Metastatic melanoma - a review of current and future drugs.

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Published in Drugs Context on November 19, 2012

Authors

Tiago Rodrigues Velho1

Author Affiliations

1: Faculty of Lisbon, University of Lisbon, Lisbon, Portugal.

Associated clinical trials:

Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma | NCT01024231

RADVAX™: A STRATIFIED PHASE I/II DOSE ESCALATION TRIAL OF HYPOFRACTIONATED RADIOTHERAPY FOLLOWED BY IPILIMUMAB IN METASTATIC MELANOMA | NCT01497808

A Study to Evaluate RAF265, an Oral Drug Administered to Subjects With Locally Advanced or Metastatic Melanoma (CHIR-265-MEL01) | NCT00304525

Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma | NCT00349206

Combination of Anti-CD137 & Ipilimumab in Patients With Melanoma | NCT00803374

Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery | NCT00281957

A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients With Solid Tumors and in Combination With Temozolomide in Patients With Advanced and/or Metastatic Melanoma | NCT00121680

E7080 (Lenvatinib) in Combination With Dacarbazine Versus Dacarbazine Alone as First Line Therapy in Patients With Stage IV Melanoma | NCT01133977

Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma | NCT01303341

A Two Arm Trial of Axitinib and Carboplatin/Paclitaxel in Melanoma (CC# 10852) | NCT01174238

An Expanded Cohort Trial of Bortezomib and Sorafenib in Advanced Malignant Melanoma | NCT01078961

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