Published in Front Endocrinol (Lausanne) on May 21, 2013
Pituitary adenylate cyclase activating polypeptide in stress-related disorders: data convergence from animal and human studies. Biol Psychiatry (2014) 0.87
Role of developmental factors in hypothalamic function. Front Neuroanat (2015) 0.87
PACAP receptor pharmacology and agonist bias: analysis in primary neurons and glia from the trigeminal ganglia and transfected cells. Br J Pharmacol (2014) 0.82
Convergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylate cyclase-activating polypeptide. Neuropharmacology (2015) 0.78
Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide, and their receptors and cancer. Curr Opin Endocrinol Diabetes Obes (2016) 0.75
PACAP and its receptors in migraine pathophysiology: Commentary on Walker et al., Br J Pharmacol 171: 1521-1533. Br J Pharmacol (2015) 0.75
PACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb. J Neurophysiol (2014) 0.75
Conformational Transitions of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor, a Human Class B GPCR. Sci Rep (2017) 0.75
Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem (2003) 21.11
Seven-transmembrane receptors. Nat Rev Mol Cell Biol (2002) 11.50
Calcium signaling. Cell (2007) 11.09
Diversity of G proteins in signal transduction. Science (1991) 7.41
Nova regulates brain-specific splicing to shape the synapse. Nat Genet (2005) 6.58
Heterotrimeric G protein activation by G-protein-coupled receptors. Nat Rev Mol Cell Biol (2008) 5.30
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature (2011) 4.94
Calcium regulation of neuronal gene expression. Proc Natl Acad Sci U S A (2001) 4.31
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes Dev (2008) 4.24
Differential signal transduction by five splice variants of the PACAP receptor. Nature (1993) 3.38
Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev (2009) 3.22
Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem Biophys Res Commun (1989) 3.03
Alternative splicing events identified in human embryonic stem cells and neural progenitors. PLoS Comput Biol (2007) 2.71
Fine-tuning of GPCR activity by receptor-interacting proteins. Nat Rev Mol Cell Biol (2009) 2.39
Seven transmembrane receptors: something old, something new. Acta Physiol (Oxf) (2007) 2.25
Translational control of intron splicing in eukaryotes. Nature (2008) 2.15
Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron (2010) 2.08
Deep brain photoreceptors control light-seeking behavior in zebrafish larvae. Curr Biol (2012) 2.05
Tissue-specific splicing of disordered segments that embed binding motifs rewires protein interaction networks. Mol Cell (2012) 2.02
An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons. Genes Dev (2009) 1.88
Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse. Genomics (2006) 1.80
Heterotrimeric G-proteins: a short history. Br J Pharmacol (2006) 1.79
Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins. Br J Pharmacol (2012) 1.69
Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous systems. Jpn J Physiol (1998) 1.67
VPAC and PAC receptors: From ligands to function. Pharmacol Ther (2008) 1.65
Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. Proc Natl Acad Sci U S A (2005) 1.65
Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1. Br J Pharmacol (2012) 1.64
Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway. J Neurosci (1997) 1.58
Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development. Curr Biol (2007) 1.58
PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nat Neurosci (2012) 1.58
The role of Rho in G protein-coupled receptor signal transduction. Annu Rev Pharmacol Toxicol (2000) 1.57
Calcium regulation of gene expression in neuronal cells. J Neurobiol (1994) 1.57
Target areas innervated by PACAP-immunoreactive retinal ganglion cells. Cell Tissue Res (2004) 1.51
Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene. Genes Dev (1999) 1.50
Depolarization and CaM kinase IV modulate NMDA receptor splicing through two essential RNA elements. PLoS Biol (2007) 1.49
A novel cyclic AMP-dependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation. Mol Cell Biol (2006) 1.45
Exon silencing by UAGG motifs in response to neuronal excitation. PLoS Biol (2007) 1.43
Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons. Proc Natl Acad Sci U S A (2007) 1.40
Roles for pituitary adenylate cyclase-activating peptide (PACAP) expression and signaling in the bed nucleus of the stria terminalis (BNST) in mediating the behavioral consequences of chronic stress. J Mol Neurosci (2010) 1.36
Pituitary adenylate cyclase-activating polypeptides directly stimulate sympathetic neuron neuropeptide Y release through PAC(1) receptor isoform activation of specific intracellular signaling pathways. J Biol Chem (1999) 1.33
Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi. FEMS Microbiol Rev (2008) 1.33
Fear extinction and BDNF: translating animal models of PTSD to the clinic. Genes Brain Behav (2012) 1.31
The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. Dev Biol (2000) 1.30
Pituitary adenylate cyclase-activating polypeptide (PACAP) mimics neuroendocrine and behavioral manifestations of stress: Evidence for PKA-mediated expression of the corticotropin-releasing hormone (CRH) gene. Brain Res Mol Brain Res (2005) 1.23
Stress hormone synthesis in mouse hypothalamus and adrenal gland triggered by restraint is dependent on pituitary adenylate cyclase-activating polypeptide signaling. Neuroscience (2009) 1.21
A novel spliced variant of the type 1 corticotropin-releasing hormone receptor with a deletion in the seventh transmembrane domain present in the human pregnant term myometrium and fetal membranes. Mol Endocrinol (1999) 1.21
Regulation of PC12 cell differentiation by cAMP signaling to ERK independent of PKA: do all the connections add up? Sci STKE (2007) 1.19
The neurotrophic effects of PACAP in PC12 cells: control by multiple transduction pathways. J Neurochem (2006) 1.14
Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia. Development (2007) 1.14
Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration. Dev Neurosci (2002) 1.12
PAC1 receptor (ADCYAP1R1) genotype is associated with dark-enhanced startle in children. Mol Psychiatry (2012) 1.12
Functions and regulatory mechanisms of Gq-signaling pathways. Neurosignals (2009) 1.10
Signal transduction in gastrointestinal smooth muscle. Cell Signal (1997) 1.08
Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2. RNA (2011) 1.08
The Secretin GPCRs descended from the family of Adhesion GPCRs. Mol Biol Evol (2008) 1.07
Neurotrophic effects of PACAP in the cerebellar cortex. Peptides (2007) 1.07
The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein. FASEB J (2006) 1.07
Physiological markers of anxiety are increased in children of abused mothers. J Child Psychol Psychiatry (2011) 1.06
Pattern of intra-family hetero-oligomerization involving the G-protein-coupled secretin receptor. J Mol Neurosci (2008) 1.05
Measuring thigmotaxis in larval zebrafish. Behav Brain Res (2011) 1.05
RAMPs: 5 years on, where to now? Trends Pharmacol Sci (2003) 1.04
VIP-PACAP system in immunity: new insights for multitarget therapy. Ann N Y Acad Sci (2006) 1.03
Patterns of avoidance behaviours in the light/dark preference test in young juvenile zebrafish: a pharmacological study. Behav Brain Res (2011) 1.03
Emerging Roles of Alternative Pre-mRNA Splicing Regulation in Neuronal Development and Function. Front Neurosci (2012) 1.02
Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress. Neuron (2012) 1.02
PACAP and NGF regulate common and distinct traits of the sympathoadrenal lineage: effects on electrical properties, gene markers and transcription factors in differentiating PC12 cells. Eur J Neurosci (2003) 1.01
Pituitary adenylate cyclase activating polypeptide protects dopaminergic neurons and improves behavioral deficits in a rat model of Parkinson's disease. Behav Brain Res (2004) 1.01
A role for SC35 and hnRNPA1 in the determination of amyloid precursor protein isoforms. Mol Psychiatry (2007) 1.01
Time-dependent effects of the neuropeptide PACAP on catecholamine secretion : stimulation and desensitization. Hypertension (1999) 1.01
Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice. FASEB J (2011) 1.00
N-terminal splice variants of the type I PACAP receptor: isolation, characterization and ligand binding/selectivity determinants. J Neuroendocrinol (1999) 1.00
CRF1 receptor splicing in epidermal keratinocytes: potential biological role and environmental regulations. J Cell Physiol (2009) 1.00
PACAP centrally mediates emotional stress-induced corticosterone responses in mice. Stress (2011) 0.98
The structure of secretin family GPCR peptide ligands: implications for receptor pharmacology and drug development. Drug Discov Today (2012) 0.98
Signaling through the neuropeptide GPCR PAC₁ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor. FASEB J (2012) 0.98
GPCR mediated regulation of synaptic transmission. Prog Neurobiol (2012) 0.98
Neuropeptides and neuropeptide receptors: drug targets, and peptide and non-peptide ligands: a tribute to Prof. Dieter Seebach. Chem Biodivers (2012) 0.97
Is PACAP the major neurotransmitter for stress transduction at the adrenomedullary synapse? J Mol Neurosci (2012) 0.97
Emerging role of alternative splicing of CRF1 receptor in CRF signaling. Acta Biochim Pol (2010) 0.97
Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system. Neuropsychopharmacology (2008) 0.96
Regulation of neuroblast mitosis is determined by PACAP receptor isoform expression. Proc Natl Acad Sci U S A (2001) 0.96
The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for pituitary adenylate cyclase-activating polypeptide-evoked neurosecretion. J Biol Chem (2007) 0.95
Characterization of novel splice variants of the PAC1 receptor in human neuroblastoma cells: consequences for signaling by VIP and PACAP. Mol Cell Neurosci (2005) 0.95
PACAP/PAC1 autocrine system promotes proliferation and astrogenesis in neural progenitor cells. Glia (2007) 0.94
The PACAP receptor: generation by alternative splicing of functional diversity among G protein-coupled receptors in nerve cells. Semin Cell Biol (1994) 0.92
Activation of α-secretase cleavage. J Neurochem (2011) 0.92
Molecular cloning of a novel variant of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor that stimulates calcium influx by activation of L-type calcium channels. J Biol Chem (1996) 0.92
Pituitary adenylate cyclase activating polypeptide and PAC1 receptor signaling increase Homer 1a expression in central and peripheral neurons. Regul Pept (2004) 0.91
Additional signals from VPAC/PAC family receptors. Biochem Soc Trans (2002) 0.91
Focus on the splicing of secretin GPCRs transmembrane-domain 7. Trends Biochem Sci (2009) 0.91
Autocrine expression and ontogenetic functions of the PACAP ligand/receptor system during sympathetic development. Dev Biol (2000) 0.91
Differential intracellular signaling through PAC1 isoforms as a result of alternative splicing in the first extracellular domain and the third intracellular loop. Mol Pharmacol (2007) 0.90
Development of the zebrafish hypothalamus. Ann N Y Acad Sci (2011) 0.90
The family B1 GPCR: structural aspects and interaction with accessory proteins. Curr Drug Targets (2012) 0.90
Structural determinants critical for localization and signaling within the seventh transmembrane domain of the type 1 corticotropin releasing hormone receptor: lessons from the receptor variant R1d. Mol Endocrinol (2008) 0.89
Molecular and cell signaling targets for PTSD pathophysiology and pharmacotherapy. Neuropharmacology (2011) 0.88
Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition. J Neurosci (2004) 2.38
The hypothalamic neuropeptide oxytocin is required for formation of the neurovascular interface of the pituitary. Dev Cell (2011) 1.46
Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia. Development (2007) 1.14
Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress. Neuron (2012) 1.02
Dopaminergic neuronal cluster size is determined during early forebrain patterning. Development (2008) 0.91
The metabolic regulator PGC-1α directly controls the expression of the hypothalamic neuropeptide oxytocin. J Neurosci (2011) 0.90
Development of the zebrafish hypothalamus. Ann N Y Acad Sci (2011) 0.90
High resolution fate map of the zebrafish diencephalon. Dev Dyn (2009) 0.89
Nasal embryonic LHRH factor plays a role in the developmental migration and projection of gonadotropin-releasing hormone 3 neurons in zebrafish. Dev Dyn (2009) 0.88
Neural protein Olig2 acts upstream of the transcriptional regulator Sim1 to specify diencephalic dopaminergic neurons. Dev Dyn (2009) 0.87
Cxcl12a-Cxcr4b signaling is important for proper development of the forebrain GnRH system in zebrafish. Gen Comp Endocrinol (2009) 0.82
Visualization of mRNA expression in the zebrafish embryo. Methods Mol Biol (2011) 0.82
Two-photon-based photoactivation in live zebrafish embryos. J Vis Exp (2010) 0.78
The not-so-long history of zebrafish research in Israel. Int J Dev Biol (2017) 0.75
The neurohypophysis: fishing for new insights. J Neuroendocrinol (2012) 0.75