PubRank

M E Selsted

Author PubWeight™ 160.14‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest 1985 8.63
2 Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol 2000 6.62
3 Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect Immun 1984 5.30
4 Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity. J Clin Invest 1989 5.21
5 A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science 1999 3.90
6 Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes. Proc Natl Acad Sci U S A 1990 3.90
7 Primary structures of three human neutrophil defensins. J Clin Invest 1985 3.70
8 Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J Biol Chem 1985 3.58
9 Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages. J Biol Chem 1983 3.00
10 Direct inactivation of viruses by human granulocyte defensins. J Virol 1986 3.00
11 Defensins. Eur J Haematol 1990 2.88
12 Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization. Science 1991 2.71
13 Monocyte-chemotactic activity of defensins from human neutrophils. J Clin Invest 1989 2.50
14 Defensins: endogenous antibiotic peptides of animal cells. Cell 1991 2.45
15 Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores. Protein Sci 1994 2.43
16 Structure, function, and membrane integration of defensins. Curr Opin Struct Biol 1995 2.40
17 Antibacterial activity of microbicidal cationic proteins 1 and 2, natural peptide antibiotics of rabbit lung macrophages. Infect Immun 1983 2.33
18 Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes. J Virol 1985 2.31
19 Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium. Infect Immun 1990 2.25
20 Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations. J Clin Invest 1988 2.18
21 Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin. Infect Immun 1987 2.16
22 Activity of rabbit leukocyte peptides against Candida albicans. Infect Immun 1985 2.05
23 Paneth cell defensins: endogenous peptide components of intestinal host defense. FASEB J 1996 2.03
24 In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes. Blood 1986 2.01
25 The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation. Mol Cell Biol 1998 1.98
26 Purification and in vitro activities of rabbit platelet microbicidal proteins. Infect Immun 1997 1.96
27 Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms. Infect Immun 1994 1.93
28 Neutrophils and host defense. Ann Intern Med 1988 1.92
29 Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity. Infect Immun 1985 1.89
30 In vitro killing of spores and hyphae of Aspergillus fumigatus and Rhizopus oryzae by rabbit neutrophil cationic peptides and bronchoalveolar macrophages. J Infect Dis 1986 1.84
31 Killing of Giardia lamblia by cryptdins and cationic neutrophil peptides. Infect Immun 1994 1.78
32 Sizing membrane pores in lipid vesicles by leakage of co-encapsulated markers: pore formation by melittin. Biophys J 1997 1.76
33 Bilayer interactions of indolicidin, a small antimicrobial peptide rich in tryptophan, proline, and basic amino acids. Biophys J 1997 1.68
34 Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity. J Immunol 1988 1.64
35 Structure and diversity of the murine cryptdin gene family. Genomics 1994 1.62
36 Defensin-rich dense granules of human neutrophils. Blood 1987 1.59
37 Increased content of microbicidal cationic peptides in rabbit alveolar macrophages elicited by complete Freund adjuvant. Infect Immun 1981 1.52
38 Antimicrobial activity of phagocyte granule proteins. Semin Respir Infect 1986 1.49
39 Purification and antimicrobial properties of three defensins from rat neutrophils. Infect Immun 1989 1.46
40 Defensins promote fusion and lysis of negatively charged membranes. Protein Sci 1993 1.43
41 Purification and primary structure of murine cryptdin-1, a Paneth cell defensin. FEBS Lett 1992 1.42
42 Human neutrophil-mediated nonoxidative antifungal activity against Cryptococcus neoformans. Infect Immun 2000 1.38
43 Defensins are mitogenic for epithelial cells and fibroblasts. J Cell Physiol 1993 1.35
44 Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins. J Biol Chem 1997 1.26
45 Oxygen-independent bactericidal systems. Mechanisms and disorders. Hematol Oncol Clin North Am 1988 1.21
46 CD spectra of indolicidin antimicrobial peptides suggest turns, not polyproline helix. Biochemistry 1999 1.19
47 Newborn rabbit alveolar macrophages are deficient in two microbicidal cationic peptides, MCP-1 and MCP-2. Am Rev Respir Dis 1985 1.17
48 Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes. Infect Immun 1999 1.16
49 Anti-HIV-1 activity of indolicidin, an antimicrobial peptide from neutrophils. J Leukoc Biol 1998 1.15
50 Lysozyme: primary bactericidin in human plasma serum active against Bacillus subtilis. Infect Immun 1978 1.15
51 Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins. Biochemistry 1995 1.14
52 In vitro sensitivity of oral, gram-negative, facultative bacteria to the bactericidal activity of human neutrophil defensins. Infect Immun 1990 1.13
53 Purification and characterization of human T-lymphocyte-derived erythroid-potentiating activity. J Biol Chem 1984 1.11
54 Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils. J Biol Chem 1993 1.11
55 Liposomal entrapment of the neutrophil-derived peptide indolicidin endows it with in vivo antifungal activity. Biochim Biophys Acta 1995 1.10
56 Solution structures of the rabbit neutrophil defensin NP-5. J Mol Biol 1988 1.09
57 Induction of epithelial chloride secretion by channel-forming cryptdins 2 and 3. Proc Natl Acad Sci U S A 1997 1.08
58 NMR studies of defensin antimicrobial peptides. 2. Three-dimensional structures of rabbit NP-2 and human HNP-1. Biochemistry 1992 1.07
59 Cryptdin gene expression in developing mouse small intestine. Am J Physiol 1997 1.07
60 Characterization of two crystal forms of neutrophil cationic protein NP2, a naturally occurring broad-spectrum antimicrobial agent from leukocytes. J Mol Biol 1984 1.05
61 Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis. J Immunol 1995 1.05
62 In vitro effect of phagocyte cationic peptides on Coccidioides immitis. J Infect Dis 1985 1.03
63 Interactions of monomeric rabbit neutrophil defensins with bilayers: comparison with dimeric human defensin HNP-2. Biochemistry 1996 1.03
64 Inhibition of protein kinase C by defensins, antibiotic peptides from human neutrophils. Biochem Pharmacol 1988 1.02
65 Susceptibility of human and murine Chlamydia trachomatis serovars to granulocyte- and epithelium-derived antimicrobial peptides. J Pept Res 2003 1.02
66 Identification of constituents of human neutrophil azurophil granules that mediate fungistasis against Histoplasma capsulatum. Infect Immun 2000 1.02
67 Two-dimensional NMR studies of the antimicrobial peptide NP-5. Biochemistry 1987 1.01
68 Synergistic cytolysis mediated by hydrogen peroxide combined with peptide defensins. Cell Immunol 1988 1.00
69 Synthesis and characterization of indolicidin, a tryptophan-rich antimicrobial peptide from bovine neutrophils. Int J Pept Protein Res 1995 1.00
70 Opsonic activity of MCP-1 and MCP-2, cationic peptides from rabbit alveolar macrophages. Diagn Microbiol Infect Dis 1985 1.00
71 Regulation of gene expression of myeloperoxidase during myeloid differentiation. J Cell Physiol 1988 0.97
72 A simple and ultrasensitive enzymatic assay for the quantitative determination of lysozyme in the picogram range. Anal Biochem 1980 0.97
73 Antimicrobial activity of rabbit leukocyte defensins against Treponema pallidum subsp. pallidum. Infect Immun 1991 0.97
74 Isolation and purification of bactericides from human tears. Exp Eye Res 1982 0.96
75 Peptide localization and gene structure of cryptdin 4, a differentially expressed mouse paneth cell alpha-defensin. Infect Immun 1999 0.96
76 Characterization of luminal paneth cell alpha-defensins in mouse small intestine. Attenuated antimicrobial activities of peptides with truncated amino termini. J Biol Chem 2000 0.95
77 Cloning and expression of bovine neutrophil beta-defensins. Biosynthetic profile during neutrophilic maturation and localization of mature peptide to novel cytoplasmic dense granules. J Biol Chem 1999 0.92
78 In vitro antimicrobial activity of defensins against ocular pathogens. Arch Ophthalmol 1990 0.92
79 Eosin Y: a reversible stain for detecting electrophoretically resolved protein. Anal Biochem 1986 0.91
80 Formation and characterization of a single Trp-Trp cross-link in indolicidin that confers protease stability without altering antimicrobial activity. J Biol Chem 2000 0.90
81 Synergistic activity of rabbit granulocyte peptides against Candida albicans. Infect Immun 1986 0.89
82 Characterization of two crystal forms of human defensin neutrophil cationic peptide 1, a naturally occurring antimicrobial peptide of leukocytes. J Biol Chem 1988 0.88
83 Fungicidal properties of defensin NP-1 and activity against Cryptococcus neoformans in vitro. Antimicrob Agents Chemother 1993 0.87
84 Bactericidal potency and mechanistic specificity of neutrophil defensins against bovine mastitis pathogens. Vet Microbiol 1991 0.87
85 Killing of oral, gram-negative, facultative bacteria by the rabbit defensin, NP-1. Oral Microbiol Immunol 1990 0.85
86 Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils. J Biol Chem 1996 0.85
87 Cryptdin-3 induces novel apical conductance(s) in Cl- secretory, including cystic fibrosis, epithelia. Am J Physiol Cell Physiol 2001 0.84
88 NMR studies of defensin antimicrobial peptides. 1. Resonance assignment and secondary structure determination of rabbit NP-2 and human HNP-1. Biochemistry 1992 0.84
89 Semidry electroblotting of peptides and proteins from acid-urea polyacrylamide gels. Anal Biochem 1997 0.83
90 Structure and dynamics of the neutrophil defensins NP-2, NP-5, and HNP-1: NMR studies of amide hydrogen exchange kinetics. Proteins 1994 0.82
91 Myeloperoxidase (MPO) gene mutation in hereditary MPO deficiency. Blood 1994 0.81
92 Divergent expression of cytotoxic and microbicidal functions of rabbit alveolar and peritoneal macrophages: effects of non-specific activation and a natural microbicidal peptide, MCP-1. Aust J Exp Biol Med Sci 1985 0.79
93 Evidence for a pretranslational defect in hereditary and acquired myeloperoxidase deficiency. Blood 1989 0.78
94 Microbicidal and cytotoxic properties of soluble components from quaternary aminoethyl-sephadex. Infect Immun 1980 0.75
95 In vitro activity of naturally occurring peptides (defensins) against Listeria monocytogenes. Cad Saude Publica 2003 0.75