Possible role of S-equol on bone loss via amelioration of inflammatory indices in ovariectomized mice.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 3705151)

Published in J Clin Biochem Nutr on June 01, 2013

Authors

Yoriko Nishide1, Miki Tadaishi, Masuko Kobori, Yuko Tousen, Michiko Kato, Masaki Inada, Chisato Miyaura, Yoshiko Ishimi

Author Affiliations

1: Department of Food Function and Labeling, National Institute of Health and Nutrition, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8636, Japan ; Cooperative Major in Advanced Health Science, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei, Tokyo 184-8588, Japan.

Articles cited by this

Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest (2003) 41.22

AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr (1993) 16.37

PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J Clin Invest (2004) 5.29

Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha. J Clin Invest (2000) 3.15

Cloning of a lymphoid-specific cDNA encoding a protein binding the regulatory octamer DNA motif. Science (1988) 3.01

Playing with bone and fat. J Cell Biochem (2006) 2.94

Adipocyte differentiation and gene expression. J Nutr (2000) 2.79

Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Natl Acad Sci U S A (2001) 2.56

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation. Blood (2004) 2.33

B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood (2007) 2.16

The role of the immune system in the pathophysiology of osteoporosis. Immunol Rev (2005) 2.03

Phyto-oestrogens and cancer. Lancet Oncol (2002) 1.91

Interaction of phytoestrogens with estrogen receptors alpha and beta. Biol Pharm Bull (2001) 1.90

The role of CD40 ligand in costimulation and T-cell activation. Immunol Rev (1996) 1.78

A brief historical overview of the past two decades of soy and isoflavone research. J Nutr (2010) 1.75

Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines. Blood (2000) 1.74

S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr (2005) 1.73

Cloning and expression of mouse fatty acid synthase and other specific mRNAs. Developmental and hormonal regulation in 3T3-L1 cells. J Biol Chem (1988) 1.52

Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: similarity to estrogen deficiency. Proc Natl Acad Sci U S A (1997) 1.51

Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow. J Clin Invest (1994) 1.51

Exposure of KS483 cells to estrogen enhances osteogenesis and inhibits adipogenesis. J Bone Miner Res (2002) 1.49

Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency. J Clin Invest (2002) 1.47

Obesity, inflammation and the immune system. Proc Nutr Soc (2012) 1.47

Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta. Endocrinology (2002) 1.40

IL-7: a key regulator of B lymphopoiesis. Semin Immunol (2005) 1.32

IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis. Semin Immunol (2012) 1.27

Equol: pharmacokinetics and biological actions. J Nutr (2010) 1.25

Selective effects of genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency. Endocrinology (1999) 1.09

Role of T cells in ovariectomy induced bone loss--revisited. J Bone Miner Res (2012) 1.09

Genetic and environmental influences on bone mineral density in pre- and post-menopausal women. Osteoporos Int (2005) 1.07

The pharmacokinetic behavior of the soy isoflavone metabolite S-(-)equol and its diastereoisomer R-(+)equol in healthy adults determined by using stable-isotope-labeled tracers. Am J Clin Nutr (2009) 1.07

Osteoclasts and the immune system. J Bone Miner Metab (2009) 1.02

Early B-lymphocyte precursors and their regulation by sex steroids. Immunol Rev (2000) 1.01

Estrogens, bone loss and preservation. Osteoporos Int (1990) 1.01

RANKL-independent human osteoclast formation with APRIL, BAFF, NGF, IGF I and IGF II. Bone (2010) 0.99

Daidzein prevents the increase in CD4+CD28null T cells and B lymphopoesis in ovariectomized mice: a key mechanism for anti-osteoclastogenic effect. PLoS One (2011) 0.98

Effect of estrogens on bone marrow adipogenesis and Sirt1 in aging C57BL/6J mice. Biogerontology (2009) 0.98

Equol, a metabolite of daidzein, inhibits bone loss in ovariectomized mice. J Nutr (2004) 0.97

Understanding the mechanisms of senile osteoporosis: new facts for a major geriatric syndrome. J Am Geriatr Soc (2008) 0.96

How B cells influence bone biology in health and disease. Bone (2010) 0.94

Natural S-equol decreases bone resorption in postmenopausal, non-equol-producing Japanese women: a pilot randomized, placebo-controlled trial. Menopause (2011) 0.90

Premature T cell senescence in Ovx mice is inhibited by repletion of estrogen and medicarpin: a possible mechanism for alleviating bone loss. Osteoporos Int (2011) 0.89

Does the effect of soy phytoestrogens on bone in postmenopausal women depend on the equol-producing phenotype? Nutr Rev (2007) 0.85

Ovariectomy-induced bone loss and the hematopoietic system. Bone Miner (1993) 0.84

Nutrition as prevention and treatment of osteoporosis. Physiol Res (2009) 0.83

Toxicokinetics and lack of uterotropic effect of orally administered S-equol. Food Chem Toxicol (2012) 0.81

Genotoxicity assessment of S-equol in bacterial mutation, chromosomal aberration, and rodent bone marrow micronucleus tests. Food Chem Toxicol (2010) 0.79

Dietary equol and bone metabolism in postmenopausal Japanese women and osteoporotic mice. J Nutr (2010) 0.79

S-equol and the fermented soy product SE5-OH containing S-equol similarly decrease ovariectomy-induced increase in rat tail skin temperature in an animal model of hot flushes. Menopause (2011) 0.77

Comparative activities of the S-enantiomer and racemic forms of equol on bone fragility in ovariectomized mice. Biosci Biotechnol Biochem (2012) 0.77

Articles by these authors

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol (2009) 6.62

A ubiquitin ligase complex assembles linear polyubiquitin chains. EMBO J (2006) 4.95

Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. J Cell Biol (2004) 4.16

Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification. Proc Natl Acad Sci U S A (2004) 3.27

Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques. Circulation (2005) 2.01

Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8). FASEB J (2007) 1.74

Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2. Mol Cell (2005) 1.59

Estrogen and androgen play distinct roles in bone turnover in male mice before and after reaching sexual maturity. Bone (2005) 1.58

A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism. J Biol Chem (2006) 1.52

Effects of soy isoflavone extract supplements on blood pressure in adult humans: systematic review and meta-analysis of randomized placebo-controlled trials. J Hypertens (2010) 1.50

Matrix metalloproteinases and bone. Bone (2008) 1.39

An essential role of cytosolic phospholipase A2alpha in prostaglandin E2-mediated bone resorption associated with inflammation. J Exp Med (2003) 1.29

Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice. J Nutr (2003) 1.19

Membrane-bound prostaglandin E synthase-1-mediated prostaglandin E2 production by osteoblast plays a critical role in lipopolysaccharide-induced bone loss associated with inflammation. J Immunol (2006) 1.15

Effects of isoflavone and exercise on BMD and fat mass in postmenopausal Japanese women: a 1-year randomized placebo-controlled trial. J Bone Miner Res (2006) 1.14

Induction of apoptosis in cancer cells by Bilberry (Vaccinium myrtillus) and the anthocyanins. J Agric Food Chem (2003) 1.13

A combination of dietary fructooligosaccharides and isoflavone conjugates increases femoral bone mineral density and equol production in ovariectomized mice. J Nutr (2002) 1.09

MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD(MO). J Clin Invest (2005) 1.07

Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women: a randomized placebo-controlled trial. Metabolism (2006) 1.05

Assimilation of endogenous nicotinamide riboside is essential for calorie restriction-mediated life span extension in Saccharomyces cerevisiae. J Biol Chem (2009) 1.04

Possible role of equol status in the effects of isoflavone on bone and fat mass in postmenopausal Japanese women: a double-blind, randomized, controlled trial. Menopause (2007) 1.03

Combined intervention of soy isoflavone and moderate exercise prevents body fat elevation and bone loss in ovariectomized mice. Metabolism (2004) 1.01

Antiproliferative effect on human cancer cell lines after treatment with nimbolide extracted from an edible part of the neem tree (Azadirachta indica). Phytother Res (2007) 1.01

MMP-13 regulates growth of wound granulation tissue and modulates gene expression signatures involved in inflammation, proteolysis, and cell viability. PLoS One (2012) 1.00

Ovariectomy in mice decreases lipid metabolism-related gene expression in adipose tissue and skeletal muscle with increased body fat. J Nutr Sci Vitaminol (Tokyo) (2005) 0.99

Effect of soy isoflavone extract supplements on bone mineral density in menopausal women: meta-analysis of randomized controlled trials. Asia Pac J Clin Nutr (2010) 0.98

Assessment of effectiveness of oral administration of collagen peptide on bone metabolism in growing and mature rats. J Bone Miner Metab (2004) 0.98

Increased monoamine concentration in the brain and blood of fetal thalidomide- and valproic acid-exposed rat: putative animal models for autism. Pediatr Res (2002) 0.98

Equol, a metabolite of daidzein, inhibits bone loss in ovariectomized mice. J Nutr (2004) 0.97

Dietary hesperidin exerts hypoglycemic and hypolipidemic effects in streptozotocin-induced marginal type 1 diabetic rats. J Clin Biochem Nutr (2009) 0.96

Caffeine lengthens circadian rhythms in mice. Biochem Biophys Res Commun (2011) 0.94

Quantitation of NAD+ biosynthesis from the salvage pathway in Saccharomyces cerevisiae. Yeast (2009) 0.93

High bone mass gained by exercise in growing male mice is increased by subsequent reduced exercise. J Appl Physiol (1985) (2004) 0.93

Feeding cues and injected nutrients induce acute expression of multiple clock genes in the mouse liver. PLoS One (2011) 0.92

Main-chain dominated amyloid structures demonstrated by the effect of high pressure. J Mol Biol (2005) 0.91

The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination. J Biol Chem (2008) 0.91

Very small mobile repeated elements in cyanobacterial genomes. Genome Res (2008) 0.91

Toll-like receptor 2 heterodimers, TLR2/6 and TLR2/1 induce prostaglandin E production by osteoblasts, osteoclast formation and inflammatory periodontitis. Biochem Biophys Res Commun (2012) 0.91

Effects of soy isoflavone supplements on bone turnover markers in menopausal women: systematic review and meta-analysis of randomized controlled trials. Bone (2010) 0.90

Ergosterol peroxide, an apoptosis-inducing component isolated from Sarcodon aspratus (Berk.) S. Ito. Biosci Biotechnol Biochem (2005) 0.90

Natural S-equol decreases bone resorption in postmenopausal, non-equol-producing Japanese women: a pilot randomized, placebo-controlled trial. Menopause (2011) 0.90

[Animal models for bone and joint disease. Ovariectomized and orchidectomized animals]. Clin Calcium (2011) 0.89

Differential effects of isoflavones on bone formation in growing male and female mice. Metabolism (2007) 0.89

Apoptosis, necrosis and cell proliferation-inhibition by cyclosporine A in U937 cells (a human monocytic cell line). Pharmacol Res (2006) 0.88

Construction of a novel synergistic system for production and recovery of secreted recombinant proteins by the cell surface engineering. Appl Microbiol Biotechnol (2007) 0.88

Identification of potential calorie restriction-mimicking yeast mutants with increased mitochondrial respiratory chain and nitric oxide levels. J Aging Res (2011) 0.87

Resistant starch promotes equol production and inhibits tibial bone loss in ovariectomized mice treated with daidzein. Metabolism (2011) 0.86

Pyrroloquinoline quinone inhibits the fibrillation of amyloid proteins. Prion (2010) 0.86

Comparative activities of daidzein metabolites, equol and O-desmethylangolensin, on bone mineral density and lipid metabolism in ovariectomized mice and in osteoclast cell cultures. Eur J Nutr (2008) 0.86

Prevention of aortic calcification by etidronate in the renal failure rat model. Eur J Pharmacol (2006) 0.85

Role of prostaglandin E produced by osteoblasts in osteolysis due to bone metastasis. Biochem Biophys Res Commun (2003) 0.85

Dietary phloridzin reduces blood glucose levels and reverses Sglt1 expression in the small intestine in streptozotocin-induced diabetic mice. J Agric Food Chem (2009) 0.85

Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women. J Bone Miner Metab (2013) 0.85

Puerariae radix prevents bone loss in ovariectomized mice. J Bone Miner Metab (2003) 0.84

Autophagy impairment stimulates PS1 expression and gamma-secretase activity. Autophagy (2010) 0.84

AICAR response element binding protein (AREBP), a key modulator of hepatic glucose production regulated by AMPK in vivo. Biochem Biophys Res Commun (2011) 0.84

A novel carborane analog, BE360, with a carbon-containing polyhedral boron-cluster is a new selective estrogen receptor modulator for bone. Biochem Biophys Res Commun (2009) 0.83

Procyanidin trimers to pentamers fractionated from apple inhibit melanogenesis in B16 mouse melanoma cells. J Agric Food Chem (2005) 0.83

Effects of geranylgeranoic acid in bone: induction of osteoblast differentiation and inhibition of osteoclast formation. J Bone Miner Res (2002) 0.83

Combined intervention of exercise and genistein prevented androgen deficiency-induced bone loss in mice. J Appl Physiol (1985) (2003) 0.83

Hesperidin prevents androgen deficiency-induced bone loss in male mice. Phytother Res (2013) 0.83

High-salt diet advances molecular circadian rhythms in mouse peripheral tissues. Biochem Biophys Res Commun (2010) 0.83

Acyclo-retinoic acid induces apoptosis in human prostate cancer cells. Anticancer Res (2002) 0.83

Intrusion of molars with implants as anchorage: a report of two cases. Clin Implant Dent Relat Res (2006) 0.83

Resveratrol regulates circadian clock genes in Rat-1 fibroblast cells. Biosci Biotechnol Biochem (2008) 0.83

Associations between the Serum 25(OH)D Concentration and Lipid Profiles in Japanese Men. J Atheroscler Thromb (2014) 0.83

Polymethoxy flavonoids, nobiletin and tangeretin, prevent lipopolysaccharide-induced inflammatory bone loss in an experimental model for periodontitis. J Pharmacol Sci (2012) 0.83

Estimated average daily intake of antioxidants from typical vegetables consumed in Japan: a preliminary study. Biosci Biotechnol Biochem (2010) 0.83

Nobiletin, a polymethoxy flavonoid, suppresses bone resorption by inhibiting NFκB-dependent prostaglandin E synthesis in osteoblasts and prevents bone loss due to estrogen deficiency. J Pharmacol Sci (2011) 0.82

Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm. Am J Physiol Endocrinol Metab (2013) 0.82

[Cytokines in bone diseases. Cytokine and postmenopausal osteoporosis]. Clin Calcium (2010) 0.82

Hypoglycemic and hypolipidemic effects of hesperidin and cyclodextrin-clathrated hesperetin in Goto-Kakizaki rats with type 2 diabetes. Biosci Biotechnol Biochem (2009) 0.82

Systems for the detection and analysis of protein-protein interactions. Appl Microbiol Biotechnol (2006) 0.81

Dietary bisphenol A prevents ovarian degeneration and bone loss in female mice lacking the aromatase gene (Cyp19 ). Eur J Biochem (2002) 0.81

The correlation between postmenopausal osteoporosis and inflammatory periodontitis regarding bone loss in experimental models. Exp Anim (2012) 0.81

Hyaluronan inhibits bone resorption by suppressing prostaglandin E synthesis in osteoblasts treated with interleukin-1. Biochem Biophys Res Commun (2009) 0.80

Bi-phasic effect of equol on adipocyte differentiation of MC3T3-L1 cells. Biosci Biotechnol Biochem (2013) 0.80

Endoplasmic reticulum stress enhances γ-secretase activity. Biochem Biophys Res Commun (2011) 0.80

Prevention and reversal of lipotoxicity-induced hepatic insulin resistance and steatohepatitis in mice by an antioxidant carotenoid, β-cryptoxanthin. Endocrinology (2015) 0.80

Novel vitamin D3 analogs, 1alpha, 25(OH)2D(3)-26, 23-lactam (DLAMs), antagonize bone resorption via suppressing RANKL expression in osteoblasts. Biochem Biophys Res Commun (2008) 0.80

Capsaicin, a TRPV1 Ligand, Suppresses Bone Resorption by Inhibiting the Prostaglandin E Production of Osteoblasts, and Attenuates the Inflammatory Bone Loss Induced by Lipopolysaccharide. ISRN Pharmacol (2012) 0.80

Combined effects of soy isoflavone and fish oil on ovariectomy-induced bone loss in mice. J Bone Miner Metab (2010) 0.80

Inhibition of colon cancer (HT-29) cell proliferation by a triterpenoid isolated from Azadirachta indica is accompanied by cell cycle arrest and up-regulation of p21. Planta Med (2006) 0.80

Late-onset increases in oxidative stress and other tumorigenic activities and tumors with a Ha-ras mutation in the liver of adult male C3H mice gestationally exposed to arsenic. Toxicol Sci (2012) 0.79

Effects of extracted soy isoflavones alone on blood total and LDL cholesterol: Meta-analysis of randomized controlled trials. Ther Clin Risk Manag (2008) 0.79

Reassessment of antioxidant activity of arbutin: multifaceted evaluation using five antioxidant assay systems. Free Radic Res (2010) 0.79

Identification of glucose transporter 4 knockdown-dependent transcriptional activation element on the retinol binding protein 4 gene promoter and requirement of the 20 S proteasome subunit for transcriptional activity. J Biol Chem (2010) 0.79