Published in PLoS One on May 06, 2013
HDAC9 promotes glioblastoma growth via TAZ-mediated EGFR pathway activation. Oncotarget (2015) 0.88
Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor. J Biol Chem (2015) 0.78
Loss of histone deacetylase HDAC1 induces cell death in Drosophila epithelial cells through JNK and Hippo signaling. Mech Dev (2016) 0.75
HDACi Valproic Acid (VPA) and Suberoylanilide Hydroxamic Acid (SAHA) Delay but Fail to Protect against Warm Hepatic Ischemia-Reperfusion Injury. PLoS One (2016) 0.75
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev (2007) 13.05
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell (2006) 12.72
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell (2003) 7.43
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell (2012) 6.80
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell (2003) 6.48
The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network. Nat Rev Cancer (2007) 5.78
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway. Nat Cell Biol (2003) 5.50
Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem (2007) 5.49
Hippo signaling: growth control and beyond. Development (2011) 5.25
Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development (1995) 5.18
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell (2011) 5.06
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol (2008) 5.02
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell (2009) 4.81
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. Nat Cell Biol (2011) 4.63
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell (2010) 4.59
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J (2000) 4.55
The Hippo pathway regulates Wnt/beta-catenin signaling. Dev Cell (2010) 4.49
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nat Genet (1999) 4.23
Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Mol Cell (2000) 3.65
In vivo regulation of Yorkie phosphorylation and localization. Development (2008) 3.51
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev (2010) 3.37
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol (2010) 3.08
Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer (2011) 3.06
Role of TAZ as mediator of Wnt signaling. Cell (2012) 3.05
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr Biol (2010) 2.97
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α. Nat Chem Biol (2010) 2.71
Clinical studies of histone deacetylase inhibitors. Clin Cancer Res (2009) 2.68
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway. Cancer Res (2008) 2.63
Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res (2011) 2.21
Upstream regulation of the hippo size control pathway. Curr Biol (2010) 2.09
Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer. Cancer Sci (2010) 2.04
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol (2012) 1.91
Wnt/β-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells. J Biol Chem (2012) 1.89
TAZ is a novel oncogene in non-small cell lung cancer. Oncogene (2011) 1.85
Yorkie: the final destination of Hippo signaling. Trends Cell Biol (2010) 1.65
Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction. Nat Cell Biol (2010) 1.64
Epithelial organization, cell polarity and tumorigenesis. Trends Cell Biol (2011) 1.59
Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells. Exp Cell Res (2004) 1.56
YAP oncogene overexpression supercharges colon cancer proliferation. Cell Cycle (2012) 1.34
NF-kappaB activation stimulates osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue by increasing TAZ expression. J Cell Physiol (2010) 1.31
As an independent unfavorable prognostic factor, IL-8 promotes metastasis of nasopharyngeal carcinoma through induction of epithelial-mesenchymal transition and activation of AKT signaling. Carcinogenesis (2012) 1.26
Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2010) 1.19
Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression. Cancer Res (2012) 1.17
The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition. J Biol Chem (2012) 1.17
TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma. Eur J Cancer (2010) 1.12
Transforming growth factor beta1 induces osteogenic differentiation of murine bone marrow stromal cells. Tissue Eng Part A (2010) 1.10
Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain. Cancer Res (2009) 1.09
Newcomers to the WW Domain-Mediated Network of the Hippo Tumor Suppressor Pathway. Genes Cancer (2010) 1.07
Factors secreted by human neuroblastoma mediated doxorubicin resistance by activating STAT3 and inhibiting apoptosis. Mol Med (2001) 1.01
Identification of midkine as a mediator for intercellular transfer of drug resistance. Oncogene (2005) 0.98
The hippo pathway. Cold Spring Harb Perspect Biol (2012) 0.96
The Hippo pathway controls polar cell fate through Notch signaling during Drosophila oogenesis. Dev Biol (2011) 0.93
Intersection of Hippo/YAP and Wnt/β-catenin signaling pathways. Acta Biochim Biophys Sin (Shanghai) (2012) 0.89
Role of the beta catenin destruction complex in mediating chemotherapy-induced senescence-associated secretory phenotype. PLoS One (2012) 0.82
Cellular conditioning with trichostatin A enhances the anti-stress response through up-regulation of HDAC4 and down-regulation of the IGF/Akt pathway. Aging Cell (2008) 0.80
Stress resistant human embryonic stem cells as a potential source for the identification of novel cancer stem cell markers. Cancer Lett (2009) 0.77
Control of multidrug resistance gene mdr1 and cancer resistance to chemotherapy by the longevity gene sirt1. Cancer Res (2005) 1.50
Early metastasizing spindle epithelial tumor with thymus-like differentiation (SETTLE) of the thyroid. Pediatr Dev Pathol (2005) 1.46
Mesenchymal hamartoma of the liver associated with features of Beckwith-Wiedemann syndrome and high serum alpha-fetoprotein levels. Pediatr Dev Pathol (2007) 1.26
Total parenteral nutrition induced liver pathology: an autopsy series of 24 newborn cases. Pediatr Dev Pathol (2004) 1.11
Amplification of mutated NRAS leading to congenital melanoma in neurocutaneous melanocytosis. Melanoma Res (2015) 1.06
BRAF mutations are also associated with neurocutaneous melanocytosis and large/giant congenital melanocytic nevi. Pediatr Dev Pathol (2014) 1.02
Pediatric sclerosing rhabdomyosarcoma. Int J Surg Pathol (2006) 1.01
Rhabdomyosarcoma, Wilms tumor, and deletion of the patched gene in Gorlin syndrome. Nat Clin Pract Oncol (2006) 0.99
Identification of midkine as a mediator for intercellular transfer of drug resistance. Oncogene (2005) 0.98
Prolonged red cell storage before transfusion increases extravascular hemolysis. J Clin Invest (2016) 0.97
Senescence-initiated reversal of drug resistance: specific role of cathepsin L. Cancer Res (2004) 0.95
Tetraiodothyroacetic acid, a small molecule integrin ligand, blocks angiogenesis induced by vascular endothelial growth factor and basic fibroblast growth factor. Angiogenesis (2007) 0.95
Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism. Am J Physiol Cell Physiol (2008) 0.94
Role of the proteolytic hierarchy between cathepsin L, cathepsin D and caspase-3 in regulation of cellular susceptibility to apoptosis and autophagy. Biochim Biophys Acta (2008) 0.92
Post-transplant Burkitt lymphoma is a more aggressive and distinct form of post-transplant lymphoproliferative disorder. Cancer (2011) 0.90
Bilateral prepubertal testicular biopsies predict significance of cryptorchidism-associated mixed testicular atrophy, and allow assessment of fertility. Am J Surg Pathol (2007) 0.89
Juvenile hyaline fibromatosis and infantile systemic hyalinosis overlap associated with a novel mutation in capillary morphogenesis protein-2 gene. Am J Dermatopathol (2007) 0.87
Sclerosing stromal tumor: an important differential diagnosis of ovarian neoplasms in childhood and adolescence. Pediatr Dev Pathol (2009) 0.86
Clear cell adenocarcinoma of the cervix in a child without in utero exposure to diethylstilbestrol: a case report and review of the literature. Pediatr Dev Pathol (2005) 0.85
The potentially lethal nature of bronchial casts: plastic bronchitis. Int J Surg Pathol (2008) 0.83
Congenital fibrosarcoma with a novel complex 3-way translocation t(12;15;19) and unusual histologic features. Hum Pathol (2008) 0.83
Renal cell carcinoma with t(X;17): singular pediatric neoplasm with specific phenotype/genotype features. Pediatr Dev Pathol (2002) 0.82
Lethal outcomes in Klippel-Trenaunay syndrome. Pediatr Dev Pathol (2013) 0.82
Role of the beta catenin destruction complex in mediating chemotherapy-induced senescence-associated secretory phenotype. PLoS One (2012) 0.82
Doxorubicin resistant neuroblastoma cells secrete factors that activate AKT and attenuate cytotoxicity in drug-sensitive cells. Cancer Lett (2002) 0.81
Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions. Aging (Albany NY) (2009) 0.81
Cellular conditioning with trichostatin A enhances the anti-stress response through up-regulation of HDAC4 and down-regulation of the IGF/Akt pathway. Aging Cell (2008) 0.80
Perinatal onset mevalonate kinase deficiency. Pediatr Dev Pathol (2011) 0.79
Life-threatening blood loss from scratching provoked by pruritus in the bulky perineal nevocytoma variant of giant congenital melanocytic nevus in a child. J Am Acad Dermatol (2005) 0.79
Heterotopic nephrogenic rests in the colon and multiple congenital anomalies: possibly related association. Pediatr Dev Pathol (2002) 0.79
Chronic granulomatous disease. Pediatr Dev Pathol (2004) 0.79
Expanding the clinical spectrum of Frasier syndrome. Pediatr Dev Pathol (2007) 0.78
NRAS Status in Giant Melanocytic Nevus With Metastatic Melanoma. Am J Dermatopathol (2016) 0.77
Stress resistant human embryonic stem cells as a potential source for the identification of novel cancer stem cell markers. Cancer Lett (2009) 0.77
Acinar cell carcinoma versus solid pseudopapillary tumor of the pancreas in children: a comparison of two rare and overlapping entities with review of the literature. Pediatr Dev Pathol (2008) 0.77
Gaucher or pseudo-Gaucher? The challenge of several diseases colliding in a pediatric patient. Hum Pathol (2008) 0.77
Hormonal activity may predict aggressive behavior in neuroblastoma. Pediatr Dev Pathol (2002) 0.77
Expression of epidermal growth factor receptor, but not K-RAS mutations, is present in congenital cystic airway malformation/congenital pulmonary airway malformation. Hum Pathol (2007) 0.77
Pediatric chronic sclerosing sialadenitis: Küttner tumor. Pediatr Dev Pathol (2011) 0.77
Perspectives in pediatric pathology, chapter 3. Testicular development from birth to puberty: systematic evaluation of the prepubertal testis. Pediatr Dev Pathol (2014) 0.76
Clear cell sarcoma of the kidney in a child with Fanconi anemia. Pediatr Dev Pathol (2014) 0.76
Rapid progression of SETTLE tumor with micrometastasis. Pediatr Dev Pathol (2008) 0.75
Utility of C4d immunostaining in the first year after pediatric and young adult heart transplantation. J Heart Lung Transplant (2013) 0.75
Edvard Munch and placental pathology. Pediatr Dev Pathol (2011) 0.75
Ureteral ectopia inserting into ipsilateral epididymis resulting in inflammatory paratesticular tumor. Urology (2012) 0.75
Metastatic peritoneal neurocutaneous melanocytosis. Am J Surg Pathol (2008) 0.75
Images in pathology. Sickle cell disease. Int J Surg Pathol (2008) 0.75
Morphologic Spectrum of Rhabdomyomatous Mesenchymal Hamartomas (Striated Muscle Hamartomas) in Pediatric Dermatopathology. Am J Dermatopathol (2022) 0.75
The spectrum of persistence of testicular blastema and ectopic testicular parenchyma: a possible result of focal delay in gonadal development. Virchows Arch (2007) 0.75
Perspectives in pediatric pathology, chapter 1. Normal development of testicular structures: from the bipotential gonad to the fetal testis. Pediatr Dev Pathol (2014) 0.75
Actinomycotic mastoiditis complicated by sigmoid sinus thrombosis and labyrinthine fistula. Pediatr Dev Pathol (2014) 0.75
Phenotype and immunophenotype of the most common pediatric tumors. Appl Immunohistochem Mol Morphol (2015) 0.75
Perspectives in pediatric pathology: chapter 2. Testicular descent. Pediatr Dev Pathol (2014) 0.75
Defining the transition zone of Hirschsprung disease. Pediatr Dev Pathol (2013) 0.75
Extranodal marginal zone B-cell lymphoma/maltoma of the lip in a child: case report and review of cutaneous lymphoid proliferations in childhood. Int J Surg Pathol (2006) 0.75
Fetal gonadoblastoid testicular dysplasia: a focal failure of testicular development. Pediatr Dev Pathol (2007) 0.75
Renal medullary dysplasia is diagnostic of Beckwith-Wiedemann syndrome. Int J Surg Pathol (2007) 0.75
Relaunching the "Current Practice in Pediatric Pathology" section. Pediatr Dev Pathol (2008) 0.75
Penoscrotal edema and purpura in a 12-year-old boy: a case report and review of causes. J Pediatr Urol (2012) 0.75
Skin of patients with large/giant congenital melanocytic nevi shows increased mast cells. Pediatr Dev Pathol (2014) 0.75
Idiopathic intervertebral disc calcification in childhood: an atypical case of an uncommon entity for pediatric pathologists. Pediatr Dev Pathol (2013) 0.75
Neurocutaneous melanosis is associated with tethered spinal cord. Childs Nerv Syst (2014) 0.75
Pulmonary squamous cell carcinoma associated with repaired congenital tracheoesophageal fistula and esophageal atresia. Pediatr Pulmonol (2010) 0.75
Autosomal recessive polycystic kidney disease associated with nephrogenic rests: a possible consequence of arrested renal maturation. Pediatr Dev Pathol (2010) 0.75
Perspectives in pediatric pathology, chapter 4. Pubertal and adult testis. Pediatr Dev Pathol (2015) 0.75