Genomic instability in liver cells caused by an LPS-induced bystander-like effect.

PubWeight™: 0.76‹?›

🔗 View Article (PMC 3706549)

Published in PLoS One on July 09, 2013

Authors

Igor Kovalchuk1, Paul Walz, James Thomas, Olga Kovalchuk

Author Affiliations

1: Department of Biological Sciences, University of Lethbridge, Lethbridge, Canada. igor.kovalchuk@uleth.ca

Articles cited by this

Global cancer statistics, 2002. CA Cancer J Clin (2005) 119.22

Helicobacter pylori infection. N Engl J Med (2002) 14.81

NF-kappa B: ten years after. Cell (1996) 12.80

MeCP2, a key contributor to neurological disease, activates and represses transcription. Science (2008) 10.11

ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J Biol Chem (2001) 8.78

Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains. J Bacteriol (1983) 8.19

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature (2005) 7.45

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development. Curr Opin Cell Biol (1998) 6.28

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Genes Dev (2003) 3.74

Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock. J Exp Med (2005) 2.83

Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B. J Biol Chem (2001) 2.50

Hippocampal sclerosis can be reliably detected by magnetic resonance imaging. Neurology (1990) 1.98

Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages. J Biol Chem (2000) 1.57

Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo. Oncogene (2006) 1.47

Heat-killed bacteria induce genome instability in mouse small intestine, liver and spleen tissues. Cell Cycle (2009) 1.43

Determination of total protein content of bacterial cells by SYPRO staining and flow cytometry. Appl Environ Microbiol (1999) 1.40

Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells. PLoS One (2010) 1.37

The role of the liver in the response to LPS: experimental and clinical findings. J Endotoxin Res (2002) 1.37

Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. J Biol Chem (2002) 1.35

Enhanced H2AX phosphorylation, DNA replication fork arrest, and cell death in the absence of Chk1. Mol Biol Cell (2010) 1.34

Dual-specificity phosphatase 1: a critical regulator of innate immune responses. Biochem Soc Trans (2006) 1.30

Human endothelial-cell specific molecule-1 binds directly to the integrin CD11a/CD18 (LFA-1) and blocks binding to intercellular adhesion molecule-1. J Immunol (2001) 1.25

Neutralizing antibodies to Escherichia coli Vero cytotoxin 1 and antibodies to O157 lipopolysaccharide in healthy farm family members and urban residents. J Clin Microbiol (1996) 1.18

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells. Mol Biol Cell (2012) 1.12

Chronic Chlamydophila pneumoniae infection in lung cancer, a risk factor: a case-control study. J Med Microbiol (2003) 1.06

Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells. Lab Invest (2001) 1.04

Epigenetic and transcriptional changes which follow Epstein-Barr virus infection of germinal center B cells and their relevance to the pathogenesis of Hodgkin's lymphoma. J Virol (2011) 1.04

MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta. J Biol Chem (2007) 1.03

Proliferating cell nuclear antigen (PCNA) may function as a double homotrimer complex in the mammalian cell. J Biol Chem (2005) 1.03

Epigenetic dysregulation underlies radiation-induced transgenerational genome instability in vivo. Int J Radiat Oncol Biol Phys (2006) 1.03

Use of in-stream reservoirs to reduce bacterial contamination of rural watersheds. Sci Total Environ (2005) 0.97

Profiles of circulating inflammatory- and anti-inflammatory cytokines in patients with hemolytic uremic syndrome due to E. coli O157 infection. Cytokine (1998) 0.97

Interleukin-6 expression was regulated by epigenetic mechanisms in response to influenza virus infection or dsRNA treatment. Mol Immunol (2011) 0.96

Outbred mice with long-term Helicobacter felis infection develop both gastric lymphoid tissue and glandular hyperplastic lesions. J Pathol (2000) 0.96

Marked enhancement of rat urinary bladder carcinogenesis by heat-killed Escherichia coli. Cancer Res (1992) 0.92

DNA Methylation Fluctuation Induced by Virus Infection Differs between MD-resistant and -susceptible Chickens. Front Genet (2012) 0.88

Intestinal trefoil factor/TFF3 promotes re-epithelialization of corneal wounds. J Biol Chem (2008) 0.87

Increased and correlated nuclear factor-kappa B and Ku autoantigen activities are associated with development of multidrug resistance. Oncogene (2001) 0.87

Infrequent COX-2 expression due to promoter hypermethylation in gastric cancers in Dalian, China. Hum Pathol (2006) 0.83

Ulcerative colitis. Colorectal cancer risk in an unselected population. Ann Surg (1988) 0.82

Helicobacter pylori infection promotes methylation of WWOX gene in human gastric cancer. Biochem Biophys Res Commun (2011) 0.81

Lipopolysaccharide renders transgenic mice expressing human serum amyloid P component sensitive to Shiga toxin 2. PLoS One (2011) 0.81

Programmed phosphorylation of histone H2AX precedes a phase of DNA double-strand break-independent synapsis in mouse meiosis. Reproduction (2012) 0.81

The increased expression of proteins involved in proliferation, DNA repair and DNA methylation in spleen of mice exposed to E. coli O157:H7 lipopolysaccharide. Environ Mol Mutagen (2013) 0.80

Effects of intestinal bacteria on the development of colonic neoplasm II. Changes in the immunological environment. Eur J Cancer Prev (1999) 0.78

Articles by these authors

(truncated to the top 100)

Methods for the synthesis of qualitative research: a critical review. BMC Med Res Methodol (2009) 4.69

NCCN Clinical Practice Guidelines in Oncology: colon cancer. J Natl Compr Canc Netw (2009) 4.41

Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol (2006) 4.27

A systematic review of barriers to and facilitators of the use of evidence by policymakers. BMC Health Serv Res (2014) 3.49

NCCN Clinical Practice Guidelines in Oncology: rectal cancer. J Natl Compr Canc Netw (2009) 3.37

Phase II study of erlotinib in patients with advanced biliary cancer. J Clin Oncol (2006) 3.31

Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer. JAMA (2007) 2.84

Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803. J Clin Oncol (2008) 2.74

Association of family history with cancer recurrence and survival among patients with stage III colon cancer. JAMA (2008) 2.67

A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci U S A (2007) 2.60

Phase II study of Erlotinib (OSI-774) in patients with advanced hepatocellular cancer. J Clin Oncol (2005) 2.56

Clarifying differences between review designs and methods. Syst Rev (2012) 2.39

Meiotic arrest and aneuploidy in MLH3-deficient mice. Nat Genet (2002) 2.39

Psychosocial interventions for supporting women to stop smoking in pregnancy. Cochrane Database Syst Rev (2013) 2.33

3D echocardiography: a review of the current status and future directions. J Am Soc Echocardiogr (2007) 2.12

Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. Int J Cancer (2010) 2.10

DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models. Cancer Res (2007) 1.79

Pathogen-induced systemic plant signal triggers DNA rearrangements. Nature (2003) 1.77

A randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain. Pain (2009) 1.64

Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location. Proc Natl Acad Sci U S A (2008) 1.62

A call for full public disclosure and moratorium on donation after cardiac death in children. Pediatr Crit Care Med (2010) 1.54

Systematic reviews and their application to research in speech and language therapy: a response to T. R. Pring's 'Ask a silly question: two decades of troublesome trials' (2004). Int J Lang Commun Disord (2005) 1.51

Measurements of methane emissions at natural gas production sites in the United States. Proc Natl Acad Sci U S A (2013) 1.44

Heat-killed bacteria induce genome instability in mouse small intestine, liver and spleen tissues. Cell Cycle (2009) 1.43

Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control. J Biol Chem (2009) 1.42

Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure. Mutat Res (2007) 1.34

Assessment of contractility of purified smooth muscle cells derived from embryonic stem cells. Stem Cells (2006) 1.29

Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo. Carcinogenesis (2007) 1.26

Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner. Environ Mol Mutagen (2009) 1.24

Developing evidence-based recommendations in public health--incorporating the views of practitioners, service users and user representatives. Health Expect (2008) 1.23

Role of ferritin alterations in human breast cancer cells. Breast Cancer Res Treat (2011) 1.22

Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. Cancer Biol Ther (2006) 1.22

Small molecules with big effects: the role of the microRNAome in cancer and carcinogenesis. Mutat Res (2010) 1.19

Survival after valve replacement for aortic stenosis: implications for decision making. J Thorac Cardiovasc Surg (2008) 1.19

A BEME systematic review of UK undergraduate medical education in the general practice setting: BEME Guide No. 32. Med Teach (2015) 1.18

Dose-dependence, sex- and tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes. Biochem Biophys Res Commun (2004) 1.16

In vivo bystander effect: cranial X-irradiation leads to elevated DNA damage, altered cellular proliferation and apoptosis, and increased p53 levels in shielded spleen. Int J Radiat Oncol Biol Phys (2008) 1.16

Epigenetic profiling of multidrug-resistant human MCF-7 breast adenocarcinoma cells reveals novel hyper- and hypomethylated targets. Mol Cancer Ther (2007) 1.13

Innate stimuli accentuate end-organ damage by nephrotoxic antibodies via Fc receptor and TLR stimulation and IL-1/TNF-alpha production. J Immunol (2006) 1.13

Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus. Mol Cancer Res (2005) 1.13

Is consumer response to plain/standardised tobacco packaging consistent with framework convention on tobacco control guidelines? A systematic review of quantitative studies. PLoS One (2013) 1.13

The conservative management of interstitial pregnancy. BJOG (2004) 1.13

The effects of the school environment on student health: a systematic review of multi-level studies. Health Place (2012) 1.12

Molecular aspects of plant adaptation to life in the Chernobyl zone. Plant Physiol (2004) 1.09

The school environment and student health: a systematic review and meta-ethnography of qualitative research. BMC Public Health (2013) 1.09

The role of miRNA in the direct and indirect effects of ionizing radiation. Radiat Environ Biophys (2011) 1.08

Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice. Cell Cycle (2008) 1.08

The impact of a simple, low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensive care unit. J Intensive Care Med (2009) 1.08

Non-targeted radiation effects-an epigenetic connection. Mutat Res (2011) 1.07

IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production. EMBO J (2013) 1.06

The First-aid Advice and Safety Training (FAST) parents programme for the prevention of unintentional injuries in preschool children: a protocol. Inj Prev (2013) 1.06

DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation. Cell Cycle (2008) 1.05

Epigenetic changes in patients with multiple sclerosis. Nat Rev Neurol (2012) 1.05

Protocol for a systematic review of the effects of schools and school-environment interventions on health: evidence mapping and syntheses. BMC Public Health (2011) 1.04

Integrating patient reported outcomes with clinical cancer registry data: a feasibility study of the electronic Patient-Reported Outcomes From Cancer Survivors (ePOCS) system. J Med Internet Res (2013) 1.04

Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal cortex in a mouse model. Mutat Res (2010) 1.04

Advection of surface-derived organic carbon fuels microbial reduction in Bangladesh groundwater. Proc Natl Acad Sci U S A (2013) 1.03

Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis. Carcinogenesis (2006) 1.03

Genome stability of vtc1, tt4, and tt5 Arabidopsis thaliana mutants impaired in protection against oxidative stress. Plant J (2004) 1.03

Epigenetic dysregulation underlies radiation-induced transgenerational genome instability in vivo. Int J Radiat Oncol Biol Phys (2006) 1.03

Formation of disulfide bond in p53 correlates with inhibition of DNA binding and tetramerization. Antioxid Redox Signal (2003) 1.02

NCCN clinical practice guidelines in oncology. Anal carcinoma. J Natl Compr Canc Netw (2010) 1.00

Donation after cardiocirculatory death: a call for a moratorium pending full public disclosure and fully informed consent. Philos Ethics Humanit Med (2011) 1.00

Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring. PLoS One (2013) 1.00

#CochraneTech: technology and the future of systematic reviews. Cochrane Database Syst Rev (2014) 0.99

Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes. BMC Med (2014) 0.99

Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism. Biochem Biophys Res Commun (2008) 0.99

Policy and public health recommendations to promote the initiation and duration of breast-feeding in developed country settings. Public Health Nutr (2009) 0.99

Hypomethylation and genome instability in the germline of exposed parents and their progeny is associated with altered miRNA expression. Carcinogenesis (2009) 0.98

The second murine autoantibody workshop: remarkable interlaboratory concordance for radiobinding assays to identify insulin autoantibodies in nonobese diabetic mice. Ann N Y Acad Sci (2003) 0.98

Chondroblastoma with associated aneurysmal bone cyst of the cuboid. J Foot Ankle Surg (2005) 0.98

Sex- and tissue-specific expression of maintenance and de novo DNA methyltransferases upon low dose X-irradiation in mice. Biochem Biophys Res Commun (2004) 0.98

A phase I trial of CEP-701 + gemcitabine in patients with advanced adenocarcinoma of the pancreas. Invest New Drugs (2008) 0.98

Use of remote sensing and geographic information systems to predict locations of Anopheles darlingi-positive breeding sites within the Sibun River in Belize, Central America. J Med Entomol (2006) 0.97

Systemic plant signal triggers genome instability. Plant J (2004) 0.97

Predicting pain and disability in patients with hand fractures: comparing pain anxiety, anxiety sensitivity and pain catastrophizing. Eur J Pain (2009) 0.97

Selective brain responses to acute and chronic low-dose X-ray irradiation in males and females. Biochem Biophys Res Commun (2004) 0.96

Stable loss of global DNA methylation in the radiation-target tissue--a possible mechanism contributing to radiation carcinogenesis? Biochem Biophys Res Commun (2005) 0.96

Standardized mean differences in individually-randomized and cluster-randomized trials, with applications to meta-analysis. Clin Trials (2005) 0.96

Paternal cranial irradiation induces distant bystander DNA damage in the germline and leads to epigenetic alterations in the offspring. Cell Cycle (2008) 0.95

Regulation of tissue inhibitor of metalloproteinase 1 gene transcription by RUNX1 and RUNX2. J Biol Chem (2004) 0.95

Crucial role for early growth response-1 in the transcriptional regulation of miR-20b in breast cancer. Oncotarget (2013) 0.94

Transcriptome profiling reveals similarities and differences in plant responses to cadmium and lead. Mutat Res (2005) 0.94

Biological characterization of sulfoxaflor, a novel insecticide. Pest Manag Sci (2010) 0.94

Transcriptome analysis reveals fundamental differences in plant response to acute and chronic exposure to ionizing radiation. Mutat Res (2007) 0.93

Intracardiac echocardiography during catheter ablation of atrial fibrillation. Europace (2008) 0.92

Obstructive sleep apnea screening and postoperative mortality in a large surgical cohort. Sleep Med (2013) 0.92

Parental enrichment and offspring development: modifications to brain, behavior and the epigenome. Behav Brain Res (2011) 0.92

Comparing midwife-led and doctor-led maternity care: a systematic review of reviews. J Adv Nurs (2012) 0.91

Intense THz pulses cause H2AX phosphorylation and activate DNA damage response in human skin tissue. Biomed Opt Express (2013) 0.90

Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals. Aging (Albany NY) (2011) 0.90

Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond. Front Genet (2013) 0.90

An empirical assessment of boarding and quality of care: delays in care among chest pain, pneumonia, and cellulitis patients. Acad Emerg Med (2011) 0.90

Radiation-induced bystander effects in vivo are sex specific. Mutat Res (2008) 0.90

Bone marrow mononuclear cell therapy for patients with cirrhosis: a Phase 1 study. Liver Int (2011) 0.90

Crossing the aortic valve in severe aortic stenosis: no longer acceptable? J Heart Valve Dis (2004) 0.89

Radiation-induced molecular changes in rat mammary tissue: possible implications for radiation-induced carcinogenesis. Int J Radiat Biol (2006) 0.89

Prenatal bystander stress alters brain, behavior, and the epigenome of developing rat offspring. Dev Neurosci (2011) 0.89

The views of young children in the UK about obesity, body size, shape and weight: a systematic review. BMC Public Health (2011) 0.89

Tricuspid regurgitation and implantable devices. Pacing Clin Electrophysiol (2014) 0.89