Published in Diabetes on July 01, 2003
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes (2008) 3.47
Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology (2008) 3.04
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology (2007) 2.29
Relationship between body fat mass and free fatty acid kinetics in men and women. Obesity (Silver Spring) (2009) 1.37
Improved insulin sensitivity after weight loss and exercise training is mediated by a reduction in plasma fatty acid mobilization, not enhanced oxidative capacity. J Physiol (2009) 1.31
Multiorgan insulin sensitivity in lean and obese subjects. Diabetes Care (2012) 1.20
Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease. Hepatology (2012) 1.18
Pathogenesis and pathophysiology of the cardiometabolic syndrome. J Clin Hypertens (Greenwich) (2009) 1.14
Storage rates of circulating free fatty acid into adipose tissue during eating or walking in humans. Diabetes (2012) 1.07
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity. Metabolism (2011) 1.00
A single session of low-intensity exercise is sufficient to enhance insulin sensitivity into the next day in obese adults. Diabetes Care (2013) 0.96
The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species. J Lipid Res (2011) 0.95
Diurnal variation in insulin sensitivity of glucose metabolism is associated with diurnal variations in whole-body and cellular fatty acid metabolism in metabolically normal women. J Clin Endocrinol Metab (2014) 0.95
Testosterone increases the muscle protein synthesis rate but does not affect very-low-density lipoprotein metabolism in obese premenopausal women. Am J Physiol Endocrinol Metab (2012) 0.92
Impaired plasma nonesterified fatty acid tolerance is an early defect in the natural history of type 2 diabetes. J Clin Endocrinol Metab (2008) 0.90
Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo. Clin Lipidol (2009) 0.89
Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects. PLoS One (2010) 0.86
Decrease in hepatic very-low-density lipoprotein-triglyceride secretion after weight loss is inversely associated with changes in circulating leptin. Diabetes Obes Metab (2010) 0.84
Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with Type 2 diabetes with and without fatty liver. Am J Physiol Gastrointest Liver Physiol (2014) 0.83
Estrogen deficiency after menopause does not result in male very-low-density lipoprotein metabolism phenotype. J Clin Endocrinol Metab (2010) 0.83
Association between plasma nonesterified fatty acids species and adipose tissue fatty acid composition. PLoS One (2013) 0.82
Fatty acid and very low density lipoprotein metabolism in obese African American and Caucasian women with type 2 diabetes. J Lipid Res (2012) 0.81
One day of mixed meal overfeeding reduces hepatic insulin sensitivity and increases VLDL particle but not VLDL-triglyceride secretion in overweight and obese men. J Clin Endocrinol Metab (2013) 0.81
Basal adipose tissue and hepatic lipid kinetics are not affected by a single exercise bout of moderate duration and intensity in sedentary women. Clin Sci (Lond) (2009) 0.81
A transient increase in lipid peroxidation primes preadipocytes for delayed mitochondrial inner membrane permeabilization and ATP depletion during prolonged exposure to fatty acids. Free Radic Biol Med (2013) 0.81
Low-dose dexamethasone administration for 3 weeks favorably affects plasma HDL concentration and composition but does not affect very low-density lipoprotein kinetics. Eur J Endocrinol (2012) 0.81
Insulin activation of plasma nonesterified fatty acid uptake in metabolic syndrome. Arterioscler Thromb Vasc Biol (2012) 0.80
Systemic delivery of estradiol, but not testosterone or progesterone, alters very low density lipoprotein-triglyceride kinetics in postmenopausal women. J Clin Endocrinol Metab (2014) 0.80
Mesenchymal Stem Cells Ameliorated Glucolipotoxicity in HUVECs through TSG-6. Int J Mol Sci (2016) 0.79
Kinetics of saturated, monounsaturated, and polyunsaturated fatty acids in humans. Diabetes (2012) 0.77
Cardiometabolic interventions - focus on transcriptional regulators. Eur J Cardiovasc Med (2013) 0.76
Notch-ligand expression by NALT dendritic cells regulates mucosal Th1- and Th2-type responses. Biochem Biophys Res Commun (2011) 0.76
Natural carbon isotope abundance of plasma metabolites and liver tissue differs between diabetic and non-diabetic Zucker diabetic fatty rats. PLoS One (2013) 0.76
High-Protein Intake during Weight Loss Therapy Eliminates the Weight-Loss-Induced Improvement in Insulin Action in Obese Postmenopausal Women. Cell Rep (2016) 0.76
VLDL Triglyceride Kinetics in Lean, Overweight, and Obese Men and Women. J Clin Endocrinol Metab (2016) 0.75
Lipoprotein kinetics in the metabolic syndrome: pathophysiological and therapeutic lessons from stable isotope studies. Clin Biochem Rev (2004) 0.75
Free fatty acid kinetics in the late phase of postexercise recovery: importance of resting fatty acid metabolism and exercise-induced energy deficit. Metabolism (2009) 0.75
Microbial ecology: human gut microbes associated with obesity. Nature (2006) 36.98
A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med (2003) 9.23
Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. N Engl J Med (2004) 6.12
Hyperglycemic crises in adult patients with diabetes. Diabetes Care (2009) 6.01
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proc Natl Acad Sci U S A (2009) 5.64
Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology (2010) 5.35
Physical frailty and body composition in obese elderly men and women. Obes Res (2004) 4.61
Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci U S A (2004) 4.60
Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes (2007) 4.28
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance. Sci Transl Med (2011) 4.07
Aging, adiposity, and calorie restriction. JAMA (2007) 3.95
Weight and metabolic outcomes after 2 years on a low-carbohydrate versus low-fat diet: a randomized trial. Ann Intern Med (2010) 3.73
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes (2008) 3.47
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature (2012) 3.35
Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Am J Clin Nutr (2005) 3.33
Long-term caloric restriction ameliorates the decline in diastolic function in humans. J Am Coll Cardiol (2006) 3.29
Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology (2008) 3.04
Metabolic and structural effects of phosphatidylcholine and deoxycholate injections on subcutaneous fat: a randomized, controlled trial. Aesthet Surg J (2013) 3.02
Assessing adiposity: a scientific statement from the American Heart Association. Circulation (2011) 3.00
Effect of weight loss and exercise on frailty in obese older adults. Arch Intern Med (2006) 2.94
Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. Aging Cell (2008) 2.87
Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults. Am J Clin Nutr (2006) 2.76
Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women. Circulation (2004) 2.73
Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Obes Res (2005) 2.72
Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial. Am J Clin Nutr (2006) 2.57
Energy balance and its components: implications for body weight regulation. Am J Clin Nutr (2012) 2.51
Bone mineral density response to caloric restriction-induced weight loss or exercise-induced weight loss: a randomized controlled trial. Arch Intern Med (2006) 2.37
One year of caloric restriction in humans: feasibility and effects on body composition and abdominal adipose tissue. J Gerontol A Biol Sci Med Sci (2006) 2.31
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology (2007) 2.29
Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects. Diabetes (2013) 2.25
Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring) (2010) 2.25
Alterations in ventricular structure and function in obese adolescents with nonalcoholic fatty liver disease. J Pediatr (2012) 2.23
Gastric bypass and banding equally improve insulin sensitivity and β cell function. J Clin Invest (2012) 2.19
Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction. Gastroenterology (2009) 2.19
Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes (2010) 2.10
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet (2008) 1.98
Fatty liver in familial hypobetalipoproteinemia: triglyceride assembly into VLDL particles is affected by the extent of hepatic steatosis. J Lipid Res (2002) 1.97
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake. Cell Metab (2008) 1.94
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance. Cell Metab (2012) 1.93
Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial. Am J Physiol Endocrinol Metab (2007) 1.85
TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes (2009) 1.83
Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk. Am J Clin Nutr (2006) 1.75
Effects of supplementation with essential amino acids on intrahepatic lipid concentrations during fructose overfeeding in humans. Am J Clin Nutr (2012) 1.71
Lower extremity muscle size and strength and aerobic capacity decrease with caloric restriction but not with exercise-induced weight loss. J Appl Physiol (1985) (2006) 1.68
Use of stable isotopically labeled tracers to measure very low density lipoprotein-triglyceride turnover. J Lipid Res (2002) 1.67
Extreme obesity: a new medical crisis in the United States. Mayo Clin Proc (2006) 1.66
Effect of long-term calorie restriction with adequate protein and micronutrients on thyroid hormones. J Clin Endocrinol Metab (2006) 1.64
Metabolic effects of treatment with atypical antipsychotics. J Clin Psychiatry (2004) 1.63
Sucralose affects glycemic and hormonal responses to an oral glucose load. Diabetes Care (2013) 1.63
Surgical removal of omental fat does not improve insulin sensitivity and cardiovascular risk factors in obese adults. Gastroenterology (2010) 1.62
Energy expenditure, sex, and endogenous fuel availability in humans. J Clin Invest (2003) 1.62
The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res (2011) 1.60
Bariatric surgery and cardiovascular risk factors: a scientific statement from the American Heart Association. Circulation (2011) 1.59
Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production. Age (Dordr) (2009) 1.57
Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. Gastroenterology (2013) 1.57
Assessment of intrahepatic triglyceride content using magnetic resonance spectroscopy. J Cardiometab Syndr (2007) 1.55
WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation. Cell Metab (2013) 1.51
Adrenal insufficiency in meningococcal sepsis: bioavailable cortisol levels and impact of interleukin-6 levels and intubation with etomidate on adrenal function and mortality. J Clin Endocrinol Metab (2005) 1.49
A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity. Obes Res (2003) 1.48
Effect of sex and obesity on basal VLDL-triacylglycerol kinetics. Am J Clin Nutr (2003) 1.48
Hepatic lipin 1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss. Diabetes (2007) 1.47
Effect of rectal distention on lower urinary tract function in children. J Urol (2010) 1.46
Weight loss induced by Roux-en-Y gastric bypass but not laparoscopic adjustable gastric banding increases circulating bile acids. J Clin Endocrinol Metab (2013) 1.45
Nonalcoholic fatty liver disease is associated with hepatic and skeletal muscle insulin resistance in overweight adolescents. Am J Clin Nutr (2008) 1.44
Effect of weight loss and exercise therapy on bone metabolism and mass in obese older adults: a one-year randomized controlled trial. J Clin Endocrinol Metab (2008) 1.41
Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile. Hum Mol Genet (2010) 1.40
Celiac disease unmasked after pancreaticoduodenectomy. JPEN J Parenter Enteral Nutr (2005) 1.39
METFORMIN: NONGLYCEMIC EFFECTS AND POTENTIAL NOVEL INDICATIONS. Endocr Pract (2016) 1.38
Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers. Sci Transl Med (2013) 1.38
Relationship between body fat mass and free fatty acid kinetics in men and women. Obesity (Silver Spring) (2009) 1.37
Reproducibility of stable isotope-labeled tracer measures of VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics. J Lipid Res (2007) 1.37
Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: A 1-year randomized controlled trial. Diabetes Care (2002) 1.35
Lipid metabolism response to a single, prolonged bout of endurance exercise in healthy young men. Am J Physiol Endocrinol Metab (2005) 1.34
Effect of weight loss on VLDL-triglyceride and apoB-100 kinetics in women with abdominal obesity. Am J Physiol Endocrinol Metab (2002) 1.34
Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. Obesity (Silver Spring) (2009) 1.33
Effects of bariatric surgery on glucose homeostasis and type 2 diabetes. Gastroenterology (2012) 1.33
Women produce fewer but triglyceride-richer very low-density lipoproteins than men. J Clin Endocrinol Metab (2007) 1.31
Rate of production of plasma and very-low-density lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensitivity. J Clin Endocrinol Metab (2004) 1.29
Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects. Gastroenterology (2012) 1.27
Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia. Gastroenterology (2010) 1.27
Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content. Obesity (Silver Spring) (2008) 1.27
Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes. Diabetes (2006) 1.25
Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance. Diabetes (2009) 1.24
Plasma free fatty acid storage in subcutaneous and visceral adipose tissue in postabsorptive women. Diabetes (2008) 1.22
Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease. J Clin Endocrinol Metab (2010) 1.21