MicroRNA control of high-density lipoprotein metabolism and function.

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Published in Circ Res on January 03, 2014

Authors

Katey J Rayner1, Kathryn J Moore

Author Affiliations

1: From the University of Ottawa Heart Institute, Ottawa, Ontario, Canada (K.J.R.); and Marc and Ruti Bell Vascular Biology and Disease Program, Leon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine (K.J.M.).

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MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62

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miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res (2010) 25.85

High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med (1977) 15.39

Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med (2011) 15.30

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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10

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Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med (2012) 7.93

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat Genet (1999) 7.30

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat Genet (1999) 7.04

MiR-33 contributes to the regulation of cholesterol homeostasis. Science (2010) 6.93

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Protein-lipid relationships in human plasma. II. In atherosclerosis and related conditions. Am J Med (1951) 4.74

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Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. J Clin Invest (2005) 3.25

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Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J Biol Chem (2010) 2.99

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest (1999) 2.77

Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages. Arterioscler Thromb Vasc Biol (2002) 2.64

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