Published in Diabetes on July 01, 2013
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BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol (2004) 6.72
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Epidemiological evidence for the links between sleep, circadian rhythms and metabolism. Obes Rev (2009) 1.83
CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function. Proc Natl Acad Sci U S A (2010) 1.63
FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis. Am J Physiol Endocrinol Metab (2002) 1.33
Circadian regulation of lipid mobilization in white adipose tissues. Diabetes (2013) 1.09
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A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med (2003) 9.23
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Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci U S A (2004) 4.60
Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes (2007) 4.28
Aging, adiposity, and calorie restriction. JAMA (2007) 3.95
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A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature (2012) 3.35
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Long-term caloric restriction ameliorates the decline in diastolic function in humans. J Am Coll Cardiol (2006) 3.29
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Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. Aging Cell (2008) 2.87
Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults. Am J Clin Nutr (2006) 2.76
Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women. Circulation (2004) 2.73
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Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial. Am J Clin Nutr (2006) 2.57
Energy balance and its components: implications for body weight regulation. Am J Clin Nutr (2012) 2.51
Bone mineral density response to caloric restriction-induced weight loss or exercise-induced weight loss: a randomized controlled trial. Arch Intern Med (2006) 2.37
One year of caloric restriction in humans: feasibility and effects on body composition and abdominal adipose tissue. J Gerontol A Biol Sci Med Sci (2006) 2.31
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology (2007) 2.29
Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects. Diabetes (2013) 2.25
Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring) (2010) 2.25
Alterations in ventricular structure and function in obese adolescents with nonalcoholic fatty liver disease. J Pediatr (2012) 2.23
Gastric bypass and banding equally improve insulin sensitivity and β cell function. J Clin Invest (2012) 2.19
Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction. Gastroenterology (2009) 2.19
Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes (2010) 2.10
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet (2008) 1.98
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake. Cell Metab (2008) 1.94
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance. Cell Metab (2012) 1.93
Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial. Am J Physiol Endocrinol Metab (2007) 1.85
Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk. Am J Clin Nutr (2006) 1.75
Lower extremity muscle size and strength and aerobic capacity decrease with caloric restriction but not with exercise-induced weight loss. J Appl Physiol (1985) (2006) 1.68
Use of stable isotopically labeled tracers to measure very low density lipoprotein-triglyceride turnover. J Lipid Res (2002) 1.67
Extreme obesity: a new medical crisis in the United States. Mayo Clin Proc (2006) 1.66
Effect of long-term calorie restriction with adequate protein and micronutrients on thyroid hormones. J Clin Endocrinol Metab (2006) 1.64
Metabolic effects of treatment with atypical antipsychotics. J Clin Psychiatry (2004) 1.63
Sucralose affects glycemic and hormonal responses to an oral glucose load. Diabetes Care (2013) 1.63
Surgical removal of omental fat does not improve insulin sensitivity and cardiovascular risk factors in obese adults. Gastroenterology (2010) 1.62
Energy expenditure, sex, and endogenous fuel availability in humans. J Clin Invest (2003) 1.62
The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res (2011) 1.60
Bariatric surgery and cardiovascular risk factors: a scientific statement from the American Heart Association. Circulation (2011) 1.59
Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production. Age (Dordr) (2009) 1.57
Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. Gastroenterology (2013) 1.57
What does the measurement of whole-body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean? Diabetes (2003) 1.56
Assessment of intrahepatic triglyceride content using magnetic resonance spectroscopy. J Cardiometab Syndr (2007) 1.55
A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity. Obes Res (2003) 1.48
Effect of sex and obesity on basal VLDL-triacylglycerol kinetics. Am J Clin Nutr (2003) 1.48
Hepatic lipin 1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss. Diabetes (2007) 1.47
Weight loss induced by Roux-en-Y gastric bypass but not laparoscopic adjustable gastric banding increases circulating bile acids. J Clin Endocrinol Metab (2013) 1.45
Nonalcoholic fatty liver disease is associated with hepatic and skeletal muscle insulin resistance in overweight adolescents. Am J Clin Nutr (2008) 1.44
Effect of weight loss and exercise therapy on bone metabolism and mass in obese older adults: a one-year randomized controlled trial. J Clin Endocrinol Metab (2008) 1.41
Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile. Hum Mol Genet (2010) 1.40
Celiac disease unmasked after pancreaticoduodenectomy. JPEN J Parenter Enteral Nutr (2005) 1.39
Relationship between body fat mass and free fatty acid kinetics in men and women. Obesity (Silver Spring) (2009) 1.37
Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: A 1-year randomized controlled trial. Diabetes Care (2002) 1.35
Effect of weight loss on VLDL-triglyceride and apoB-100 kinetics in women with abdominal obesity. Am J Physiol Endocrinol Metab (2002) 1.34
Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. Obesity (Silver Spring) (2009) 1.33
Effects of bariatric surgery on glucose homeostasis and type 2 diabetes. Gastroenterology (2012) 1.33
Women produce fewer but triglyceride-richer very low-density lipoproteins than men. J Clin Endocrinol Metab (2007) 1.31
Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects. Gastroenterology (2012) 1.27
Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia. Gastroenterology (2010) 1.27
Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content. Obesity (Silver Spring) (2008) 1.27
Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes. Diabetes (2006) 1.25
Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease. J Clin Endocrinol Metab (2010) 1.21
Multiorgan insulin sensitivity in lean and obese subjects. Diabetes Care (2012) 1.20
Weight loss therapy improves pancreatic endocrine function in obese older adults. Obesity (Silver Spring) (2008) 1.18
Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease. Hepatology (2012) 1.18
Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin. Diabetes Care (2002) 1.18
Effect of gender on lipid kinetics during endurance exercise of moderate intensity in untrained subjects. Am J Physiol Endocrinol Metab (2002) 1.18
Effect of moderate diet-induced weight loss and weight regain on cardiovascular structure and function. J Am Coll Cardiol (2009) 1.17
Metabolically normal obese people are protected from adverse effects following weight gain. J Clin Invest (2015) 1.17
Nocturnal and postprandial free fatty acid kinetics in normal and type 2 diabetic subjects: effects of insulin sensitization therapy. Diabetes (2003) 1.15
VLDL-triglyceride kinetics during hyperglycemia-hyperinsulinemia: effects of sex and obesity. Am J Physiol Endocrinol Metab (2002) 1.15
Weight loss reduces liver fat and improves hepatic and skeletal muscle insulin sensitivity in obese adolescents. Obesity (Silver Spring) (2009) 1.14
Increased whole-body adiposity without a concomitant increase in liver fat is not associated with augmented metabolic dysfunction. Obesity (Silver Spring) (2010) 1.14
Pathogenesis and pathophysiology of the cardiometabolic syndrome. J Clin Hypertens (Greenwich) (2009) 1.14
Whole-body proteolysis rate is elevated in HIV-associated insulin resistance. Diabetes (2006) 1.14
A comparison of D2 receptor specific binding in obese and normal-weight individuals using PET with (N-[(11)C]methyl)benperidol. Synapse (2013) 1.07
Comparative effects of low-carbohydrate high-protein versus low-fat diets on the kidney. Clin J Am Soc Nephrol (2012) 1.06
Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism. Diabetes (2013) 1.05
Regional muscle and adipose tissue amino acid metabolism in lean and obese women. Am J Physiol Endocrinol Metab (2002) 1.05
Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver. J Lipid Res (2012) 1.05
Relationship between treatment preference and weight loss in the context of a randomized controlled trial. Obesity (Silver Spring) (2011) 1.04
Recombinant human leptin treatment does not improve insulin action in obese subjects with type 2 diabetes. Diabetes (2011) 1.03
Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk. Rejuvenation Res (2007) 1.02
Changes in taste perception and eating behavior after bariatric surgery-induced weight loss in women. Obesity (Silver Spring) (2013) 1.02
Implantable gastric stimulation for the treatment of clinically severe obesity: results of the SHAPE trial. Surg Obes Relat Dis (2008) 1.00
Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy. Metabolism (2005) 1.00
Reproducibility of postprandial lipemia tests and validity of an abbreviated 4-hour test. Metabolism (2008) 0.99
Bariatric surgery-induced weight loss causes remission of food addiction in extreme obesity. Obesity (Silver Spring) (2014) 0.98
Ginseng and ginsenoside Re do not improve β-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes. Diabetes Care (2011) 0.97
Adipose tissue, hepatic, and skeletal muscle insulin sensitivity in extremely obese subjects with acanthosis nigricans. Metabolism (2006) 0.96
Insulin sensitivity is not associated with palmitoleate availability in obese humans. J Lipid Res (2011) 0.95