Published in Nat Genet on October 06, 2013
Ectopic lymphoid-like structures in infection, cancer and autoimmunity. Nat Rev Immunol (2014) 1.72
Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome. Clin Immunol (2016) 1.41
High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry. Nat Genet (2016) 1.09
Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. Am J Hum Genet (2014) 0.99
Genome-wide association studies in Sjögren's syndrome: What do the genes tell us about disease pathogenesis? Autoimmun Rev (2014) 0.96
The contribution of epigenetics in Sjögren's Syndrome. Front Genet (2014) 0.93
Genetics of autoimmune diseases: perspectives from genome-wide association studies. Int Immunol (2016) 0.93
Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes. Ann Rheum Dis (2016) 0.92
The immunogenetics of Behçet's disease: A comprehensive review. J Autoimmun (2015) 0.91
Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. Ann Rheum Dis (2015) 0.89
The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet (2014) 0.88
T cell epitope mimicry between Sjögren's syndrome Antigen A (SSA)/Ro60 and oral, gut, skin and vaginal bacteria. Clin Immunol (2014) 0.88
Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndrome. Ann Rheum Dis (2015) 0.87
The effect of inversion at 8p23 on BLK association with lupus in Caucasian population. PLoS One (2014) 0.86
The relevance of HLA sequencing in population genetics studies. J Immunol Res (2014) 0.86
Shared signatures between rheumatoid arthritis, systemic lupus erythematosus and Sjögren's syndrome uncovered through gene expression meta-analysis. Arthritis Res Ther (2014) 0.84
X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome. Arthritis Rheumatol (2016) 0.84
An in silico Approach Reveals Associations between Genetic and Epigenetic Factors within Regulatory Elements in B Cells from Primary Sjögren's Syndrome Patients. Front Immunol (2015) 0.83
Epigenetic Signatures of Salivary Gland Inflammation in Sjögren's Syndrome. Arthritis Rheumatol (2016) 0.83
High-accuracy imputation for HLA class I and II genes based on high-resolution SNP data of population-specific references. Pharmacogenomics J (2015) 0.83
Interleukin-6 deficiency corrects nephritis, lymphocyte abnormalities, and secondary Sjögren's syndrome features in lupus-prone Sle1.Yaa mice. Arthritis Rheumatol (2014) 0.82
Familial Risk of Sjögren's Syndrome and Co-aggregation of Autoimmune Diseases in Affected Families: A Nationwide Population Study. Arthritis Rheumatol (2015) 0.82
A pathogenetic role for IL-21 in primary Sjögren syndrome. Nat Rev Rheumatol (2015) 0.81
Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren's syndrome. Arthritis Res Ther (2014) 0.81
Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren's Syndrome According to Ancestry. Arthritis Rheumatol (2017) 0.81
Complicating autoimmune diseases in myasthenia gravis: a review. Autoimmunity (2015) 0.80
A genome-wide association study of marginal zone lymphoma shows association to the HLA region. Nat Commun (2015) 0.80
Clinical Characteristics and Outcome of Primary Sjogren's Syndrome: A Large Asian Indian Cohort. Open Rheumatol J (2015) 0.79
Genetic architectures of seropositive and seronegative rheumatic diseases. Nat Rev Rheumatol (2015) 0.79
Concordance of increased B1 cell subset and lupus phenotypes in mice and humans is dependent on BLK expression levels. J Immunol (2015) 0.79
Human FcR polymorphism and disease. Curr Top Microbiol Immunol (2014) 0.79
Contribution of Genetic Factors to Sjögren's Syndrome and Sjögren's Syndrome Related Lymphomagenesis. J Immunol Res (2015) 0.78
Single-cell analysis of glandular T cell receptors in Sjögren's syndrome. JCI Insight (2016) 0.78
Suppression of IRAK1 or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding-Defective Mutant of ABIN1. J Immunol (2016) 0.77
Candidate chromosome 1 disease susceptibility genes for Sjogren's syndrome xerostomia are narrowed by novel NOD.B10 congenic mice. Clin Immunol (2014) 0.76
The clinical relevance of animal models in Sjögren's syndrome: the interferon signature from mouse to man. Arthritis Res Ther (2015) 0.76
Mouse Models of Primary Sjogren's Syndrome. Curr Pharm Des (2015) 0.76
Epidemiology of Sjögren's Syndrome-from an Oral Perspective. Curr Oral Health Rep (2016) 0.76
Advances in systems biology approaches for autoimmune diseases. Immune Netw (2014) 0.75
Dry eye management in a Sjögren's syndrome mouse model by inhibition of p38-MAPK pathway. Diagn Pathol (2014) 0.75
Genetic Susceptibility to ANCA-Associated Vasculitis: State of the Art. Front Immunol (2014) 0.75
Association-heterogeneity mapping identifies an Asian-specific association of the GTF2I locus with rheumatoid arthritis. Sci Rep (2016) 0.75
The expression of B & T cell activation markers in children's tonsils following live attenuated influenza vaccine. Hum Vaccin Immunother (2015) 0.75
Association of IL12A Expression Quantitative Trait Loci (eQTL) With Primary Biliary Cirrhosis in a Chinese Han Population. Medicine (Baltimore) (2016) 0.75
Pharmacogenetics and interstitial lung disease. Curr Opin Pulm Med (2016) 0.75
Glutathione protects against hepatic injury in a murine model of primary Sjögren's syndrome. Bosn J Basic Med Sci (2016) 0.75
A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases. Nat Genet (2017) 0.75
Reduction of T cell receptor diversity in NOD mice prevents development of type 1 diabetes but not Sjögren's syndrome. PLoS One (2014) 0.75
Effect of Tobacco Smoking on The Clinical, Histopathological, and Serological Manifestations of Sjögren's Syndrome. PLoS One (2017) 0.75
Possible single-nucleotide polymorphism loci associated with systemic sclerosis susceptibility: a genetic association study in a Chinese Han population. PLoS One (2014) 0.75
Recent advances in primary Sjogren's syndrome. F1000Res (2016) 0.75
Update on Pathogenesis of Sjögren's syndrome. Curr Rheumatol Rev (2016) 0.75
Single nucleotide polymorphisms in the FAM167A-BLK gene are associated with polymyositis/dermatomyositis in the Han Chinese population. Immunol Res (2015) 0.75
Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren's Syndrome. Invest Ophthalmol Vis Sci (2017) 0.75
B cells gone rogue: the intersection of diffuse large B cell lymphoma and autoimmune disease. Expert Rev Hematol (2016) 0.75
Network-assisted analysis of primary Sjögren's syndrome GWAS data in Han Chinese. Sci Rep (2015) 0.75
Connective tissue diseases: Sjögren syndrome genetics vary according to ancestry. Nat Rev Rheumatol (2017) 0.75
Sex differential association of dermatomyositis with Sjögren syndrome. CMAJ (2017) 0.75
A critical role for IRF5 in regulating allergic airway inflammation. Mucosal Immunol (2016) 0.75
Incidence and Mortality of Physician-Diagnosed Primary Sjögren Syndrome: Time Trends Over a 40-Year Period in a Population-Based US Cohort. Mayo Clin Proc (2017) 0.75
Multiple signals at the extended 8p23 locus are associated with susceptibility to systemic lupus erythematosus. J Med Genet (2017) 0.75
Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genet (2017) 0.75
Effects of Type 1 Diabetes Risk Alleles on Immune Cell Gene Expression. Genes (Basel) (2017) 0.75
Common variants near IKZF1 are associated with primary Sjögren's syndrome in Han Chinese. PLoS One (2017) 0.75
Biosemantics guided gene expression profiling of Sjögren's syndrome: a comparative analysis with systemic lupus erythematosus and rheumatoid arthritis. Arthritis Res Ther (2017) 0.75
First Association of Interleukin 12 Receptor Beta 1 Deficiency with Sjögren's Syndrome. Front Immunol (2017) 0.75
[Sjögren's syndrome]. Z Rheumatol (2014) 0.75
Long-term follow-up in primary Sjögren's syndrome reveals differences in clinical presentation between female and male patients. Biol Sex Differ (2017) 0.75
Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity. Clin Rev Allergy Immunol (2017) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Measuring inconsistency in meta-analyses. BMJ (2003) 128.20
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics (2010) 53.23
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet (2009) 30.09
Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics (2006) 22.61
METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics (2010) 21.21
Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis (2002) 20.48
A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol (2011) 16.53
The UCSC Genome Browser database: update 2011. Nucleic Acids Res (2010) 16.24
LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics (2010) 13.54
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. Arthritis Rheum (2008) 13.08
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet (2008) 12.51
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet (2010) 9.90
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med (2007) 9.80
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med (2008) 9.61
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet (2009) 9.45
Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet (2008) 7.63
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet (2011) 6.20
Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations. Ann Hum Genet (2000) 6.13
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet (2009) 5.75
Promise and pitfalls of the Immunochip. Arthritis Res Ther (2011) 5.38
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature (2005) 5.37
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat Genet (2012) 5.11
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet (2005) 4.80
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A (2007) 4.71
Matrix eQTL: ultra fast eQTL analysis via large matrix operations. Bioinformatics (2012) 4.28
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N Engl J Med (2009) 3.70
Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12. Immunol Cell Biol (2009) 3.51
A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data. Nucleic Acids Res (2009) 3.50
Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4. Immunol Rev (2004) 3.18
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. Nat Genet (2010) 3.15
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. Proc Natl Acad Sci U S A (2006) 3.11
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Nat Genet (2011) 3.06
A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: utility and applications. Hum Mutat (2008) 2.96
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet (2010) 2.61
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet (2011) 2.54
The 1000 Genomes Project: new opportunities for research and social challenges. Genome Med (2010) 2.43
Gene expression profiling of minor salivary glands clearly distinguishes primary Sjögren's syndrome patients from healthy control subjects. Arthritis Rheum (2005) 2.21
An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases. Hum Mol Genet (2007) 2.14
Revising B cell receptors. J Exp Med (2000) 1.96
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus. Hum Mol Genet (2007) 1.95
Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis. Arthritis Rheum (2009) 1.88
Regulation of immunity and oncogenesis by the IRF transcription factor family. Cancer Immunol Immunother (2010) 1.79
Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genet (2011) 1.77
STAT4: a critical regulator of inflammation in vivo. Immunol Res (2005) 1.77
The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype. Hum Mol Genet (2009) 1.73
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis. Arthritis Rheum (2007) 1.72
Peripheral blood gene expression profiling in Sjögren's syndrome. Genes Immun (2009) 1.66
HIBAG--HLA genotype imputation with attribute bagging. Pharmacogenomics J (2013) 1.66
Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations. J Med Genet (2008) 1.59
Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27. Clin Dev Immunol (2010) 1.59
Incidence of physician-diagnosed primary Sjögren syndrome in residents of Olmsted County, Minnesota. Mayo Clin Proc (2001) 1.47
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet (2012) 1.41
Association of an IRF5 gene functional polymorphism with Sjögren's syndrome. Arthritis Rheum (2007) 1.40
The complexity of Sjögren's syndrome: novel aspects on pathogenesis. Immunol Lett (2011) 1.35
Variant form of STAT4 is associated with primary Sjögren's syndrome. Genes Immun (2008) 1.31
NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression. J Immunol (2012) 1.29
Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome. Genes Immun (2010) 1.21
B cells in Sjögren's syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissue. Arthritis Res Ther (2007) 1.16
LitInspector: literature and signal transduction pathway mining in PubMed abstracts. Nucleic Acids Res (2009) 1.14
Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome. Genes Immun (2008) 1.13
HLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies. Autoimmun Rev (2011) 1.12
The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome. Arthritis Rheum (2009) 1.05
Genetics of Sjögren's syndrome in the genome-wide association era. J Autoimmun (2012) 1.01
Genes and Sjögren's syndrome. Rheum Dis Clin North Am (2008) 1.01
Incidence of primary Sjogren's syndrome in Slovenia. Ann Rheum Dis (2004) 0.98
GenomeRunner: automating genome exploration. Bioinformatics (2011) 0.97
The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development. Hum Mol Genet (2012) 0.97
Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus. Arthritis Rheum (2012) 0.96
Gene expression and chromosomal location for susceptibility to Sjögren's syndrome. J Autoimmun (2009) 0.94
The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype. Ann Rheum Dis (2010) 0.92
STAT4 is a confirmed genetic risk factor for Sjögren's syndrome and could be involved in type 1 interferon pathway signaling. Genes Immun (2010) 0.91
Comparison of HLA class II genes in Caucasoid, Chinese, and Japanese patients with primary Sjögren's syndrome. J Immunol (1993) 0.91
Primary Sjogren's syndrome: current and prospective therapies. Semin Arthritis Rheum (2007) 0.87
HLA class I and class II are both associated with the genetic predisposition to primary Sjögren syndrome. Hum Immunol (2001) 0.87
Autosome-wide copy number variation association analysis for rheumatoid arthritis using the WTCCC high-density SNP genotype data. J Rheumatol (2011) 0.83
Mutation in a winged-helix DNA-binding motif causes atypical bare lymphocyte syndrome. Nat Immunol (2002) 0.81
B cell antigen receptor signalling in the balance of tolerance and immunity. Novartis Found Symp (1998) 0.81
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet (2008) 12.51
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci U S A (2003) 11.65
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature (2007) 10.98
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis (2013) 10.92
Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med (2003) 10.82
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med (2008) 9.61
Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature (2006) 9.30
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Regression of splenic lymphoma with villous lymphocytes after treatment of hepatitis C virus infection. N Engl J Med (2002) 7.52
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet (2008) 6.42
FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity. Nat Genet (2007) 5.93
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet (2009) 5.75
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Brain environment interactions: stress, posttraumatic stress disorder, and the need for a postmortem brain collection. Psychiatry (2004) 5.29
Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Nat Genet (2008) 5.00
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet (2005) 4.80
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat Genet (2007) 4.76
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A (2007) 4.71
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet (2004) 4.46
The EUROclass trial: defining subgroups in common variable immunodeficiency. Blood (2007) 4.14
Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Hum Mol Genet (2007) 4.09
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet (2002) 4.03
International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies. Ann Rheum Dis (2013) 3.99
Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility. Nat Genet (2005) 3.86
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res (2009) 3.81
Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum (2010) 3.76
A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. Nat Genet (2008) 3.71
Bacteremia associated with toothbrushing and dental extraction. Circulation (2008) 3.71
Identification and characterization of circulating human transitional B cells. Blood (2005) 3.62
Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum (2004) 3.57
Defining the role of the MHC in autoimmunity: a review and pooled analysis. PLoS Genet (2008) 3.54
Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J Clin Oncol (2009) 3.37
CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms. Nat Immunol (2007) 3.31
Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med (2010) 3.24
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet (2005) 3.15
The majority of microRNAs detectable in serum and saliva is concentrated in exosomes. PLoS One (2012) 3.14
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. Proc Natl Acad Sci U S A (2006) 3.11
Neurobehavioral derangements in adult mice receiving decabrominated diphenyl ether (PBDE 209) during a defined period of neonatal brain development. Toxicol Sci (2003) 2.99
Immune activation in patients with irritable bowel syndrome. Gastroenterology (2007) 2.82
Subjective improvement in patients with psoriatic arthritis after short-term oral treatment with seal oil. A pilot study with double blind comparison to soy oil. J Rheumatol (2006) 2.80
Safety and efficacy of rituximab in systemic lupus erythematosus: results from 136 patients from the French AutoImmunity and Rituximab registry. Arthritis Rheum (2010) 2.68
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α. Nat Med (2012) 2.66
Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients. Arthritis Rheum (2008) 2.62
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet (2010) 2.61
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet (2013) 2.60
Protein kinase cδ deficiency causes mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation. Arthritis Rheum (2013) 2.60
Signs of first-degree heart block occur in one-third of fetuses of pregnant women with anti-SSA/Ro 52-kd antibodies. Arthritis Rheum (2004) 2.58
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet (2011) 2.54
Symptomatic efficacy of etanercept and its effects on objective signs of inflammation in early nonradiographic axial spondyloarthritis: a multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheumatol (2014) 2.52
Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells. J Bone Miner Res (2002) 2.48
Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies. Nat Rev Genet (2009) 2.46
Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG. J Immunol (2003) 2.45
A systematic review of dental disease in patients undergoing cancer therapy. Support Care Cancer (2010) 2.43
Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanism. Arthritis Rheum (2005) 2.42
Bicuspid aortic valve leaflet morphology in relation to aortic root morphology: a study of 300 patients undergoing open-heart surgery. Eur J Cardiothorac Surg (2011) 2.41
Maintenance of infliximab treatment in ankylosing spondylitis: results of a one-year randomized controlled trial comparing systematic versus on-demand treatment. Arthritis Rheum (2008) 2.41
Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Nat Genet (2007) 2.38
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen. Cancer Cell (2005) 2.37