Published in Development on August 14, 2013
Sensory hair cell development and regeneration: similarities and differences. Development (2015) 0.88
Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling. J Neurosci (2014) 0.86
Quantitative High-Resolution Cellular Map of the Organ of Corti. Cell Rep (2015) 0.84
Conserved role of Sonic Hedgehog in tonotopic organization of the avian basilar papilla and mammalian cochlea. Proc Natl Acad Sci U S A (2015) 0.80
Where hearing starts: the development of the mammalian cochlea. J Anat (2015) 0.79
Sensational placodes: neurogenesis in the otic and olfactory systems. Dev Biol (2014) 0.78
The Role of Atonal Factors in Mechanosensory Cell Specification and Function. Mol Neurobiol (2014) 0.78
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife (2016) 0.78
The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A (2015) 0.77
Insm1 promotes neurogenic proliferation in delaminated otic progenitors. Mech Dev (2015) 0.75
MiR-210 promotes sensory hair cell formation in the organ of corti. BMC Genomics (2016) 0.75
Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea. Front Mol Neurosci (2017) 0.75
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nat Neurosci (2008) 6.13
Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop. Science (2002) 3.93
Oscillations in notch signaling regulate maintenance of neural progenitors. Neuron (2008) 3.51
Thyroid gland tumor diagnosis at US elastography. Radiology (2005) 3.26
alpha-Klotho as a regulator of calcium homeostasis. Science (2007) 2.71
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation. Development (2004) 2.65
Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity (2008) 2.62
Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J Biol Chem (2003) 2.59
Oscillatory control of factors determining multipotency and fate in mouse neural progenitors. Science (2013) 2.56
Cervical lymph node metastases: diagnosis at sonoelastography--initial experience. Radiology (2007) 2.56
Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. J Neurosci (2010) 2.55
Potential for neural regeneration after neurotoxic injury in the adult mammalian retina. Proc Natl Acad Sci U S A (2004) 2.44
Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet (2003) 2.42
Dclk1 distinguishes between tumor and normal stem cells in the intestine. Nat Genet (2012) 2.33
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability. J Biol Chem (2005) 2.33
Retinal cell fate determination and bHLH factors. Semin Cell Dev Biol (2004) 2.33
Regenerative treatment for tympanic membrane perforation. Otol Neurotol (2011) 2.22
The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells. Genes Dev (2009) 2.19
Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition. Nat Neurosci (2008) 2.13
Real-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells. Proc Natl Acad Sci U S A (2006) 2.10
Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine. FEBS Lett (2003) 2.10
A mechanism for gene-environment interaction in the etiology of congenital scoliosis. Cell (2012) 2.08
Instability of Hes7 protein is crucial for the somite segmentation clock. Nat Genet (2004) 2.07
Math3 and NeuroD regulate amacrine cell fate specification in the retina. Development (2002) 2.07
Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev (2003) 1.93
High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly. J Neurosci (2006) 1.89
Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol (2006) 1.86
The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology (2004) 1.81
Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1. Mol Cell Biol (2005) 1.79
Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Mol Cell Biol (2003) 1.75
Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. J Mol Med (Berl) (2005) 1.61
Histologic characterization of rat vocal fold scarring. Ann Otol Rhinol Laryngol (2005) 1.61
Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev (2006) 1.60
Otx2 regulates subtype specification and neurogenesis in the midbrain. J Neurosci (2005) 1.59
Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev Cell (2007) 1.56
The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock. Dev Cell (2007) 1.54
HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. Blood (2002) 1.51
Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development (2008) 1.50
Compartmentalization established by claudin-11-based tight junctions in stria vascularis is required for hearing through generation of endocochlear potential. J Cell Sci (2004) 1.50
Regulation of retinal cell fate specification by multiple transcription factors. Brain Res (2007) 1.50
Persistent and high levels of Hes1 expression regulate boundary formation in the developing central nervous system. Development (2006) 1.48
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J Cell Biol (2009) 1.48
Multiple roles of Notch signaling in cochlear development. Dev Biol (2007) 1.48
Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas. J Clin Invest (2006) 1.48
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia. J Cell Biol (2004) 1.47
Histological study of acute vocal fold injury in a rat model. Ann Otol Rhinol Laryngol (2006) 1.47
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum. Proc Natl Acad Sci U S A (2007) 1.47
Immediate inflammatory response and scar formation in wounded vocal folds. Ann Otol Rhinol Laryngol (2006) 1.45
Visualization of embryonic neural stem cells using Hes promoters in transgenic mice. Mol Cell Neurosci (2005) 1.41
The basic helix-loop-helix genes Hesr1/Hey1 and Hesr2/Hey2 regulate maintenance of neural precursor cells in the brain. J Biol Chem (2003) 1.41
FGF induces oscillations of Hes1 expression and Ras/ERK activation. Curr Biol (2008) 1.40
A rat excised larynx model of vocal fold scar. J Speech Lang Hear Res (2009) 1.37
Intronic delay is essential for oscillatory expression in the segmentation clock. Proc Natl Acad Sci U S A (2011) 1.37
Temporal regulation of Cre recombinase activity in neural stem cells. Genesis (2006) 1.36
Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification. J Biol Chem (2004) 1.34
Inflammatory factor profiles one hour following vocal fold injury. Ann Otol Rhinol Laryngol (2008) 1.33
Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One (2008) 1.28
Pharmacological inhibition of Notch signaling in the mature guinea pig cochlea. Neuroreport (2007) 1.27
CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo. J Neurosci (2005) 1.26
Hes1 and Hes5 control the progenitor pool, intermediate lobe specification, and posterior lobe formation in the pituitary development. Mol Endocrinol (2007) 1.25
Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. Hear Res (2004) 1.24
Continuous neurogenesis in the adult forebrain is required for innate olfactory responses. Proc Natl Acad Sci U S A (2011) 1.24
Six1 is essential for early neurogenesis in the development of olfactory epithelium. Dev Biol (2007) 1.19
Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer. Gastrointest Endosc (2011) 1.18
Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells. J Biol Chem (2011) 1.17
The role of Hes genes in intestinal development, homeostasis and tumor formation. Development (2012) 1.16
Novel strategy for treatment of inner ears using a biodegradable gel. Laryngoscope (2005) 1.16
Dynamic regulation of Notch signaling in neural progenitor cells. Curr Opin Cell Biol (2009) 1.16
One-third of vertiginous episodes during the follow-up period are caused by benign paroxysmal positional vertigo in patients with Meniere's disease. Acta Otolaryngol (2014) 1.15
Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells. Blood (2011) 1.14
Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors. EMBO J (2005) 1.14
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling. J Exp Med (2012) 1.13
Regeneration of the vocal fold using autologous mesenchymal stem cells. Ann Otol Rhinol Laryngol (2003) 1.11
Vocal cord fixation caused by an impacted fish bone in hypopharynx: report of a rare case. Am J Otolaryngol (2007) 1.11
MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain. Genes Cells (2012) 1.10
Drug delivery to the cochlea using PLGA nanoparticles. Laryngoscope (2005) 1.10
Regenerative medicine of the trachea: the first human case. Ann Otol Rhinol Laryngol (2005) 1.09
Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells. Stem Cells (2008) 1.08
Maximizing functional photoreceptor differentiation from adult human retinal stem cells. Stem Cells (2010) 1.07
Accelerating the tempo of the segmentation clock by reducing the number of introns in the Hes7 gene. Cell Rep (2012) 1.07
Aging effects on vestibulo-ocular responses in C57BL/6 mice: comparison with alteration in auditory function. Audiol Neurootol (2005) 1.06
Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine. Biochem Biophys Res Commun (2005) 1.06
Collagen subtypes in human vocal folds. Ann Otol Rhinol Laryngol (2006) 1.06
Oscillations, clocks and segmentation. Curr Opin Genet Dev (2003) 1.06
Viscoelastic measurements of vocal folds using the linear skin rheometer. J Voice (2007) 1.06
Dynamic expression of notch signaling genes in neural stem/progenitor cells. Front Neurosci (2011) 1.06
A novel model for rapid induction of apoptosis in spiral ganglions of mice. Laryngoscope (2003) 1.05
Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development. Dev Biol (2011) 1.04
Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development (2012) 1.04