Published in Hum Mol Genet on October 08, 2010
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages. Nat Immunol (2014) 1.79
Role of the gut in lipid homeostasis. Physiol Rev (2012) 1.73
The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res (2011) 1.60
Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. Am J Hum Genet (2012) 1.60
Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation. Kidney Int (2016) 1.39
Platelet CD36 surface expression levels affect functional responses to oxidized LDL and are associated with inheritance of specific genetic polymorphisms. Blood (2011) 1.32
Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. Am J Hum Genet (2013) 1.27
CD36 protein is involved in store-operated calcium flux, phospholipase A2 activation, and production of prostaglandin E2. J Biol Chem (2011) 1.17
CD36 genetics and the metabolic complications of obesity. Curr Opin Clin Nutr Metab Care (2011) 1.08
Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism. Annu Rev Nutr (2014) 1.06
CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin. FASEB J (2012) 0.99
CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting. J Biol Chem (2012) 0.98
Obesity alters the gustatory perception of lipids in the mouse: plausible involvement of lingual CD36. J Lipid Res (2013) 0.95
The origin of circulating CD36 in type 2 diabetes. Nutr Diabetes (2013) 0.94
Pathway-based genome-wide association analysis of coronary heart disease identifies biologically important gene sets. Eur J Hum Genet (2012) 0.93
Lipid-mediated release of GLP-1 by mouse taste buds from circumvallate papillae: putative involvement of GPR120 and impact on taste sensitivity. J Lipid Res (2012) 0.92
CD36 deletion reduces VLDL secretion, modulates liver prostaglandins, and exacerbates hepatic steatosis in ob/ob mice. J Lipid Res (2013) 0.89
Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans. Obesity (Silver Spring) (2012) 0.86
Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans. Hum Genet (2014) 0.82
Positive association of CD36 gene variants with the visual outcome of photodynamic therapy in polypoidal choroidal vasculopathy. Mol Vis (2012) 0.80
The oral lipid sensor GPR120 is not indispensable for the orosensory detection of dietary lipids in mice. J Lipid Res (2014) 0.80
The association of CD36 variants with polypoidal choroidal vasculopathy compared to typical neovascular age-related macular degeneration. Mol Vis (2012) 0.79
Adipose and muscle tissue profile of CD36 transcripts in obese subjects highlights the role of CD36 in fatty acid homeostasis and insulin resistance. Diabetes Care (2014) 0.79
CD36 actions in the heart: Lipids, calcium, inflammation, repair and more? Biochim Biophys Acta (2016) 0.78
Dietary Lipids Inform the Gut and Brain about Meal Arrival via CD36-Mediated Signal Transduction. J Nutr (2015) 0.78
CD36-deficient congenic strains show improved glucose tolerance and distinct shifts in metabolic and transcriptomic profiles. Heredity (Edinb) (2012) 0.78
CD36 deficiency impairs the small intestinal barrier and induces subclinical inflammation in mice. Cell Mol Gastroenterol Hepatol (2017) 0.78
CD36 haplotypes are associated with lipid profile in normal-weight subjects. Lipids Health Dis (2013) 0.77
Parkin reinvents itself to regulate fatty acid metabolism by tagging CD36. J Clin Invest (2011) 0.77
The pathophysiology of intestinal lipoprotein production. Front Physiol (2015) 0.77
Pathogenesis and Prevention of Hepatic Steatosis. Gastroenterol Hepatol (N Y) (2015) 0.76
A Common CD36 Variant Influences Endothelial Function and Response to Treatment with Phosphodiesterase 5 Inhibition. J Clin Endocrinol Metab (2016) 0.76
Oral Fat Sensing and CD36 Gene Polymorphism in Algerian Lean and Obese Teenagers. Nutrients (2015) 0.76
Teaching an old dog new tricks: potential antiatherothrombotic use for statins. J Clin Invest (2012) 0.75
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Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat. Dis Model Mech (2017) 0.75
Variants of CD36 gene and their association with CD36 protein expression in platelets. Blood Transfus (2014) 0.75
CD36 genotype associated with ischemic stroke in Chinese Han. Int J Clin Exp Med (2015) 0.75
CD36 genetic variation, fat intake and liver fibrosis in chronic hepatitis C virus infection. World J Hepatol (2016) 0.75
Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36. J Lipid Res (2016) 0.75
Associations between CD36 gene polymorphisms, fat tolerance and oral fat preference in a young-adult population. Eur J Clin Nutr (2016) 0.75
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FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization. Nucleic Acids Res (2006) 5.60
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A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J Biol Chem (1999) 4.61
CD36 deficiency associated with insulin resistance. Lancet (2001) 3.82
CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior. Sci Signal (2009) 3.77
CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima. J Clin Invest (2008) 3.29
Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis. Pharmacol Rev (2006) 3.26
Mendelian randomisation and causal inference in observational epidemiology. PLoS Med (2008) 3.12
A CD36-dependent signaling cascade is necessary for macrophage foam cell formation. Cell Metab (2006) 3.06
Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome. Arterioscler Thromb Vasc Biol (2008) 2.96
CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions. J Clin Invest (2005) 2.81
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology (2007) 2.43
Gene expression in human NAFLD. Am J Physiol Gastrointest Liver Physiol (2008) 2.33
Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes (2007) 2.24
Factors of insulin resistance syndrome--related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic mexican-americans. Diabetes (2002) 2.06
Apolipoprotein E isoforms, serum cholesterol, and cancer. Lancet (1986) 2.05
CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. J Clin Invest (2005) 2.04
CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine. J Biol Chem (2007) 2.02
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet (2008) 1.98
CD36 and macrophages in atherosclerosis. Cardiovasc Res (2007) 1.85
Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux. J Lipid Res (2005) 1.83
Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways. J Lipid Res (2008) 1.80
Cellular fatty acid uptake: a pathway under construction. Trends Endocrinol Metab (2009) 1.70
CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine. Gastroenterology (2006) 1.67
Genetics of variation in HDL cholesterol in humans and mice. Circ Res (2005) 1.58
A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet (2004) 1.56
Genetic causes of high and low serum HDL-cholesterol. J Lipid Res (2010) 1.55
Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes. Hum Mol Genet (2009) 1.50
CD36 gene deletion reduces fat preference and intake but not post-oral fat conditioning in mice. Am J Physiol Regul Integr Comp Physiol (2007) 1.47
Identification of the oxidized low-density lipoprotein scavenger receptor CD36 in plasma: a novel marker of insulin resistance. Circulation (2006) 1.38
Physiological and pathological roles of a multi-ligand receptor CD36 in atherogenesis; insights from CD36-deficient patients. Mol Cell Biochem (2007) 1.33
Defect in human myocardial long-chain fatty acid uptake is caused by FAT/CD36 mutations. J Lipid Res (2001) 1.20
Inflammation, atherosclerosis, and arterial thrombosis: role of the scavenger receptor CD36. Cleve Clin J Med (2009) 1.18
Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study. BMC Med Genet (2009) 1.17
Impaired fat oxidation after a single high-fat meal in insulin-sensitive nondiabetic individuals with a family history of type 2 diabetes. Diabetes (2007) 1.13
Genome-wide linkage analysis of lipids in the Hypertension Genetic Epidemiology Network (HyperGEN) Blood Pressure Study. Arterioscler Thromb Vasc Biol (2001) 1.13
Apoptosis is associated with CD36/fatty acid translocase upregulation in non-alcoholic steatohepatitis. Liver Int (2010) 1.12
CD36 mediates long-chain fatty acid transport in human myocardium: complete myocardial accumulation defect of radiolabeled long-chain fatty acid analog in subjects with CD36 deficiency. Mol Cell Biochem (1999) 1.12
Meta-analysis of genome-wide linkage studies of quantitative lipid traits in families ascertained for type 2 diabetes. Diabetes (2007) 1.08
Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance. Diabet Med (2006) 1.07
Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction. Am Heart J (2007) 1.05
Alternative promoter usage of the membrane glycoprotein CD36. BMC Mol Biol (2006) 1.05
The value of HDL genetics. Curr Opin Lipidol (2008) 1.04
Genetic study of the CD36 gene in a French diabetic population. Diabetes Metab (2004) 1.02
A CD36 nonsense mutation associated with insulin resistance and familial type 2 diabetes. Hum Mutat (2004) 1.00
Variants of the CD36 gene and metabolic syndrome in Boston Puerto Rican adults. Atherosclerosis (2010) 0.98
Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels. Clin Genet (2006) 0.96
Lipid-induced insulin resistance is associated with increased monocyte expression of scavenger receptor CD36 and internalization of oxidized LDL. Obesity (Silver Spring) (2009) 0.95
Bivariate linkage analysis of the insulin resistance syndrome phenotypes on chromosome 7q. Hum Biol (2005) 0.95
Single-nucleotide polymorphism of CD36 locus and obesity in European adolescents. Obesity (Silver Spring) (2009) 0.95
CD36 does not play a direct role in HDL or LDL metabolism. J Lipid Res (2001) 0.94
CD36 gene promoter polymorphisms are associated with low density lipoprotein-cholesterol in normal twins and after a low-calorie diet in obese subjects. Twin Res Hum Genet (2008) 0.93
Phenotype-genotype correlation in CD36 deficiency types I and II. Thromb Haemost (2000) 0.93
Automated mass spectrometry: a revolutionary technology for clinical diagnostics. Mol Diagn (2000) 0.93
Lipid-lowering drugs in ischemic stroke prevention and their influence on acute stroke outcome. Cerebrovasc Dis (2009) 0.92
Polymorphisms in the CD36 gene modulate the ability of fish oil supplements to lower fasting plasma triacyl glycerol and raise HDL cholesterol concentrations in healthy middle-aged men. Prostaglandins Leukot Essent Fatty Acids (2008) 0.89
Optimization of beta-quantification methods for high-throughput applications. Clin Chem (2001) 0.89
Low levels of high density lipoprotein increase the severity of cerebral white matter changes: implications for prevention and treatment of cerebrovascular diseases. Curr Alzheimer Res (2010) 0.89
Increased CD36 expression signals monocyte activation among patients with type 2 diabetes. Diabetes Care (2010) 0.89
Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice. PLoS One (2010) 0.87
Variability of the CD36 gene in West Africa. Hum Mutat (2001) 0.87
Genomic heterogeneity of type II CD36 deficiency. Clin Chim Acta (2002) 0.86
CD36 polymorphism and its relationship with body mass index and coronary artery disease in a Korean population. Clin Chem Lab Med (2007) 0.85
Identification and structural comparison of deleterious mutations in nsSNPs of ABL1 gene in chronic myeloid leukemia: a bio-informatics study. J Biomed Inform (2007) 0.84
Lack of myocardial iodine-123 15-(p-iodiphenyl)-3-R,S-methylpentadecanoic acid (BMIPP) uptake and CD36 abnormality--CD36 deficiency and hypertrophic cardiomyopathy. Jpn Circ J (1997) 0.84
Platelet GPIbalpha, GPIV and vWF polymorphisms and fatal pre-hospital MI among middle-aged men. J Thromb Thrombolysis (2007) 0.83
Catabolism of lipoproteins and metabolic syndrome. Curr Opin Clin Nutr Metab Care (2009) 0.83
CD36 single nucleotide polymorphism is associated with variation in low-density lipoprotein-cholesterol in young Japanese men. Biomarkers (2009) 0.83
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Physical frailty and body composition in obese elderly men and women. Obes Res (2004) 4.61
Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci U S A (2004) 4.60
Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes (2007) 4.28
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Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet (2007) 3.58
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes (2008) 3.47
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Long-term caloric restriction ameliorates the decline in diastolic function in humans. J Am Coll Cardiol (2006) 3.29
Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology (2008) 3.04
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Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial. Am J Clin Nutr (2006) 2.57
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One year of caloric restriction in humans: feasibility and effects on body composition and abdominal adipose tissue. J Gerontol A Biol Sci Med Sci (2006) 2.31
Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice. J Clin Invest (2002) 2.30
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology (2007) 2.29
Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects. Diabetes (2013) 2.25
Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring) (2010) 2.25
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Gastric bypass and banding equally improve insulin sensitivity and β cell function. J Clin Invest (2012) 2.19
Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction. Gastroenterology (2009) 2.19
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Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes (2010) 2.10
CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. J Clin Invest (2005) 2.04
CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine. J Biol Chem (2007) 2.02
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet (2008) 1.98
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake. Cell Metab (2008) 1.94
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance. Cell Metab (2012) 1.93
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Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways. J Lipid Res (2008) 1.80
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Gastric bypass surgery improves metabolic and hepatic abnormalities associated with nonalcoholic fatty liver disease. Gastroenterology (2006) 1.75
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Lower extremity muscle size and strength and aerobic capacity decrease with caloric restriction but not with exercise-induced weight loss. J Appl Physiol (1985) (2006) 1.68
CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine. Gastroenterology (2006) 1.67
Use of stable isotopically labeled tracers to measure very low density lipoprotein-triglyceride turnover. J Lipid Res (2002) 1.67
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Sucralose affects glycemic and hormonal responses to an oral glucose load. Diabetes Care (2013) 1.63
Surgical removal of omental fat does not improve insulin sensitivity and cardiovascular risk factors in obese adults. Gastroenterology (2010) 1.62
Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling. J Clin Invest (2005) 1.62
Energy expenditure, sex, and endogenous fuel availability in humans. J Clin Invest (2003) 1.62
Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis. Diabetes (2008) 1.61
The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res (2011) 1.60
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What does the measurement of whole-body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean? Diabetes (2003) 1.56
A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet (2004) 1.56
Assessment of intrahepatic triglyceride content using magnetic resonance spectroscopy. J Cardiometab Syndr (2007) 1.55
Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype. J Biol Chem (2007) 1.53
Role of CD36 in membrane transport of long-chain fatty acids. Curr Opin Clin Nutr Metab Care (2002) 1.51
A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity. Obes Res (2003) 1.48
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Hepatic lipin 1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss. Diabetes (2007) 1.47
Weight loss induced by Roux-en-Y gastric bypass but not laparoscopic adjustable gastric banding increases circulating bile acids. J Clin Endocrinol Metab (2013) 1.45
Nonalcoholic fatty liver disease is associated with hepatic and skeletal muscle insulin resistance in overweight adolescents. Am J Clin Nutr (2008) 1.44
Fatty acid transport across membranes: relevance to nutrition and metabolic pathology. Annu Rev Nutr (2002) 1.42
CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. J Biol Chem (2008) 1.41
Effect of weight loss and exercise therapy on bone metabolism and mass in obese older adults: a one-year randomized controlled trial. J Clin Endocrinol Metab (2008) 1.41
Diacylglycerol enrichment of endoplasmic reticulum or lipid droplets recruits perilipin 3/TIP47 during lipid storage and mobilization. J Biol Chem (2009) 1.41
CD36-facilitated fatty acid uptake inhibits leptin production and signaling in adipose tissue. Diabetes (2007) 1.41
Celiac disease unmasked after pancreaticoduodenectomy. JPEN J Parenter Enteral Nutr (2005) 1.39
Relationship between body fat mass and free fatty acid kinetics in men and women. Obesity (Silver Spring) (2009) 1.37
Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: A 1-year randomized controlled trial. Diabetes Care (2002) 1.35
Effect of weight loss on VLDL-triglyceride and apoB-100 kinetics in women with abdominal obesity. Am J Physiol Endocrinol Metab (2002) 1.34
Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies. Diabetes (2008) 1.33
Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. Obesity (Silver Spring) (2009) 1.33
Effects of bariatric surgery on glucose homeostasis and type 2 diabetes. Gastroenterology (2012) 1.33
Women produce fewer but triglyceride-richer very low-density lipoproteins than men. J Clin Endocrinol Metab (2007) 1.31
Luminal lipid regulates CD36 levels and downstream signaling to stimulate chylomicron synthesis. J Biol Chem (2011) 1.30
Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects. Gastroenterology (2012) 1.27
Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia. Gastroenterology (2010) 1.27
Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content. Obesity (Silver Spring) (2008) 1.27
Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes. Diabetes (2006) 1.25