Published in Epigenetics on April 17, 2013
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. Lancet Diabetes Endocrinol (2015) 2.46
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Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci. Hum Mol Genet (2015) 1.45
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An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss. Genome Biol (2015) 1.19
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Body mass index is associated with gene methylation in estrogen receptor-positive breast tumors. Cancer Epidemiol Biomarkers Prev (2015) 0.85
Novel epigenetic determinants of type 2 diabetes in Mexican-American families. Hum Mol Genet (2015) 0.84
Roux-en Y gastric bypass surgery induces genome-wide promoter-specific changes in DNA methylation in whole blood of obese patients. PLoS One (2015) 0.83
Metabolic thrift and the genetic basis of human obesity. Ann Surg (2014) 0.83
Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood. Epigenetics (2015) 0.82
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Obesity is associated with more activated neutrophils in African American male youth. Int J Obes (Lond) (2014) 0.81
Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathy. Clin Epigenetics (2014) 0.80
Quantitative methylation level of the EPHX1 promoter in peripheral blood DNA is associated with polycystic ovary syndrome. PLoS One (2014) 0.79
Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients. Mol Metab (2016) 0.79
DNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation. Twin Res Hum Genet (2014) 0.79
Associations between whole peripheral blood fatty acids and DNA methylation in humans. Sci Rep (2016) 0.79
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Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population. Clin Epigenetics (2015) 0.78
Clinical applications of epigenetics in cardiovascular disease: the long road ahead. Transl Res (2014) 0.78
Variability in Zucker diabetic fatty rats: differences in disease progression in hyperglycemic and normoglycemic animals. Diabetes Metab Syndr Obes (2014) 0.77
LINE-1 methylation is positively associated with healthier lifestyle but inversely related to body fat mass in healthy young individuals. Epigenetics (2016) 0.77
DNA methylation levels are highly correlated between pooled samples and averaged values when analysed using the Infinium HumanMethylation450 BeadChip array. Clin Epigenetics (2015) 0.77
Methylation Microarray Studies Highlight PDGFA Expression as a Factor in Biliary Atresia. PLoS One (2016) 0.77
SERPINE1, PAI-1 protein coding gene, methylation levels and epigenetic relationships with adiposity changes in obese subjects with metabolic syndrome features under dietary restriction. J Clin Biochem Nutr (2013) 0.77
Stochastic epigenetic outliers can define field defects in cancer. BMC Bioinformatics (2016) 0.76
Exploring possible epigenetic mediation of early-life environmental exposures on adiposity and obesity development. Int J Epidemiol (2015) 0.76
Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity. Epigenetics (2016) 0.76
Epigenetic Mechanisms of the Aging Human Retina. J Exp Neurosci (2016) 0.76
DNA cytosine hydroxymethylation levels are distinct among non-overlapping classes of peripheral blood leukocytes. J Immunol Methods (2016) 0.75
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass. Diabetol Metab Syndr (2017) 0.75
Social exclusion changes histone modifications H3K4me3 and H3K27ac in liver tissue of wild house mice. PLoS One (2015) 0.75
DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients. Sci Rep (2017) 0.75
An epigenome-wide association study in whole blood of measures of adiposity among Ghanaians: the RODAM study. Clin Epigenetics (2017) 0.75
Connecting the Dots Between Fatty Acids, Mitochondrial Function, and DNA Methylation in Atherosclerosis. Curr Atheroscler Rep (2017) 0.75
Epigenetics, obesity and early-life cadmium or lead exposure. Epigenomics (2016) 0.75
Interaction between obesity and the Hypoxia Inducible Factor 3 Alpha Subunit rs3826795 polymorphism in relation with plasma alanine aminotransferase. BMC Med Genet (2017) 0.75
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Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol (2013) 5.89
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Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation. Genome Med (2012) 1.65
Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions. Bioinformatics (2012) 1.51
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The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
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A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
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Prevalence, awareness, treatment, and control of hypertension in china. Hypertension (2002) 4.18
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Ethnic and gender differences in ambulatory blood pressure trajectories: results from a 15-year longitudinal study in youth and young adults. Circulation (2006) 3.26
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Evidence for independent heritability of the glycation gap (glycosylation gap) fraction of HbA1c in nondiabetic twins. Diabetes Care (2006) 2.87
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
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Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell (2011) 2.30
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet (2012) 2.29
Activation markers of coagulation and fibrinolysis in twins: heritability of the prethrombotic state. Lancet (2002) 2.26
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet (2010) 2.24
Obesity related methylation changes in DNA of peripheral blood leukocytes. BMC Med (2010) 2.24
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
The chromosome 9p21 risk locus is associated with angiographic severity and progression of coronary artery disease. Eur Heart J (2010) 2.04
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Physiology of long pranayamic breathing: neural respiratory elements may provide a mechanism that explains how slow deep breathing shifts the autonomic nervous system. Med Hypotheses (2006) 1.95
Vitamin D3 supplementation for 16 weeks improves flow-mediated dilation in overweight African-American adults. Am J Hypertens (2011) 1.91
House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus infection. Proc Natl Acad Sci U S A (2013) 1.88
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Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity. Atherosclerosis (2011) 1.80
A longitudinal study of blood pressure variability in African-American and European American youth. J Hypertens (2010) 1.76
Low 25-hydroxyvitamin D levels in adolescents: race, season, adiposity, physical activity, and fitness. Pediatrics (2010) 1.76
Heritability and seasonal variability of vitamin D concentrations in male twins. Am J Clin Nutr (2010) 1.73
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
Depressive symptoms and metabolic syndrome: is inflammation the underlying link? Biol Psychiatry (2008) 1.70
A 16-week randomized clinical trial of 2000 international units daily vitamin D3 supplementation in black youth: 25-hydroxyvitamin D, adiposity, and arterial stiffness. J Clin Endocrinol Metab (2010) 1.69
Genome-wide association analysis identifies multiple loci related to resting heart rate. Hum Mol Genet (2010) 1.67
Adolescent obesity, bone mass, and cardiometabolic risk factors. J Pediatr (2011) 1.66
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Genetic influence on early age-related maculopathy: a twin study. Ophthalmology (2002) 1.57
Genetic influences on daytime and night-time blood pressure: similarities and differences. J Hypertens (2009) 1.57
Decreased heart rate variability is associated with higher levels of inflammation in middle-aged men. Am Heart J (2008) 1.55
Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography. Circ Cardiovasc Genet (2012) 1.54
Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. Cancer Res (2010) 1.54
Quantitative characterization of intrinsic disorder in polyglutamine: insights from analysis based on polymer theories. Biophys J (2007) 1.53
Heritabilities of apolipoprotein and lipid levels in three countries. Twin Res (2002) 1.50
Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity. J Pediatr (2010) 1.50
Duration of airborne Fel d 1 reduction after cat washing. J Allergy Clin Immunol (2006) 1.48
Genetic and environmental determinants of lipid profile in black and white youth: a study of four candidate genes. Ethn Dis (2005) 1.47
Long-term effects of stress reduction on mortality in persons > or = 55 years of age with systemic hypertension. Am J Cardiol (2005) 1.46
A randomized controlled trial of stress reduction in African Americans treated for hypertension for over one year. Am J Hypertens (2005) 1.45
Moderators of blood pressure development from childhood to adulthood: a 10-year longitudinal study. J Pediatr (2002) 1.45
Atomistic simulations of the effects of polyglutamine chain length and solvent quality on conformational equilibria and spontaneous homodimerization. J Mol Biol (2008) 1.43
A polymer physics perspective on driving forces and mechanisms for protein aggregation. Arch Biochem Biophys (2007) 1.41
Genetic epidemiological approaches in the study of risk factors for cardiovascular disease. Eur J Epidemiol (2004) 1.40
FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth. BMC Med Genet (2010) 1.38
Ethnic differences in resting heart rate variability: a systematic review and meta-analysis. Psychosom Med (2015) 1.31
Extensive association analysis between polymorphisms of PON gene cluster with coronary heart disease in Chinese Han population. Arterioscler Thromb Vasc Biol (2003) 1.31
The SH2B gene is associated with serum leptin and body fat in normal female twins. Obesity (Silver Spring) (2007) 1.30
Association study with 33 single-nucleotide polymorphisms in 11 candidate genes for hypertension in Chinese. Hypertension (2006) 1.30
Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors. Mol Cell Biol (2005) 1.30
Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet (2012) 1.29
dSLAM analysis of genome-wide genetic interactions in Saccharomyces cerevisiae. Methods (2007) 1.28
Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. PLoS One (2009) 1.28
Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet (2013) 1.27
Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study. Biol Psychiatry (2008) 1.27
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet (2011) 1.26
Cancer cells and normal cells differ in their requirements for Thoc1. Cancer Res (2007) 1.26
Heritability of QT interval: how much is explained by genes for resting heart rate? J Cardiovasc Electrophysiol (2007) 1.25
Genetic contribution to renal function and electrolyte balance: a twin study. Clin Sci (Lond) (2002) 1.24
Reconciling observations of sequence-specific conformational propensities with the generic polymeric behavior of denatured proteins. Biochemistry (2005) 1.23
Recovery from renal ischemia-reperfusion injury is associated with altered renal hemodynamics, blunted pressure natriuresis, and sodium-sensitive hypertension. Am J Physiol Regul Integr Comp Physiol (2009) 1.19
Lower bone mass in prepubertal overweight children with prediabetes. J Bone Miner Res (2010) 1.17
Ethnic differences and heritability of heart rate variability in African- and European American youth. Am J Cardiol (2005) 1.16
Bivariate genetic modeling of cardiovascular stress reactivity: does stress uncover genetic variance? Psychosom Med (2007) 1.16
The Georgia Cardiovascular Twin Study: influence of genetic predisposition and chronic stress on risk for cardiovascular disease and type 2 diabetes. Twin Res Hum Genet (2006) 1.16
Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia. J Am Coll Cardiol (2012) 1.15
Depressive symptoms and heart rate variability: evidence for a shared genetic substrate in a study of twins. Psychosom Med (2008) 1.12
Cardiovascular characteristics in American youth with prehypertension. Am J Hypertens (2007) 1.12
Prevalence of isolated systolic and isolated diastolic hypertension subtypes in China. Am J Hypertens (2004) 1.11