Published in PLoS One on August 27, 2013
Organizational metrics of interchromatin speckle factor domains: integrative classifier for stem cell adhesion & lineage signaling. Integr Biol (Camb) (2015) 0.80
Three-dimensional, soft neotissue arrays as high throughput platforms for the interrogation of engineered tissue environments. Biomaterials (2015) 0.76
Visualization of Compartmentalized Kinase Activity Dynamics Using Adaptable BimKARs. Chem Biol (2015) 0.75
Multilineage potential of adult human mesenchymal stem cells. Science (1999) 66.19
Matrix elasticity directs stem cell lineage specification. Cell (2006) 43.00
The green fluorescent protein. Annu Rev Biochem (1998) 34.17
Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell (2002) 19.15
Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol (2005) 11.74
Concern Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet (2011) 11.45
Clinical transplantation of a tissue-engineered airway. Lancet (2008) 10.04
FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat Cell Biol (2004) 9.31
Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol (2006) 8.52
Growth factors, matrices, and forces combine and control stem cells. Science (2009) 8.46
Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res (2000) 7.87
Regulation, substrates and functions of src. Biochim Biophys Acta (1996) 5.45
Mechanically activated integrin switch controls alpha5beta1 function. Science (2009) 4.94
Visualizing the mechanical activation of Src. Nature (2005) 4.63
Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem (2007) 3.87
Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proc Natl Acad Sci U S A (2008) 3.04
Potential risks of bone marrow cell transplantation into infarcted hearts. Blood (2007) 2.97
Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone. Endocrinology (1994) 2.62
Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: cross talk with the osteoblastogenic program. Cell Mol Life Sci (2009) 2.35
Structural basis for selective inhibition of Src family kinases by PP1. Chem Biol (1999) 2.35
Fluorescence proteins, live-cell imaging, and mechanobiology: seeing is believing. Annu Rev Biomed Eng (2008) 2.16
Multipotent stromal cells derived from the infrapatellar fat pad of the knee. Clin Orthop Relat Res (2003) 2.10
Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors. Proc Natl Acad Sci U S A (2008) 1.97
Phospho-regulation of Beta-catenin adhesion and signaling functions. Physiology (Bethesda) (2007) 1.89
Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition. Curr Opin Cell Biol (2005) 1.85
Decreased c-Src expression enhances osteoblast differentiation and bone formation. J Cell Biol (2000) 1.77
Src and focal adhesion kinase as therapeutic targets in cancer. Curr Opin Pharmacol (2008) 1.69
SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading. Mol Cell Biol (2002) 1.61
Focal adhesion kinase signaling pathways regulate the osteogenic differentiation of human mesenchymal stem cells. Exp Cell Res (2006) 1.55
Focal adhesion kinase signaling regulates cardiogenesis of embryonic stem cells. J Biol Chem (2005) 1.33
FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/beta-catenin signaling-dependent Runx2 expression. FASEB J (2008) 1.23
Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells. J Cell Physiol (2009) 1.21
Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery. Adv Drug Deliv Rev (2010) 1.18
Visualization of Src activity at different compartments of the plasma membrane by FRET imaging. Chem Biol (2009) 1.18
Versican V1 isoform induces neuronal differentiation and promotes neurite outgrowth. Mol Biol Cell (2004) 1.17
v-Src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts. Oncogene (1995) 1.16
Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation. Mol Cell Biol (2005) 1.12
Activation of FAK is necessary for the osteogenic differentiation of human mesenchymal stem cells on laminin-5. J Cell Biochem (2007) 1.11
Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types. Exp Hematol (2006) 1.09
Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells. Stem Cells (2009) 1.08
Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer. Nat Commun (2011) 1.06
Stem cells, microenvironment mechanics, and growth factor activation. Curr Opin Cell Biol (2009) 1.04
Development of FRET assay into quantitative and high-throughput screening technology platforms for protein-protein interactions. Ann Biomed Eng (2010) 1.03
Mechanisms for osteogenic differentiation of human mesenchymal stem cells induced by fluid shear stress. Biomech Model Mechanobiol (2010) 0.98
Genetic engineering for skeletal regenerative medicine. Annu Rev Biomed Eng (2007) 0.95
Laminin-1 induces neurite outgrowth in human mesenchymal stem cells in serum/differentiation factors-free conditions through activation of FAK-MEK/ERK signaling pathways. Biochem Biophys Res Commun (2009) 0.95
The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts. BMC Cancer (2010) 0.95
Embryonic stem cell-derived cardiomyogenesis: a novel role for calreticulin as a regulator. Stem Cells (2009) 0.93
Differentiation of C2C12 myoblasts is critically regulated by FAK signaling. Am J Physiol Regul Integr Comp Physiol (2005) 0.91
Critical roles of Src family tyrosine kinases in excitatory neuronal differentiation of cultured embryonic stem cells. Exp Cell Res (2006) 0.89
Suppression of c-Src activity stimulates muscle differentiation via p38 MAPK activation. Arch Biochem Biophys (2007) 0.87
Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton. Mol Med (1999) 0.87
Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells. Carcinogenesis (2012) 0.87
Regeneration of cartilage and bone by defined subsets of mesenchymal stromal cells--potential and pitfalls. Adv Drug Deliv Rev (2010) 0.86
Expanding the role of Src and protein-tyrosine phosphatases balance in modulating osteoblast metabolism: lessons from mice. Biochimie (2010) 0.82
Visualization of Src and FAK activity during the differentiation process from HMSCs to osteoblasts. PLoS One (2012) 0.82
Collagen gel three-dimensional matrices combined with adhesive proteins stimulate neuronal differentiation of mesenchymal stem cells. J R Soc Interface (2011) 0.82
The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat Immunol (2002) 11.22
The genome of the mesopolyploid crop species Brassica rapa. Nat Genet (2011) 8.23
The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19
Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science (2003) 6.85
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat Med (2010) 4.23
Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation. J Neurosci (2006) 3.84
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature (2013) 3.22
Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. Cancer Res (2002) 3.21
The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J Exp Med (2009) 3.17
Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells. Cancer Res (2006) 3.12
Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology (2011) 3.05
Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proc Natl Acad Sci U S A (2008) 3.04
Whole-genome sequence of Schistosoma haematobium. Nat Genet (2012) 2.91
A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo. Cell Metab (2006) 2.82
Altered ecosystem carbon and nitrogen cycles by plant invasion: a meta-analysis. New Phytol (2007) 2.68
JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. J Neurosci (2009) 2.64
Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis. Mol Cell (2013) 2.61
VGLUT2-dependent glutamate release from nociceptors is required to sense pain and suppress itch. Neuron (2010) 2.54
Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. Am J Respir Crit Care Med (2009) 2.53
The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells. J Clin Invest (2009) 2.52
Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors. Cancer Discov (2013) 2.43
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Nat Biotechnol (2011) 2.37
Targeted imaging of esophageal neoplasia with a fluorescently labeled peptide: first-in-human results. Sci Transl Med (2013) 2.30
IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma. J Immunol (2008) 2.17
Mesoscopic CH3NH3PbI3/TiO2 heterojunction solar cells. J Am Chem Soc (2012) 2.17
Ascaris suum draft genome. Nature (2011) 2.16
Rosuvastatin alleviates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome and MAPK pathways in a type 2 diabetes rat model. Cardiovasc Drugs Ther (2014) 2.16
Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts. Cancer Res (2010) 2.13
STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils. Blood (2006) 2.12
Human immunodeficiency virus (HIV)-negative plasmablastic lymphoma: a single institutional experience and literature review. Leuk Res (2011) 2.10
Risk Factors for Central Compartment Lymph Node Metastasis in Papillary Thyroid Microcarcinoma: A Meta-Analysis. World J Surg (2015) 2.09
Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. Gastroenterology (2004) 2.06
The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells. Proc Natl Acad Sci U S A (2002) 2.01
Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells. Proc Natl Acad Sci U S A (2011) 2.01
HS2 enhancer function is blocked by a transcriptional terminator inserted between the enhancer and the promoter. J Biol Chem (2004) 2.01
PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway. J Mol Cell Biol (2009) 2.00
Enhancement of learning and memory by elevating brain magnesium. Neuron (2010) 2.00
Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors. Proc Natl Acad Sci U S A (2008) 1.97
Incoherent-light temporal stretching of high-speed intensity waveforms. Opt Lett (2014) 1.96
CH4 and N2O emissions from Spartina alterniflora and Phragmites australis in experimental mesocosms. Chemosphere (2007) 1.91
Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions. J Biol Chem (2002) 1.89
Experience-dependent modification of a central amygdala fear circuit. Nat Neurosci (2013) 1.88
A geminivirus-related DNA mycovirus that confers hypovirulence to a plant pathogenic fungus. Proc Natl Acad Sci U S A (2010) 1.87
Atomic origins of the high catalytic activity of nanoporous gold. Nat Mater (2012) 1.87
Discovering transcription factor binding sites in highly repetitive regions of genomes with multi-read analysis of ChIP-Seq data. PLoS Comput Biol (2011) 1.86
Responses of ecosystem carbon cycle to experimental warming: a meta-analysis. Ecology (2013) 1.80
IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not. J Mol Med (Berl) (2009) 1.76
Competition between phasic and asynchronous release for recovered synaptic vesicles at developing hippocampal autaptic synapses. J Neurosci (2004) 1.76
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. Am J Pathol (2005) 1.76
Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights. PLoS Biol (2010) 1.74
Application of the level-set method to the implicit solvation of nonpolar molecules. J Chem Phys (2007) 1.73
Cyclin A2 mediates cardiomyocyte mitosis in the postmitotic myocardium. J Biol Chem (2004) 1.72
ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. Cancer Cell (2012) 1.71
Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in HCC. Liver Int (2013) 1.71
Human pregnancy up-regulates Tim-3 in innate immune cells for systemic immunity. J Immunol (2009) 1.68
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP. Hum Mol Genet (2011) 1.68
Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation. J Biol Chem (2007) 1.65
Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS One (2009) 1.65
Optimal vaccination strategies for 2009 pandemic H1N1 and seasonal influenza vaccines in humans. Vaccine (2010) 1.65
SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood (2008) 1.63
Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa. J Immunol (2006) 1.62
Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury. J Neurotrauma (2008) 1.62
Insights into salt tolerance from the genome of Thellungiella salsuginea. Proc Natl Acad Sci U S A (2012) 1.62
Moderate cardiac-selective overexpression of angiotensin II type 2 receptor protects cardiac functions from ischaemic injury. Exp Physiol (2011) 1.61
A facilitated tracking and transcription mechanism of long-range enhancer function. Nucleic Acids Res (2007) 1.60
Immediate autotransplantation of mandibular third molar in China. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 1.60
Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients. Clin Cancer Res (2009) 1.59
Mortality rates among prevalent hemodialysis patients in Beijing: a comparison with USRDS data. Nephrol Dial Transplant (2012) 1.59
Development of polydimethylsiloxane substrates with tunable elastic modulus to study cell mechanobiology in muscle and nerve. PLoS One (2012) 1.54
Ecosystem carbon stock influenced by plantation practice: implications for planting forests as a measure of climate change mitigation. PLoS One (2010) 1.51
Simultaneous visualization of protumorigenic Src and MT1-MMP activities with fluorescence resonance energy transfer. Cancer Res (2010) 1.50
Loss of melanopsin-containing retinal ganglion cells in a rat glaucoma model. Chin Med J (Engl) (2008) 1.48
A molecular and functional analysis of large granular lymphocyte expansions in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors. Leuk Lymphoma (2011) 1.47
Effects of a dental adhesive incorporating antibacterial monomer on the growth, adherence and membrane integrity of Streptococcus mutans. J Dent (2009) 1.46
Evaluation of de novo transcriptome assemblies from RNA-Seq data. Genome Biol (2014) 1.46
Electrostatic free energy and its variations in implicit solvent models. J Phys Chem B (2008) 1.45
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. J Clin Invest (2012) 1.44
Matrix metalloproteinases in human sclerotic dentine of attrited molars. Arch Oral Biol (2012) 1.42
Dual function of Arabidopsis ATAF1 in abiotic and biotic stress responses. Cell Res (2009) 1.41
Single molecule detection from a large-scale SERS-active Au₇₉Ag₂₁ substrate. Sci Rep (2011) 1.41
Small-for-size syndrome after living donor liver transplantation: successful treatment with a transjugular intrahepatic portosystemic shunt. Liver Transpl (2012) 1.41
Prophylaxis against hepatitis B virus recurrence after liver transplantation for hepatitis B virus-related end-stage liver diseases with severe hypersplenism and splenomegaly: role of splenectomy. J Surg Res (2012) 1.41
Effects of temperature on the development and population growth of the sycamore lace bug, Corythucha ciliata. J Insect Sci (2011) 1.41
Homozygous hemoglobin C disease. Blood (2013) 1.41
Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo. Clin Cancer Res (2005) 1.40
Long noncoding RNAs associated with liver regeneration 1 accelerates hepatocyte proliferation during liver regeneration by activating Wnt/β-catenin signaling. Hepatology (2013) 1.40
Neonatal Type II Alveolar Epithelial Cell Transplant Facilitates Lung Reparation in Piglets With Acute Lung Injury and Extracorporeal Life Support. Pediatr Crit Care Med (2016) 1.39
The significance of degenerate processes to enantioselective olefin metathesis reactions promoted by stereogenic-at-Mo complexes. J Am Chem Soc (2009) 1.37
Effects of flow patterns on the localization and expression of VE-cadherin at vascular endothelial cell junctions: in vivo and in vitro investigations. J Vasc Res (2005) 1.37
Vstm3 is a member of the CD28 family and an important modulator of T-cell function. Eur J Immunol (2011) 1.36
Responses of ecosystem nitrogen cycle to nitrogen addition: a meta-analysis. New Phytol (2010) 1.36
p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia. J Immunol (2004) 1.36
A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis. Dev Cell (2013) 1.36
Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4. Arthritis Rheum (2010) 1.36