Published in J Immunol on January 01, 1986
Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain. J Exp Med (1986) 2.55
Cell surface expression and metabolism of major histocompatibility complex class II invariant chain (CD74) by diverse cell lines. Immunology (1999) 1.08
Internalization and catabolism of radiolabelled antibodies to the MHC class-II invariant chain by B-cell lymphomas. Biochem J (1996) 1.04
The development of potential antibody-based therapies for myeloma. Blood Rev (2014) 0.81
Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum. EMBO J (1990) 7.03
Molecular cloning of the a1 locus of Zea mays using the transposable elements En and Mu1. EMBO J (1985) 6.97
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem (1994) 6.18
The regulatory c1 locus of Zea mays encodes a protein with homology to myb proto-oncogene products and with structural similarities to transcriptional activators. EMBO J (1987) 5.98
An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science (1996) 5.93
Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science (1992) 4.74
PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr Biol (1995) 4.52
Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum. Cell (1989) 4.47
The Spm (En) transposable element controls the excision of a 2-kb DNA insert at the wx allele of Zea mays. EMBO J (1984) 4.41
Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove. Science (1997) 4.27
A viral inhibitor of peptide transporters for antigen presentation. Nature (1995) 4.26
Influence of transposable elements on the structure and function of the A1 gene of Zea mays. EMBO J (1987) 4.23
Plant transposable elements generate the DNA sequence diversity needed in evolution. EMBO J (1985) 4.12
Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J (1997) 4.07
2 -Microglobulin--a free immunoglobulin domain. Proc Natl Acad Sci U S A (1972) 3.74
Vascular endothelial growth factor C induces angiogenesis in vivo. Proc Natl Acad Sci U S A (1998) 3.72
Retrieval of transmembrane proteins to the endoplasmic reticulum. J Cell Biol (1993) 3.67
Activation of p70/p85 S6 kinase by a pathway independent of p21ras. Nature (1994) 3.67
Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science (1998) 3.64
Emerging principles for the recognition of peptide antigens by MHC class I molecules. Science (1992) 3.64
Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance. Cell (1985) 3.59
Epidermal Langerhans cells express Ia antigens. Nature (1977) 3.51
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr Biol (1994) 3.44
FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. Trends Pharmacol Sci (2001) 3.42
Atopy in children of families with an anthroposophic lifestyle. Lancet (1999) 3.41
Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens. Cell (1982) 3.36
Intracellular transport of class II MHC molecules directed by invariant chain. Nature (1990) 3.35
Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens. Proc Natl Acad Sci U S A (1982) 3.30
Genetic and molecular analysis of the Enhancer (En) transposable element system of Zea mays. EMBO J (1985) 3.28
FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J (1991) 3.19
Molecular cloning of the c locus of Zea mays: a locus regulating the anthocyanin pathway. EMBO J (1986) 3.18
Human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proc Natl Acad Sci U S A (1996) 3.16
Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res (1992) 3.15
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes. Nature (1996) 3.08
beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J Biol Chem (2000) 2.96
The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP. Immunity (1997) 2.93
Use of anti-idiotypic antibodies as cell-surface receptor probes. Proc Natl Acad Sci U S A (1978) 2.92
A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum. Cell (1987) 2.88
The three-dimensional structure of retinol-binding protein. EMBO J (1984) 2.82
DNA microarrays of the complex human cytomegalovirus genome: profiling kinetic class with drug sensitivity of viral gene expression. J Virol (1999) 2.80
VEGF receptor signal transduction. Sci STKE (2001) 2.75
TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. Science (1999) 2.70
Highly purified papain-solubilized HL-A antigens contain beta2-microglobulin. Proc Natl Acad Sci U S A (1974) 2.66
cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure. Proc Natl Acad Sci U S A (1983) 2.66
An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum. EMBO J (1994) 2.65
Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. EMBO J (1996) 2.64
Regulation of angiogenesis via vascular endothelial growth factor receptors. Cancer Res (2000) 2.63
The complete amino acid sequence of beta 2-microglobulin. Biochemistry (1973) 2.55
Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma. EMBO J (1992) 2.47
Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases. EMBO J (1993) 2.46
TGF-beta 1 binding protein: a component of the large latent complex of TGF-beta 1 with multiple repeat sequences. Cell (1990) 2.46
Structure of the murine immune response I-A beta locus: sequence of the I-A beta gene and an adjacent beta-chain second domain exon. Cell (1983) 2.42
Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity (1994) 2.39
Peptide binding and presentation by mouse CD1. Science (1995) 2.38
Mutations and selection in the generation of class II histocompatibility antigen polymorphism. EMBO J (1984) 2.34
The molecular chaperone calnexin binds Glc1Man9GlcNAc2 oligosaccharide as an initial step in recognizing unfolded glycoproteins. J Biol Chem (1995) 2.31
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines. Cancer Res (1988) 2.28
Four secretory proteins synthesized by hepatocytes are transported from endoplasmic reticulum to Golgi complex at different rates. EMBO J (1984) 2.27
Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase. Oncogene (1994) 2.27
Early BCG vaccination and development of atopy. Lancet (1997) 2.23
Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains. EMBO J (1984) 2.18
Maize transposable elements. Annu Rev Genet (1989) 2.14
Alpha chain of HLA-DR transplantation antigens is a member of the same protein superfamily as the immunoglobulins. Cell (1982) 2.13
Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways. Nature (1990) 2.11
High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proc Natl Acad Sci U S A (1994) 2.09
Antigen presentation and T cell development in H2-M-deficient mice. Science (1996) 2.07
Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease. Histopathology (2001) 2.07
The cell attachment domain of fibronectin. Determination of the primary structure. J Biol Chem (1982) 2.03
The En/Spm transposable element of Zea mays contains splice sites at the termini generating a novel intron from a dSpm element in the A2 gene. EMBO J (1990) 2.00
Evidence in support of a self-perpetuating HLA-DR-dependent delayed-type cell reaction in rheumatoid arthritis. Proc Natl Acad Sci U S A (1982) 1.99
HLA-D region beta-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals. Nature (1983) 1.99
Differentiation of glomerular, tubular, and normal proteinuria: determinations of urinary excretion of beta-2-macroglobulin, albumin, and total protein. J Clin Invest (1969) 1.97
Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Eur Respir J (2003) 1.97
Role of beta2-microglobulin in the intracellular processing of HLA antigens. Biochemistry (1981) 1.96
Molecular association between transplantation antigens and cell surface antigen in adenovirus-transformed cell line. Proc Natl Acad Sci U S A (1978) 1.94
Oligomerization of herpes simplex virus glycoprotein B. J Virol (1986) 1.91
CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation. J Exp Med (1993) 1.91
Structure of C-terminal half of two H-2 antigens from cloned mRNA. Nature (1981) 1.90
Hormonal regulation of the expression of Ia antigens on mammary gland epithelium. Eur J Immunol (1980) 1.90
cDNA clone coding for part of a mouse H-2d major histocompatibility antigen. Proc Natl Acad Sci U S A (1981) 1.90
T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells. J Exp Med (2000) 1.88
Exon-intron organization and complete nucleotide sequence of a human major histocompatibility antigen DC beta gene. Proc Natl Acad Sci U S A (1983) 1.85
PDGF alpha- and beta-receptors activate unique and common signal transduction pathways. EMBO J (1992) 1.85
Regulation of MHC class I transport by the molecular chaperone, calnexin (p88, IP90). Science (1994) 1.79
Empty and peptide-containing conformers of class I major histocompatibility complex molecules expressed in Drosophila melanogaster cells. Proc Natl Acad Sci U S A (1992) 1.79
A role for acidic residues in di-leucine motif-based targeting to the endocytic pathway. J Biol Chem (1995) 1.78
Association of Campylobacter pylori with induced expression of class II transplantation antigens on gastric epithelial cells. Infect Immun (1989) 1.77
Occurrence of Ia antigens on tissues on non-lymphoid origin. Nature (1978) 1.76
Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production. J Exp Med (1998) 1.75
The complete nucleotide sequence of the I-E alpha d immune response gene. Nucleic Acids Res (1983) 1.75
Isolation and identification of a cDNA clone corresponding to an HLA-DR antigen beta chain. Proc Natl Acad Sci U S A (1982) 1.75
Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator. J Exp Med (1994) 1.73
Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors. Oncogene (1994) 1.73
Proteasomes are regulated by interferon gamma: implications for antigen processing. Proc Natl Acad Sci U S A (1992) 1.73
In situ identification of T lymphocyte subsets and HLA-DR expressing cells in the human skin tuberculin reaction. Clin Exp Immunol (1982) 1.71
Radioimmunoassay of 2 -microglobulin in human biological fluids. Scand J Clin Lab Invest (1971) 1.71
Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells. J Exp Med (1997) 1.70
Class II MHC antigen expression in the atherosclerotic plaque: smooth muscle cells express HLA-DR, HLA-DQ and the invariant gamma chain. Clin Exp Immunol (1986) 1.70