Published in Annu Rev Physiol on October 16, 2013
Strategies to increase nitric oxide signalling in cardiovascular disease. Nat Rev Drug Discov (2015) 1.18
On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry. J Am Chem Soc (2016) 0.86
Omega-3 and -6 fatty acids allocate somatic and germline lipids to ensure fitness during nutrient and oxidative stress in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2015) 0.82
Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride. Nat Chem Biol (2015) 0.81
Bioorthogonal Chemical Reporters for Monitoring Unsaturated Fatty-Acylated Proteins. Chembiochem (2016) 0.79
The science of fatty acids and inflammation. Adv Nutr (2015) 0.79
15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways. Chem Biol Interact (2014) 0.77
T-REX on-demand redox targeting in live cells. Nat Protoc (2016) 0.77
Saturated fatty acids enhance TLR4 immune pathways in human trophoblasts. Hum Reprod (2015) 0.77
Nitro-fatty acids in cardiovascular regulation and diseases: characteristics and molecular mechanisms. Front Biosci (Landmark Ed) (2016) 0.76
Electrophilic nitro-fatty acids suppress allergic contact dermatitis in mice. Allergy (2016) 0.76
Evaluation of 10-Nitro Oleic Acid Bio-Elimination in Rats and Humans. Sci Rep (2017) 0.76
The Chemical Basis of Thiol Addition to Nitro-Conjugated Linoleic Acid, a Protective Cell-Signaling Lipid. J Biol Chem (2016) 0.75
Activation of TRPC channels contributes to OA-NO2-induced responses in guinea-pig dorsal root ganglion neurons. J Physiol (2014) 0.75
Enterosalivary nitrate metabolism and the microbiome: intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health. Free Radic Biol Med (2016) 0.75
Nitro-fatty acids in plant signaling: New key mediators of nitric oxide metabolism. Redox Biol (2017) 0.75
Nitro-oleic acid and epoxyoleic acid are not altered in obesity and type 2 diabetes: reply. Cardiovasc Res (2014) 0.75
Nitro-oleic acid regulates growth factor-induced differentiation of bone marrow-derived macrophages. Free Radic Biol Med (2017) 0.75
Privileged Electrophile Sensors: A Resource for Covalent Drug Development. Cell Chem Biol (2017) 0.75
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol (2007) 12.48
NF-kappaB: a key role in inflammatory diseases. J Clin Invest (2001) 9.66
Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem (2008) 9.56
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell (1995) 7.99
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature (2007) 7.12
Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol (2004) 6.83
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature (2000) 4.66
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med (2005) 4.31
The JAK/STAT signaling pathway. J Cell Sci (2004) 4.23
Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. Proc Natl Acad Sci U S A (1974) 4.10
The resurgence of covalent drugs. Nat Rev Drug Discov (2011) 4.09
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol Cell Biol (2006) 3.97
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. Biochem J (2004) 3.15
Resolvins and protectins in inflammation resolution. Chem Rev (2011) 3.09
Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligand. Proc Natl Acad Sci U S A (2005) 3.03
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4). Nat Med (2002) 2.94
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway. Nat Immunol (2004) 2.86
Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins. FASEB J (2009) 2.83
Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands. J Biol Chem (2005) 2.79
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol Cell Biol (2008) 2.57
Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators. J Biol Chem (2006) 2.31
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2). Mol Cell Biol (2004) 2.25
Structural basis for the activation of PPARgamma by oxidized fatty acids. Nat Struct Mol Biol (2008) 2.25
Free radical lipid peroxidation: mechanisms and analysis. Chem Rev (2011) 2.17
Free radicals, mitochondria, and oxidized lipids: the emerging role in signal transduction in vascular cells. Circ Res (2006) 2.14
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. J Immunol (2007) 2.11
Cyclopentenone prostaglandins: new insights on biological activities and cellular targets. Med Res Rev (2001) 2.09
Generation and biological activities of oxidized phospholipids. Antioxid Redox Signal (2010) 2.04
15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. J Biol Chem (2002) 2.04
Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annu Rev Pharmacol Toxicol (2012) 2.01
Red cell membrane and plasma linoleic acid nitration products: synthesis, clinical identification, and quantitation. Proc Natl Acad Sci U S A (2004) 1.98
Reversible post-translational modification of proteins by nitrated fatty acids in vivo. J Biol Chem (2006) 1.96
Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury. Am J Respir Crit Care Med (2005) 1.94
Novel proresolving aspirin-triggered DHA pathway. Chem Biol (2011) 1.93
Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids. J Biol Chem (2010) 1.83
Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol (2008) 1.83
Formation and signaling actions of electrophilic lipids. Chem Rev (2011) 1.82
Epoxides and soluble epoxide hydrolase in cardiovascular physiology. Physiol Rev (2012) 1.82
15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury. Am J Respir Crit Care Med (2009) 1.81
Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. Nat Chem Biol (2010) 1.77
Effects of n-3 fatty acids on macro- and microvascular function in subjects with type 2 diabetes mellitus. Am J Clin Nutr (2010) 1.75
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. FASEB J (2002) 1.73
Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway. Am J Physiol Heart Circ Physiol (2007) 1.70
Molecular recognition of nitrated fatty acids by PPAR gamma. Nat Struct Mol Biol (2008) 1.67
Transduction of redox signaling by electrophile-protein reactions. Sci Signal (2009) 1.62
Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP. J Biol Chem (2001) 1.61
Regulatory action on rosiglitazone by the U.S. Food and Drug Administration. N Engl J Med (2010) 1.59
Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion. Cardiovasc Res (2010) 1.58
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension. Eur Respir J (2008) 1.58
Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid. J Biol Chem (2009) 1.58
Anti-inflammatory properties of omega-3 fatty acids in critical illness: novel mechanisms and an integrative perspective. Intensive Care Med (2008) 1.57
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. J Biol Chem (2005) 1.54
Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3. Chem Res Toxicol (2008) 1.47
Thioredoxin as a molecular target of cyclopentenone prostaglandins. J Biol Chem (2003) 1.45
Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction. Biochem J (2008) 1.44
Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. Am J Clin Nutr (2000) 1.43
Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: implications for cardioprotection. Cardiovasc Res (2008) 1.41
Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid potently activates endothelial heme oxygenase 1 expression. Proc Natl Acad Sci U S A (2006) 1.41
Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages. Mol Cell Biol (2000) 1.39
Reversibility of covalent electrophile-protein adducts and chemical toxicity. Chem Res Toxicol (2008) 1.38
Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. Biochim Biophys Acta (2010) 1.36
Nitro-fatty acid metabolome: saturation, desaturation, beta-oxidation, and protein adduction. J Biol Chem (2008) 1.35
Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells. J Biol Chem (1999) 1.35
Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism. J Biol Chem (2011) 1.34
Nitro-oleic acid inhibits angiotensin II-induced hypertension. Circ Res (2010) 1.34
Nitrooleic acid, an endogenous product of nitrative stress, activates nociceptive sensory nerves via the direct activation of TRPA1. Mol Pharmacol (2009) 1.33
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration. Nat Chem Biol (2012) 1.32
Electrophilic natural products and their biological targets. Nat Prod Rep (2012) 1.32
Metalloproteinases and vulnerable atherosclerotic plaques. Trends Cardiovasc Med (2007) 1.32
Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways. Arterioscler Thromb Vasc Biol (2010) 1.29
15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. J Biol Chem (2003) 1.28
Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid. J Biol Chem (2008) 1.26
Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase. J Biol Chem (2008) 1.26
Conjugated linoleic acid isomers: differences in metabolism and biological effects. Biofactors (2009) 1.24
Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate. Biochem J (2009) 1.24
Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts. J Mol Cell Cardiol (2007) 1.24
Theoretical calculations of carbon-oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids. J Am Chem Soc (2003) 1.23
A lipid peroxidation-derived inflammatory mediator: identification of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages. J Biol Chem (2004) 1.22
Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids. J Mol Biol (2008) 1.21
Nitroalkenes suppress lipopolysaccharide-induced signal transducer and activator of transcription signaling in macrophages: a critical role of mitogen-activated protein kinase phosphatase 1. Endocrinology (2008) 1.16
Molecular mechanisms of the conjugated alpha,beta-unsaturated carbonyl derivatives: relevance to neurotoxicity and neurodegenerative diseases. Toxicol Sci (2007) 1.15
Plant oxylipins: plant responses to 12-oxo-phytodienoic acid are governed by its specific structural and functional properties. FEBS J (2009) 1.15
Nitro-oleic acid protects the mouse kidney from ischemia and reperfusion injury. Am J Physiol Renal Physiol (2008) 1.14
NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation. Mol Pharmacol (2009) 1.14
Modulation of nitrated lipid signaling by multidrug resistance protein 1 (MRP1): glutathione conjugation and MRP1-mediated efflux inhibit nitrolinoleic acid-induced, PPARgamma-dependent transcription activation. Biochemistry (2006) 1.14
Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2. Free Radic Biol Med (2009) 1.13
Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury. Circ Res (2009) 1.13
Site and mechanism of growth inhibition by prostaglandins. II. Temperature-dependent transfer of a cyclopentenone prostaglandin to nuclei. J Pharmacol Exp Ther (1986) 1.11
15-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation. Mol Pharmacol (2009) 1.10
15-Deoxy-Δ¹²,¹⁴-prostaglandin J₂, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling. Biochem Pharmacol (2011) 1.10
Conjugated linoleic acid is a preferential substrate for fatty acid nitration. J Biol Chem (2012) 1.09
An overview of the chemistry and biology of reactive aldehydes. Free Radic Biol Med (2012) 1.08
Nitro-oleic acid protects against endotoxin-induced endotoxemia and multiorgan injury in mice. Am J Physiol Renal Physiol (2009) 1.08
The autoxidation of arachidonic acid: formation of the proposed SRS-A intermediate. Biochem Biophys Res Commun (1979) 1.08
Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2010) 1.08
Activation of vascular endothelial nitric oxide synthase and heme oxygenase-1 expression by electrophilic nitro-fatty acids. Free Radic Biol Med (2009) 1.06
Synthesis, isomer characterization, and anti-inflammatory properties of nitroarachidonate. Biochemistry (2007) 1.05
Nitrated oleic acid up-regulates PPARgamma and attenuates experimental inflammatory bowel disease. Free Radic Biol Med (2009) 1.04
Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science (2002) 3.13
Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligand. Proc Natl Acad Sci U S A (2005) 3.03
The emerging biology of the nitrite anion. Nat Chem Biol (2005) 2.88
Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands. J Biol Chem (2005) 2.79
Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators. J Biol Chem (2006) 2.31
Nitrate and nitrite in biology, nutrition and therapeutics. Nat Chem Biol (2009) 2.29
Red cell membrane and plasma linoleic acid nitration products: synthesis, clinical identification, and quantitation. Proc Natl Acad Sci U S A (2004) 1.98
Reversible post-translational modification of proteins by nitrated fatty acids in vivo. J Biol Chem (2006) 1.96
NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response? Trends Biochem Sci (2003) 1.90
Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins. Proc Natl Acad Sci U S A (2004) 1.87
Formation and signaling actions of electrophilic lipids. Chem Rev (2011) 1.82
Hypercapnia via reduced rate and tidal volume contributes to lipopolysaccharide-induced lung injury. Am J Respir Crit Care Med (2004) 1.81
Nitro-fatty acid reaction with glutathione and cysteine. Kinetic analysis of thiol alkylation by a Michael addition reaction. J Biol Chem (2007) 1.78
Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. Nat Chem Biol (2010) 1.77
Fatty acid transduction of nitric oxide signaling. Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor. J Biol Chem (2005) 1.75
Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway. Am J Physiol Heart Circ Physiol (2007) 1.70
Molecular recognition of nitrated fatty acids by PPAR gamma. Nat Struct Mol Biol (2008) 1.67
Fatty acid nitroalkenes ameliorate glucose intolerance and pulmonary hypertension in high-fat diet-induced obesity. Cardiovasc Res (2014) 1.65
Transduction of redox signaling by electrophile-protein reactions. Sci Signal (2009) 1.62
Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP. J Biol Chem (2001) 1.61
Nitric oxide's reactions with hemoglobin: a view through the SNO-storm. Nat Med (2003) 1.61
Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival. J Clin Invest (2011) 1.60
Nitrolinoleate, a nitric oxide-derived mediator of cell function: synthesis, characterization, and vasomotor activity. Proc Natl Acad Sci U S A (2002) 1.59
Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion. Cardiovasc Res (2010) 1.58
Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid. J Biol Chem (2009) 1.58
Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions. J Biol Chem (2010) 1.57
Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. Free Radic Biol Med (2011) 1.56
Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species. Chem Res Toxicol (2012) 1.51
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. Nat Med (2010) 1.49
Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite. Biochemistry (2003) 1.46
Nitric oxide-dependent generation of reactive species in sickle cell disease. Actin tyrosine induces defective cytoskeletal polymerization. J Biol Chem (2002) 1.42
Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid potently activates endothelial heme oxygenase 1 expression. Proc Natl Acad Sci U S A (2006) 1.41
Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: implications for cardioprotection. Cardiovasc Res (2008) 1.41
Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases. Free Radic Biol Med (2002) 1.40
Reactivity of sulfenic acid in human serum albumin. Biochemistry (2007) 1.37
Nitro-fatty acid metabolome: saturation, desaturation, beta-oxidation, and protein adduction. J Biol Chem (2008) 1.35
Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism. J Biol Chem (2011) 1.34
Nitro-oleic acid inhibits angiotensin II-induced hypertension. Circ Res (2010) 1.34
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration. Nat Chem Biol (2012) 1.32
Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase. J Biol Chem (2008) 1.26
Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate. Biochem J (2009) 1.24
Hydrogen peroxide is the major oxidant product of xanthine oxidase. Free Radic Biol Med (2009) 1.23
Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis. Arthritis Rheum (2006) 1.20
Nitroalkenes suppress lipopolysaccharide-induced signal transducer and activator of transcription signaling in macrophages: a critical role of mitogen-activated protein kinase phosphatase 1. Endocrinology (2008) 1.16
Myeloperoxidase enhances nitric oxide catabolism during myocardial ischemia and reperfusion. Free Radic Biol Med (2004) 1.16
Oxypurinol improves coronary and peripheral endothelial function in patients with coronary artery disease. Free Radic Biol Med (2005) 1.15
Inactivation of human Cu,Zn superoxide dismutase by peroxynitrite and formation of histidinyl radical. Free Radic Biol Med (2004) 1.13
Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury. Circ Res (2009) 1.13
Redox signaling in inflammation: interactions of endogenous electrophiles and mitochondria in cardiovascular disease. Ann N Y Acad Sci (2010) 1.11
Febuxostat inhibition of endothelial-bound XO: implications for targeting vascular ROS production. Free Radic Biol Med (2011) 1.09
Binding of xanthine oxidase to glycosaminoglycans limits inhibition by oxypurinol. J Biol Chem (2004) 1.09
Conjugated linoleic acid is a preferential substrate for fatty acid nitration. J Biol Chem (2012) 1.09
Convergence of nitric oxide and lipid signaling: anti-inflammatory nitro-fatty acids. Free Radic Biol Med (2008) 1.09
Cytochrome c: a catalyst and target of nitrite-hydrogen peroxide-dependent protein nitration. Arch Biochem Biophys (2004) 1.08
Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2010) 1.08
Activation of vascular endothelial nitric oxide synthase and heme oxygenase-1 expression by electrophilic nitro-fatty acids. Free Radic Biol Med (2009) 1.06
Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine. J Lipid Res (2013) 1.06
Nitrated oleic acid up-regulates PPARgamma and attenuates experimental inflammatory bowel disease. Free Radic Biol Med (2009) 1.04
PPARgamma and its ligands: therapeutic implications in cardiovascular disease. Clin Sci (Lond) (2009) 1.03
Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. Genes Cells (2010) 1.03
Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts. Cardiovasc Res (2013) 1.01
Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice. Cancer Res (2005) 1.00
Cardiovascular consequences when nitric oxide and lipid signaling converge. Circ Res (2009) 0.98
Albumin and hydroxyethyl starch modulate oxidative inflammatory injury to vascular endothelium. Anesthesiology (2004) 0.98
Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions. Biochem J (2009) 0.95
Electrophilic fatty acids regulate matrix metalloproteinase activity and expression. J Biol Chem (2011) 0.95
Obesity-induced tissue free radical generation: an in vivo immuno-spin trapping study. Free Radic Biol Med (2012) 0.93
Redox-dependent impairment of vascular function in sickle cell disease. Free Radic Biol Med (2007) 0.93
Diffusion of nitric oxide into low density lipoprotein. J Biol Chem (2001) 0.93
Signaling actions of electrophiles: anti-inflammatory therapeutic candidates. Mol Interv (2010) 0.93
Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis. J Neurosci (2013) 0.92
Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ. J Biol Chem (2012) 0.92
Peroxynitrite-mediated alpha-tocopherol oxidation in low-density lipoprotein: a mechanistic approach. Free Radic Biol Med (2004) 0.91
Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment. Curr Opin Pharmacol (2010) 0.91
New insights into the role of fatty acids in the pathogenesis and resolution of inflammatory bowel disease. Inflamm Bowel Dis (2010) 0.89
Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. J Biol Chem (2013) 0.89
A retrospective mathematical analysis of controlled release design and experimentation. Mol Pharm (2012) 0.88
Protective effects of 10-nitro-oleic acid in a hypoxia-induced murine model of pulmonary hypertension. Am J Respir Cell Mol Biol (2014) 0.88
Gas-phase fragmentation analysis of nitro-fatty acids. J Am Soc Mass Spectrom (2011) 0.86
Promotion of cardiovascular disease by exposure to the air pollutant ozone. Am J Physiol Lung Cell Mol Physiol (2009) 0.86
Atypical PKCζ transduces electrophilic fatty acid signaling in pulmonary epithelial cells. Nitric Oxide (2011) 0.83
Inhibition of xanthine oxidase improves myocardial contractility in patients with ischemic cardiomyopathy. Free Radic Biol Med (2006) 0.82
Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid mediates protective effects through regulation of the ERK pathway. Free Radic Biol Med (2008) 0.81
Oxidases and oxygenases in regulation of vascular nitric oxide signaling and inflammatory responses. Immunol Res (2002) 0.80
L-Arginine inhibits xanthine oxidase-dependent endothelial dysfunction in hypercholesterolemia. FEBS Lett (2004) 0.80
Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S center. Free Radic Biol Med (2013) 0.79
Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase. J Pharmacol Exp Ther (2008) 0.77
Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation. Antioxid Redox Signal (2014) 0.77
Biomimetic nitration of conjugated linoleic acid: formation and characterization of naturally occurring conjugated nitrodienes. J Org Chem (2013) 0.77
Do we kNOw how HSP90 and eNOS mediate lung injury in sickle cell disease? Am J Physiol Lung Cell Mol Physiol (2004) 0.75
Blood pressure regulation: role for neutrophils? Blood (2008) 0.75
Copper trafficking and extracellular superoxide dismutase activity: kinky hair, kinky vessels. Hypertension (2008) 0.75
A new hammer in the redox toolbox: high-purity peroxynitrite for cell signaling and toxicology studies. Chem Res Toxicol (2008) 0.75