A novel acetylcholine bioensor and its electrochemical behavior.

Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med (2002) 21.28

Genome sequence of Aedes aegypti, a major arbovirus vector. Science (2007) 9.19

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet (2009) 7.48

Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada. J Natl Cancer Inst (2006) 6.73

Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res (2006) 6.52

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nat Genet (2013) 4.48

A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One (2009) 3.86

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells. Nat Med (2012) 3.34

Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function. J Immunol (2006) 3.12

Verification and unmasking of widely used human esophageal adenocarcinoma cell lines. J Natl Cancer Inst (2010) 2.79

Induction of myeloid-derived suppressor cells by tumor exosomes. Int J Cancer (2009) 2.64

The iron chelator deferasirox protects mice from mucormycosis through iron starvation. J Clin Invest (2007) 2.48

Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. EMBO J (2002) 2.46

Anisotropic mechanosensing by mesenchymal stem cells. Proc Natl Acad Sci U S A (2006) 2.43

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology (2007) 2.43

Anisamide-targeted stealth liposomes: a potent carrier for targeting doxorubicin to human prostate cancer cells. Int J Cancer (2004) 2.31

ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells. EMBO Rep (2006) 2.26

Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res (2012) 2.26

Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer. Gynecol Oncol (2011) 2.19

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Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. Gastroenterology (2012) 2.11

Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. Cancer Cell (2009) 2.10

Boolean network simulations for life scientists. Source Code Biol Med (2008) 2.05

Differential effects of equiaxial and uniaxial strain on mesenchymal stem cells. Biotechnol Bioeng (2004) 2.05

The prevalence of BRCA1 mutations among young women with triple-negative breast cancer. BMC Cancer (2009) 2.01

Antithrombogenic property of bone marrow mesenchymal stem cells in nanofibrous vascular grafts. Proc Natl Acad Sci U S A (2007) 2.01

Myotube assembly on nanofibrous and micropatterned polymers. Nano Lett (2006) 2.00

Proteomic profiling of bone marrow mesenchymal stem cells upon transforming growth factor beta1 stimulation. J Biol Chem (2004) 1.96

The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-β. Biomaterials (2011) 1.93

Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages. Mol Oncol (2007) 1.88

Mutations in NR5A1 associated with ovarian insufficiency. N Engl J Med (2009) 1.88

Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene. Oncogene (2004) 1.83

Bioactive nanofibers: synergistic effects of nanotopography and chemical signaling on cell guidance. Nano Lett (2007) 1.81

The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus. Infect Immun (2008) 1.77

Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophys J (2004) 1.77

Transforming growth factor-beta and notch signaling mediate stem cell differentiation into smooth muscle cells. Stem Cells (2010) 1.74

Thymus exosomes-like particles induce regulatory T cells. J Immunol (2008) 1.73

Draft genome of the kiwifruit Actinidia chinensis. Nat Commun (2013) 1.72

Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency. J Clin Endocrinol Metab (2009) 1.68

Biomedical applications of graphene. Theranostics (2012) 1.67

Differentiation of multipotent vascular stem cells contributes to vascular diseases. Nat Commun (2012) 1.66

Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure. Circulation (2004) 1.64

Regulation of vascular smooth muscle cells by micropatterning. Biochem Biophys Res Commun (2003) 1.63

Two small GTPases act in concert with the bactofilin cytoskeleton to regulate dynamic bacterial cell polarity. Dev Cell (2013) 1.63

Gene amplification in esophageal adenocarcinomas and Barrett's with high-grade dysplasia. Clin Cancer Res (2003) 1.62

Biophysical regulation of epigenetic state and cell reprogramming. Nat Mater (2013) 1.55

Mutations in the p53 tumor suppressor gene and early onset breast cancer. Cancer Biol Ther (2002) 1.52

Cationic lipids enhance siRNA-mediated interferon response in mice. Biochem Biophys Res Commun (2005) 1.50

Homogeneous gold-catalyzed oxidative carboheterofunctionalization of alkenes. J Am Chem Soc (2010) 1.49

Assessment of ischemia-modified albumin levels for emergency room diagnosis of acute coronary syndrome. Int J Cardiol (2010) 1.49

S-1-based therapy versus S-1 monotherapy in advanced gastric cancer: a meta-analysis. Tumour Biol (2014) 1.48

Sporadic onset of erythermalgia: a gain-of-function mutation in Nav1.7. Ann Neurol (2006) 1.48

Injectable biopolymers enhance angiogenesis after myocardial infarction. Tissue Eng (2006) 1.46

Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. J Clin Invest (2012) 1.45

Cellular electrophysiology of canine pulmonary vein cardiomyocytes: action potential and ionic current properties. J Physiol (2003) 1.45

Phosphorylated FADD induces NF-kappaB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas. Proc Natl Acad Sci U S A (2005) 1.44

PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells. Proc Natl Acad Sci U S A (2004) 1.42

Long noncoding RNAs in development and disease of the central nervous system. Trends Genet (2013) 1.42

DNA origami as a carrier for circumvention of drug resistance. J Am Chem Soc (2012) 1.42

miR-135a Suppresses Calcification in Senescent VSMCs by Regulating KLF4/STAT3 Pathway. Curr Vasc Pharmacol (2016) 1.42

Alkynes as equivalents of alpha-diazo ketones in generating alpha-oxo metal carbenes: a gold-catalyzed expedient synthesis of dihydrofuran-3-ones. J Am Chem Soc (2010) 1.41

Degradation of the endoplasmic reticulum by autophagy during endoplasmic reticulum stress in Arabidopsis. Plant Cell (2012) 1.38

A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death. J Immunol (2006) 1.36

Hierarchical modeling for rare event detection and cell subset alignment across flow cytometry samples. PLoS Comput Biol (2013) 1.35

Human male infertility associated with mutations in NR5A1 encoding steroidogenic factor 1. Am J Hum Genet (2010) 1.35

Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair. J Biol Chem (2010) 1.34

Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase-generated superoxide. J Clin Invest (2008) 1.33

Gold-catalyzed highly regioselective oxidation of C-C triple bonds without acid additives: propargyl moieties as masked α,β-unsaturated carbonyls. J Am Chem Soc (2010) 1.33

Immature myeloid cells induced by a high-fat diet contribute to liver inflammation. Hepatology (2009) 1.33

Progesterone inhibits the estrogen-induced phosphoinositide 3-kinase-->AKT-->GSK-3beta-->cyclin D1-->pRB pathway to block uterine epithelial cell proliferation. Mol Endocrinol (2005) 1.33

Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infection. PLoS One (2012) 1.32

Gold-catalyzed one-step practical synthesis of oxetan-3-ones from readily available propargylic alcohols. J Am Chem Soc (2010) 1.31

NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension. Am J Physiol Regul Integr Comp Physiol (2008) 1.31

A two-step, formal [4 + 2] approach toward piperidin-4-ones via Au catalysis. J Am Chem Soc (2009) 1.30

Cell death in development: shaping the embryo. Histochem Cell Biol (2006) 1.30

DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons. Neuron (2011) 1.30

Steroidogenic factor-1 (SF-1, NR5A1) and human disease. Mol Cell Endocrinol (2010) 1.29

Type 1 ryanodine receptor in cardiac mitochondria: transducer of excitation-metabolism coupling. Biochim Biophys Acta (2005) 1.28

Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma. Neoplasia (2006) 1.28

Mutational analysis of steroidogenic factor 1 (NR5a1) in 24 boys with bilateral anorchia: a French collaborative study. Hum Reprod (2007) 1.27

A flexible and stereoselective synthesis of azetidin-3-ones through gold-catalyzed intermolecular oxidation of alkynes. Angew Chem Int Ed Engl (2011) 1.27

The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis. Mol Microbiol (2010) 1.27

Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins. Blood (2012) 1.26

The phosphatidylinositol 3-phosphate phosphatase myotubularin- related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1. Mol Cell Biol (2005) 1.26

A highly efficient preparative method of alpha-ylidene-beta-diketones via Au(III)-catalyzed acyl migration of propargylic esters. J Am Chem Soc (2006) 1.26

Materials design in the performance of all-ceramic crowns. Biomaterials (2004) 1.25

Tubule-specific ablation of endogenous β-catenin aggravates acute kidney injury in mice. Kidney Int (2012) 1.25

Anaplastic large cell lymphoma involving the breast: a clinicopathologic study of 6 cases and review of the literature. Arch Pathol Lab Med (2009) 1.24

Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling. J Cell Sci (2002) 1.24

Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes. Nat Struct Mol Biol (2008) 1.23

A novel multiresolution spatiotemporal saliency detection model and its applications in image and video compression. IEEE Trans Image Process (2010) 1.23

Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G-protein action. Mol Syst Biol (2010) 1.23

CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma. Clin Cancer Res (2010) 1.23

The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency. Eur J Endocrinol (2009) 1.23

Extremely high prevalence of neural tube defects in a 4-county area in Shanxi Province, China. Birth Defects Res A Clin Mol Teratol (2006) 1.21

Common and unique elements of the ABA-regulated transcriptome of Arabidopsis guard cells. BMC Genomics (2011) 1.21

Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma. Ann Thorac Surg (2012) 1.21

Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin. Am J Pathol (2006) 1.20

A novel point mutation in the KCNJ5 gene causing primary hyperaldosteronism and early-onset autosomal dominant hypertension. J Clin Endocrinol Metab (2012) 1.20

Role of cell surface heparan sulfate proteoglycans in endothelial cell migration and mechanotransduction. J Cell Physiol (2005) 1.20