Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity.

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Published in J Infect Dis on January 01, 2000


D W Vaughn1, S Green, S Kalayanarooj, B L Innis, S Nimmannitya, S Suntayakorn, T P Endy, B Raengsakulrach, A L Rothman, F A Ennis, A Nisalak

Author Affiliations

1: Department of Virus Diseases, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.

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The 40K activity of one gram of potassium. Phys Med Biol (1997) 2.48

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Effect of tumour necrosis factor on cultured human melanoma cells. Nature (1975) 2.46

Dengue virus identification by the plaque reduction neutralization test. J Immunol (1967) 2.45

Partial purification of a serum factor that causes necrosis of tumors. Proc Natl Acad Sci U S A (1976) 2.42

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A superfamily of potentially oncogenic hormone receptors. Nature (1987) 2.40

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Human cytotoxic T-cell memory: long-lived responses to vaccinia virus. J Virol (1996) 2.35

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