Published in Plant Physiol on April 19, 2013
Dissecting the phenotypic components of crop plant growth and drought responses based on high-throughput image analysis. Plant Cell (2014) 1.43
Advanced phenotyping and phenotype data analysis for the study of plant growth and development. Front Plant Sci (2015) 1.13
Bulked sample analysis in genetics, genomics and crop improvement. Plant Biotechnol J (2016) 0.84
The Arabidopsis MYB96 Transcription Factor Is a Positive Regulator of ABSCISIC ACID-INSENSITIVE4 in the Control of Seed Germination. Plant Physiol (2015) 0.84
A new method to infer causal phenotype networks using QTL and phenotypic information. PLoS One (2014) 0.79
Metabolic patterns associated with the seasonal rhythm of seed survival after dehydration in germinated seeds of Schismus arabicus. BMC Plant Biol (2015) 0.75
Network-guided GWAS improves identification of genes affecting free amino acids. Plant Physiol (2016) 0.75
Physiological and biochemical responses of Ricinus communis seedlings to different temperatures: a metabolomics approach. BMC Plant Biol (2014) 0.75
R/qtl: QTL mapping in experimental crosses. Bioinformatics (2003) 22.38
Metabolite profiling for plant functional genomics. Nat Biotechnol (2000) 8.74
Genetical genomics: the added value from segregation. Trends Genet (2001) 8.23
Seed Germination and Dormancy. Plant Cell (1997) 7.79
Fundamentals of experimental design for cDNA microarrays. Nat Genet (2002) 7.49
Technical advance: simultaneous analysis of metabolites in potato tuber by gas chromatography-mass spectrometry. Plant J (2000) 4.64
Gene duplication in the diversification of secondary metabolism: tandem 2-oxoglutarate-dependent dioxygenases control glucosinolate biosynthesis in Arabidopsis. Plant Cell (2001) 4.61
Gene-environment interaction in yeast gene expression. PLoS Biol (2008) 4.48
The genetics of plant metabolism. Nat Genet (2006) 4.28
Bay-0 x Shahdara recombinant inbred line population: a powerful tool for the genetic dissection of complex traits in Arabidopsis. Theor Appl Genet (2002) 3.83
Mapping determinants of gene expression plasticity by genetical genomics in C. elegans. PLoS Genet (2006) 3.39
MetAlign: interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing. Anal Chem (2009) 3.30
GC-MS libraries for the rapid identification of metabolites in complex biological samples. FEBS Lett (2005) 3.29
Natural allelic variation at seed size loci in relation to other life history traits of Arabidopsis thaliana. Proc Natl Acad Sci U S A (1999) 3.20
GABA in plants: just a metabolite? Trends Plant Sci (2004) 3.12
Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis. Genetics (2006) 3.10
Genetic mechanisms and evolutionary significance of natural variation in Arabidopsis. Nature (2006) 3.00
Genome-wide profiling of stored mRNA in Arabidopsis thaliana seed germination: epigenetic and genetic regulation of transcription in seed. Plant J (2005) 2.97
Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci. Proc Natl Acad Sci U S A (2007) 2.94
What has natural variation taught us about plant development, physiology, and adaptation? Plant Cell (2009) 2.94
Pollen tube growth and guidance is regulated by POP2, an Arabidopsis gene that controls GABA levels. Cell (2003) 2.80
Genetical genomics: spotlight on QTL hotspots. PLoS Genet (2008) 2.63
The metabolic signature related to high plant growth rate in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2007) 2.44
Comparative quantitative trait loci mapping of aliphatic, indolic and benzylic glucosinolate production in Arabidopsis thaliana leaves and seeds. Genetics (2001) 2.33
System-wide molecular evidence for phenotypic buffering in Arabidopsis. Nat Genet (2009) 2.20
Linking metabolic QTLs with network and cis-eQTLs controlling biosynthetic pathways. PLoS Genet (2007) 2.15
Development of a near-isogenic line population of Arabidopsis thaliana and comparison of mapping power with a recombinant inbred line population. Genetics (2006) 2.15
Arabidopsis seed development and germination is associated with temporally distinct metabolic switches. Plant Physiol (2006) 2.01
R/qtl: high-throughput multiple QTL mapping. Bioinformatics (2010) 1.99
Expression quantitative trait loci are highly sensitive to cellular differentiation state. PLoS Genet (2009) 1.92
Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling viability. Plant J (2007) 1.91
From one amino acid to another: tRNA-dependent amino acid biosynthesis. Nucleic Acids Res (2008) 1.88
Quantitative trait loci controlling root growth and architecture in Arabidopsis thaliana confirmed by heterogeneous inbred family. Theor Appl Genet (2005) 1.84
Biochemical networks and epistasis shape the Arabidopsis thaliana metabolome. Plant Cell (2008) 1.84
First off the mark: early seed germination. J Exp Bot (2011) 1.82
Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation. PLoS Biol (2012) 1.82
AraGEM, a genome-scale reconstruction of the primary metabolic network in Arabidopsis. Plant Physiol (2009) 1.81
Identification of QTLs controlling gene expression networks defined a priori. BMC Bioinformatics (2006) 1.76
Identification of metabolic and biomass QTL in Arabidopsis thaliana in a parallel analysis of RIL and IL populations. Plant J (2007) 1.74
Quantitative trait loci analysis of nitrogen use efficiency in Arabidopsis. Plant Physiol (2003) 1.69
Combining genome-wide association mapping and transcriptional networks to identify novel genes controlling glucosinolates in Arabidopsis thaliana. PLoS Biol (2011) 1.54
Identification of QTL controlling root growth response to phosphate starvation in Arabidopsis thaliana. Plant Cell Environ (2006) 1.49
Mapping metabolic and transcript temporal switches during germination in rice highlights specific transcription factors and the role of RNA instability in the germination process. Plant Physiol (2008) 1.45
Seed desiccation: a bridge between maturation and germination. Trends Plant Sci (2010) 1.43
Retention index thresholds for compound matching in GC-MS metabolite profiling. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 1.42
Leaf yellowing and anthocyanin accumulation are two genetically independent strategies in response to nitrogen limitation in Arabidopsis thaliana. Plant Cell Physiol (2005) 1.41
MSClust: a tool for unsupervised mass spectra extraction of chromatography-mass spectrometry ion-wise aligned data. Metabolomics (2011) 1.37
Construction of regulatory networks using expression time-series data of a genotyped population. Proc Natl Acad Sci U S A (2011) 1.31
The conservation and evolutionary modularity of metabolism. Genome Biol (2009) 1.24
Generalizing genetical genomics: getting added value from environmental perturbation. Trends Genet (2008) 1.23
Seed storage oil mobilization is important but not essential for germination or seedling establishment in Arabidopsis. Plant Physiol (2011) 1.23
Natural variation among Arabidopsis thaliana accessions for transcriptome response to exogenous salicylic acid. Plant Cell (2007) 1.21
Quantitative trait loci analysis of water and anion contents in interaction with nitrogen availability in Arabidopsis thaliana. Genetics (2003) 1.20
Genetic control of storage oil synthesis in seeds of Arabidopsis. Plant Physiol (2004) 1.18
Branched-Chain Amino Acid Metabolism in Arabidopsis thaliana. Arabidopsis Book (2010) 1.12
Natural variation for carbohydrate content in Arabidopsis. Interaction with complex traits dissected by quantitative genetics. Plant Physiol (2006) 1.11
A zinc knuckle protein that negatively controls morning-specific growth in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2008) 1.04
Metabolite profiling of germinating rice seeds. J Agric Food Chem (2008) 1.00
Analysis of natural allelic variation controlling Arabidopsis thaliana seed germinability in response to cold and dark: identification of three major quantitative trait loci. Mol Plant (2007) 0.98
Quantitative genetics in the age of omics. Curr Opin Plant Biol (2008) 0.97
Targeted enhancement of glutamate-to-γ-aminobutyrate conversion in Arabidopsis seeds affects carbon-nitrogen balance and storage reserves in a development-dependent manner. Plant Physiol (2011) 0.96
Visualizing the genetic landscape of Arabidopsis seed performance. Plant Physiol (2011) 0.95
Untargeted metabolic quantitative trait loci analyses reveal a relationship between primary metabolism and potato tuber quality. Plant Physiol (2012) 0.90
Isolation and characterization of cDNA clones for the e1beta and E2 subunits of the branched-chain alpha-ketoacid dehydrogenase complex in Arabidopsis. J Biol Chem (2000) 0.90
Transcriptome- and proteome-wide analyses of seed germination. C R Biol (2008) 0.90
designGG: an R-package and web tool for the optimal design of genetical genomics experiments. BMC Bioinformatics (2009) 0.88
Advances in genetical genomics of plants. Curr Genomics (2009) 0.86
Multi-dimensional regulation of metabolic networks shaping plant development and performance. J Exp Bot (2011) 0.86
Arabidopsis seed germination under abiotic stress as a concert of action of phytohormones. OMICS (2011) 0.86
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet (2005) 6.91
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med (2006) 6.18
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci U S A (2009) 4.46
The genetics of plant metabolism. Nat Genet (2006) 4.28
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Trends in prevalence of HIV, syphilis, hepatitis C, hepatitis B, and sexual risk behavior among men who have sex with men. Results of 3 consecutive respondent-driven sampling surveys in Beijing, 2004 through 2006. J Acquir Immune Defic Syndr (2007) 3.83
Substrate modulus directs neural stem cell behavior. Biophys J (2008) 3.81
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet (2011) 3.65
Stress hormone-mediated invasion of ovarian cancer cells. Clin Cancer Res (2006) 3.58
Sequence polymorphisms cause many false cis eQTLs. PLoS One (2007) 3.54
Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry. Nat Protoc (2007) 3.41
Mapping determinants of gene expression plasticity by genetical genomics in C. elegans. PLoS Genet (2006) 3.39
Mapping the epigenetic basis of complex traits. Science (2014) 3.13
Epigenome dynamics: a quantitative genetics perspective. Nat Rev Genet (2008) 3.13
Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci. Proc Natl Acad Sci U S A (2007) 2.94
What has natural variation taught us about plant development, physiology, and adaptation? Plant Cell (2009) 2.94
Genetical genomics: spotlight on QTL hotspots. PLoS Genet (2008) 2.63
Starch as a major integrator in the regulation of plant growth. Proc Natl Acad Sci U S A (2009) 2.47
Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding. Immunity (2012) 2.47
Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg (2004) 2.46
Gene expression profiles of Arabidopsis Cvi seeds during dormancy cycling indicate a common underlying dormancy control mechanism. Plant J (2006) 2.41
Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects. Am J Physiol Endocrinol Metab (2009) 2.39
The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics (2010) 2.37
Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry. Proteomics (2005) 2.34
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Cancer Res (2006) 2.32
Rejection of unfair offers in the ultimatum game is no evidence of strong reciprocity. Proc Natl Acad Sci U S A (2012) 2.31
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet (2012) 2.29
Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens. J Clin Microbiol (2006) 2.27
Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice. J Clin Invest (2008) 2.24
System-wide molecular evidence for phenotypic buffering in Arabidopsis. Nat Genet (2009) 2.20
The Human Ageing Genomic Resources: online databases and tools for biogerontologists. Aging Cell (2008) 2.19
Big data, but are we ready? Nat Rev Genet (2011) 2.16
An oligonucleotide microarray for microRNA expression analysis based on labeling RNA with quantum dot and nanogold probe. Nucleic Acids Res (2005) 2.15
R/qtl: high-throughput multiple QTL mapping. Bioinformatics (2010) 1.99
Medium scale integration of molecular logic gates in an automaton. Nano Lett (2006) 1.98
Crystal structures of a ligand-free MthK gating ring: insights into the ligand gating mechanism of K+ channels. Cell (2006) 1.98
Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology (2008) 1.97
Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer. J Clin Oncol (2010) 1.95
Characterization of RNA in saliva. Clin Chem (2006) 1.93
Expression quantitative trait loci are highly sensitive to cellular differentiation state. PLoS Genet (2009) 1.92
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis. Proc Natl Acad Sci U S A (2009) 1.91
Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer. J Natl Cancer Inst (2006) 1.87
The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biol (2013) 1.87
Automated chemical crystallography. J Am Chem Soc (2010) 1.86
Novel insights into K+ selectivity from high-resolution structures of an open K+ channel pore. Nat Struct Mol Biol (2010) 1.86
TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo. EMBO J (2007) 1.85
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet (2012) 1.79
PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis. Anal Chem (2011) 1.78
Sox2 protects neural stem cells from apoptosis via up-regulating survivin expression. Biochem J (2013) 1.77
Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Mol Pharmacol (2008) 1.75
T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities. J Biol Chem (2002) 1.75
A Galpha subunit controls zoospore motility and virulence in the potato late blight pathogen Phytophthora infestans. Mol Microbiol (2004) 1.72
Reverse breeding in Arabidopsis thaliana generates homozygous parental lines from a heterozygous plant. Nat Genet (2012) 1.70
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Comparative genomics reveals a deep-sea sediment-adapted life style of Pseudoalteromonas sp. SM9913. ISME J (2010) 1.69
Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma. Cancer Res (2007) 1.68
Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J (2006) 1.66
Complex nature of SNP genotype effects on gene expression in primary human leucocytes. BMC Med Genomics (2009) 1.64
Concurrent analysis of loss of heterozygosity (LOH) and copy number abnormality (CNA) for oral premalignancy progression using the Affymetrix 10K SNP mapping array. Hum Genet (2004) 1.64
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet (2012) 1.64
Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1α in MSCs. Biochem Biophys Res Commun (2010) 1.64
Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells. Clin Cancer Res (2005) 1.63
MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects. Bioinformatics (2011) 1.60
Co-receptor requirements for fibroblast growth factor-19 signaling. J Biol Chem (2007) 1.59
The relationship between obesity and blood pressure differs by ethnicity in Sydney school children. Am J Hypertens (2008) 1.59
Angle- and spectral-dependent light scattering from plasmonic nanocups. ACS Nano (2011) 1.58
The role of SDF-1-CXCR4/CXCR7 axis in the therapeutic effects of hypoxia-preconditioned mesenchymal stem cells for renal ischemia/reperfusion injury. PLoS One (2012) 1.56
p21-Activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2). J Biol Chem (2012) 1.55
Stress hormones regulate interleukin-6 expression by human ovarian carcinoma cells through a Src-dependent mechanism. J Biol Chem (2007) 1.54
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules. BMC Bioinformatics (2010) 1.53
Enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated Salmonella carrying a plasmid co-expressing p53 gene and mdm2 siRNA. Cancer Lett (2013) 1.53
Development of an advanced electrochemical DNA biosensor for bacterial pathogen detection. J Mol Diagn (2007) 1.52
Oral anticoagulation continuation compared with heparin bridging therapy among high risk patients undergoing implantation of cardiac rhythm devices: a meta-analysis. Thromb Haemost (2012) 1.52
miR-375 is down-regulated in squamous cervical cancer and inhibits cell migration and invasion via targeting transcription factor SP1. Am J Pathol (2011) 1.52
MetaNetwork: a computational protocol for the genetic study of metabolic networks. Nat Protoc (2007) 1.50
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. Am J Hum Genet (2012) 1.49
Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China. Proc Natl Acad Sci U S A (2013) 1.49
RNA interference knockdown of DNA methyl-transferase 3 affects gene alternative splicing in the honey bee. Proc Natl Acad Sci U S A (2013) 1.49
SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation. J Virol (2007) 1.47
Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population. Nat Genet (2011) 1.46
The multifunctional human p100 protein 'hooks' methylated ligands. Nat Struct Mol Biol (2007) 1.46
Common and well-documented (CWD) alleles of human leukocyte antigen-A, -B, -C, -DRB1, and -DQB1 loci for the Chinese Han population do not quite correlate with the ASHI CWD alleles. Hum Immunol (2011) 1.45
Structural requirements for differential sensitivity of KCNQ K+ channels to modulation by Ca2+/calmodulin. Mol Biol Cell (2005) 1.45
Identification of reference genes for RT-qPCR expression analysis in Arabidopsis and tomato seeds. Plant Cell Physiol (2011) 1.44
Mediation of multiple pathways regulating cell proliferation, migration, and apoptosis in the human malignant glioma cell line U87MG via unphosphorylated STAT1: laboratory investigation. J Neurosurg (2013) 1.44
Beyond standardization: dynamic software infrastructures for systems biology. Nat Rev Genet (2007) 1.44
Genome characterization of the oleaginous fungus Mortierella alpina. PLoS One (2011) 1.43
The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Nat Neurosci (2009) 1.43