Thomas Leung

Author PubWeight™ 35.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trial. JAMA 2010 4.71
2 Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse. J Neurosci 2004 1.66
3 Raf-1 regulates Rho signaling and cell migration. J Cell Biol 2005 1.58
4 A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow. Cell 2008 1.42
5 Detection of the siphon internal carotid artery stenosis: transcranial Doppler versus digital subtraction angiography. J Neuroimaging 2009 1.38
6 Characterization of RhoA-binding kinase ROKalpha implication of the pleckstrin homology domain in ROKalpha function using region-specific antibodies. J Biol Chem 2002 1.22
7 CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity. J Neurochem 2009 1.14
8 Treatment for hepatocellular carcinoma with portal vein tumor thrombosis: the emerging role for radioembolization using yttrium-90. Oncology 2013 1.12
9 Mypt1-mediated spatial positioning of Bmp2-producing cells is essential for liver organogenesis. Development 2008 1.10
10 Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation. J Biol Chem 2013 1.08
11 Rho-mediated assembly of stress fibers is differentially regulated in corneal fibroblasts and myofibroblasts. Exp Cell Res 2004 1.07
12 ArhGAP15, a novel human RacGAP protein with GTPase binding property. FEBS Lett 2003 1.03
13 From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-alpha kinase activity. J Cell Biol 2009 1.01
14 Geographic and sex difference in the distribution of intracranial atherosclerosis in China. Stroke 2013 0.99
15 Vimentin intermediate filament reorganization by Cdc42: involvement of PAK and p70 S6 kinase. Eur J Cell Biol 2002 0.97
16 Phosphorylation of myosin phosphatase targeting subunit 3 (MYPT3) and regulation of protein phosphatase 1 by protein kinase A. J Biol Chem 2006 0.94
17 Signal intensity ratio as a novel measure of hemodynamic significance for intracranial atherosclerosis. Int J Stroke 2013 0.94
18 Long-term prognosis of Chinese patients with a lacunar infarct associated with small vessel disease: a five-year longitudinal study. Int J Stroke 2009 0.90
19 Interobserver reproducibility of signal intensity ratio on magnetic resonance angiography for hemodynamic impact of intracranial atherosclerosis. J Stroke Cerebrovasc Dis 2013 0.90
20 Magnetic resonance angiography signal intensity as a marker of hemodynamic impairment in intracranial arterial stenosis. PLoS One 2013 0.89
21 Evaluation of age-related white matter changes using transcranial Doppler ultrasonography. J Neuroimaging 2011 0.88
22 Preliminary findings of the effects of autonomic dysfunction on functional outcome after acute ischemic stroke. Clin Neurol Neurosurg 2011 0.86
23 Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase. FEBS Lett 2011 0.86
24 Selection of aptamers for signal transduction proteins by capillary electrophoresis. Electrophoresis 2010 0.84
25 C1, see them all. Trends Biochem Sci 2005 0.84
26 Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation. Eur J Cell Biol 2002 0.83
27 Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. J Biol Chem 2004 0.81
28 Myosin light chain kinases: division of work in cell migration. Cell Adh Migr 2009 0.80
29 Genomic organization of human myotonic dystrophy kinase-related Cdc42-binding kinase alpha reveals multiple alternative splicing and functional diversity. Gene 2003 0.79
30 Cerebral Microbleeds and Cognitive Function in Ischemic Stroke or Transient Ischemic Attack Patients. Dement Geriatr Cogn Disord 2015 0.77
31 Molecular aptamer beacon for myotonic dystrophy kinase-related Cdc42-binding kinase alpha. Talanta 2010 0.76
32 Rivastigmine in Chinese patients with subcortical vascular dementia. Neuropsychiatr Dis Treat 2007 0.76
33 Comparison of carotid atherosclerotic plaque characteristics between patients with first-time and recurrent acute ischaemic stroke using B-mode ultrasound. Neurol Res 2015 0.75
34 Introduction of dominant inhibitory proteins directed against ROK and MRCK kinases. Methods Mol Biol 2002 0.75
35 Embolic Doppler ultrasound signal detection using continuous wavelet transform to detect multiple vascular emboli. J Neuroimaging 2008 0.75