Extraction protocol and mass spectrometry method for quantification of doxorubicin released locally from prodrugs in tumor tissue.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4110111)

Published in J Mass Spectrom on July 01, 2013

Authors

Stuart Ibsen1, Yongxuan Su, John Norton, Eran Zahavy, Tomoko Hayashi, Stephen Adams, Wolf Wrasidlo, Sadik Esener

Author Affiliations

1: Department of Bioengineering, Moores Cancer Center, University of California San Diego, 3855 Health Sciences Dr. # 0815, La Jolla, CA 92093-0815, USA. sibsen@ucsd.edu

Articles cited by this

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev (2004) 9.28

Doxorubicin-induced cardiomyopathy. N Engl J Med (1998) 9.08

Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer (2004) 7.91

Late mortality experience in five-year survivors of childhood and adolescent cancer: the Childhood Cancer Survivor Study. J Clin Oncol (2001) 4.56

Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J (1990) 2.41

Determination of doxorubicin levels in whole tumor and tumor nuclei in murine breast cancer tumors. Clin Cancer Res (2005) 1.81

Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: is surface coating with polyethylene glycol beneficial? Clin Cancer Res (1999) 1.54

Paclitaxel versus doxorubicin as first-line single-agent chemotherapy for metastatic breast cancer: a European Organization for Research and Treatment of Cancer Randomized Study with cross-over. J Clin Oncol (2000) 1.51

Bioactivation of self-immolative dendritic prodrugs by catalytic antibody 38C2. J Am Chem Soc (2004) 1.20

Prodrug strategies in cancer therapy. Eur J Med Chem (2001) 1.11

Tumor-activated prodrugs--a new approach to cancer therapy. Cancer Invest (2004) 1.09

First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: a phase I/II open-label and double-blind study. Eur J Cancer (2012) 1.08

Enzymatic activation of second-generation dendritic prodrugs: Conjugation of self-immolative dendrimers with poly(ethylene glycol) via click chemistry. Bioconjug Chem (2006) 1.00

Quantification of Doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopy. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.99

Epirubicin versus doxorubicin: which is the anthracycline of choice for the treatment of breast cancer? Clin Breast Cancer (2003) 0.94

A novel Doxorubicin prodrug with controllable photolysis activation for cancer chemotherapy. Pharm Res (2010) 0.94

Proton-mediated liberation of aldophosphamide from a nontoxic prodrug: a strategy for tumor-selective activation of cytocidal drugs. Cancer Res (1989) 0.93

Simple and sensitive quantification of anthracyclines in mouse atrial tissue using high-performance liquid chromatography and fluorescence detection. J Chromatogr (1991) 0.93

The antitumour activity of the prodrug N-L-leucyl-doxorubicin and its parent compound doxorubicin in human tumour xenografts. Eur J Cancer (1998) 0.89

High-performance liquid chromatographic validated assay of doxorubicin in rat plasma and tissues. J Chromatogr B Biomed Sci Appl (1999) 0.87

Simultaneous analysis of cyclophosphamide, doxorubicin and doxorubicinol by liquid chromatography coupled to tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.87

Localized in vivo activation of a photoactivatable doxorubicin prodrug in deep tumor tissue. Photochem Photobiol (2013) 0.84

Simultaneous high-performance liquid chromatographic determination of a glucuronyl prodrug of doxorubicin, doxorubicin and its metabolites in human lung tissue. J Chromatogr B Biomed Sci Appl (1998) 0.84

Doxorubicin cardiotoxicity in children: comparison of a consecutive divided daily dose administration schedule with single dose (rapid) infusion administration. Med Pediatr Oncol (1998) 0.84

Effect of cyclosporin A on the brain regional distribution of doxorubicin in rats. Int J Pharm (2007) 0.81

New method for the determination of doxorubicin, 4'-epidoxorubicin and all known metabolites in cardiac tissue. J Chromatogr (1988) 0.79

Development of magnetic multiwalled carbon nanotubes combined with near-infrared radiation-assisted desorption for the determination of tissue distribution of doxorubicin liposome injects in rats. J Chromatogr A (2011) 0.77

Articles by these authors

Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. Gastroenterology (2004) 6.47

Prospective multicenter study of the impact of the 21-gene recurrence score assay on medical oncologist and patient adjuvant breast cancer treatment selection. J Clin Oncol (2010) 4.81

Retracted Induction of a homeostatic circuit in lung tissue by microbial compounds. Immunity (2006) 2.49

Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis. Gastroenterology (2002) 2.19

IFN-alpha beta promote priming of antigen-specific CD8+ and CD4+ T lymphocytes by immunostimulatory DNA-based vaccines. J Immunol (2002) 1.30

Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand. Proc Natl Acad Sci U S A (2007) 1.28

Vaccination with irradiated Listeria induces protective T cell immunity. Immunity (2006) 1.23

Synthesis and immunological characterization of toll-like receptor 7 agonistic conjugates. Bioconjug Chem (2009) 1.20

Immunoprecipitation techniques for the analysis of transcription factor complexes. Methods (2002) 1.16

The involvement of IL-17A in the murine response to sub-lethal inhalational infection with Francisella tularensis. PLoS One (2010) 1.16

Airway peptidoglycan and immunostimulatory DNA exposures have divergent effects on the development of airway allergen hypersensitivities. J Allergy Clin Immunol (2004) 1.14

Half-antibody functionalized lipid-polymer hybrid nanoparticles for targeted drug delivery to carcinoembryonic antigen presenting pancreatic cancer cells. Mol Pharm (2010) 1.14

Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2010) 1.11

The course and variation of the facial artery and vein: implications for facial transplantation and facial surgery. Ann Plast Surg (2011) 1.10

Microbubble-mediated ultrasound therapy: a review of its potential in cancer treatment. Drug Des Devel Ther (2013) 1.10

Steroids initiate a signaling cascade that triggers rapid sporulation in Dictyostelium. Development (2009) 1.05

Successful eradication of a monoclonal strain of Klebsiella pneumoniae during a K. pneumoniae carbapenemase-producing K. pneumoniae outbreak in a surgical intensive care unit in Miami, Florida. Infect Control Hosp Epidemiol (2010) 1.02

Identification of substituted pyrimido[5,4-b]indoles as selective Toll-like receptor 4 ligands. J Med Chem (2013) 0.99

Acoustic droplet vaporization and propulsion of perfluorocarbon-loaded microbullets for targeted tissue penetration and deformation. Angew Chem Int Ed Engl (2012) 0.98

A novel nested liposome drug delivery vehicle capable of ultrasound triggered release of its payload. J Control Release (2011) 0.95

Magnetic resonance and fluorescence imaging of doxorubicin-loaded nanoparticles using a novel in vivo model. Nanomedicine (2010) 0.95

A novel Doxorubicin prodrug with controllable photolysis activation for cancer chemotherapy. Pharm Res (2010) 0.94

Role of IL-1 receptor-associated kinase-M (IRAK-M) in priming of immune and inflammatory responses by nitrogen bisphosphonates. Proc Natl Acad Sci U S A (2011) 0.93

A.S.P.E.N. parenteral nutrition safety consensus recommendations. JPEN J Parenter Enteral Nutr (2013) 0.92

Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction. PLoS One (2012) 0.92

Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains. Bioconjug Chem (2012) 0.91

Delivery of a peptide via poly(D,L-lactic-co-glycolic) acid nanoparticles enhances its dendritic cell-stimulatory capacity. Nanomedicine (2010) 0.91

Ultrasound mediated localized drug delivery. Adv Exp Med Biol (2012) 0.90

Analyses of the interaction of WRNIP1 with Werner syndrome protein (WRN) in vitro and in the cell. DNA Repair (Amst) (2006) 0.89

Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation. PLoS One (2013) 0.89

Induction of apoptosis by enediyne antibiotic calicheamicin thetaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner. Oncogene (2003) 0.89

Initial success with gubernacular-sparing laparoscopic-assisted Fowler-Stephens orchidopexy for intra-abdominal testes. J Laparoendosc Adv Surg Tech A (2011) 0.89

Dual-porosity hollow nanoparticles for the immunoprotection and delivery of nonhuman enzymes. Nano Lett (2014) 0.87

The polyketide MPBD initiates the SDF-1 signaling cascade that coordinates terminal differentiation in Dictyostelium. Eukaryot Cell (2011) 0.87

Importance of Toll-like receptor 9 in host defense against M1T1 group A Streptococcus infections. J Innate Immun (2011) 0.86

Synthesis and characterization of PEGylated toll like receptor 7 ligands. Bioconjug Chem (2011) 0.86

Measurements of isoprene-derived organosulfates in ambient aerosols by aerosol time-of-flight mass spectrometry-part 2: temporal variability and formation mechanisms. Environ Sci Technol (2011) 0.86

CpG oligonucleotides partially inhibit growth of Mycobacterium tuberculosis, but not Salmonella or Listeria, in human monocyte-derived macrophages. FEMS Immunol Med Microbiol (2005) 0.85

Measurements of isoprene-derived organosulfates in ambient aerosols by aerosol time-of-flight mass spectrometry - part 1: single particle atmospheric observations in Atlanta. Environ Sci Technol (2011) 0.85

Fluorescent microscope system to monitor real-time interactions between focused ultrasound, echogenic drug delivery vehicles, and live cell membranes. Ultrasonics (2012) 0.84

TLR4-dependent activation of dendritic cells by an HMGB1-derived peptide adjuvant. J Transl Med (2014) 0.84

Functional relationships between Rad18 and WRNIP1 in vertebrate cells. Biol Pharm Bull (2006) 0.84

Localized in vivo activation of a photoactivatable doxorubicin prodrug in deep tumor tissue. Photochem Photobiol (2013) 0.84

Liposomal immunostimulatory DNA sequence (ISS-ODN): an efficient parenteral and mucosal adjuvant for influenza and hepatitis B vaccines. Vaccine (2002) 0.84

Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1. J Immunol (2012) 0.84

Enhancing magnetic resonance imaging tumor detection with fluorescence intensity and lifetime imaging. J Biomed Opt (2011) 0.84

Directed hybridization of DNA derivatized nanoparticles into higher order structures. Nano Lett (2008) 0.83

Discovery and early clinical evaluation of BMS-605339, a potent and orally efficacious tripeptidic acylsulfonamide NS3 protease inhibitor for the treatment of hepatitis C virus infection. J Med Chem (2014) 0.83

Analysis of high-throughput screening assays using cluster enrichment. Stat Med (2012) 0.83

Enrichment of Yersinia pestis from blood cultures enables rapid antimicrobial susceptibility determination by flow cytometry. Adv Exp Med Biol (2007) 0.83

The search for early markers of plague: evidence for accumulation of soluble Yersinia pestis LcrV in bubonic and pneumonic mouse models of disease. FEMS Immunol Med Microbiol (2010) 0.82

Tamm-Horsfall protein-associated nucleotides in patients with interstitial cystitis. BJU Int (2013) 0.82

High-efficiency liposomal encapsulation of a tyrosine kinase inhibitor leads to improved in vivo toxicity and tumor response profile. Int J Nanomedicine (2013) 0.81

Performance trade-offs in single-photon avalanche diode miniaturization. Rev Sci Instrum (2007) 0.81

In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model. Cell Immunol (2008) 0.80

Synthesis and characterization of lipid-polymer hybrid nanoparticles with pH-triggered poly(ethylene glycol) shedding. Langmuir (2011) 0.80

Electric-field-directed assembly of biomolecular-derivatized nanoparticles into higher-order structures. Small (2007) 0.80

Early sensing of Yersinia pestis airway infection by bone marrow cells. Front Cell Infect Microbiol (2012) 0.80

A novel homogeneous immunoassay for anthrax detection based on the AlphaLISA method: detection of B. anthracis spores and protective antigen (PA) in complex samples. Anal Bioanal Chem (2013) 0.80

DeNAno: Selectable deoxyribonucleic acid nanoparticle libraries. J Biotechnol (2009) 0.79

A traditional Japanese medicine mitigates TNBS-induced colitis in rats. Scand J Gastroenterol (2006) 0.79

Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand. J Innate Immun (2013) 0.79

The Role of Plasmacytoid and Myeloid Dendritic Cells in Induction of Asthma in a Mouse Model and the Effect of a TLR9 Agonist on Dendritic Cells. Allergy Asthma Immunol Res (2011) 0.79

Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers. Food Funct (2015) 0.78

Performance characteristics of updated INNO-LiPA assays for molecular typing of human leukocyte antigen A (HLA-A), HLA-B, and HLA-DQB1 alleles. Clin Diagn Lab Immunol (2004) 0.78

Self-medication with gamma-hydroxybutyrate to reduce alcohol intake. South Med J (2002) 0.78

Assembly and targeting of liposomal nanoparticles encapsulating quantum dots. Bioconjug Chem (2011) 0.78

Concentration of Bacillus spores by using silica magnetic particles. Anal Chem (2006) 0.78

Frequency and predictors of tablet splitting in statin prescriptions: a population-based analysis. Open Med (2008) 0.78

Coupled rolling circle amplification loop-mediated amplification for rapid detection of short DNA sequences. Biotechniques (2008) 0.77

Role of urinary cations in the aetiology of bladder symptoms and interstitial cystitis. BJU Int (2014) 0.77

Prolonged QTc interval due to escitalopram overdose. J Miss State Med Assoc (2010) 0.77

Increased aldehyde dehydrogenase activity in high-risk chronic lymphocytic leukemia. Leuk Lymphoma (2012) 0.77

Rapid homogenous time-resolved fluorescence (HTRF) immunoassay for anthrax detection. J Fluoresc (2014) 0.77

Inhibition of keratinocyte proliferation by phospholipid-conjugates of a TLR7 ligand in a Myc-induced hyperplastic actinic keratosis model in the absence of systemic side effects. Eur J Dermatol (2013) 0.77

Clinician vs mathematical statistical models: which is better at predicting an abnormal chest radiograph finding in injured patients? Am J Emerg Med (2007) 0.77

Chronic orofacial pain in dental patients: retrospective investigation over 12 years. Acta Med Okayama (2014) 0.77

Use of UV powder for surveillance to improve environmental cleaning. Infect Control Hosp Epidemiol (2011) 0.76

Regarding: "Pediatrics varicocele surgery: 10 years of experience in two pediatric surgical centers". J Laparoendosc Adv Surg Tech A (2012) 0.75

Synthesis of 5-(6-hydroxy-7H-purine-8-ylthio)- 2-(N-hydroxyformamido)pentanoic acid. Beilstein J Org Chem (2010) 0.75

Systematic inclusion of mandatory interprofessional education in health professions curricula at Gunma University: a report of student self-assessment in a nine-year implementation. Hum Resour Health (2009) 0.75

Allergic reactions to local anesthetics in dental patients: analysis of intracutaneous and challenge tests. Open Dent J (2011) 0.75

An innovative system for 3D clinical photography in the resource-limited settings. J Transl Med (2014) 0.75

Phase I adjuvant radiation with docetaxel in high-risk head and neck cancer. Am J Clin Oncol (2009) 0.75

Risk factors affecting third molar autotransplantation during 5 and 10 years. Bull Tokyo Dent Coll (2014) 0.75

Procedures for treating spaces vacated by loss of transplanted teeth. Bull Tokyo Dent Coll (2013) 0.75

[Hyperlactemia during undiagnosed pheochromocytoma resection under laparoscopy]. Masui (2012) 0.75

"A window on tissue" - Using facial orientation to control endoscopic views of tissue depth. Conf Proc IEEE Eng Med Biol Soc (2010) 0.75

Development and characterization of an aircraft aerosol time-of-flight mass spectrometer. Anal Chem (2009) 0.75

A.S.P.E.N. parenteral nutrition safety consensus recommendations: translation into practice. Nutr Clin Pract (2014) 0.75

Survival rate in autotransplanted premolars with complete root formation: a retrospective clinical survey. Bull Tokyo Dent Coll (2013) 0.75