Published in Dev Biol on August 02, 2013
Developing and regenerating a sense of taste. Curr Top Dev Biol (2015) 0.87
Hedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation. J Neurophysiol (2014) 0.87
Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Development (2014) 0.87
Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds. Cancer Med (2014) 0.85
Progress and renewal in gustation: new insights into taste bud development. Development (2015) 0.83
Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma. Oncologist (2016) 0.82
β-Catenin Signaling Biases Multipotent Lingual Epithelial Progenitors to Differentiate and Acquire Specific Taste Cell Fates. PLoS Genet (2015) 0.81
The endocrinology of taste receptors. Nat Rev Endocrinol (2015) 0.80
Taste Bud Labeling in Whole Tongue Epithelial Sheet in Adult Mice. Tissue Eng Part C Methods (2016) 0.80
Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle. Nat Commun (2014) 0.79
The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells. PLoS Genet (2014) 0.77
Contribution of Underlying Connective Tissue Cells to Taste Buds in Mouse Tongue and Soft Palate. PLoS One (2016) 0.77
β-Catenin signaling regulates temporally discrete phases of anterior taste bud development. Development (2015) 0.75
Insulin-Like Growth Factors Are Expressed in the Taste System, but Do Not Maintain Adult Taste Buds. PLoS One (2016) 0.75
Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling. PLoS Genet (2016) 0.75
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AP1 transcription factors are required to maintain the peripheral taste system. Cell Death Dis (2016) 0.75
Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet (2017) 0.75
Sonic Hedgehog from both nerves and epithelium is a key trophic factor for taste bud maintenance. Development (2017) 0.75
FGF signaling refines Wnt gradients to regulate the patterning of taste papillae. Development (2017) 0.75
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Renewal of cells within taste buds. J Cell Biol (1965) 2.54
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Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate. Stem Cells (2009) 1.80
Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae. Dev Biol (2003) 1.69
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Fate mapping of mammalian embryonic taste bud progenitors. Development (2009) 1.20
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Shh and Ptc are associated with taste bud maintenance in the adult mouse. Mech Dev (2001) 1.08
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Taste bud cell dynamics during normal and sodium-restricted development. J Comp Neurol (2004) 0.97
Stem and progenitor cell compartments within adult mouse taste buds. Eur J Neurosci (2010) 0.91
Neuron/target matching between chorda tympani neurons and taste buds during postnatal rat development. J Neurobiol (2000) 0.91
Neural crest contribution to lingual mesenchyme, epithelium and developing taste papillae and taste buds. Dev Biol (2012) 0.86
Basal cell carcinoma and the carcinogenic role of aberrant Hedgehog signaling. Future Oncol (2010) 0.85
Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem (2002) 7.74
The deepest divergences in land plants inferred from phylogenomic evidence. Proc Natl Acad Sci U S A (2006) 3.10
Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev (2006) 3.09
Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med (2009) 2.99
Dual and opposing roles of primary cilia in medulloblastoma development. Nat Med (2009) 2.73
Epithelial hedgehog signals pattern the intestinal crypt-villus axis. Development (2004) 2.62
Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes Dev (2003) 2.59
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells. Development (2011) 2.45
Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling. Nat Genet (2008) 2.45
Wnt-beta-catenin signaling initiates taste papilla development. Nat Genet (2006) 2.43
TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation. Cell (2010) 2.32
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol (2007) 2.26
Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev (2003) 2.12
Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin. J Invest Dermatol (2009) 2.06
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development (2008) 1.96
A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2. Hum Mol Genet (2005) 1.89
Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle. Genes Dev (2004) 1.84
Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology (2009) 1.76
The magnitude of hedgehog signaling activity defines skin tumor phenotype. EMBO J (2003) 1.72
ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis. Biochem Biophys Res Commun (2003) 1.70
Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations. J Clin Invest (2011) 1.65
Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nat Genet (2010) 1.63
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A (2007) 1.54
Prospective identification of a multilineage progenitor in murine stomach epithelium. Gastroenterology (2007) 1.45
Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality. J Cell Biol (2006) 1.44
p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. J Clin Invest (2010) 1.41
Assessing atomistic and coarse-grained force fields for protein-lipid interactions: the formidable challenge of an ionizable side chain in a membrane. J Phys Chem B (2008) 1.37
Contrasting trajectories of heroin, cocaine, and methamphetamine use. J Addict Dis (2008) 1.34
Is arginine charged in a membrane? Biophys J (2007) 1.33
Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate. Dev Biol (2007) 1.32
Deconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk. Physiol Genomics (2007) 1.27
The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment. Blood (2008) 1.27
Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells. EMBO Mol Med (2012) 1.27
Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol (2011) 1.23
Hedgehog signaling regulates sebaceous gland development. Am J Pathol (2003) 1.23
Hedgehog-responsive mesenchymal clusters direct patterning and emergence of intestinal villi. Proc Natl Acad Sci U S A (2012) 1.20
Lipopolysaccharide-induced expression of multiple alternatively spliced MEFV transcripts in human synovial fibroblasts: a prominent splice isoform lacks the C-terminal domain that is highly mutated in familial Mediterranean fever. Arthritis Rheum (2004) 1.20
Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis. Development (2011) 1.18
Comparing the dynamic course of heroin, cocaine, and methamphetamine use over 10 years. Addict Behav (2008) 1.18
Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria. Gastroenterology (2010) 1.17
Villin: A marker for development of the epithelial pyloric border. Dev Dyn (2002) 1.15
Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype. Cancer Res (2002) 1.15
Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis. J Invest Dermatol (2012) 1.14
Client and program factors associated with dropout from court mandated drug treatment. Eval Program Plann (2008) 1.14
Pyrin and ASC co-localize to cellular sites that are rich in polymerizing actin. Exp Biol Med (Maywood) (2009) 1.09
Current molecular markers for gastric progenitor cells and gastric cancer stem cells. J Gastroenterol (2011) 1.05
Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion. Neoplasia (2008) 1.04
Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways. Am J Pathol (2009) 1.04
Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1. Hum Mol Genet (2007) 1.03
Kinetic properties of ASC protein aggregation in epithelial cells. J Cell Physiol (2010) 1.03
Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways. PLoS Med (2008) 1.02
Requirement of the forkhead gene Foxe1, a target of sonic hedgehog signaling, in hair follicle morphogenesis. Hum Mol Genet (2004) 1.02
Hedgehog signaling controls homeostasis of adult intestinal smooth muscle. Dev Biol (2011) 1.01
Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol (2013) 1.01
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Dynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn (2009) 1.00
Treatment entry barriers among California's Proposition 36 offenders. J Subst Abuse Treat (2008) 0.99
Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice. Gastroenterology (2013) 0.98
Following the hedgehog to new cancer therapies. N Engl J Med (2009) 0.94
Lack of evidence for activation of the hedgehog pathway in psoriasis. J Invest Dermatol (2008) 0.94
The mitochondrial genomes of the early land plants Treubia lacunosa and Anomodon rugelii: dynamic and conservative evolution. PLoS One (2011) 0.93
Familial Mediterranean fever in the post-genomic era: how an ancient disease is providing new insights into inflammatory pathways. Curr Drug Targets Inflamm Allergy (2005) 0.93
The complete mitochondrial genome sequence of the hornwort Phaeoceros laevis: retention of many ancient pseudogenes and conservative evolution of mitochondrial genomes in hornworts. Curr Genet (2009) 0.93
Simple liquid models with corrected dielectric constants. J Phys Chem B (2012) 0.92
Intestinal specific overexpression of interleukin-7 attenuates the alternation of intestinal intraepithelial lymphocytes after total parenteral nutrition administration. Ann Surg (2008) 0.91
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia. Am J Pathol (2012) 0.90
Pyrin, product of the MEFV locus, interacts with the proapoptotic protein, Siva. J Cell Physiol (2008) 0.90
Helicobacter-induced intestinal metaplasia in the stomach correlates with Elk-1 and serum response factor induction of villin. J Biol Chem (2004) 0.90
Psychometric properties of the Chinese version of the Parental Bonding Instrument. Int J Nurs Stud (2010) 0.90
Pyrin Modulates the Intracellular Distribution of PSTPIP1. PLoS One (2009) 0.89
Effect and mechanism of 5-aminolevulinic acid-mediated photodynamic therapy in esophageal cancer. Lasers Med Sci (2010) 0.89
Odontogenic keratocysts arise from quiescent epithelial rests and are associated with deregulated hedgehog signaling in mice and humans. Am J Pathol (2006) 0.88
The mitochondrial genome of the lycophyte Huperzia squarrosa: the most archaic form in vascular plants. PLoS One (2012) 0.88
Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development (2013) 0.87
Novel inorganic-organic-layered structures: crystallographic understanding of both phase and morphology formations of one-dimensional CdE (E = S, Se, Te) nanorods in ethylenediamine. Inorg Chem (2003) 0.87
Hemolymphangioma of the chest wall: A rare case report. Oncol Lett (2012) 0.87
American indians/alaska natives and substance abuse treatment outcomes: positive signs and continuing challenges. J Addict Dis (2011) 0.87
Gli proteins up-regulate the expression of basonuclin in Basal cell carcinoma. Cancer Res (2004) 0.87
The Coprinus cinereus adherin Rad9 functions in Mre11-dependent DNA repair, meiotic sister-chromatid cohesion, and meiotic homolog pairing. Proc Natl Acad Sci U S A (2002) 0.86
Specific overexpression of IL-7 in the intestinal mucosa: the role in intestinal intraepithelial lymphocyte development. Am J Physiol Gastrointest Liver Physiol (2008) 0.85
Developmental timing of first drug treatment and 10-year patterns of drug use. J Subst Abuse Treat (2012) 0.84
Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Dev Biol (2011) 0.83
Explaining long-term outcomes among drug dependent mothers treated in women-only versus mixed-gender programs. J Subst Abuse Treat (2013) 0.83
The complete mitochondrial genome sequence of the liverwort Pleurozia purpurea reveals extremely conservative mitochondrial genome evolution in liverworts. Curr Genet (2009) 0.83
Upper gastrointestinal tract obstruction due to congenital duodenal diaphragm. Surg Radiol Anat (2006) 0.83
Perceived neighborhood safety, recovery capital, and successful outcomes among mothers 10 years after substance abuse treatment. Subst Use Misuse (2014) 0.83
Pd-Ni alloy nanoparticle/carbon nanofiber composites: preparation, structure, and superior electrocatalytic properties for sugar analysis. Anal Chem (2014) 0.81