Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.

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Published in Cancer Res on May 17, 2013

Authors

Sarah-Maria Fendt1, Eric L Bell, Mark A Keibler, Shawn M Davidson, Gregory J Wirth, Brian Fiske, Jared R Mayers, Matthias Schwab, Gary Bellinger, Alfredo Csibi, Akash Patnaik, Marie Jose Blouin, Lewis C Cantley, Leonard Guarente, John Blenis, Michael N Pollak, Aria F Olumi, Matthew G Vander Heiden, Gregory Stephanopoulos

Author Affiliations

1: Departments of Chemical Engineering and Biology, Massachusetts Institute of Technology, Cambridge, MA02139, USA.

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