ESCRT regulates surface expression of the Kir2.1 potassium channel.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 3890348)

Published in Mol Biol Cell on November 13, 2013

Authors

Alexander R Kolb1, Patrick G Needham, Cari Rothenberg, Christopher J Guerriero, Paul A Welling, Jeffrey L Brodsky

Author Affiliations

1: Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15261 Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201.

Articles cited by this

(truncated to the top 100)

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast (1998) 23.00

Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene (1995) 13.86

Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol (1988) 13.27

Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression. Nucleic Acids Res (1994) 10.72

Protein oligomerization in the endoplasmic reticulum. Annu Rev Cell Biol (1989) 8.22

Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. Annu Rev Cell Dev Biol (2003) 8.13

The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J (1998) 7.68

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol (2001) 7.68

Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma. Nature (1998) 6.32

Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J Biol Chem (1998) 5.79

Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell (1986) 5.73

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell (2006) 5.54

Inwardly rectifying potassium channels: their structure, function, and physiological roles. Physiol Rev (2010) 5.31

Endosome maturation. EMBO J (2011) 5.22

Membrane scission by the ESCRT-III complex. Nature (2009) 4.66

Synthetic genetic array analysis in Saccharomyces cerevisiae. Methods Mol Biol (2006) 4.45

A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol (1998) 4.41

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation. Nature (1997) 4.40

Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome. Cell (2001) 4.25

Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic (2000) 4.17

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation. Cell (2006) 4.08

Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature (2010) 4.05

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control. J Cell Biol (2004) 3.83

A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene. Circ Res (2005) 3.75

The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting. Nat Cell Biol (2002) 3.62

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science (2011) 3.19

Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae. J Cell Biol (1997) 3.00

Role of ER export signals in controlling surface potassium channel numbers. Science (2001) 2.93

Peripheral protein quality control removes unfolded CFTR from the plasma membrane. Science (2010) 2.92

ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes. Dev Cell (2004) 2.86

A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome. J Cell Biol (1993) 2.65

Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease. J Cell Biol (2001) 2.65

Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell (2006) 2.63

Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell (2002) 2.55

Dissecting the ER-associated degradation of a misfolded polytopic membrane protein. Cell (2008) 2.41

ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Cell (2006) 2.38

CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway. J Virol (1998) 2.38

Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p. Nat Cell Biol (2004) 2.37

Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase. J Cell Sci (2002) 2.36

Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast. Mol Biol Cell (2001) 2.34

Systematic exploration of essential yeast gene function with temperature-sensitive mutants. Nat Biotechnol (2011) 2.26

N-glycan structures: recognition and processing in the ER. Trends Biochem Sci (2009) 2.26

Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell (2007) 2.21

Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes. J Biol Chem (1997) 2.20

Degradation of a mutant secretory protein, alpha1-antitrypsin Z, in the endoplasmic reticulum requires proteasome activity. J Biol Chem (1996) 2.19

The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct. J Biol Chem (1999) 2.17

Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi. Mol Biol Cell (2000) 2.14

Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. J Cell Biol (2002) 2.03

Transmembrane structure of an inwardly rectifying potassium channel. Cell (1999) 2.02

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding. J Cell Biol (2001) 1.99

The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. Physiol Rev (2012) 1.95

Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase. Mol Cell (2009) 1.94

Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins. EMBO J (2004) 1.92

ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1. Dev Cell (2008) 1.91

Regions responsible for the assembly of inwardly rectifying potassium channels. Cell (1996) 1.87

Identification and characterization of five new subunits of TRAPP. Eur J Cell Biol (2000) 1.84

Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems. Traffic (2002) 1.84

Ubiquitin and endocytic internalization in yeast and animal cells. Biochim Biophys Acta (2004) 1.78

Yeast mutants affecting possible quality control of plasma membrane proteins. Mol Cell Biol (1999) 1.77

Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery. Curr Biol (2006) 1.76

A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies. Nat Cell Biol (2002) 1.74

A pathway for targeting soluble misfolded proteins to the yeast vacuole. J Cell Biol (1996) 1.73

Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol Biol Cell (2003) 1.72

Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways. Mol Biol Cell (2003) 1.72

Golgi export of the Kir2.1 channel is driven by a trafficking signal located within its tertiary structure. Cell (2011) 1.71

Protein quality control in the ER: balancing the ubiquitin checkbook. Trends Cell Biol (2011) 1.68

Saccharomyces cerevisiae expresses three functionally distinct homologues of the nramp family of metal transporters. Mol Cell Biol (2000) 1.65

Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole. J Cell Biol (1995) 1.63

Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels: therapeutic implications. J Biol Chem (2006) 1.61

Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells. Proc Natl Acad Sci U S A (1997) 1.61

The Cdc48 machine in endoplasmic reticulum associated protein degradation. Biochim Biophys Acta (2011) 1.60

Structural insight into the ESCRT-I/-II link and its role in MVB trafficking. EMBO J (2007) 1.60

Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol (1997) 1.60

Cholesterol sensitivity and lipid raft targeting of Kir2.1 channels. Biophys J (2004) 1.56

An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport. J Cell Biol (2002) 1.49

Mechanisms for rescue of correctable folding defects in CFTRDelta F508. Mol Biol Cell (2009) 1.46

Drosophila Vps35 function is necessary for normal endocytic trafficking and actin cytoskeleton organisation. J Cell Sci (2007) 1.46

ER-golgi traffic is a prerequisite for efficient ER degradation. Mol Biol Cell (2002) 1.42

Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system. EMBO J (2000) 1.41

Mutation of the Rab6 homologue of Saccharomyces cerevisiae, YPT6, inhibits both early Golgi function and ribosome biosynthesis. J Biol Chem (1996) 1.41

Vps51p links the VFT complex to the SNARE Tlg1p. J Biol Chem (2002) 1.39

Transferrin receptor-like proteins control the degradation of a yeast metal transporter. EMBO J (2006) 1.38

Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p. Mol Biol Cell (2002) 1.37

Small heat-shock proteins select deltaF508-CFTR for endoplasmic reticulum-associated degradation. Mol Biol Cell (2006) 1.24

Selective processing and metabolism of disease-causing mutant prion proteins. PLoS Pathog (2009) 1.22

Misfolded proteins traffic from the endoplasmic reticulum (ER) due to ER export signals. Mol Biol Cell (2006) 1.20

Elimination of defective alpha-factor pheromone receptors. Mol Cell Biol (1997) 1.19

Lysosomal sorting mutants of coronavirus E1 protein, a Golgi membrane protein. J Cell Sci (1990) 1.18

The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones. Mol Biol Cell (2010) 1.17

Cytoplasmic Hsp70 promotes ubiquitination for endoplasmic reticulum-associated degradation of a misfolded mutant of the yeast plasma membrane ATPase, PMA1. J Biol Chem (2007) 1.15

Ubiquitin-mediated targeting of a mutant plasma membrane ATPase, Pma1-7, to the endosomal/vacuolar system in yeast. Mol Biol Cell (2004) 1.14

The mammalian K(IR)2.x inward rectifier ion channel family: expression pattern and pathophysiology. Acta Physiol (Oxf) (2010) 1.11

Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence. Proc Natl Acad Sci U S A (1998) 1.11

Functional expression of a vertebrate inwardly rectifying K+ channel in yeast. Mol Biol Cell (1995) 1.10

Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis. Trends Biochem Sci (2012) 1.09

ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum. Bioessays (2010) 1.08

The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress. Elife (2013) 1.05

In vitro synthesis of novel genes: mutagenesis and recombination by PCR. PCR Methods Appl (1994) 1.05

ESCRT-0 assembles as a heterotetrameric complex on membranes and binds multiple ubiquitinylated cargoes simultaneously. J Biol Chem (2010) 1.01

GGA2- and ubiquitin-dependent trafficking of Arn1, the ferrichrome transporter of Saccharomyces cerevisiae. Mol Biol Cell (2007) 0.98

Articles by these authors

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92

One step at a time: endoplasmic reticulum-associated degradation. Nat Rev Mol Cell Biol (2008) 8.68

From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proc Natl Acad Sci U S A (2008) 3.39

The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum. Traffic (2008) 3.07

Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. Nat Chem Biol (2007) 2.57

Dissecting the ER-associated degradation of a misfolded polytopic membrane protein. Cell (2008) 2.41

Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein. J Biol Chem (2004) 2.41

A stress-responsive system for mitochondrial protein degradation. Mol Cell (2010) 2.05

The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. Physiol Rev (2012) 1.95

Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange. Mol Cell (2005) 1.94

Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD). Bioessays (2003) 1.94

Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ. Mol Biol Cell (2005) 1.94

Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast. Mol Biol Cell (2004) 1.86

Golgi export of the Kir2.1 channel is driven by a trafficking signal located within its tertiary structure. Cell (2011) 1.71

WNK1 kinase isoform switch regulates renal potassium excretion. Proc Natl Acad Sci U S A (2006) 1.65

Nucleotide exchange factor for the yeast Hsp70 molecular chaperone Ssa1p. Mol Cell Biol (2002) 1.62

Survivin is a therapeutic target in Merkel cell carcinoma. Sci Transl Med (2012) 1.61

Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A. J Biol Chem (2003) 1.55

The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum. J Cell Biol (2005) 1.52

Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins. EMBO J (2007) 1.51

Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity. J Biol Chem (2004) 1.51

A J domain virulence effector of Pseudomonas syringae remodels host chloroplasts and suppresses defenses. Curr Biol (2007) 1.50

Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities. Biochem J (2009) 1.46

Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system. Cell (2007) 1.44

Overexpression of yeast Hsp110 homolog Sse1p suppresses ydj1-151 thermosensitivity and restores Hsp90-dependent activity. Mol Biol Cell (2002) 1.44

WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction. J Biol Chem (2009) 1.44

The function of the yeast molecular chaperone Sse1 is mechanistically distinct from the closely related hsp70 family. J Biol Chem (2004) 1.44

A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum. J Biol Chem (2008) 1.44

Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP. Mol Biol Cell (2003) 1.43

Evidence for endocytosis of ROMK potassium channel via clathrin-coated vesicles. Am J Physiol Renal Physiol (2002) 1.39

Uncoupling retro-translocation and degradation in the ER-associated degradation of a soluble protein. EMBO J (2004) 1.38

Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER. J Biol Chem (2003) 1.36

Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for mucolipidosis type IV pathogenesis. J Exp Med (2008) 1.31

Checkpoints in ER-associated degradation: excuse me, which way to the proteasome? Trends Cell Biol (2004) 1.29

Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation. J Cell Biol (2007) 1.29

Roles of molecular chaperones in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). J Biochem (2005) 1.29

Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40. ACS Chem Biol (2010) 1.28

Autophagy: an ER protein quality control process. Autophagy (2006) 1.26

Small heat-shock proteins select deltaF508-CFTR for endoplasmic reticulum-associated degradation. Mol Biol Cell (2006) 1.24

Golgi-associated maturation of very low density lipoproteins involves conformational changes in apolipoprotein B, but is not dependent on apolipoprotein E. J Biol Chem (2007) 1.24

Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium. Am J Physiol Renal Physiol (2011) 1.23

HspBP1, a homologue of the yeast Fes1 and Sls1 proteins, is an Hsc70 nucleotide exchange factor. FEBS Lett (2002) 1.21

SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner. J Biol Chem (2012) 1.21

Adeno-associated virus interactions with B23/Nucleophosmin: identification of sub-nucleolar virion regions. Virology (2006) 1.21

A phosphorylation-dependent export structure in ROMK (Kir 1.1) channel overrides an endoplasmic reticulum localization signal. J Biol Chem (2005) 1.17

The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones. Mol Biol Cell (2010) 1.17

The activities and function of molecular chaperones in the endoplasmic reticulum. Semin Cell Dev Biol (2007) 1.16

An andersen-Tawil syndrome mutation in Kir2.1 (V302M) alters the G-loop cytoplasmic K+ conduction pathway. J Biol Chem (2006) 1.15

Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactions. J Biol Chem (2003) 1.14

The ARH adaptor protein regulates endocytosis of the ROMK potassium secretory channel in mouse kidney. J Clin Invest (2009) 1.13

Antimyeloma Effects of the Heat Shock Protein 70 Molecular Chaperone Inhibitor MAL3-101. J Oncol (2011) 1.11

Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation. Bioorg Med Chem (2007) 1.09

CFTR expression and ER-associated degradation in yeast. Methods Mol Med (2002) 1.07

Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum. Bioorg Med Chem (2009) 1.07

The Hsp110 molecular chaperone stabilizes apolipoprotein B from endoplasmic reticulum-associated degradation (ERAD). J Biol Chem (2007) 1.07

TIP-1 has PDZ scaffold antagonist activity. Mol Biol Cell (2006) 1.06

Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin. Am J Physiol Cell Physiol (2005) 1.03

Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau. Biol Psychiatry (2013) 1.03

Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review. Hepatology (2007) 1.03

Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein-coupled receptor Ste2. Mol Cell Biol (2014) 1.02

Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators. Proc Natl Acad Sci U S A (2011) 1.02

Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain. Proc Natl Acad Sci U S A (2002) 1.02

OCRL1 function in renal epithelial membrane traffic. Am J Physiol Renal Physiol (2009) 1.01

Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels. ACS Chem Neurosci (2013) 1.00

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen. Virus Res (2009) 1.00

Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One (2013) 0.98

Hypertension resistance polymorphisms in ROMK (Kir1.1) alter channel function by different mechanisms. Am J Physiol Renal Physiol (2010) 0.98

Small heat shock protein alphaA-crystallin regulates epithelial sodium channel expression. J Biol Chem (2007) 0.98

Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase. J Biol Chem (2013) 0.98

Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice. J Cell Biol (2007) 0.97

Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70. J Med Chem (2014) 0.97

AP-2-dependent internalization of potassium channel Kir2.3 is driven by a novel di-hydrophobic signal. J Biol Chem (2008) 0.97

Degradation of mutated bovine pancreatic trypsin inhibitor in the yeast vacuole suggests post-endoplasmic reticulum protein quality control. J Biol Chem (2004) 0.97

Cysteine string protein monitors late steps in cystic fibrosis transmembrane conductance regulator biogenesis. J Biol Chem (2006) 0.97

Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex. Am J Physiol Cell Physiol (2002) 0.96

How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: the early history of ERAD. Biochim Biophys Acta (2013) 0.96

Integrated compensatory network is activated in the absence of NCC phosphorylation. J Clin Invest (2015) 0.96

An antisense oligonucleotide against H1 inhibits the classical sodium current but not ICa(TTX) in rat ventricular cells. J Physiol (2003) 0.95

Differential requirements of novel A1PiZ degradation deficient (ADD) genes in ER-associated protein degradation. J Cell Sci (2003) 0.95

The yeast Hsp110, Sse1p, exhibits high-affinity peptide binding. FEBS Lett (2008) 0.95

The endosomal protein-sorting receptor sortilin has a role in trafficking α-1 antitrypsin. Genetics (2012) 0.95

The thiazide-sensitive NaCl cotransporter is targeted for chaperone-dependent endoplasmic reticulum-associated degradation. J Biol Chem (2011) 0.94

Hsp70 and Hsp90 multichaperone complexes sequentially regulate thiazide-sensitive cotransporter endoplasmic reticulum-associated degradation and biogenesis. J Biol Chem (2013) 0.93

Design of a fluorescence polarization assay platform for the study of human Hsp70. Bioorg Med Chem Lett (2008) 0.92

Localization of the BiP molecular chaperone with respect to endoplasmic reticulum foci containing the cystic fibrosis transmembrane conductance regulator in yeast. J Histochem Cytochem (2003) 0.91

Insulin-stimulated degradation of apolipoprotein B100: roles of class II phosphatidylinositol-3-kinase and autophagy. PLoS One (2013) 0.91

ADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly. Mol Biol Cell (2007) 0.91

High-throughput screening identifies a bisphenol inhibitor of SV40 large T antigen ATPase activity. J Biomol Screen (2011) 0.91

Protein disulfide isomerases contribute differentially to the endoplasmic reticulum-associated degradation of apolipoprotein B and other substrates. Mol Biol Cell (2011) 0.90

Phosphatidylinositol 4-phosphate 5-kinase reduces cell surface expression of the epithelial sodium channel (ENaC) in cultured collecting duct cells. J Biol Chem (2007) 0.90

A Cdc48p-associated factor modulates endoplasmic reticulum-associated degradation, cell stress, and ubiquitinated protein homeostasis. J Biol Chem (2010) 0.90

J domain co-chaperone specificity defines the role of BiP during protein translocation. J Biol Chem (2010) 0.90

The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channel. J Biol Chem (2013) 0.89

The Hsp40 molecular chaperone Ydj1p, along with the protein kinase C pathway, affects cell-wall integrity in the yeast Saccharomyces cerevisiae. Genetics (2007) 0.88

Chemical induction of Hsp70 reduces α-synuclein aggregation in neuroglioma cells. ACS Chem Biol (2013) 0.87

Differential localization of mammalian Lin-7 (MALS/Veli) PDZ proteins in the kidney. Am J Physiol Renal Physiol (2004) 0.87