Published in Age (Dordr) on December 13, 2013
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Tequila Regulates Insulin-Like Signaling and Extends Life Span in Drosophila melanogaster. J Gerontol A Biol Sci Med Sci (2015) 0.78
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Resveratrol improves health and survival of mice on a high-calorie diet. Nature (2006) 20.91
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature (2003) 17.52
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science (2000) 12.98
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science (2005) 11.31
Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature (2004) 10.36
Caloric restriction delays disease onset and mortality in rhesus monkeys. Science (2009) 9.84
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science (2004) 7.29
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab (2007) 7.07
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science (2005) 6.69
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab (2008) 6.22
Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature (2007) 5.94
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr Biol (2007) 5.48
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature (2012) 5.00
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab (2010) 4.97
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev (2004) 4.84
Toward a unified theory of caloric restriction and longevity regulation. Mech Ageing Dev (2005) 4.77
Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev (2004) 4.51
Structure of mammalian AMPK and its regulation by ADP. Nature (2011) 4.27
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc Natl Acad Sci U S A (2006) 3.97
Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr Biol (2006) 3.88
Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence. Science (1982) 3.59
Regulation of C. elegans longevity by specific gustatory and olfactory neurons. Neuron (2004) 3.56
Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science (2013) 3.40
Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proc Natl Acad Sci U S A (2006) 3.04
Drosophila germ-line modulation of insulin signaling and lifespan. Proc Natl Acad Sci U S A (2008) 2.31
Development of calorie restriction mimetics as a prolongevity strategy. Ann N Y Acad Sci (2004) 1.92
Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies. Cell Metab (2013) 1.86
Long-lived Indy and calorie restriction interact to extend life span. Proc Natl Acad Sci U S A (2009) 1.63
Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle. FASEB J (2000) 1.63
An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster. Proc Natl Acad Sci U S A (2004) 1.61
Senescence-accelerated mouse (SAM) with special references to neurodegeneration models, SAMP8 and SAMP10 mice. Neurochem Res (2009) 1.26
Relationship between physical activity and life span in the adult housefly, Musca domestica. Exp Gerontol (1981) 1.24
Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster. Rejuvenation Res (2010) 1.23
Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila. PLoS One (2012) 1.19
Age-related changes in learning and memory in the senescence-accelerated mouse (SAM). Physiol Behav (1986) 1.18
Insulin and longevity: antidiabetic biguanides as geroprotectors. Biogerontology (2003) 1.17
Mullerian inhibiting substance acts as a motor neuron survival factor in vitro. Proc Natl Acad Sci U S A (2005) 1.14
Calorie restriction delays lipid oxidative damage in Drosophila melanogaster. Aging Cell (2005) 1.13
beta-Sitosterol modulates antioxidant enzyme response in RAW 264.7 macrophages. Free Radic Biol Med (2005) 1.12
Antioxidant actions of flavonoids: thermodynamic and kinetic analysis. Arch Biochem Biophys (2010) 1.10
The cannabinoid antagonist SR141716A facilitates memory acquisition and consolidation in the mouse elevated T-maze. Neurosci Lett (2005) 1.06
Dietary restriction depends on nutrient composition to extend chronological lifespan in budding yeast Saccharomyces cerevisiae. PLoS One (2013) 1.01
Antioxidant and cognitive promotion effects of anthocyanin-rich mulberry (Morus atropurpurea L.) on senescence-accelerated mice and prevention of Alzheimer's disease. J Nutr Biochem (2009) 0.99
Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea. Free Radic Res (2009) 0.97
Nectarine promotes longevity in Drosophila melanogaster. Free Radic Biol Med (2011) 0.96
Screening of Taiwanese crude drugs for antibacterial activity against Streptococcus mutans. J Ethnopharmacol (1989) 0.90
Dietary restriction of rodents decreases aging rate without affecting initial mortality rate -- a meta-analysis. Aging Cell (2013) 0.89
Curcumin is an early-acting stage-specific inducer of extended functional longevity in Drosophila. Exp Gerontol (2012) 0.89
Early onset of age-related impairment of aversive and appetitive learning in the SAM-P/8 mouse. J Gerontol (1992) 0.85
BMP4 is a peripherally-derived factor for motor neurons and attenuates glutamate-induced excitotoxicity in vitro. PLoS One (2013) 0.85
Apple polyphenols extend the mean lifespan of Drosophila melanogaster. J Agric Food Chem (2011) 0.84
Three new oleanane-type triterpenes from Ludwigia octovalvis with cytotoxic activity against two human cancer cell lines. J Nat Prod (2004) 0.83
Favorable effects of tea on reducing the cognitive deficits and brain morphological changes in senescence-accelerated mice. J Nutr Sci Vitaminol (Tokyo) (2006) 0.82
Inhibitory avoidance acquisition in adult rats exposed to a combination of ethanol and methylmercury during central nervous system development. Behav Brain Res (2010) 0.82
Extension of Drosophila lifespan by Rhodiola rosea through a mechanism independent from dietary restriction. PLoS One (2013) 0.80
Effect of modest caloric restriction on oxidative stress in women, a randomized trial. PLoS One (2012) 0.80
Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM). Neurobiol Aging (1993) 0.79
Acute restriction impairs memory in the elevated T-maze (ETM) and modifies serotonergic activity in the dorsolateral striatum. Behav Brain Res (2008) 0.77
Effects of age and dietary restriction on lifespan and oxidative stress of SAMP8 mice with learning and memory impairments. J Nutr Health Aging (2000) 0.77
Elevated T-maze evaluation of anxiety and memory effects of NMDA/glycine-B site ligands injected into the dorsal periaqueductal gray matter and the superior colliculus of rats. Neuropharmacology (2006) 0.76
Elevated T-maze as an animal model of memory: effects of scopolamine. Behav Pharmacol (2002) 0.76
Toxicological evaluation of 80% methanol extract of Ludwigia octovalvis (Jacq.) P.H. Raven leaves (Onagraceae) in BALB/c mice. J Ethnopharmacol (2012) 0.76
Protective effect of dietary squalene supplementation on mitochondrial function in liver of aged rats. Prostaglandins Leukot Essent Fatty Acids (2007) 0.76
Visualizing long-term memory formation in two neurons of the Drosophila brain. Science (2012) 2.09
NMDA receptors mediate olfactory learning and memory in Drosophila. Curr Biol (2005) 1.82
Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body. Nat Neurosci (2007) 1.58
2-[(1,3-Benzothia-zol-2-yl)imino-meth-yl]phenol. Acta Crystallogr Sect E Struct Rep Online (2009) 1.51
Estrogen: one of the risk factors in milk for prostate cancer. Med Hypotheses (2004) 1.51
Long-lived Indy induces reduced mitochondrial reactive oxygen species production and oxidative damage. Proc Natl Acad Sci U S A (2009) 1.42
Parallel neural pathways mediate CO2 avoidance responses in Drosophila. Science (2013) 1.34
Serotonin-mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila. Proc Natl Acad Sci U S A (2011) 1.27
Insect NMDA receptors mediate juvenile hormone biosynthesis. Proc Natl Acad Sci U S A (2002) 1.08
Antihyperglycemic effect of oolong tea in type 2 diabetes. Diabetes Care (2003) 1.07
The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis. Biomaterials (2011) 1.06
Soy isoflavone intake increases bone mineral density in the spine of menopausal women: meta-analysis of randomized controlled trials. Clin Nutr (2007) 1.03
Effect of milk tripeptides on blood pressure: a meta-analysis of randomized controlled trials. Nutrition (2008) 1.03
Pumpkin (Cucurbita moschata) fruit extract improves physical fatigue and exercise performance in mice. Molecules (2012) 1.01
Incidence and mortality of testicular and prostatic cancers in relation to world dietary practices. Int J Cancer (2002) 1.00
Prediction of patient outcome from Acinetobacter baumannii bacteremia with Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE) II scores. Intern Med (2011) 1.00
Milk consumption is a risk factor for prostate cancer: meta-analysis of case-control studies. Nutr Cancer (2004) 1.00
Antioxidant and cognitive promotion effects of anthocyanin-rich mulberry (Morus atropurpurea L.) on senescence-accelerated mice and prevention of Alzheimer's disease. J Nutr Biochem (2009) 0.99
Milk consumption is a risk factor for prostate cancer in Western countries: evidence from cohort studies. Asia Pac J Clin Nutr (2007) 0.99
The small delta antigen of hepatitis delta virus is an acetylated protein and acetylation of lysine 72 may influence its cellular localization and viral RNA synthesis. Virology (2004) 0.97
Levels of persistent organic pollutants in human milk in two Chinese coastal cities, Tianjin and Yantai: Influence of fish consumption. Chemosphere (2009) 0.94
Expression of tumor necrosis factor-α and interleukin-1β genes in the cochlea and inferior colliculus in salicylate-induced tinnitus. J Neuroinflammation (2011) 0.92
Effects of high-protein diets on body weight, glycaemic control, blood lipids and blood pressure in type 2 diabetes: meta-analysis of randomised controlled trials. Br J Nutr (2013) 0.92
Sarcopenia, and its association with cardiometabolic and functional characteristics in Taiwan: results from I-Lan Longitudinal Aging Study. Geriatr Gerontol Int (2014) 0.92
Age-related skeletal muscle mass loss and physical performance in Taiwan: implications to diagnostic strategy of sarcopenia in Asia. Geriatr Gerontol Int (2013) 0.91
Effects of pre-germinated brown rice on blood glucose and lipid levels in free-living patients with impaired fasting glucose or type 2 diabetes. J Nutr Sci Vitaminol (Tokyo) (2008) 0.91
Spirulina prevents memory dysfunction, reduces oxidative stress damage and augments antioxidant activity in senescence-accelerated mice. J Nutr Sci Vitaminol (Tokyo) (2011) 0.91
Soyfood intake in the prevention of breast cancer risk in women: a meta-analysis of observational epidemiological studies. J Nutr Sci Vitaminol (Tokyo) (2006) 0.91
Prevalence of risk factors for cardiovascular disease and their associations with diet and physical activity in suburban Beijing, China. J Epidemiol (2010) 0.91
Prevalence of cardiovascular risk factors clustering among suburban residents in Beijing, China. Int J Cardiol (2010) 0.91
Effects of magnesium on exercise performance and plasma glucose and lactate concentrations in rats using a novel blood-sampling technique. Appl Physiol Nutr Metab (2009) 0.88
Low-fat milk promotes the development of 7,12-dimethylbenz(A)anthracene (DMBA)-induced mammary tumors in rats. Int J Cancer (2004) 0.88
Establishment of a promising human nucleus pulposus cell line for intervertebral disc tissue engineering. Tissue Eng Part C Methods (2013) 0.88
Polygonum multiflorum extracts improve cognitive performance in senescence accelerated mice. Am J Chin Med (2003) 0.87
Differential effects of Cbl isoforms on Egfr signaling in Drosophila. Mech Dev (2006) 0.87
Potential Osteoporosis Recovery by Deep Sea Water through Bone Regeneration in SAMP8 Mice. Evid Based Complement Alternat Med (2013) 0.87
Effects of moderate and severe intermittent hypoxia on vascular endothelial function and haemodynamic control in sedentary men. Eur J Appl Physiol (2007) 0.87
Long-term administration of Polygonum multiflorum Thunb. reduces cerebral ischemia-induced infarct volume in gerbils. Am J Chin Med (2003) 0.86
Investigation of the mechanism of beta-amyloid fibril formation by kinetic and thermodynamic analyses. Langmuir (2008) 0.86
BMP4 is a peripherally-derived factor for motor neurons and attenuates glutamate-induced excitotoxicity in vitro. PLoS One (2013) 0.85
The effect of diminished osteogenic signals on reduced osteoporosis recovery in aged mice and the potential therapeutic use of adipose-derived stem cells. Biomaterials (2012) 0.85
Non-pharmacological treatment reducing not only behavioral symptoms, but also psychotic symptoms of older adults with dementia: a prospective cohort study in Taiwan. Geriatr Gerontol Int (2013) 0.85
Comparison of microbiological and clinical characteristics based on SCCmec typing in patients with community-onset meticillin-resistant Staphylococcus aureus (MRSA) bacteraemia. Int J Antimicrob Agents (2011) 0.85
Transplantation of embryonic fibroblasts treated with platelet-rich plasma induces osteogenesis in SAMP8 mice monitored by molecular imaging. J Nucl Med (2009) 0.85
Expression of COX-2 and NMDA receptor genes at the cochlea and midbrain in salicylate-induced tinnitus. Laryngoscope (2011) 0.84
Effect of dietary lipids on longevity and memory in the SAMP8 mice. J Nutr Sci Vitaminol (Tokyo) (2011) 0.84
The investigation of recognition interaction between phenylboronate monolayer and glycated hemoglobin using surface plasmon resonance. Anal Biochem (2008) 0.84
Prevalence of overweight/obesity and its associations with hypertension, diabetes, dyslipidemia, and metabolic syndrome: a survey in the suburban area of Beijing, 2007. Obes Facts (2011) 0.84
Expression of NCAM and OCIAD1 in well-differentiated thyroid carcinoma: correlation with the risk of distant metastasis. J Clin Pathol (2011) 0.83
Granulocyte colony-stimulating factor enhances cellular proliferation and motor function recovery on rats subjected to traumatic brain injury. Neurol Res (2010) 0.83
Dengue virus enhances thrombomodulin and ICAM-1 expression through the macrophage migration inhibitory factor induction of the MAPK and PI3K signaling pathways. PLoS One (2013) 0.83
Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract. Int J Biol Sci (2010) 0.83
The development of diabetes mellitus in Wistar rats kept on a high-fat/low-carbohydrate diet for long periods. Endocrine (2003) 0.83
Ginkgo biloba leaf extract (EGb761) combined with neuroprotective agents reduces the infarct volumes of gerbil ischemic brain. Am J Chin Med (2006) 0.83
Troglitazone enhances the hepatotoxicity of acetaminophen by inducing CYP3A in rats. Toxicology (2002) 0.83
A hormone receptor-based transactivator bridges different binary systems to precisely control spatial-temporal gene expression in Drosophila. PLoS One (2012) 0.83
Favorable effects of tea on reducing the cognitive deficits and brain morphological changes in senescence-accelerated mice. J Nutr Sci Vitaminol (Tokyo) (2006) 0.82
Autophagy-related gene 7 is downstream of heat shock protein 27 in the regulation of eye morphology, polyglutamine toxicity, and lifespan in Drosophila. J Biomed Sci (2012) 0.82
Significant association of Ku80 single nucleotide polymorphisms with colorectal cancer susceptibility in Central Taiwan. Anticancer Res (2009) 0.81
Effect of milk on the 7,12-dimethylbenz[a]-anthracene-induced mammary tumor model in rat. Food Chem Toxicol (2007) 0.80
Comparison between patients under hemodialysis with community-onset bacteremia caused by community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus strains. J Microbiol Immunol Infect (2012) 0.80
Chronic effects of different non-esterified fatty acids on pancreatic islets of rats. Endocrine (2006) 0.80
A two-generation reproduction study to assess the effects of cows' milk on reproductive development in male and female rats. Fertil Steril (2004) 0.80
Diversity and wiring variability of visual local neurons in the Drosophila medulla M6 stratum. J Comp Neurol (2014) 0.80
Determination of Schistosoma japonicum circulating antigens in dilution serum by piezoelectric immunosensor and S/N enhancement. Biosens Bioelectron (2008) 0.79
Acupuncture treatment of insomnia by regulating the defensive-qi and strengthening the brain and the spinal cord. J Tradit Chin Med (2010) 0.79
Location, location, location: how does a spermatogonium know it is a spermatogonial stem cell (SSC)? Biol Reprod (2013) 0.78
One-day dietary restriction changes hepatic metabolism and potentiates the hepatotoxicity of carbon tetrachloride and chloroform in rats. Tohoku J Exp Med (2007) 0.78
Synergistic efficacy of magnesium sulfate and FK506 on cerebral ischemia-induced infarct volume in gerbil. Med Sci Monit (2004) 0.78
Nanonized black soybean enhances immune response in senescence-accelerated mice. Int J Nanomedicine (2009) 0.78
Surveillance on secular trends of incidence and mortality for device-associated infection in the intensive care unit setting at a tertiary medical center in Taiwan, 2000-2008: a retrospective observational study. BMC Infect Dis (2012) 0.78
Examining the levels of ganglioside and cholesterol in cell membrane on attenuation the cytotoxicity of beta-amyloid peptide. Colloids Surf B Biointerfaces (2008) 0.78
Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats. Hepatol Res (2005) 0.78
Beneficial effect of Toona sinensis Roemor on improving cognitive performance and brain degeneration in senescence-accelerated mice. Br J Nutr (2006) 0.78
The effects of denaturants on protein conformation and behavior at air/solution interface. Colloids Surf B Biointerfaces (2005) 0.77
Predictors of mortality in surgical patients with Acinetobacter baumannii bacteremia. J Microbiol Immunol Infect (2011) 0.77
Effects of aging and dietary antler supplementation on the calcium-regulating hormones and bone status in ovariectomized SAMP8 mice. Chin J Physiol (2007) 0.77
Beneficial effects of nicotinamide on alcohol-induced liver injury in senescence-accelerated mice. Biofactors (2008) 0.77
[Study on the factors influencing suicidal ideation among medical students in Beijing]. Zhonghua Liu Xing Bing Xue Za Zhi (2008) 0.77
Psychosomatic consideration to the burning mouth syndrome. Psychiatry Clin Neurosci (2014) 0.77
Beneficial effects of different Polygonum multiflorum Thunb. extracts on memory and hippocampus morphology. J Nutr Sci Vitaminol (Tokyo) (2002) 0.77
Müllerian inhibiting substance is anterogradely transported and does not attenuate avulsion-induced death of hypoglossal motor neurons. Exp Neurol (2010) 0.77
Metal ions stabilize a dimeric molten globule state between the open and closed forms of malic enzyme. Biophys J (2007) 0.77
Promoting effects of milk on the development of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in rats. Acta Histochem Cytochem (2007) 0.76
Glucose intolerance induced by a high-fat/low-carbohydrate diet in rats effects of nonesterified fatty acids. Endocrine (2002) 0.76
Overweight is associated with allergy in school children of Taiwan and Vietnam but not Japan. J Med Invest (2005) 0.76
Effect of Monascus-fermented products on learning and memory in the SAMP8 mice. J Nutr Sci Vitaminol (Tokyo) (2007) 0.76
Decreased carbohydrate intake is more important than increased fat intake in the glucose intolerance by a low-carbohydrate/high-fat diet. Diabetes Res Clin Pract (2002) 0.76
Commercial soy milk enhances the development of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats. In Vivo (2007) 0.76
Association of androgen with skeletal muscle mass and muscle function among men and women aged 50 years and older in Taiwan: results from the I-Lan longitudinal aging study. Rejuvenation Res (2013) 0.76
Endophilin B is required for the Drosophila oocyte to endocytose yolk downstream of Oskar. Development (2014) 0.76
[Outcome of pregnancy in women with polycystic ovary syndrome treated by in vitro maturation of immature oocytes]. Zhonghua Fu Chan Ke Za Zhi (2009) 0.76
Blue light induced free radicals from riboflavin on E. coli DNA damage. J Photochem Photobiol B (2012) 0.76
Lie Group Analysis of the Photo-Induced Fluorescence of Drosophila Oogenesis with the Asymmetrically Localized Gurken Protein. PLoS One (2013) 0.75
Stirring-assisted assembly of nanowires at liquid-solid interfaces. Nanotechnology (2013) 0.75
Higher Daily Physical Activities Continue to Preserve Muscle Strength After Mid-Life, But Not Muscle Mass After Age of 75. Medicine (Baltimore) (2016) 0.75
Uterotrophic effects of cow milk in immature ovariectomized Sprague-Dawley rats. Environ Health Prev Med (2009) 0.75
Milk inhibits the regression of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized rats. Nutr Cancer (2008) 0.75
Should adequacy criteria in cervicovaginal cytology be modified after radiotherapy, chemotherapy, or hysterectomy? Cancer Cytopathol (2010) 0.75
Clinical parameters associated with unsatisfactory specimens of conventional cervical smears. Diagn Cytopathol (2011) 0.75