Published in Biochemistry on August 12, 1986
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Characterization of cDNA encoding human placental anticoagulant protein (PP4): homology with the lipocortin family. Proc Natl Acad Sci U S A (1988) 1.18
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Functionally distinct serine phosphorylation sites of p36, the cellular substrate of retroviral protein kinase; differential inhibition of reassociation with p11. EMBO J (1986) 1.04
Structural and functional characterization of endonexin II, a calcium- and phospholipid-binding protein. Proc Natl Acad Sci U S A (1987) 1.03
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Protein kinase C-dependent phosphorylation of annexins I and II in mesangial cells. Biochem J (1993) 0.81
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Caveolin, a protein component of caveolae membrane coats. Cell (1992) 12.50
Detection and quantification of phosphotyrosine in proteins. Methods Enzymol (1983) 11.89
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell (1994) 8.90
Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein. Nature (1985) 8.36
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature (1995) 8.25
Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2. Cell (1989) 8.19
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci U S A (1999) 7.70
A thousand and one protein kinases. Cell (1987) 7.61
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase. Science (1999) 7.60
Oncogene jun encodes a sequence-specific trans-activator similar to AP-1. Nature (1988) 7.45
Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature (1990) 7.34
Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. J Cell Biol (1991) 7.18
An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates. Cell (1979) 7.02
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell (1991) 6.89
Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro. Cell (1989) 6.88
Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus. Cell (1980) 6.76
The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell (1988) 6.75
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature (1992) 6.69
Characterization of Rous sarcoma virus src gene products synthesized in vitro. J Virol (1978) 6.39
Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus. Cell (1981) 5.74
Changes in protein phosphorylation in Rous sarcoma virus-transformed chicken embryo cells. Mol Cell Biol (1981) 5.67
Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo. J Virol (1978) 5.30
Large scale isolation of functionally active components of the human complement system. J Biol Chem (1981) 5.26
Receptor protein-tyrosine kinases and their signal transduction pathways. Annu Rev Cell Biol (1994) 5.24
Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells. Cell (1981) 5.08
Tyr527 is phosphorylated in pp60c-src: implications for regulation. Science (1986) 4.99
Paxillin: a new vinculin-binding protein present in focal adhesions. J Cell Biol (1990) 4.75
A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature (1996) 4.65
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A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1. Mol Cell Biol (1996) 4.61
Monoclonal antibodies to murine gamma-interferon which differentially modulate macrophage activation and antiviral activity. J Immunol (1985) 4.44
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates. EMBO J (1997) 4.39
Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell (1995) 4.32
Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane. Nature (1984) 4.27
Structural basis for phosphoserine-proline recognition by group IV WW domains. Nat Struct Biol (2000) 4.25
Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell (1997) 4.24
Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro. J Biol Chem (1984) 4.20
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell (1991) 3.98
Identification of a nuclear receptor that is activated by farnesol metabolites. Cell (1995) 3.92
C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. J Biol Chem (1984) 3.88
Production of beta-defensins by human airway epithelia. Proc Natl Acad Sci U S A (1998) 3.85
Characterization of T antigens in polyoma-infected and transformed cells. Cell (1978) 3.76
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Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus. Curr Biol (1995) 3.61
Substrate specificity of protein kinase C. Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements. Eur J Biochem (1986) 3.37
A tail of two src's: mutatis mutandis. Cell (1987) 3.28
Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation. Proc Natl Acad Sci U S A (1982) 3.28
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Temperature-sensitive transformation by Rous sarcoma virus and temperature-sensitive protein kinase activity. J Virol (1980) 3.25
Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc Natl Acad Sci U S A (2001) 3.24
Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases. Mol Cell Biol (1996) 3.21
cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1. EMBO J (1989) 3.10
Tritium labeling of proteins to high specific radioactivity by reduction methylation. J Biol Chem (1980) 3.04
Role of methionine in the initiation of haemoglobin synthesis. Nature (1970) 3.02
Evidence for presence of an internal thiolester bond in third component of human complement. Proc Natl Acad Sci U S A (1980) 3.00
Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle. EMBO J (1995) 2.96
Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins. Cell (1982) 2.92
An F-actin- and calmodulin-binding protein from isolated intestinal brush borders has a morphology related to spectrin. Cell (1982) 2.89
Four different classes of retroviruses induce phosphorylation of tyrosines present in similar cellular proteins. Mol Cell Biol (1981) 2.88
Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis. EMBO J (1991) 2.86
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. Cell Growth Differ (2001) 2.85
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement. Nat Struct Biol (2000) 2.85
The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates. J Biol Chem (1975) 2.84
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Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins. Mol Cell Biol (1997) 2.83
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. Mol Cell (1998) 2.83
Inhibition of phospholipase A2 by "lipocortins" and calpactins. An effect of binding to substrate phospholipids. J Biol Chem (1987) 2.75
NeW wrinkles for an old domain. Cell (2000) 2.72
F-actin binding and bundling properties of fimbrin, a major cytoskeletal protein of microvillus core filaments. J Biol Chem (1981) 2.72
Product of in vitro translation of the Rous sarcoma virus src gene has protein kinase activity. J Virol (1979) 2.72
Transcription. A growing coactivator network. Nature (1996) 2.71
c-rel activates but v-rel suppresses transcription from kappa B sites. Proc Natl Acad Sci U S A (1991) 2.65
Erythroid spectrin, brain fodrin, and intestinal brush border proteins (TW-260/240) are related molecules containing a common calmodulin-binding subunit bound to a variant cell type-specific subunit. Proc Natl Acad Sci U S A (1982) 2.63
Protein kinase C phosphorylates pp60src at a novel site. Cell (1985) 2.63
The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein. J Cell Biol (1986) 2.63
Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity. Cell (1992) 2.62
Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J Immunol (1993) 2.56
Synergistic and additive killing by antimicrobial factors found in human airway surface liquid. Am J Physiol Lung Cell Mol Physiol (2000) 2.55
In vitro polyoma DNA synthesis: characterization of a system from infected 3T3 cells. J Virol (1974) 2.52
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol Cell Biol (1998) 2.52
The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms. Proc Natl Acad Sci U S A (1999) 2.51
WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection. Immunity (2001) 2.49
trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors. Mol Cell Biol (1991) 2.48
Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus. Nature (1983) 2.47
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The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell (1991) 2.46
Characterization of the mRNAs for alpha-, beta- and gamma-actin. Cell (1977) 2.44
TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300. Genes Dev (1998) 2.40
In vitro polyoma DNA synthesis: discontinuous chain growth. J Mol Biol (1974) 2.40
Dependence of cyclin E-CDK2 kinase activity on cell anchorage. Science (1996) 2.38