Published in Biochemistry on February 10, 1987
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Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesis. Proc Natl Acad Sci U S A (1989) 1.26
Restricted ability of group B streptococcal C5a-ase to inactivate C5a prepared from different animal species. Infect Immun (1993) 1.15
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The NXSM recombinant inbred strains of mice: genetic profile for 58 loci including the Mtv proviral loci. Genetics (1990) 0.91
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Molecular and expression analysis of complement component C5 in the nurse shark (Ginglymostoma cirratum) and its predicted functional role. Fish Shellfish Immunol (2009) 0.76
Mutants of complement component C3 cleaved by the C4-specific C1-s protease. Proc Natl Acad Sci U S A (1992) 0.75
Large scale isolation of functionally active components of the human complement system. J Biol Chem (1981) 5.26
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Tritium labeling of proteins to high specific radioactivity by reduction methylation. J Biol Chem (1980) 3.04
Evidence for presence of an internal thiolester bond in third component of human complement. Proc Natl Acad Sci U S A (1980) 3.00
Synergistic and additive killing by antimicrobial factors found in human airway surface liquid. Am J Physiol Lung Cell Mol Physiol (2000) 2.55
The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats. Cell (1986) 2.36
Bactericidal activity of mammalian cathelicidin-derived peptides. Infect Immun (2000) 2.24
DNA-binding site of lac repressor probed by dimethylsulfate methylation of lac operator. J Mol Biol (1979) 2.20
Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands. Infect Immun (1999) 2.19
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Purification and properties of 4-hydroxy-4-methyl-2-oxoglutarate aldolase. J Biol Chem (1972) 2.04
Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA. Immunopharmacology (1999) 1.94
Requirements for the solubilization of immune aggregates by complement: assembly of a factor B-dependent C3-convertase on the immune complexes. J Exp Med (1977) 1.79
Amino-terminal sequence of p36 and associated p10: identification of the site of tyrosine phosphorylation and homology with S-100. Proc Natl Acad Sci U S A (1985) 1.72
Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type 2) of human B lymphocytes. Proc Natl Acad Sci U S A (1987) 1.68
Third component of human complement: appearance of a sulfhydryl group following chemical or enzymatic inactivation. Biochemistry (1980) 1.67
Equilibrium constants for the binding of fatty acids with fatty acid-binding proteins from adipocyte, intestine, heart, and liver measured with the fluorescent probe ADIFAB. J Biol Chem (1994) 1.64
Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. J Immunol (2000) 1.59
A fluorescently labeled intestinal fatty acid binding protein. Interactions with fatty acids and its use in monitoring free fatty acids. J Biol Chem (1992) 1.57
Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B. J Immunol (2000) 1.55
Characterization of the human complement (c3b) receptor with a fluid phase C3b dimer. J Immunol (1981) 1.55
Structural analysis of human complement protein H: homology with C4b binding protein, beta 2-glycoprotein I, and the Ba fragment of B2. J Immunol (1986) 1.53
Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma. J Immunol (2001) 1.52
Fifth component of human complement: purification from plasma and polypeptide chain structure. Biochemistry (1979) 1.49
Human serum amyloid A (SAA): biosynthesis and postsynthetic processing of preSAA and structural variants defined by complementary DNA. Biochemistry (1985) 1.49
Third component of human complement: structural analysis of the polypeptide chains of C3 and C3b. Biochemistry (1979) 1.44
Type I human complement C2 deficiency. A 28-base pair gene deletion causes skipping of exon 6 during RNA splicing. J Biol Chem (1992) 1.40
Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. Biochemistry (2000) 1.39
Third component of human complement: structural requirements for its function. Biochemistry (1980) 1.38
Nucleotide sequence analysis of the complement resistance gene from plasmid R100. J Bacteriol (1982) 1.38
Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung. J Immunol (1995) 1.38
Attenuation of experimental autoimmune demyelination in complement-deficient mice. J Immunol (2000) 1.37
Murine protein H is comprised of 20 repeating units, 61 amino acids in length. Proc Natl Acad Sci U S A (1986) 1.37
Nucleotide sequence of complementary DNA and derived amino acid sequence of murine complement protein C3. Philos Trans R Soc Lond B Biol Sci (1984) 1.29
Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. Proc Natl Acad Sci U S A (1985) 1.29
Primary structure of bovine calpactin I heavy chain (p36), a major cellular substrate for retroviral protein-tyrosine kinases: homology with the human phospholipase A2 inhibitor lipocortin. Biochemistry (1986) 1.28
Cutting edge: the absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy. J Immunol (2001) 1.27
Orientation and dynamics of an antimicrobial peptide in the lipid bilayer by solid-state NMR spectroscopy. Biophys J (2001) 1.27
Herpes simplex virus type 1 glycoprotein gC mediates immune evasion in vivo. J Virol (1998) 1.26
Physicochemical characterization of fluid phase (SC5b-9) and membrane derived (MC5b-9) attack complexes of human complement purified by immunoadsorbent affinity chromatography or selective detergent extraction. Mol Immunol (1981) 1.22
The ovine cathelicidin SMAP29 kills ovine respiratory pathogens in vitro and in an ovine model of pulmonary infection. Antimicrob Agents Chemother (2001) 1.22
Characterization of complement resistance in Escherichia coli conferred by the antibiotic resistance plasmid R100. J Immunol (1980) 1.21
Distal recognition site for classical pathway convertase located in the C345C/netrin module of complement component C5. J Immunol (2000) 1.21
Third component of human complement: localization of the internal thiolester bond. Proc Natl Acad Sci U S A (1982) 1.20
Sequence determination of the thiolester site of the fourth component of human complement. Proc Natl Acad Sci U S A (1981) 1.19
cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4). Proc Natl Acad Sci U S A (1983) 1.19
The beta-Cys-gamma-Glu thiolester bond in human C3, C4, and alpha 2-macroglobulin. Springer Semin Immunopathol (1983) 1.18
Molecular heterogeneity of C2 deficiency. N Engl J Med (1992) 1.17
Binding of C3b proceeds by a transesterification reaction at the thiolester site. Nature (1982) 1.17
Fourth component of human complement: studies of an amine-sensitive site comprised of a thiol component. Biochemistry (1981) 1.17
Complete cDNA sequence of the fourth component of murine complement. Proc Natl Acad Sci U S A (1985) 1.16
The measurement of free fatty acid concentration with the fluorescent probe ADIFAB: a practical guide for the use of the ADIFAB probe. Mol Cell Biochem (1999) 1.15
Kinetics of fatty acid interactions with fatty acid binding proteins from adipocyte, heart, and intestine. J Biol Chem (1996) 1.15
Hypersusceptibility of A/J mice to tuberculosis is in part due to a deficiency of the fifth complement component (C5). Scand J Immunol (2000) 1.15
Congeners of SMAP29 kill ovine pathogens and induce ultrastructural damage in bacterial cells. Antimicrob Agents Chemother (2001) 1.14
A novel murine beta -defensin expressed in tongue, esophagus, and trachea. J Biol Chem (2000) 1.14
Preferential expression of variable region heavy chain gene segments by predominant 2,4-dinitrophenyl-specific BALB/c neonatal antibody clonotypes. Proc Natl Acad Sci U S A (1986) 1.13
Expression of C5a-like biological activities by the fifth component of human complement (C5) upon limited digestion with noncomplement enzymes without release of polypeptide fragments. J Exp Med (1983) 1.13
The binding of a spin-labeled triphosphate to hemoglobin. Cold Spring Harb Symp Quant Biol (1972) 1.10
Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis. Antimicrob Agents Chemother (2001) 1.10
Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA. Proc Natl Acad Sci U S A (1984) 1.09
Murine sex-limited protein: complete cDNA sequence and comparison with murine fourth complement component. J Immunol (1985) 1.08
Complement-independent activation of the fifth component (C5) of human complement: limited trypsin digestion resulting in the expression of biological activity. J Immunol (1982) 1.07
States of hemoglobin in solution. Biochemistry (1972) 1.07
Susceptibilities of oral bacteria and yeast to mammalian cathelicidins. Antimicrob Agents Chemother (2001) 1.06
Thermodynamics of fatty acid binding to fatty acid-binding proteins and fatty acid partition between water and membranes measured using the fluorescent probe ADIFAB. J Biol Chem (1995) 1.06
Mechanism of cooperative oxygen binding to hemoglobin (spin-labeled triphosphate-concerted transition model-hemoglobin chesapeake). Proc Natl Acad Sci U S A (1972) 1.05
N-formylpeptide and complement C5a receptors are expressed in liver cells and mediate hepatic acute phase gene regulation. J Exp Med (1995) 1.05
NH2-terminal structure and cleavage of guinea pig pro-C3, the precursor of the third complement component. J Biol Chem (1981) 1.05
The superfamily of C3b/C4b-binding proteins. Fed Proc (1987) 1.04
The C5a receptor is expressed by human renal proximal tubular epithelial cells. Clin Exp Immunol (2000) 1.02
Structure of murine complement component C3. I. Nucleotide sequence of cloned complementary and genomic DNA coding for the beta chain. J Biol Chem (1984) 1.02
cDNA structure of murine C4b-binding protein, a regulatory component of the serum complement system. Biochemistry (1987) 1.01
Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia. J Neuroimmunol (1995) 1.01
The C4 and Slp genes of the complement region of the murine H-2 major histocompatibility complex. Philos Trans R Soc Lond B Biol Sci (1984) 1.01
Structure of murine complement component C3. II. Nucleotide sequence of cloned complementary DNA coding for the alpha chain. J Biol Chem (1984) 1.01
ATPase center of bacteriophage lambda terminase involved in post-cleavage stages of DNA packaging: identification of ATP-interactive amino acids. J Mol Biol (2000) 0.99
Spin-labeled hemoglobin derivatives in solution, polycrystalline suspensions, and single crystals. Biochemistry (1969) 0.97
Chromosomal location of the genes encoding complement components C5 and factor H in the mouse. J Immunol (1986) 0.97
cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I). J Biol Chem (1987) 0.96
Isolation and sequence analysis of a cDNA clone encoding the fifth complement component. J Biol Chem (1985) 0.96
The fifth component of complement (C5) in the mouse. Analysis of the molecular basis for deficiency. J Exp Med (1987) 0.96
Mapping of a retinoic acid-responsive element in the promoter region of the complement factor H gene. J Biol Chem (1990) 0.95
The NMR structure of human beta-defensin-2 reveals a novel alpha-helical segment. Biochemistry (2001) 0.95
Cis- and trans-acting elements required for constitutive and cytokine-regulated expression of the mouse complement C3 gene. Biochem J (1992) 0.94
Factor H. Curr Top Microbiol Immunol (1990) 0.94
TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis. J Immunol (1997) 0.94
Mice constitutive for sex-limited protein (SLP) expression contain multiple Slp gene sequences. J Immunol (1985) 0.93
Inherited complement C3 deficiency: a defect in C3 secretion. Eur J Immunol (1994) 0.93
A role for complement C5 in organism containment and granulomatous response during murine tuberculosis. Scand J Immunol (2001) 0.93