Published in J Neurosurg on September 27, 2013
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MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study. Lancet Neurol (2013) 2.37
Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem Biophys Res Commun (2005) 2.28
Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med Biol (2008) 2.17
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Antibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-beta plaque load in the TgCRND8 mouse model of Alzheimer's disease. PLoS One (2010) 2.03
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Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--results of different treatment protocols. Radiology (2007) 1.90
Uterine leiomyomas: MR imaging-based thermometry and thermal dosimetry during focused ultrasound thermal ablation. Radiology (2006) 1.89
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Microbubble contrast agent with focused ultrasound to create brain lesions at low power levels: MR imaging and histologic study in rabbits. Radiology (2006) 1.71
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Alzheimer disease in a mouse model: MR imaging-guided focused ultrasound targeted to the hippocampus opens the blood-brain barrier and improves pathologic abnormalities and behavior. Radiology (2014) 1.68
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Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo. J Cereb Blood Flow Metab (2006) 1.60
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Focused ultrasound surgery in oncology: overview and principles. Radiology (2011) 1.51
Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier. Ultrasound Med Biol (2006) 1.49
MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain. Magn Reson Med (2004) 1.47
Progress and problems in the application of focused ultrasound for blood-brain barrier disruption. Ultrasonics (2008) 1.42
Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--imaging predictors of success. Radiology (2008) 1.37
The impact of standing wave effects on transcranial focused ultrasound disruption of the blood-brain barrier in a rat model. Phys Med Biol (2010) 1.37
An MRI-compatible system for focused ultrasound experiments in small animal models. Med Phys (2009) 1.36
Targeted delivery of neural stem cells to the brain using MRI-guided focused ultrasound to disrupt the blood-brain barrier. PLoS One (2011) 1.35
Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma. Ultrasound Med Biol (2012) 1.29
A numerical study of transcranial focused ultrasound beam propagation at low frequency. Phys Med Biol (2005) 1.27
A novel method for the intracellular delivery of siRNA using microbubble-enhanced focused ultrasound. Biochem Biophys Res Commun (2005) 1.21
A magnetic resonance imaging-compatible, large-scale array for trans-skull ultrasound surgery and therapy. J Ultrasound Med (2005) 1.21
Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound. Exp Neurol (2013) 1.19
Multi-frequency characterization of the speed of sound and attenuation coefficient for longitudinal transmission of freshly excised human skulls. Phys Med Biol (2010) 1.19
Cavitation threshold of microbubbles in gel tunnels by focused ultrasound. Ultrasound Med Biol (2007) 1.18
Key factors that affect sonoporation efficiency in in vitro settings: the importance of standing wave in sonoporation. Biochem Biophys Res Commun (2007) 1.18
Image-guided neurosurgery at Brigham and Women's Hospital. IEEE Eng Med Biol Mag (2006) 1.14
Localised drug release using MRI-controlled focused ultrasound hyperthermia. Int J Hyperthermia (2010) 1.14
Focused-ultrasound disruption of the blood-brain barrier using closely-timed short pulses: influence of sonication parameters and injection rate. Ultrasound Med Biol (2011) 1.13
Influence of exposure time and pressure amplitude on blood-brain-barrier opening using transcranial ultrasound exposures. ACS Chem Neurosci (2010) 1.13
Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasound. Hum Gene Ther (2012) 1.12
Micro-receiver guided transcranial beam steering. IEEE Trans Ultrason Ferroelectr Freq Control (2002) 1.11
Focused ultrasound delivers targeted immune cells to metastatic brain tumors. Cancer Res (2013) 1.10
Correlation of ultrasound phase with physical skull properties. Ultrasound Med Biol (2002) 1.10
In vitro characterization of perfluorocarbon droplets for focused ultrasound therapy. Phys Med Biol (2010) 1.09
In vitro and in vivo high-intensity focused ultrasound thrombolysis. Invest Radiol (2012) 1.08
Induction of apoptosis in vivo in the rabbit brain with focused ultrasound and Optison. Ultrasound Med Biol (2006) 1.05
Ultrasound insertion loss of rat parietal bone appears to be proportional to animal mass at submegahertz frequencies. Ultrasound Med Biol (2011) 1.05
Transcranial ultrasound focus reconstruction with phase and amplitude correction. IEEE Trans Ultrason Ferroelectr Freq Control (2005) 1.04
Bio-acoustic thermal lensing and nonlinear propagation in focused ultrasound surgery using large focal spots: a parametric study. Phys Med Biol (2002) 1.04
Two-photon fluorescence microscopy study of cerebrovascular dynamics in ultrasound-induced blood-brain barrier opening. J Cereb Blood Flow Metab (2011) 1.04
Focused ultrasound effects on nerve action potential in vitro. Ultrasound Med Biol (2009) 1.03
A unified model for the speed of sound in cranial bone based on genetic algorithm optimization. Phys Med Biol (2002) 1.02
In vivo monitoring of focused ultrasound surgery using local harmonic motion. Ultrasound Med Biol (2008) 1.02
Contrast agent kinetics in the rabbit brain during exposure to therapeutic ultrasound. Ultrasound Med Biol (2010) 1.02
High-intensity focused ultrasound (HIFU) for dissolution of clots in a rabbit model of embolic stroke. PLoS One (2012) 1.01
Evaluation of referenceless thermometry in MRI-guided focused ultrasound surgery of uterine fibroids. J Magn Reson Imaging (2008) 1.00
Patterns of thermal deposition in the skull during transcranial focused ultrasound surgery. IEEE Trans Biomed Eng (2004) 0.99
Investigation of standing-wave formation in a human skull for a clinical prototype of a large-aperture, transcranial MR-guided focused ultrasound (MRgFUS) phased array: an experimental and simulation study. IEEE Trans Biomed Eng (2011) 0.99
A super-resolution ultrasound method for brain vascular mapping. Med Phys (2013) 0.99
Feasibility of using lateral mode coupling method for a large scale ultrasound phased array for noninvasive transcranial therapy. IEEE Trans Biomed Eng (2009) 0.98
Apoptosis signals in lymphoblasts induced by focused ultrasound. FASEB J (2004) 0.98
Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats. BMC Neurol (2010) 0.97
A PVDF receiver for ultrasound monitoring of transcranial focused ultrasound therapy. IEEE Trans Biomed Eng (2010) 0.97
Noninvasive thermal ablation of hepatocellular carcinoma by using magnetic resonance imaging-guided focused ultrasound. Gastroenterology (2004) 0.97
Heat-activated liposomal MR contrast agent: initial in vivo results in rabbit liver and kidney. Radiology (2004) 0.97
Temperature change near microbubbles within a capillary network during focused ultrasound. Phys Med Biol (2010) 0.97
MRI-based thermal dosimetry and diffusion-weighted imaging of MRI-guided focused ultrasound thermal ablation of uterine fibroids. J Magn Reson Imaging (2009) 0.96
Simulations and measurements of transcranial low-frequency ultrasound therapy: skull-base heating and effective area of treatment. Phys Med Biol (2011) 0.96
Transcranial passive acoustic mapping with hemispherical sparse arrays using CT-based skull-specific aberration corrections: a simulation study. Phys Med Biol (2013) 0.95
Noninvasive and targeted drug delivery to the brain using focused ultrasound. ACS Chem Neurosci (2013) 0.95
MRI monitoring of heating produced by ultrasound absorption in the skull: in vivo study in pigs. Magn Reson Med (2004) 0.95
In vivo MR elastography of the prostate gland using a transurethral actuator. Magn Reson Med (2009) 0.95
Mechanism of porphyrin-induced sonodynamic effect: possible role of hyperthermia. Radiat Res (2006) 0.94
Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound. Nanomedicine (2012) 0.94
Three-dimensional transcranial ultrasound imaging of microbubble clouds using a sparse hemispherical array. IEEE Trans Biomed Eng (2014) 0.94
Antitumor effects of combining docetaxel (taxotere) with the antivascular action of ultrasound stimulated microbubbles. PLoS One (2012) 0.94
Focused ultrasound for targeted delivery of siRNA and efficient knockdown of Htt expression. J Control Release (2012) 0.94
Intracellular delivery of Bak BH3 peptide by microbubble-enhanced ultrasound. Pharm Res (2005) 0.94
Ultrasound enhanced drug delivery to the brain and central nervous system. Int J Hyperthermia (2012) 0.93
Investigation of optimal method for inducing harmonic motion in tissue using a linear ultrasound phased array--a simulation study. Ultrason Imaging (2006) 0.92
Focal beam distortion and treatment planning in abdominal focused ultrasound surgery. Med Phys (2005) 0.92
Drug delivery to the brain by focused ultrasound induced blood-brain barrier disruption: quantitative evaluation of enhanced permeability of cerebral vasculature using two-photon microscopy. J Control Release (2013) 0.92
Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncology. Neurosurg Focus (2012) 0.91
Hyperthermia-mediated doxorubicin release from thermosensitive liposomes using MR-HIFU: therapeutic effect in rabbit Vx2 tumours. Int J Hyperthermia (2015) 0.91