Published in Front Oncol on December 16, 2013
An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis. Nat Commun (2015) 0.95
The RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and Beyond. Front Cell Dev Biol (2016) 0.93
A NAD-dependent glutamate dehydrogenase coordinates metabolism with cell division in Caulobacter crescentus. EMBO J (2015) 0.85
Chromosomal instability, aneuploidy, and cancer. Front Oncol (2014) 0.78
ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science (2003) 10.04
The biology of chromatin remodeling complexes. Annu Rev Biochem (2009) 10.02
Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature (1996) 7.94
The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell (2002) 5.80
A chromatin remodelling complex involved in transcription and DNA processing. Nature (2000) 5.77
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell (2001) 5.33
Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell (2004) 4.76
Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region. J Biol Chem (1995) 4.50
A giant nucleopore protein that binds Ran/TC4. Nature (1995) 4.36
Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. Cell (2001) 4.23
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature (1999) 3.84
Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. Science (1999) 3.66
A Rae1-containing ribonucleoprotein complex is required for mitotic spindle assembly. Cell (2005) 3.65
The conserved Nup107-160 complex is critical for nuclear pore complex assembly. Cell (2003) 3.58
The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. Proc Natl Acad Sci U S A (2000) 3.16
Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores. Mol Cell (2003) 3.01
The RanGAP1-RanBP2 complex is essential for microtubule-kinetochore interactions in vivo. Curr Biol (2004) 2.88
A mitotic lamin B matrix induced by RanGTP required for spindle assembly. Science (2006) 2.87
Role of importin-beta in coupling Ran to downstream targets in microtubule assembly. Science (2001) 2.87
The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis. EMBO J (1996) 2.71
ISWI is an ATP-dependent nucleosome remodeling factor. Mol Cell (1999) 2.68
The ran GTPase regulates mitotic spindle assembly. Curr Biol (1999) 2.66
SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles. J Cell Biol (2002) 2.60
Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran. Science (1999) 2.59
Crm1 is a mitotic effector of Ran-GTP in somatic cells. Nat Cell Biol (2005) 2.56
RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains. J Cell Biol (1999) 2.42
The Ino80 chromatin-remodeling enzyme regulates replisome function and stability. Nat Struct Mol Biol (2008) 2.30
Phosphorylation of Nup98 by multiple kinases is crucial for NPC disassembly during mitotic entry. Cell (2011) 2.28
Global regulation of H2A.Z localization by the INO80 chromatin-remodeling enzyme is essential for genome integrity. Cell (2011) 2.26
Nup358 integrates nuclear envelope breakdown with kinetochore assembly. J Cell Biol (2003) 2.21
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly. Mol Biol Cell (2006) 1.93
The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. EMBO J (2007) 1.92
Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells. Genes Dev (2004) 1.73
Chromatin and the genome integrity network. Nat Rev Genet (2013) 1.72
Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos. Mol Biol Cell (2002) 1.69
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J (2013) 1.58
ISWI remodeling complexes in Xenopus egg extracts: identification as major chromosomal components that are regulated by INCENP-aurora B. Mol Biol Cell (2002) 1.53
Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes. Mol Biol Cell (2003) 1.51
The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell (2012) 1.50
The Nup107-160 complex and gamma-TuRC regulate microtubule polymerization at kinetochores. Nat Cell Biol (2010) 1.50
Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts. J Cell Sci (1999) 1.43
Microtubule assembly during mitosis - from distinct origins to distinct functions? J Cell Sci (2012) 1.42
Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase. J Cell Biol (1984) 1.31
SWR-C and INO80 chromatin remodelers recognize nucleosome-free regions near +1 nucleosomes. Cell (2013) 1.30
Alp7/TACC is a crucial target in Ran-GTPase-dependent spindle formation in fission yeast. Nature (2007) 1.23
The multifaceted proteins Reptin and Pontin as major players in cancer. Biochim Biophys Acta (2010) 1.19
Ran is required before metaphase for spindle assembly and chromosome alignment and after metaphase for chromosome segregation and spindle midbody organization. Mol Biol Cell (2006) 1.15
The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner. Biochem Biophys Res Commun (2010) 1.11
Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability. J Cell Biol (2011) 1.07
Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK. Mol Biol Cell (2011) 1.05
Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability. Cell Mol Life Sci (2010) 1.04
Intracellular transport by an anchored homogeneously contracting F-actin meshwork. Curr Biol (2011) 1.03
The ATP-dependent helicase RUVBL1/TIP49a associates with tubulin during mitosis. Cell Motil Cytoskeleton (2003) 0.97
Xnf7 contributes to spindle integrity through its microtubule-bundling activity. Curr Biol (2005) 0.96
Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Mol Biol Cell (2008) 0.94
ISWI is a RanGTP-dependent MAP required for chromosome segregation. J Cell Biol (2009) 0.92
Nup98-homeodomain fusions interact with endogenous Nup98 during interphase and localize to kinetochores and chromosome arms during mitosis. Mol Biol Cell (2010) 0.92
Expression of ISWI and its binding to chromatin during the cell cycle and early development. J Struct Biol (2002) 0.83
The human Ino80 binds to microtubule via the E-hook of tubulin: implications for the role in spindle assembly. Biochem Biophys Res Commun (2011) 0.79
The cell biology of open and closed mitosis. Nucleus (2013) 0.76