Published in Channels (Austin) on January 13, 2014
ATP release through pannexon channels. Philos Trans R Soc Lond B Biol Sci (2015) 0.92
Chemotherapeutic drugs induce ATP release via caspase-gated pannexin-1 channels and a caspase/pannexin-1-independent mechanism. J Biol Chem (2014) 0.89
Do not let death do us part: 'find-me' signals in communication between dying cells and the phagocytes. Cell Death Differ (2016) 0.82
Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides. J Immunol (2016) 0.82
Emerging concepts regarding pannexin 1 in the vasculature. Biochem Soc Trans (2015) 0.78
Perspectives on the role of Pannexin 1 in neural precursor cell biology. Neural Regen Res (2016) 0.75
Expression and function of pannexins in the inner ear and hearing. BMC Cell Biol (2016) 0.75
D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels. Nat Commun (2017) 0.75
Molecular physiology of P2X receptors. Physiol Rev (2002) 13.61
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J (2006) 8.12
Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity (2007) 6.75
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature (2009) 4.98
Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Lett (2004) 4.73
Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature (2010) 4.10
Pannexin 1 in erythrocytes: function without a gap. Proc Natl Acad Sci U S A (2006) 4.03
The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proc Natl Acad Sci U S A (2007) 4.01
Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci U S A (2003) 3.96
Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium. FEBS Lett (2005) 3.89
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett (2007) 3.19
TRPV1 shows dynamic ionic selectivity during agonist stimulation. Nat Neurosci (2008) 3.08
Ischemia opens neuronal gap junction hemichannels. Science (2006) 3.00
The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J Biol Chem (2009) 2.90
A ubiquitous family of putative gap junction molecules. Curr Biol (2000) 2.77
P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. J Immunol (2008) 2.72
Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation. J Immunol (2011) 2.67
The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins. Genomics (2004) 2.54
Afferent neurotransmission mediated by hemichannels in mammalian taste cells. EMBO J (2007) 2.51
P2X7 receptor-Pannexin1 complex: pharmacology and signaling. Am J Physiol Cell Physiol (2008) 2.49
Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus. Science (2008) 2.46
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J Pharmacol Exp Ther (2008) 2.42
Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. J Cell Sci (2007) 2.41
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nat Med (2012) 2.25
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature (2013) 2.08
Pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membrane. J Biol Chem (2007) 2.05
P2X7 receptor-mediated release of excitatory amino acids from astrocytes. J Neurosci (2003) 1.94
Evolution of gap junction proteins--the pannexin alternative. J Exp Biol (2005) 1.88
A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP. Am J Physiol Cell Physiol (2008) 1.86
Pannexin channels are not gap junction hemichannels. Channels (Austin) (2011) 1.84
Tumor-suppressive effects of pannexin 1 in C6 glioma cells. Cancer Res (2007) 1.70
The biochemistry and function of pannexin channels. Biochim Biophys Acta (2012) 1.70
Biphasic currents evoked by chemical or thermal activation of the heat-gated ion channel, TRPV3. J Biol Chem (2005) 1.67
The P2X7 receptor channel pore dilates under physiological ion conditions. J Gen Physiol (2008) 1.57
Pannexins in ischemia-induced neurodegeneration. Proc Natl Acad Sci U S A (2011) 1.55
Spreading depression triggers headache by activating neuronal Panx1 channels. Science (2013) 1.52
Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region. J Biol Chem (2012) 1.44
Targeting pannexin1 improves seizure outcome. PLoS One (2011) 1.43
Gap junctional proteins of animals: the innexin/pannexin superfamily. Prog Biophys Mol Biol (2007) 1.41
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other. J Biol Chem (2010) 1.39
Stimulation of rat erythrocyte P2X7 receptor induces the release of epoxyeicosatrienoic acids. Br J Pharmacol (2007) 1.34
Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation. Am J Physiol Cell Physiol (2010) 1.28
Patch-clamp coordinated spectroscopy shows P2X2 receptor permeability dynamics require cytosolic domain rearrangements but not Panx-1 channels. Proc Natl Acad Sci U S A (2008) 1.28
Thrombin promotes release of ATP from lung epithelial cells through coordinated activation of rho- and Ca2+-dependent signaling pathways. J Biol Chem (2009) 1.27
SCAM analysis of Panx1 suggests a peculiar pore structure. J Gen Physiol (2010) 1.25
Pannexin: from discovery to bedside in 11±4 years? Brain Res (2012) 1.24
ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes. Glia (2012) 1.22
Pannexin1 regulates α1-adrenergic receptor- mediated vasoconstriction. Circ Res (2011) 1.21
Trafficking dynamics of glycosylated pannexin 1 proteins. Cell Commun Adhes (2008) 1.20
The ATP permeability of pannexin 1 channels in a heterologous system and in mammalian taste cells is dispensable. J Cell Sci (2012) 1.16
Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes. Am J Physiol Cell Physiol (2008) 1.13
Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins. J Biol Chem (2013) 1.10
Physiological mechanisms for the modulation of pannexin 1 channel activity. J Physiol (2012) 1.07
Pannexin1 stabilizes synaptic plasticity and is needed for learning. PLoS One (2012) 1.07
ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages. J Cell Sci (2008) 1.03
Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions. J Biol Chem (2010) 1.03
Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum. Cell Signal (2010) 1.01
P2X7 receptor-pannexin 1 hemichannel association: effect of extracellular calcium on membrane permeabilization. J Mol Neurosci (2011) 1.01
Pannexin 1 forms an anion-selective channel. Pflugers Arch (2012) 1.00
P2X7 receptor activates multiple selective dye-permeation pathways in RAW 264.7 and human embryonic kidney 293 cells. Mol Pharmacol (2009) 1.00
Intrarenal localization of the plasma membrane ATP channel pannexin1. Am J Physiol Renal Physiol (2012) 0.99
S-nitrosylation inhibits pannexin 1 channel function. J Biol Chem (2012) 0.96
Is pannexin the pore associated with the P2X7 receptor? Naunyn Schmiedebergs Arch Pharmacol (2013) 0.95
Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype. J Biol Chem (2012) 0.94
Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1. J Cell Sci (2012) 0.93
Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation. Am J Physiol Heart Circ Physiol (2012) 0.87
Characterization of novel Pannexin 1 isoforms from rat pituitary cells and their association with ATP-gated P2X channels. Gen Comp Endocrinol (2011) 0.86
Expansion of the constant field equation to include both divalent and monovalent ions. Ala J Med Sci (1972) 0.85
Pathways regulating the trafficking and turnover of pannexin1 protein and the role of the C-terminal domain. J Biol Chem (2011) 0.82