biochemical characterization and role in cytotoxicity and invasiveness. J Eukaryot Microbiol (2009) 0.79
Endothelial P2X7 receptors' expression is reduced by schistosomiasis. Purinergic Signal (2012) 0.79
Lipid metabolism modulation by the P2X7 receptor in the immune system and during the course of infection: new insights into the old view. Purinergic Signal (2011) 0.79
Pharmacological and molecular characterization of functional P2 receptors in rat embryonic cardiomyocytes. Purinergic Signal (2014) 0.79
Cell-based therapy in Chagas disease. Adv Parasitol (2011) 0.79
Adipose-derived stromal cell therapy improves cardiac function after coronary occlusion in rats. Cell Transplant (2012) 0.79
Early expression of adenosine 5'-triphosphate-gated P2X7 receptors in the developing rat pancreas. Pancreas (2007) 0.79
Tritrichomonas foetus: the role played by iron during parasite interaction with epithelial cells. Exp Parasitol (2003) 0.78
Modulation of P2X7 receptor expression in macrophages from mineral oil-injected mice. Immunobiology (2008) 0.78
Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis. Front Integr Neurosci (2007) 0.78
Electrophysiology of cardiac myocytes of Aplysia brasiliana. Comp Biochem Physiol A Mol Integr Physiol (2002) 0.78
[Not Available]. Interdiscip Perspect Infect Dis (2009) 0.78
Cellular alarms and whispers contribute to the polyphonic melody of danger signals required for immunity. Microbes Infect (2012) 0.77
Presence of the P2X(7) purinergic receptor on immune cells that invade the rat endometrium during oestrus. J Reprod Immunol (2005) 0.77
Effects of platelet-activating factor on the interaction of Trypanosoma cruzi with Rhodnius prolixus. Parasitol Res (2010) 0.76
Effect of extracellular ATP on the human leukaemic cell line K562 and its multidrug counterpart. Mol Cell Biochem (2006) 0.76
Group B Streptococcus induces tyrosine phosphorylation of annexin V and glutathione S-transferase in human umbilical vein endothelial cells. Int J Mol Med (2009) 0.76
Neuroblast migration and P2Y(1) receptor mediated calcium signalling depend on 9-O-acetyl GD3 ganglioside. ASN Neuro (2012) 0.75
Voltage-dependent calcium and chloride currents in S17 bone marrow stromal cell line. J Cell Physiol (2010) 0.75