Published in PeerJ on August 29, 2013
PIP kinases define PI4,5P₂signaling specificity by association with effectors. Biochim Biophys Acta (2015) 0.88
Analysis of close associations of uropod-associated proteins in human T-cells using the proximity ligation assay. PeerJ (2013) 0.76
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell (2003) 6.46
Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization. J Cell Biol (1997) 1.84
Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes. Immunology (2004) 1.82
Bringing up the rear: defining the roles of the uropod. Nat Rev Mol Cell Biol (2009) 1.74
Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module. Nat Immunol (2009) 1.69
Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca(2+) signaling. J Cell Biol (2004) 1.51
Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis. J Biol Chem (2006) 1.51
Competition for talin results in trans-dominant inhibition of integrin activation. J Biol Chem (2004) 1.46
Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. J Cell Biol (2010) 1.40
Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis. Mol Biol Cell (2007) 1.27
In vivo analysis of uropod function during physiological T cell trafficking. J Immunol (2011) 1.15
Flotillins interact with PSGL-1 in neutrophils and, upon stimulation, rapidly organize into membrane domains subsequently accumulating in the uropod. PLoS One (2009) 1.13
Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement. J Cell Biol (2007) 1.12
Integrin-induced PIP5K1C kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration. Immunity (2010) 1.10
Phosphatidylinositol 4,5-bisphosphate: targeted production and signaling. Bioessays (2013) 1.07
PIPKI gamma 90 negatively regulates LFA-1-mediated adhesion and activation in antigen-induced CD4+ T cells. J Immunol (2010) 0.92
Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes. BMC Cell Biol (2011) 0.91
Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase. J Immunol (2007) 0.88
An isoform-specific PDZ-binding motif targets type I PIP5 kinase beta to the uropod and controls polarization of neutrophil-like HL60 cells. FASEB J (2010) 0.86
Evidence for chemokine-mediated coalescence of preformed flotillin hetero-oligomers in human T-cells. J Biol Chem (2012) 0.84
Sat-Nav for T cells: Role of PI3K isoforms and lipid phosphatases in migration of T lymphocytes. Immunol Lett (2011) 0.79
Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nat Cell Biol (2004) 4.29
Resolution of inflammation by retrograde chemotaxis of neutrophils in transgenic zebrafish. J Leukoc Biol (2006) 3.21
Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish. Dev Cell (2010) 3.19
Dichotomous role of the macrophage in early Mycobacterium marinum infection of the zebrafish. Cell Host Microbe (2007) 3.09
Regulating cell migration: calpains make the cut. J Cell Sci (2005) 3.03
Lyn is a redox sensor that mediates leukocyte wound attraction in vivo. Nature (2011) 2.54
Spatiotemporal photolabeling of neutrophil trafficking during inflammation in live zebrafish. J Leukoc Biol (2011) 2.22
Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome. Blood (2010) 2.15
Peptidylarginine deiminase 4 contributes to tumor necrosis factor α-induced inflammatory arthritis. Arthritis Rheumatol (2014) 2.14
Characterization of a membrane-based gradient generator for use in cell-signaling studies. Lab Chip (2006) 2.11
FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion. J Cell Biol (2009) 1.97
Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion. J Cell Biol (2008) 1.79
Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain. J Cell Sci (2002) 1.79
Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK). J Biol Chem (2010) 1.75
TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain. J Biol Chem (2006) 1.75
RACK1 regulates integrin-mediated adhesion, protrusion, and chemotactic cell migration via its Src-binding site. Mol Biol Cell (2003) 1.65
Progressive neurodegeneration in patients with primary immunodeficiency disease on IVIG treatment. Clin Immunol (2002) 1.64
Live imaging of chronic inflammation caused by mutation of zebrafish Hai1. J Cell Sci (2007) 1.59
Differentiated HL-60 cells are a valid model system for the analysis of human neutrophil migration and chemotaxis. Int J Biochem Cell Biol (2002) 1.58
A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment. Lab Chip (2008) 1.58
Neutrophil dysfunction in a family with a SAPHO syndrome-like phenotype. Arthritis Rheum (2008) 1.58
The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages. Blood (2014) 1.57
Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos. Cell Microbiol (2009) 1.45
Filopodial calcium transients regulate growth cone motility and guidance through local activation of calpain. Neuron (2003) 1.42
Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish. J Cell Biol (2012) 1.41
Rapid prototyping of arrayed microfluidic systems in polystyrene for cell-based assays. Anal Chem (2011) 1.39
Talin1 regulates TCR-mediated LFA-1 function. J Immunol (2006) 1.39
Characterization of zebrafish larval inflammatory macrophages. Dev Comp Immunol (2009) 1.37
Cell polarization mechanisms during directed cell migration. Nat Cell Biol (2005) 1.33
Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells. Exp Cell Res (2005) 1.31
Proteolysis of cortactin by calpain regulates membrane protrusion during cell migration. Mol Biol Cell (2005) 1.30
Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis. Mol Biol Cell (2007) 1.27
Calpain-mediated proteolysis of paxillin negatively regulates focal adhesion dynamics and cell migration. J Biol Chem (2011) 1.23
An arrayed high-content chemotaxis assay for patient diagnosis. Integr Biol (Camb) (2010) 1.22
TNF-alpha promotes a stop signal that inhibits neutrophil polarization and migration via a p38 MAPK pathway. J Leukoc Biol (2005) 1.17
Calpain proteases in cell adhesion and motility. Int Rev Cytol (2005) 1.14
Asymmetric localization of calpain 2 during neutrophil chemotaxis. Mol Biol Cell (2006) 1.14
Flotillins interact with PSGL-1 in neutrophils and, upon stimulation, rapidly organize into membrane domains subsequently accumulating in the uropod. PLoS One (2009) 1.13
Natural killer T-cell autoreactivity leads to a specialized activation state. Blood (2008) 1.11
Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays. Blood (2012) 1.11
Dual roles for Rac2 in neutrophil motility and active retention in zebrafish hematopoietic tissue. Dev Cell (2011) 1.11
Rational design of a ligand-controlled protein conformational switch. Proc Natl Acad Sci U S A (2013) 1.08
Innate immune response to Streptococcus iniae infection in zebrafish larvae. Infect Immun (2012) 1.05
Distinct signalling mechanisms mediate neutrophil attraction to bacterial infection and tissue injury. Cell Microbiol (2012) 1.04
RACK1 regulates Src activity and modulates paxillin dynamics during cell migration. Exp Cell Res (2007) 1.03
Hax1 regulates neutrophil adhesion and motility through RhoA. J Cell Biol (2011) 1.02
The PCH family member proline-serine-threonine phosphatase-interacting protein 1 targets to the leukocyte uropod and regulates directed cell migration. Mol Biol Cell (2008) 1.00
The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish. Development (2009) 1.00
Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids. Biochemistry (2007) 1.00
Expression analysis of the Theileria parva subtelomere-encoded variable secreted protein gene family. PLoS One (2009) 0.99
Actin-binding protein-1 interacts with WASp-interacting protein to regulate growth factor-induced dorsal ruffle formation. Mol Biol Cell (2009) 0.98
Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish. J Leukoc Biol (2013) 0.98
Zebrafish Entrapment By Restriction Array (ZEBRA) device: a low-cost, agarose-free zebrafish mounting technique for automated imaging. Lab Chip (2013) 0.98
Modulation of neutrophil function by a secreted mucinase of Escherichia coli O157:H7. PLoS Pathog (2009) 0.97
Spatiotemporal regulation of Src and its substrates at invadosomes. Eur J Cell Biol (2012) 0.97
Muscle degeneration and leukocyte infiltration caused by mutation of zebrafish Fad24. Dev Dyn (2009) 0.96
Contact-dependent T cell activation and T cell stopping require talin1. J Immunol (2011) 0.94
Ezrin/Radixin/Moesin proteins and flotillins cooperate to promote uropod formation in T cells. Front Immunol (2013) 0.94
The conserved C-terminal I/LWEQ module targets Talin1 to focal adhesions. Cell Motil Cytoskeleton (2006) 0.93
Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites. PLoS Pathog (2013) 0.92
PIPKI gamma 90 negatively regulates LFA-1-mediated adhesion and activation in antigen-induced CD4+ T cells. J Immunol (2010) 0.92
Selective and tunable gradient device for cell culture and chemotaxis study. Lab Chip (2009) 0.92
Rho kinase is required for CCR7-mediated polarization and chemotaxis of T lymphocytes. FEBS Lett (2003) 0.92
The role of microtubules in neutrophil polarity and migration in live zebrafish. J Cell Sci (2012) 0.92
Human phagocyte defect caused by a Rac2 mutation detected by means of neonatal screening for T-cell lymphopenia. J Allergy Clin Immunol (2010) 0.91
Analysis of neutrophil chemotaxis. Methods Mol Biol (2007) 0.91
Citrullination of fibronectin modulates synovial fibroblast behavior. Arthritis Res Ther (2012) 0.91
Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes. BMC Cell Biol (2011) 0.91
Src-mediated phosphorylation of mammalian Abp1 (DBNL) regulates podosome rosette formation in transformed fibroblasts. J Cell Sci (2012) 0.90
Impaired podosome formation and invasive migration of macrophages from patients with a PSTPIP1 mutation and PAPA syndrome. Arthritis Rheum (2010) 0.90
Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity. Proc Natl Acad Sci U S A (2009) 0.90
Neutrophil migration: moving from zebrafish models to human autoimmunity. Immunol Rev (2013) 0.90
The SH2-domain-containing inositol 5-phosphatase (SHIP) limits the motility of neutrophils and their recruitment to wounds in zebrafish. J Cell Sci (2012) 0.89
Integrins in cell migration. Methods Enzymol (2007) 0.89
Characterizing asthma from a drop of blood using neutrophil chemotaxis. Proc Natl Acad Sci U S A (2014) 0.89
Kit-On-A-Lid-Assays for accessible self-contained cell assays. Lab Chip (2013) 0.88
Neutrophil reverse migration becomes transparent with zebrafish. Adv Hematol (2012) 0.87
Leukocyte migration from a fish eye's view. J Cell Sci (2012) 0.87
Enhanced activity of meprin-α, a pro-migratory and pro-angiogenic protease, in colorectal cancer. PLoS One (2011) 0.87
Imaging podosome dynamics and matrix degradation. Methods Mol Biol (2011) 0.85
Ezrin/moesin in motile Walker 256 carcinosarcoma cells: signal-dependent relocalization and role in migration. Exp Cell Res (2007) 0.85
The calpain small subunit regulates cell-substrate mechanical interactions during fibroblast migration. J Cell Sci (2008) 0.85
Neutrophil motility in vivo using zebrafish. Methods Mol Biol (2009) 0.85
Thalidomide for severe systemic onset juvenile rheumatoid arthritis: A multicenter study. J Pediatr (2004) 0.85
Evidence for chemokine-mediated coalescence of preformed flotillin hetero-oligomers in human T-cells. J Biol Chem (2012) 0.84
The actin regulatory protein HS1 interacts with Arp2/3 and mediates efficient neutrophil chemotaxis. J Biol Chem (2012) 0.84
Adhesions ring: a structural comparison between podosomes and the immune synapse. Eur J Cell Biol (2008) 0.84
Calpain inhibition impairs TNF-alpha-mediated neutrophil adhesion, arrest and oxidative burst. Mol Immunol (2009) 0.83
Expression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.83
The focal adhesion kinase inhibitor PF-562,271 impairs primary CD4+ T cell activation. Biochem Pharmacol (2013) 0.83
Neutrophil chemotaxis in a patient with neonatal-onset multisystem inflammatory disease and Muckle-Wells syndrome. Ann Allergy Asthma Immunol (2005) 0.82
A live imaging cell motility screen identifies prostaglandin E2 as a T cell stop signal antagonist. J Immunol (2011) 0.81
Interstitial leukocyte migration in vivo. Curr Opin Cell Biol (2013) 0.81
Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during T cell/antigen-presenting cell interactions. J Biol Chem (2009) 0.81
Specific roles of Rac1 and Rac2 in motile functions of HT1080 fibrosarcoma cells. Biochem Biophys Res Commun (2009) 0.80
Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells. PLoS One (2010) 0.80
WRAMPing up calcium in migrating cells by localized ER transport. Dev Cell (2013) 0.79