Published in PLoS One on December 11, 2013
The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae. Genetics (2016) 0.77
Fungal KATs/KDACs: A New Highway to Better Antifungal Drugs? PLoS Pathog (2016) 0.75
The Epigenetic Pathways to Ribosomal DNA Silencing. Microbiol Mol Biol Rev (2016) 0.75
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature (2000) 20.54
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature (2003) 17.52
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science (2004) 17.38
Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nat Genet (2001) 13.05
Extrachromosomal rDNA circles--a cause of aging in yeast. Cell (1997) 8.68
Sirtuins in mammals: insights into their biological function. Biochem J (2007) 7.60
Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell (1991) 7.17
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature (2008) 6.02
Mapping global histone acetylation patterns to gene expression. Cell (2004) 5.57
A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA. Cell (1989) 5.48
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol Cell (2004) 5.37
Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell (2002) 4.38
The biochemistry of sirtuins. Annu Rev Biochem (2006) 4.32
Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev (1997) 4.31
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. Cell (1999) 3.98
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. Proc Natl Acad Sci U S A (2000) 3.94
Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene (2007) 3.85
Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus. Genes Dev (2002) 3.09
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases. Trends Pharmacol Sci (2010) 3.05
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature (2012) 2.96
Molecular model for telomeric heterochromatin in yeast. Curr Opin Cell Biol (1997) 2.73
Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing. Genes Dev (2003) 2.58
Recombination regulation by transcription-induced cohesin dissociation in rDNA repeats. Science (2005) 2.36
SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast. Cell (2004) 2.20
The conserved core of a human SIR2 homologue functions in yeast silencing. Mol Biol Cell (1999) 2.07
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.99
A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. EMBO J (2001) 1.95
The art and design of genetic screens: yeast. Nat Rev Genet (2001) 1.92
Chromatin remodeling during Saccharomyces cerevisiae ADH2 gene activation. Mol Cell Biol (1996) 1.81
The Cdc14 phosphatase and the FEAR network control meiotic spindle disassembly and chromosome segregation. Dev Cell (2003) 1.58
Small molecule regulation of Sir2 protein deacetylases. FEBS J (2005) 1.54
Sirtuins at a glance. J Cell Sci (2011) 1.41
SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions. Biochim Biophys Acta (2009) 1.41
The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more. Curr Opin Microbiol (2000) 1.36
SIRT1 and energy metabolism. Acta Biochim Biophys Sin (Shanghai) (2013) 1.25
The effect of replication initiation on gene amplification in the rDNA and its relationship to aging. Mol Cell (2009) 1.24
Sir2 represses endogenous polymerase II transcription units in the ribosomal DNA nontranscribed spacer. Mol Biol Cell (2006) 1.24
Sirtuin activators and inhibitors. Biofactors (2012) 1.19
Properties of promoters cloned randomly from the Saccharomyces cerevisiae genome. Mol Cell Biol (1988) 1.10
The conserved role of sirtuins in chromatin regulation. Int J Dev Biol (2009) 1.08
Sirtuin 1 in malignant transformation: friend or foe? Cancer Lett (2011) 1.06
Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate. Proc Natl Acad Sci U S A (2010) 0.99
Mating-type control in Saccharomyces cerevisiae: isolation and characterization of mutants defective in repression by a1-alpha 2. Mol Cell Biol (1989) 0.90
New alleles of SIR2 define cell-cycle-specific silencing functions. Genetics (2006) 0.86
The A, B, Gs of silencing. Genes Dev (2007) 0.84
H4K16 acetylation affects recombination and ncRNA transcription at rDNA in Saccharomyces cerevisiae. Mol Biol Cell (2012) 0.81