Published in Development on January 08, 2014
Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells. J Biol Chem (2014) 2.18
Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes. Dev Biol (2014) 1.96
Xenbase, the Xenopus model organism database; new virtualized system, data types and genomes. Nucleic Acids Res (2014) 1.47
A CRISPR view of development. Genes Dev (2014) 1.41
Making designer mutants in model organisms. Development (2014) 1.38
Comparison of T7E1 and surveyor mismatch cleavage assays to detect mutations triggered by engineered nucleases. G3 (Bethesda) (2015) 1.13
Targeted gene disruption in Xenopus laevis using CRISPR/Cas9. Cell Biosci (2015) 1.02
Research proceedings on amphibian model organisms. Dongwuxue Yanjiu (2016) 0.97
CRISPR/Cas9-mediated gene knockout in the ascidian Ciona intestinalis. Dev Growth Differ (2014) 0.91
CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus. Dev Biol (2015) 0.90
Cas9-based genome editing in Xenopus tropicalis. Methods Enzymol (2014) 0.89
Generation of genomic deletions in mammalian cell lines via CRISPR/Cas9. J Vis Exp (2014) 0.87
Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients. Dev Biol (2015) 0.87
Functional genetics for all: engineered nucleases, CRISPR and the gene editing revolution. Evodevo (2014) 0.86
Application of CRISPR/Cas9 for biomedical discoveries. Cell Biosci (2015) 0.82
CRISPR/Cas9-mediated mutagenesis in the sea lamprey Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates. Development (2015) 0.81
Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character. Dev Biol (2014) 0.81
CRISPR/Cas9 as tool for functional study of genes involved in preimplantation embryo development. PLoS One (2015) 0.79
Budgett's frog (Lepidobatrachus laevis): A new amphibian embryo for developmental biology. Dev Biol (2015) 0.79
The Expression of TALEN before Fertilization Provides a Rapid Knock-Out Phenotype in Xenopus laevis Founder Embryos. PLoS One (2015) 0.79
Differential levels of Neurod establish zebrafish endocrine pancreas cell fates. Dev Biol (2015) 0.79
Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus). Aquat Toxicol (2014) 0.78
Development of a new approach for targeted gene editing in primordial germ cells using TALENs in Xenopus. Biol Open (2015) 0.78
Expanding the genetic toolkit in Xenopus: Approaches and opportunities for human disease modeling. Dev Biol (2016) 0.77
Generation of a Xenopus laevis F1 albino J strain by genome editing and oocyte host-transfer. Dev Biol (2016) 0.77
Xenopus as a Model for GI/Pancreas Disease. Curr Pathobiol Rep (2015) 0.77
Xenopus laevis as a model system to study cytoskeletal dynamics during axon pathfinding. Genesis (2017) 0.77
Manipulation and in vitro maturation of Xenopus laevis oocytes, followed by intracytoplasmic sperm injection, to study embryonic development. J Vis Exp (2015) 0.77
A requirement for hedgehog signaling in thyroid hormone-induced postembryonic intestinal remodeling. Cell Biosci (2015) 0.77
Exploring the functions of nonclassical MHC class Ib genes in Xenopus laevis by the CRISPR/Cas9 system. Dev Biol (2016) 0.76
Evolution of Heat Sensors Drove Shifts in Thermosensation between Xenopus Species Adapted to Different Thermal Niches. J Biol Chem (2016) 0.76
Frogs as integrative models for understanding digestive organ development and evolution. Semin Cell Dev Biol (2016) 0.76
Foxn4 promotes gene expression required for multiple motile cilia formation. Development (2016) 0.76
Making muscle: Morphogenetic movements and molecular mechanisms of myogenesis in Xenopus laevis. Semin Cell Dev Biol (2016) 0.75
Expression of the NS5 (VPg) Protein of Murine Norovirus Induces a G1/S Phase Arrest. PLoS One (2016) 0.75
An optimized method for cryogenic storage of Xenopus sperm to maximise the effectiveness of research using genetically altered frogs. Theriogenology (2017) 0.75
Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos. Cell Biosci (2016) 0.75
Leapfrogging: primordial germ cell transplantation permits recovery of CRISPR/Cas9-induced mutations in essential genes. Development (2016) 0.75
Accelerated genome engineering through multiplexing. Wiley Interdiscip Rev Syst Biol Med (2015) 0.75
Acetylcholinesterase plays a non-neuronal, non-esterase role in organogenesis. Development (2017) 0.75
High efficiency non-mosaic CRISPR mediated knock-in and mutations in F0 Xenopus. Development (2017) 0.75
Histone methyltransferase Dot1L is a coactivator for thyroid hormone receptor during Xenopus development. FASEB J (2017) 0.75
Distinct cis-acting regions control six6 expression during eye field and optic cup stages of eye formation. Dev Biol (2017) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes. Invest Ophthalmol Vis Sci (2012) 4.11
Hypoxia-inducible factor-1alpha induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition. Kidney Int (2009) 2.86
Draft genome of the wheat A-genome progenitor Triticum urartu. Nature (2013) 2.86
HIV prevalence in China: integration of surveillance data and a systematic review. Lancet Infect Dis (2013) 2.82
miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells. Cancer Lett (2008) 2.81
catena-Poly[[(pyridin-4-ol-kappaN)silver(I)]-mu-pyridin-4-olato-kappa2N:O]. Acta Crystallogr C (2004) 2.66
Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proc Natl Acad Sci U S A (2012) 2.53
Hepatitis C virus infection in former commercial plasma/blood donors in rural Shanxi Province, China: the China Integrated Programs for Research on AIDS. J Infect Dis (2005) 2.47
Marijuana use and the risk of lung and upper aerodigestive tract cancers: results of a population-based case-control study. Cancer Epidemiol Biomarkers Prev (2006) 2.32
A tale of two clades: monkeypox viruses. J Gen Virol (2005) 2.24
HIV and syphilis prevalence among men who have sex with men: a cross-sectional survey of 61 cities in China. Clin Infect Dis (2013) 2.24
Prediction of the phenotypic effects of non-synonymous single nucleotide polymorphisms using structural and evolutionary information. Bioinformatics (2005) 2.21
Cardiac glycoside downregulates NHE3 activity and expression in LLC-PK1 cells. Am J Physiol Renal Physiol (2005) 2.18
Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing. Nat Biotechnol (2011) 2.10
Medically unexplained dyspnea: psychophysiological characteristics and role of breathing therapy. Chin Med J (Engl) (2004) 2.05
Severe eczema vaccinatum in a household contact of a smallpox vaccinee. Clin Infect Dis (2008) 2.00
PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res (2006) 1.96
CTCF-dependent enhancer-blocking by alternative chromatin loop formation. Proc Natl Acad Sci U S A (2008) 1.90
Well-designed strategy to construct helical silver(I) coordination polymers from flexible unsymmetrical bis(pyridyl) ligands: syntheses, structures, and properties. Inorg Chem (2013) 1.89
CTCFBSDB: a CTCF-binding site database for characterization of vertebrate genomic insulators. Nucleic Acids Res (2007) 1.89
nsSNPAnalyzer: identifying disease-associated nonsynonymous single nucleotide polymorphisms. Nucleic Acids Res (2005) 1.87
Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in glioma. Mol Cancer (2014) 1.81
Mutation in TRMU related to transfer RNA modification modulates the phenotypic expression of the deafness-associated mitochondrial 12S ribosomal RNA mutations. Am J Hum Genet (2006) 1.79
Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression. Genome Res (2005) 1.77
Type 1 and type 2 T-cell profiles in idiopathic thrombocytopenic purpura. Haematologica (2005) 1.75
Noncanonical autophagy promotes the visual cycle. Cell (2013) 1.74
Community engagement and informed consent in the International HapMap project. Community Genet (2007) 1.73
Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. Blood (2008) 1.70
Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1. J Mol Med (Berl) (2002) 1.70
PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways. Nucleic Acids Res (2013) 1.67
The expression of CRM1 is associated with prognosis in human osteosarcoma. Oncol Rep (2009) 1.64
Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. Am J Pathol (2004) 1.64
Prenatal diagnosis and in utero treatment of torsades de pointes associated with congenital long QT syndrome. Am J Cardiol (2003) 1.61
Silencing stathmin gene expression by survivin promoter-driven siRNA vector to reverse malignant phenotype of tumor cells. Cancer Biol Ther (2006) 1.60
Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat Cell Biol (2003) 1.58
Hepatitis E seroprevalence and seroconversion among US military service members deployed to Afghanistan. J Infect Dis (2010) 1.53
Two-dimensional standing wave total internal reflection fluorescence microscopy: superresolution imaging of single molecular and biological specimens. Biophys J (2007) 1.53
Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells. Mol Cell Proteomics (2007) 1.51
I-SceI meganuclease-mediated transgenesis in Xenopus. Dev Dyn (2006) 1.51
Abnormality of CD4(+)CD25(+) regulatory T cells in idiopathic thrombocytopenic purpura. Eur J Haematol (2007) 1.50
A two-dimensional manganese(II) coordination polymer: poly[[diaquamanganese(II)]-mu-4,4-bipyridine-kappa(2)N:N'-mu-(p-phenylenedioxydiacetato)-kappa2O:O']. Acta Crystallogr C (2004) 1.50
Role for the alternative complement pathway in ischemia/reperfusion injury. Am J Pathol (2003) 1.49
PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits. Nucleic Acids Res (2011) 1.49
Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis (2006) 1.47
Incidence of mumps and immunity to measles, mumps and rubella among US military recruits, 2000-2004. Vaccine (2007) 1.47
Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits. Hum Mol Genet (2005) 1.46
Inferring gene transcriptional modulatory relations: a genetical genomics approach. Hum Mol Genet (2005) 1.43
Atrial and ventricular rate response and patterns of heart rate acceleration during maternal-fetal terbutaline treatment of fetal complete heart block. Am J Cardiol (2007) 1.43
Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue. Genes Dev (2006) 1.43
Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers. Proc Natl Acad Sci U S A (2007) 1.43
Suspected pulmonary tuberculosis exposure at a remote U.S. army camp in northeastern Afghanistan, 2007. Mil Med (2008) 1.40
Impacts of HIV infection and HAART use on quality of life. Qual Life Res (2006) 1.39
neo-Clerodane diterpenes from Ajuga ciliata Bunge and their neuroprotective activities. Fitoterapia (2011) 1.38
Extracorporeal shock wave lithotripsy is effective in treating single melamine induced urolithiasis in infants and young children. J Urol (2012) 1.38
Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk. Carcinogenesis (2011) 1.37
GeneInfoViz: constructing and visualizing gene relation networks. In Silico Biol (2004) 1.35
The effect of tourniquet use on hidden blood loss in total knee arthroplasty. Int Orthop (2008) 1.34
Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. Nucleic Acids Res (2014) 1.34
Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). Carcinogenesis (2008) 1.32
Poly[[diaquabarium(II)]-mu5-m-phenylenedioxydiacetato]: a three-dimensional barium(II) coordination polymer. Acta Crystallogr C (2005) 1.31
Metagenomic sequencing reveals microbiota and its functional potential associated with periodontal disease. Sci Rep (2013) 1.30
CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis. Cancer Res (2009) 1.27
Video-assisted thoracoscopic surgery is more favorable than thoracotomy for administration of adjuvant chemotherapy after lobectomy for non-small cell lung cancer. World J Surg Oncol (2011) 1.26
Monitoring age-related susceptibility of young mice to oral Salmonella enterica serovar Typhimurium infection using an in vivo murine model. Pediatr Res (2005) 1.26
Mouse gammadelta T cells are capable of expressing MHC class II molecules, and of functioning as antigen-presenting cells. J Neuroimmunol (2008) 1.25
Boron-doped carbon nanotubes as metal-free electrocatalysts for the oxygen reduction reaction. Angew Chem Int Ed Engl (2011) 1.24
Anti-inflammatory role of IL-17 in experimental autoimmune uveitis. J Immunol (2009) 1.23
Brominated furanones inhibit biofilm formation by Salmonella enterica serovar Typhimurium. Appl Environ Microbiol (2008) 1.22
Visualization of Proteus mirabilis within the matrix of urease-induced bladder stones during experimental urinary tract infection. Infect Immun (2002) 1.22
WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation. EMBO J (2008) 1.22
Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma. Hum Mutat (2008) 1.22
Requirement and functional redundancy of Ib subgroup bHLH proteins for iron deficiency responses and uptake in Arabidopsis thaliana. Mol Plant (2012) 1.22
Retinoic acid synthesis and functions in early embryonic development. Cell Biosci (2012) 1.21
Vapor-solid growth and characterization of aluminum nitride nanocones. J Am Chem Soc (2005) 1.20
Synthesis of single-crystalline alpha-Si(3)N(4) nanobelts by extended vapour-liquid-solid growth. Nanotechnology (2005) 1.20
Hazard of recurrence among women after primary breast cancer treatment--a 10-year follow-up using data from SEER-Medicare. Cancer Epidemiol Biomarkers Prev (2012) 1.20
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. Lab Invest (2007) 1.19
MicroRNA-124 suppresses breast cancer cell growth and motility by targeting CD151. Cell Physiol Biochem (2013) 1.17
GC content-based pan-pox universal PCR assays for poxvirus detection. J Clin Microbiol (2009) 1.15
Association of EPHA2 polymorphisms and age-related cortical cataract in a Han Chinese population. Mol Vis (2011) 1.15
Comparison of outcomes for laparoscopically assisted and open radical distal gastrectomy with lymphadenectomy for advanced gastric cancer. Surg Endosc (2011) 1.15
AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion. Proc Natl Acad Sci U S A (2005) 1.14
Generation of gene disruptions by transcription activator-like effector nucleases (TALENs) in Xenopus tropicalis embryos. Cell Biosci (2013) 1.14
Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC). PLoS One (2012) 1.13
CTCFBSDB 2.0: a database for CTCF-binding sites and genome organization. Nucleic Acids Res (2012) 1.13
Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice. J Biol Chem (2004) 1.13
Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer. PLoS One (2011) 1.12
Rational design of a flavivirus vaccine by abolishing viral RNA 2'-O methylation. J Virol (2013) 1.12
Design of compensation coils for EMI suppression in magnetostrictive linear position sensors. Sensors (Basel) (2012) 1.11
Delineation of the Salmonella enterica serovar Typhimurium HilA regulon through genome-wide location and transcript analysis. J Bacteriol (2007) 1.11
Lack of evidence for changing virulence of HIV-1 in North America. PLoS One (2008) 1.11
Plasmodium falciparum populations from northeastern Myanmar display high levels of genetic diversity at multiple antigenic loci. Acta Trop (2012) 1.10
Rates of HIV, syphilis, and HCV infections among different demographic groups of female sex workers in Guangxi China: evidence from 2010 national sentinel surveillance data. AIDS Care (2013) 1.09