Published in Science on July 29, 1988
A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor. EMBO J (1989) 4.47
The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein. EMBO J (1989) 3.42
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol Cell Biol (1992) 3.10
Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene. EMBO J (1991) 3.00
A helix-loop-helix protein related to the immunoglobulin E box-binding proteins. Mol Cell Biol (1990) 2.90
Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription. J Exp Med (1991) 2.88
High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors. EMBO J (1995) 2.48
Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. Mol Cell Biol (1992) 2.47
LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes. Mol Cell Biol (1991) 2.41
NF-kappa B protein purification from bovine spleen: nucleotide stimulation and binding site specificity. Proc Natl Acad Sci U S A (1988) 2.39
Eukaryotic transcription factors. Biochem J (1990) 2.16
Activation of the erythropoietin receptor promoter by transcription factor GATA-1. Proc Natl Acad Sci U S A (1991) 2.10
Cross-binding of factors to functionally different promoter elements in c-fos and skeletal actin genes. Mol Cell Biol (1989) 1.94
A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers. Mol Cell Biol (1991) 1.89
Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter. EMBO J (1989) 1.70
Human chromosome 12 is required for optimal interactions between Tat and TAR of human immunodeficiency virus type 1 in rodent cells. J Virol (1992) 1.69
Multiple Oct2 isoforms are generated by alternative splicing. Nucleic Acids Res (1991) 1.65
A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation. EMBO J (1991) 1.65
An autoregulatory enhancer element of the Drosophila homeotic gene Deformed. EMBO J (1990) 1.52
Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors. Mol Cell Biol (1990) 1.52
Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes. Nucleic Acids Res (1991) 1.51
The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2. Mol Cell Biol (1990) 1.49
A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells. Nucleic Acids Res (1992) 1.41
Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activity. Mol Cell Biol (1992) 1.35
Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins. Nucleic Acids Res (1990) 1.32
The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements. Proc Natl Acad Sci U S A (1991) 1.32
Complex regulation of the immunoglobulin mu heavy-chain gene enhancer: microB, a new determinant of enhancer function. Mol Cell Biol (1990) 1.31
Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element. Mol Cell Biol (1992) 1.27
Identification and purification of a protein that binds DNA cooperatively with the yeast SWI5 protein. Mol Cell Biol (1993) 1.26
Purification of early-B-cell factor and characterization of its DNA-binding specificity. Mol Cell Biol (1993) 1.24
Silencing of the expression of the immunoglobulin kappa gene in non-B cells. Mol Cell Biol (1991) 1.24
Staf, a novel zinc finger protein that activates the RNA polymerase III promoter of the selenocysteine tRNA gene. EMBO J (1995) 1.20
Involvement of a second lymphoid-specific enhancer element in the regulation of immunoglobulin heavy-chain gene expression. Mol Cell Biol (1990) 1.19
Immunoglobulin enhancer and promoter motifs 5' of the B29 B-cell-specific gene. Proc Natl Acad Sci U S A (1989) 1.19
DNA binding properties of YB-1 and dbpA: binding to double-stranded, single-stranded, and abasic site containing DNAs. Nucleic Acids Res (1991) 1.19
Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences. Mol Cell Biol (1991) 1.17
The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes. Mol Cell Biol (1990) 1.13
Gene structure and characterization of the murine homologue of the B cell-specific transcriptional coactivator OBF-1. Nucleic Acids Res (1996) 1.13
The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP. Nucleic Acids Res (1994) 1.13
NF-IL6-mediated transcriptional activation of the long terminal repeat of the human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1993) 1.11
Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation. EMBO J (1993) 1.07
Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation. Mol Cell Biol (1991) 1.07
Identification of a mammalian nuclear factor and human cDNA-encoded proteins that recognize DNA containing apurinic sites. Proc Natl Acad Sci U S A (1990) 1.05
Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer. Mol Cell Biol (1989) 1.05
Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors have been highly conserved during vertebrate evolution. Proc Natl Acad Sci U S A (1990) 1.03
B cell development and immunoglobulin transcription in Oct-1-deficient mice. Proc Natl Acad Sci U S A (2004) 1.03
Conserved enhancer and silencer elements responsible for differential Adh transcription in Drosophila cell lines. Mol Cell Biol (1990) 1.02
The B-cell and neuronal forms of the octamer-binding protein Oct-2 differ in DNA-binding specificity and functional activity. Mol Cell Biol (1991) 1.02
A distinct octamer-binding protein present in malignant melanoma cells. Nucleic Acids Res (1988) 1.00
B29 gene products complex with immunoglobulins on B lymphocytes. Proc Natl Acad Sci U S A (1992) 0.98
Using altered specificity Oct-1 and Oct-2 mutants to analyze the regulation of immunoglobulin gene transcription. EMBO J (1997) 0.98
Cloning, chromosomal localization and expression pattern of the POU domain gene Oct-11. Nucleic Acids Res (1993) 0.97
CRISP-3, a protein with homology to plant defense proteins, is expressed in mouse B cells under the control of Oct2. Mol Cell Biol (1996) 0.93
Transformation by homeobox genes can be mediated by selective transcriptional repression. EMBO J (1994) 0.93
Induction of the POU domain transcription factor Oct-2 during T-cell activation by cognate antigen. Mol Cell Biol (1992) 0.93
Octamer-binding proteins in diverse hemopoietic cells. Mol Cell Biol (1990) 0.92
Oct-1 [corrected] and Oct-2 DNA-binding site specificity is regulated in vitro by different kinases. Biochem J (1996) 0.91
Chicken beta B1-crystallin gene expression: presence of conserved functional polyomavirus enhancer-like and octamer binding-like promoter elements found in non-lens genes. Mol Cell Biol (1991) 0.91
Activity and interleukin 1 responsiveness of SV40 enhancer motifs in a rodent immature T cell line. EMBO J (1990) 0.91
Oct transcription factors in development and stem cells: insights and mechanisms. Development (2013) 0.91
Both muscle-specific and ubiquitous nuclear factors are required for muscle-specific expression of the myosin heavy-chain beta gene in cultured cells. Mol Cell Biol (1992) 0.90
Identification of a novel factor that interacts with an immunoglobulin heavy-chain promoter and stimulates transcription in conjunction with the lymphoid cell-specific factor OTF2. Mol Cell Biol (1990) 0.90
The B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1. PLoS Pathog (2012) 0.89
Functional differences between the Oct2 transactivation domains determine the transactivation potential of individual Oct2 isoforms. Nucleic Acids Res (1994) 0.89
dOct2, a Drosophila Oct transcription factor that functions in yeast. Proc Natl Acad Sci U S A (1992) 0.89
Differential expression of four members of the POU family of proteins in activated and phorbol 12-myristate 13-acetate-treated Jurkat T cells. Proc Natl Acad Sci U S A (1993) 0.86
Transcription factor binding sites in the pol gene intragenic regulatory region of HIV-1 are important for virus infectivity. Nucleic Acids Res (2005) 0.86
Functional analysis of defined mutations in the immunoglobulin heavy-chain enhancer in transgenic mice. Nucleic Acids Res (1992) 0.86
A conserved sequence block in murine and human T cell receptor (TCR) Jalpha region is a composite element that enhances TCR alpha enhancer activity and binds multiple nuclear factors. Proc Natl Acad Sci U S A (1998) 0.85
Regulation of JC virus expression in B lymphocytes. J Virol (1994) 0.85
Diphosphoryl lipid A from Rhodobacter sphaeroides transiently activates NF-kappa B but inhibits lipopolysaccharide induction of kappa light chain and Oct-2 in the B-cell lymphoma line 70Z/3. Infect Immun (1995) 0.84
A gamma interferon-unresponsive variant of cell line 70Z/3, IFN-4, can be partially rescued by phorbol myristate acetate. Mol Cell Biol (1989) 0.82
Oct2 and Obf1 as Facilitators of B:T Cell Collaboration during a Humoral Immune Response. Front Immunol (2014) 0.81
Redundant role of tissue-selective TAF(II)105 in B lymphocytes. Mol Cell Biol (2002) 0.80
Possible role of S-equol on bone loss via amelioration of inflammatory indices in ovariectomized mice. J Clin Biochem Nutr (2013) 0.80
Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2. Proc Natl Acad Sci U S A (2016) 0.79
Characterization of enhancer elements and their mutations in the long terminal repeat of feline endogenous RD-114 proviruses. J Virol (1989) 0.79
Mouse lymphoid cell line selected to have high immunoglobulin promoter activity. Mol Cell Biol (2002) 0.78
Lymphoid-specific transcriptional activation by components of the IgH enhancer: studies on the E2/E3 and octanucleotide elements. Nucleic Acids Res (1990) 0.77
Interaction of a nuclear protein with a palindromic sequence of the mouse immunoglobulin lambda 2-chain gene promoter is important for its transcription. Mol Cell Biol (1990) 0.77
Xenopus laevis Oct-1 does not bind to certain histone H2B gene promoter octamer motifs for which a novel octamer-binding factor has high affinity. Nucleic Acids Res (1991) 0.77
A novel role for Oct-2 in the lipopolysaccharide-mediated induction of resistin gene expression in RAW264.7 cells. Biochem J (2007) 0.76
Extinction of T cell receptor alpha-chain gene expression accompanied by loss of the lymphoid enhancer-binding factor 1 (LEF-1) in murine somatic cell hybrids. Mol Cell Biol (1993) 0.76
Functional characterization of the cis-regulatory elements of the rat ribophorin I gene. Nucleic Acids Res (1995) 0.75
Long-Range Modulation of PAG1 Expression by 8q21 Allergy Risk Variants. Am J Hum Genet (2015) 0.75
Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles. Nucleic Acids Res (1998) 0.75
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Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell (1983) 25.46
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci U S A (1993) 22.33
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell (1989) 21.54
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell (1986) 20.08
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An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature (1987) 19.23
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Five intermediate complexes in transcription initiation by RNA polymerase II. Cell (1989) 9.22
A detailed model of reverse transcription and tests of crucial aspects. Cell (1979) 8.93
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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses. Cell (1995) 7.55
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