Published in Cell on May 14, 2004
Mechanisms of change in gene copy number. Nat Rev Genet (2009) 9.01
Targeting of cohesin by transcriptionally silent chromatin. Genes Dev (2005) 2.28
Roles of the sister chromatid cohesion apparatus in gene expression, development, and human syndromes. Chromosoma (2006) 2.15
Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer. Genes Dev (2006) 1.98
A germ cell specific gene of the ARGONAUTE family is essential for the progression of premeiotic mitosis and meiosis during sporogenesis in rice. Plant Cell (2007) 1.97
Transgenerational changes in the genome stability and methylation in pathogen-infected plants: (virus-induced plant genome instability). Nucleic Acids Res (2007) 1.93
Trf4 targets ncRNAs from telomeric and rDNA spacer regions and functions in rDNA copy number control. EMBO J (2007) 1.92
Replication fork barriers: pausing for a break or stalling for time? EMBO Rep (2007) 1.78
Cohesin and human disease. Annu Rev Genomics Hum Genet (2008) 1.68
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep (2008) 1.64
A network of multi-tasking proteins at the DNA replication fork preserves genome stability. PLoS Genet (2005) 1.61
Systematic reduction of cohesin differentially affects chromosome segregation, condensation, and DNA repair. Curr Biol (2010) 1.58
Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange. EMBO Rep (2006) 1.51
Cohesin regulation: fashionable ways to wear a ring. Chromosoma (2007) 1.34
Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing. Genes Dev (2005) 1.34
Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast. Cell Mol Life Sci (2011) 1.27
Sir2 represses endogenous polymerase II transcription units in the ribosomal DNA nontranscribed spacer. Mol Biol Cell (2006) 1.24
Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae. PLoS Genet (2011) 1.22
A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae. Genetics (2008) 1.18
Cohesin protects genes against γH2AX Induced by DNA double-strand breaks. PLoS Genet (2012) 1.17
Nutrient starvation promotes condensin loading to maintain rDNA stability. EMBO J (2007) 1.15
Chromatin: linking structure and function in the nucleolus. Chromosoma (2008) 1.14
A tDNA establishes cohesion of a neighboring silent chromatin domain. Genes Dev (2007) 1.14
Diverse mitotic and interphase functions of condensins in Drosophila. Genetics (2005) 1.13
Mitotic exit and separation of mother and daughter cells. Genetics (2012) 1.10
Calorie restriction effects on silencing and recombination at the yeast rDNA. Aging Cell (2009) 1.10
The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase. Mol Biol Cell (2011) 1.09
Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonuclease. Mol Biol Cell (2006) 1.05
Identifying gene-independent noncoding functional elements in the yeast ribosomal DNA by phylogenetic footprinting. Proc Natl Acad Sci U S A (2005) 1.05
Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol (2007) 1.04
Regulation of yeast sirtuins by NAD(+) metabolism and calorie restriction. Biochim Biophys Acta (2009) 1.02
A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan. PLoS Genet (2013) 1.02
Rates of recombination in the ribosomal DNA of apomictically propagated Daphnia obtusa lines. Genetics (2006) 1.01
Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. PLoS Genet (2008) 1.00
Heterochromatin and the cohesion of sister chromatids. Chromosome Res (2009) 0.99
Lager yeasts possess dynamic genomes that undergo rearrangements and gene amplification in response to stress. Curr Genet (2008) 0.96
Chromosome XII context is important for rDNA function in yeast. Nucleic Acids Res (2006) 0.95
Cohesin codes - interpreting chromatin architecture and the many facets of cohesin function. J Cell Sci (2013) 0.94
Condensin loaded onto the replication fork barrier site in the rRNA gene repeats during S phase in a FOB1-dependent fashion to prevent contraction of a long repetitive array in Saccharomyces cerevisiae. Mol Cell Biol (2006) 0.94
Genome-wide analysis of functional sirtuin chromatin targets in yeast. Genome Biol (2013) 0.93
Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast. Mol Cell Biol (2006) 0.92
A novel gene amplification system in yeast based on double rolling-circle replication. EMBO J (2004) 0.91
Epigenetics in Saccharomyces cerevisiae. Cold Spring Harb Perspect Biol (2013) 0.90
Targeted sister chromatid cohesion by Sir2. PLoS Genet (2011) 0.89
Virulence and karyotype analyses of rad52 mutants of Candida albicans: regeneration of a truncated chromosome of a reintegrant strain (rad52/RAD52) in the host. Infect Immun (2005) 0.89
Rtt109 prevents hyper-amplification of ribosomal RNA genes through histone modification in budding yeast. PLoS Genet (2013) 0.89
Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery. Nucleic Acids Res (2011) 0.89
Coordination of tRNA transcription with export at nuclear pore complexes in budding yeast. Genes Dev (2014) 0.88
Sirtuins in epigenetic regulation. Chem Rev (2015) 0.88
Contrasting roles of checkpoint proteins as recombination modulators at Fob1-Ter complexes with or without fork arrest. Eukaryot Cell (2009) 0.87
Cohesinopathies of a feather flock together. PLoS Genet (2013) 0.87
The duplicated deacetylases Sir2 and Hst1 subfunctionalized by acquiring complementary inactivating mutations. Mol Cell Biol (2011) 0.87
Replication fork arrest and rDNA silencing are two independent and separable functions of the replication terminator protein Fob1 of Saccharomyces cerevisiae. J Biol Chem (2010) 0.87
Regulation of ribosomal DNA amplification by the TOR pathway. Proc Natl Acad Sci U S A (2015) 0.86
Cells expressing murine RAD52 splice variants favor sister chromatid repair. Mol Cell Biol (2006) 0.86
How does genome instability affect lifespan?: roles of rDNA and telomeres. Genes Cells (2011) 0.85
RNA polymerase I transcription factors in active yeast rRNA gene promoters enhance UV damage formation and inhibit repair. Mol Cell Biol (2005) 0.85
The Reb1-homologue Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeast. EMBO J (2012) 0.84
Side chain specificity of ADP-ribosylation by a sirtuin. FEBS J (2009) 0.83
Telomere recombination accelerates cellular aging in Saccharomyces cerevisiae. PLoS Genet (2009) 0.83
More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance. Nucleic Acids Res (2016) 0.82
A reduction in age-enhanced gluconeogenesis extends lifespan. PLoS One (2013) 0.82
Mechanism and physiological significance of programmed replication termination. Semin Cell Dev Biol (2014) 0.82
Transcription and recombination: when RNA meets DNA. Cold Spring Harb Perspect Biol (2014) 0.81
Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation. Nat Commun (2015) 0.81
Ribosomal RNA gene repeats, their stability and cellular senescence. Proc Jpn Acad Ser B Phys Biol Sci (2014) 0.81
CTD kinase I is required for the integrity of the rDNA tandem array. Nucleic Acids Res (2006) 0.81
Opposing role of condensin and radiation-sensitive gene RAD52 in ribosomal DNA stability regulation. J Biol Chem (2009) 0.80
Mechanism of regulation of 'chromosome kissing' induced by Fob1 and its physiological significance. Genes Dev (2015) 0.80
The deacetylase Sir2 from the yeast Clavispora lusitaniae lacks the evolutionarily conserved capacity to generate subtelomeric heterochromatin. PLoS Genet (2013) 0.80
Reversible Top1 cleavage complexes are stabilized strand-specifically at the ribosomal replication fork barrier and contribute to ribosomal DNA stability. Nucleic Acids Res (2014) 0.79
Double rolling circle replication (DRCR) is recombinogenic. Genes Cells (2011) 0.79
Evolutionary mobility of the ribosomal DNA array in yeasts. Genome Biol Evol (2013) 0.78
Nucleolar organizer regions: genomic 'dark matter' requiring illumination. Genes Dev (2016) 0.77
The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae. Genetics (2016) 0.77
Sir2 regulates stability of repetitive domains differentially in the human fungal pathogen Candida albicans. Nucleic Acids Res (2016) 0.76
Functional complementation of sir2Δ yeast mutation by the human orthologous gene SIRT1. PLoS One (2013) 0.76
Histone H3 N-terminal acetylation sites especially K14 are important for rDNA silencing and aging. Sci Rep (2016) 0.76
What is your assay for sister-chromatid cohesion? EMBO J (2007) 0.76
Regulation of DNA Replication through Natural Impediments in the Eukaryotic Genome. Genes (Basel) (2017) 0.75
Relationships between rDNA, Nop1 and Sir complex in biotechnologically relevant distillery yeasts. Arch Microbiol (2016) 0.75
A sequence-specific interaction between the Saccharomyces cerevisiae rRNA gene repeats and a locus encoding an RNA polymerase I subunit affects ribosomal DNA stability. Mol Cell Biol (2014) 0.75
Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast. Aging (Albany NY) (2016) 0.75
Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes. Nucleus (2017) 0.75
The Epigenetic Pathways to Ribosomal DNA Silencing. Microbiol Mol Biol Rev (2016) 0.75
Loss of Ubp3 increases silencing, decreases unequal recombination in rDNA, and shortens the replicative life span in Saccharomyces cerevisiae. Mol Biol Cell (2014) 0.75
The Nucleolus: In Genome Maintenance and Repair. Int J Mol Sci (2017) 0.75
DNA replication stress restricts ribosomal DNA copy number. PLoS Genet (2017) 0.75
Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res (2006) 7.93
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol Syst Biol (2006) 5.20
In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes. Mol Cell Biol (2003) 2.88
Transcription-dependent recombination and the role of fork collision in yeast rDNA. Genes Dev (2003) 2.27
Tor pathway regulates Rrn3p-dependent recruitment of yeast RNA polymerase I to the promoter but does not participate in alteration of the number of active genes. Mol Biol Cell (2003) 1.89
Transcription elongation by RNA polymerase I is linked to efficient rRNA processing and ribosome assembly. Mol Cell (2007) 1.59
Replication fork block protein, Fob1, acts as an rDNA region specific recombinator in S. cerevisiae. Genes Cells (2002) 1.56
Silencing in yeast rDNA chromatin: reciprocal relationship in gene expression between RNA polymerase I and II. Mol Cell (2003) 1.55
Cooperation of the N-terminal Helicase and C-terminal endonuclease activities of Archaeal Hef protein in processing stalled replication forks. J Biol Chem (2004) 1.49
Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro. Genes Cells (2003) 1.48
Arabidopsis TEBICHI, with helicase and DNA polymerase domains, is required for regulated cell division and differentiation in meristems. Plant Cell (2006) 1.26
The cis element and factors required for condensin recruitment to chromosomes. Mol Cell (2009) 1.22
Escherichia coli with a linear genome. EMBO Rep (2007) 1.16
Rad23 stabilizes Rad4 from degradation by the Ub/proteasome pathway. Nucleic Acids Res (2004) 1.15
Identifying gene-independent noncoding functional elements in the yeast ribosomal DNA by phylogenetic footprinting. Proc Natl Acad Sci U S A (2005) 1.05
Glucose degradation products (GDP) retard remesothelialization independently of D-glucose concentration. Kidney Int (2003) 0.97
RNA polymerase I transcription obstructs condensin association with 35S rRNA coding regions and can cause contraction of long repeat in Saccharomyces cerevisiae. Genes Cells (2007) 0.95
Condensin loaded onto the replication fork barrier site in the rRNA gene repeats during S phase in a FOB1-dependent fashion to prevent contraction of a long repetitive array in Saccharomyces cerevisiae. Mol Cell Biol (2006) 0.94
Experimental proof of contamination of blood components by (1-->3)-beta-D-glucan caused by filtration with cellulose filters in the manufacturing process. J Artif Organs (2003) 0.93
Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast. Mol Cell Biol (2006) 0.92
A novel gene amplification system in yeast based on double rolling-circle replication. EMBO J (2004) 0.91
Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30. Mol Cell Biol (2008) 0.91
The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively. J Biol Chem (2011) 0.91
Visual analysis of the yeast 5S rRNA gene transcriptome: regulation and role of La protein. Mol Cell Biol (2008) 0.90
Histones are required for transcription of yeast rRNA genes by RNA polymerase I. Proc Natl Acad Sci U S A (2005) 0.90
Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis. PLoS One (2012) 0.89
Enhancement of perineurial repair and inhibition of nerve adhesion by viscous injectable pure alginate sol. Plast Reconstr Surg (2005) 0.89
Purification and assay of upstream activation factor, core factor, Rrn3p, and yeast RNA polymerase I. Methods Enzymol (2003) 0.87
The recognition and modification sites for the bacterial type I restriction systems KpnAI, StySEAI, StySENI and StySGI. Nucleic Acids Res (2004) 0.86
Gene amplification system based on double rolling-circle replication as a model for oncogene-type amplification. Nucleic Acids Res (2011) 0.84
Transcription-mediated hyper-recombination in HOT1. Genes Cells (2004) 0.84
Intercellular localization of occludins and ZO-1 as a solute transport barrier of the mesothelial monolayer. J Artif Organs (2006) 0.83
RNA polymerase I remains intact without subunit exchange through multiple rounds of transcription in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 0.83
Expression of rRNA genes and nucleolus formation at ectopic chromosomal sites in the yeast Saccharomyces cerevisiae. Mol Cell Biol (2006) 0.82
Three-dimensional invasion of epithelial-mesenchymal transition-positive human peritoneal mesothelial cells into collagen gel is promoted by the concentration gradient of fibronectin. Perit Dial Int (2011) 0.80
Multiple-type dynamic culture of highly oriented fiber scaffold for ligament regeneration. J Artif Organs (2012) 0.79
Regulation of osteogenetic differentiation of mesenchymal stem cells by two axial rotational culture. J Artif Organs (2011) 0.79
Amplification of Hot DNA segments in Escherichia coli. Mol Microbiol (2002) 0.79
Double rolling circle replication (DRCR) is recombinogenic. Genes Cells (2011) 0.79
Creation of cross-linked electrospun isotypic-elastin fibers controlled cell-differentiation with new cross-linker. Int J Biol Macromol (2009) 0.78
The behavior of ligament cells cultured on elastin and collagen scaffolds. J Artif Organs (2013) 0.78
Development of a new method for endovascular aortic repair: combination therapy of cell transplantation and stent grafts with a drug delivery system. Circulation (2006) 0.77
Molecular weight of polydisperse icodextrin effects its oncotic contribution to water transport. J Artif Organs (2008) 0.77
Isolation of 4/91 type of infectious bronchitis virus as a new variant in Japan and efficacy of vaccination against 4/91 type field isolate. Avian Dis (2008) 0.76
Effect of viscous injectable pure alginate sol on cultured fibroblasts. Plast Reconstr Surg (2005) 0.76
[Self-reference effect in an independence/remember-know procedure]. Shinrigaku Kenkyu (2004) 0.76
A quantitative determination of magnetic nanoparticle separation using on-off field operation of quadrupole magnetic field-flow fractionation (QMgFFF). Anal Sci (2013) 0.75
Serological studies of infectious bronchitis vaccines against Japanese field isolates of homologous and heterologous genotypes. J Vet Med Sci (2009) 0.75
Characterization of peritoneal dialysis effluent-derived cells: diagnosis of peritoneal integrity. J Artif Organs (2012) 0.75
Expression of mRNA for growth factors and extracellular matrix proteins after injury to cultured peritoneal cells: does the healing process contribute to peritoneal ultrastructural alteration? J Artif Organs (2003) 0.75
[Determination of glycarbylamide residues in chicken tissues by HPLC with post-column reaction]. Shokuhin Eiseigaku Zasshi (2006) 0.75
Human mesenchymal stem cells differentiate to epithelial cells when cultured on thick collagen gel. Biomed Mater Eng (2013) 0.75
[No difference found between cognitive processing of self-face (self-name) and other's face (other's name) using a priming task]. Shinrigaku Kenkyu (2008) 0.75
Release of (1-->3)-beta-D-glucan from depth-type membrane filters and their in vitro effects on proinflammatory cytokine production. Artif Organs (2003) 0.75
Jacalin regulates IgA production by peripheral blood mononuclear cells. Immunotherapy (2012) 0.75