Published in J Exp Med on December 01, 1987
La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J Virol (1993) 5.89
A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. Mol Biol Cell (2002) 5.34
A perinucleolar compartment contains several RNA polymerase III transcripts as well as the polypyrimidine tract-binding protein, hnRNP I. J Cell Biol (1995) 2.53
Autoantibodies to tumor-associated antigens: reporters from the immune system. Immunol Rev (2008) 2.30
Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: role of La autoantigen in XIAP translation. Mol Cell Biol (2000) 2.22
The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2. Mol Cell Biol (2003) 1.74
Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding. Nucleic Acids Res (1989) 1.72
Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex. J Exp Med (1993) 1.64
Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor. J Exp Med (1991) 1.63
Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1. J Clin Invest (1989) 1.61
Subcellular relocalization of a trans-acting factor regulates XIAP IRES-dependent translation. Mol Biol Cell (2007) 1.50
Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells. Proc Natl Acad Sci U S A (1998) 1.49
3'-end-dependent formation of U6 small nuclear ribonucleoprotein particles in Xenopus laevis oocyte nuclei. Mol Cell Biol (1992) 1.44
An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus. J Exp Med (1993) 1.31
A search for structurally similar cellular internal ribosome entry sites. Nucleic Acids Res (2007) 1.29
Properties of the ribosomal P2 protein autoantigen are similar to those of foreign protein antigens. Proc Natl Acad Sci U S A (1988) 1.22
Biochemical and immunological heterogeneity of the Ro ribonucleoprotein particles. Analysis with sera specific for the RohY5 particle. J Clin Invest (1989) 1.18
The role of an autoantigen, histidyl-tRNA synthetase, in the induction and maintenance of autoimmunity. Proc Natl Acad Sci U S A (1990) 1.15
Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen. J Exp Med (1992) 1.11
Autoimmune response to the Ro/SSA particle is directed to the human antigen. Clin Exp Immunol (1989) 1.09
Autoantibodies to RNA polymerase II are common in systemic lupus erythematosus and overlap syndrome. Specific recognition of the phosphorylated (IIO) form by a subset of human sera. J Clin Invest (1994) 1.07
Interactions between autoimmunity and molecular and cell biology. Bridges between clinical and basic sciences. J Clin Invest (1989) 1.04
Insights into native epitopes of proliferating cell nuclear antigen using recombinant DNA protein products. J Exp Med (1990) 1.00
Autoimmunity and apoptosis. J Exp Med (1994) 0.97
The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo. RNA (2001) 0.94
Relative paradigms between autoantibodies in lupus and autoantibodies in cancer. Clin Exp Immunol (2003) 0.90
Identification of a human-specific epitope in a conserved region of the La/SS-B autoantigen. J Clin Invest (1993) 0.88
Characterization of murine monoclonal antibodies against 60-kD Ro/SS-A and La/SS-B autoantigens. Clin Exp Immunol (1995) 0.87
Antinuclear antibodies and juvenile chronic arthritis (JCA): search for a specific autoantibody associated with JCA. Ann Rheum Dis (1991) 0.85
Human autoantibodies to poly(adenosine diphosphate-ribose) polymerase recognize cross-reactive epitopes associated with the catalytic site of the enzyme. J Clin Invest (1989) 0.81
Inhibition of enzyme function by human autoantibodies to an autoantigen pyruvate dehydrogenase E2: different epitope for spontaneous human and induced rabbit autoantibodies. Clin Exp Immunol (1990) 0.79
Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines. Neurobiol Aging (2008) 0.79
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1979) 14.61
A simplified method for cyanogen bromide activation of agarose for affinity chromatography. Anal Biochem (1974) 13.32
Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis. Methods Enzymol (1983) 12.78
Purified lupus antigen La recognizes an oligouridylate stretch common to the 3' termini of RNA polymerase III transcripts. Cell (1984) 4.64
Differentiation and characterization of autoantibodies and their antigens in Sjögren's syndrome. Arthritis Rheum (1976) 4.02
Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La lupus antibodies. Cell (1982) 3.76
A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences. Proc Natl Acad Sci U S A (1981) 3.68
Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen. Arthritis Rheum (1974) 2.99
Interaction between VA RNA and the lupus antigen La: formation of a ribonucleoprotein particle in vitro. Proc Natl Acad Sci U S A (1982) 2.83
High titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. Science (1986) 2.50
Monoclonal antibodies to a nuclear protein (PCNA/cyclin) associated with DNA replication. Exp Cell Res (1987) 2.13
Autoantibody to RNA polymerase I in scleroderma sera. J Clin Invest (1987) 1.99
La antigen recognizes and binds to the 3'-oligouridylate tail of a small RNA. Mol Cell Biol (1984) 1.97
Immunization of mice with purified U1 small nuclear ribonucleoprotein (RNP) induces a pattern of antibody specificities characteristic of the anti-Sm and anti-RNP autoimmune response of patients with lupus erythematosus, as measured by monoclonal antibodies. Proc Natl Acad Sci U S A (1986) 1.96
Association of the lupus antigen La with a subset of U6 snRNA molecules. Nucleic Acids Res (1985) 1.72
Splicing pathways of SV40 mRNAs in X. laevis oocytes differ in their requirements for snRNPs. Cell (1984) 1.69
Epitopes, structural domains, and asymmetry of amino acid residues in SS-B/La nuclear protein. J Immunol (1986) 1.63
Association between the 7 S RNA and the lupus La protein varies among cell types. J Biol Chem (1983) 1.51
A host protein (La) binds to a unique species of minus-sense leader RNA during replication of vesicular stomatitis virus. Proc Natl Acad Sci U S A (1983) 1.50
Identification of a La protein binding site in a RNA polymerase III transcript (4.5 I RNA). J Biol Chem (1983) 1.50
Monoclonal antibodies to the Sjögren's syndrome associated antigen SS-B (La). J Immunol Methods (1985) 1.46
Eukaryotic small ribonucleoproteins. Anti-La human autoantibodies react with U1 RNA-protein complexes. J Biol Chem (1984) 1.46
Reference sera for antinuclear antibodies. I. Antibodies to native DNA, Sm, nuclear RNP, and SS-B/La. Arthritis Rheum (1982) 1.33
Association of La and Ro antigens with intracellular structures in HEp-2 carcinoma cells. Proc Natl Acad Sci U S A (1986) 1.26
Detection of a cellular polypeptide associated with adenovirus-coded VA RNA using in vitro labeling of proteins cross-linked to RNA. Nucleic Acids Res (1982) 1.24
Splicing of Xenopus laevis ribosomal protein RNAs is inhibited in vivo by antisera to ribonucleoproteins containing U1 small nuclear RNA. J Mol Biol (1984) 1.23
The Ro/SSA autoantigen as an immunogen. Some anti-Ro/SSA antibody binds IgG. J Exp Med (1986) 1.02
Monoclonal IgM rheumatoid factors derived from arthritic MRL/Mp-lpr/lpr mice. J Exp Med (1983) 1.01
The small nuclear ribonucleoprotein SS-B/La binds RNA with a conserved protease-resistant domain of 28 kilodaltons. Mol Cell Biol (1987) 0.99
Immunologic and structural studies of the lupus/Sjögren's syndrome autoantigen, La/SSB, with a monoclonal antibody. J Clin Invest (1985) 0.86
A simple procedure for the isolation of IgG anti-nuclear antibodies from human serum. Clin Biochem (1974) 0.79
The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum (1982) 67.54
Antibodies reacting with ribosomal ribonucleoprotein in connective tissue diseases. Arthritis Rheum (1979) 13.72
Mixed connective tissue disease--an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med (1972) 11.51
Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine. Adv Immunol (1982) 9.73
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus. J Clin Invest (1966) 8.64
Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus. J Immunol (1966) 7.40
Autoantibody to centromere (kinetochore) in scleroderma sera. Proc Natl Acad Sci U S A (1980) 7.33
Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid. Science (1968) 5.88
Identification of antibodies to nuclear acidic antigens by counterimmunoelectrophoresis. Arthritis Rheum (1976) 5.33
Profiles of antinuclear antibodies in systemic rheumatic diseases. Ann Intern Med (1975) 5.00
Antibodies to cellular antigens in Sjögren's syndrome. J Clin Invest (1975) 4.62
Autoantibody to a nuclear antigen in proliferating cells. J Immunol (1978) 4.36
Differentiation and characterization of autoantibodies and their antigens in Sjögren's syndrome. Arthritis Rheum (1976) 4.02
Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin. J Exp Med (1991) 4.02
Diversity of antinuclear antibodies in progressive systemic sclerosis. Anti-centromere antibody and its relationship to CREST syndrome. Arthritis Rheum (1980) 3.87
Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI, 8.5) rich in NG,NG-dimethylarginine. J Biol Chem (1985) 3.60
Presence of anti-Sm reactivity in autoimmune mouse strains. J Exp Med (1978) 3.58
Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies. Exp Cell Res (1991) 3.44
Monoclonal autoantibody from a (New Zealand black x New Zealand white)F1 mouse and some human scleroderma sera target an Mr 34,000 nucleolar protein of the U3 RNP particle. Arthritis Rheum (1987) 3.09
Identification of a nuclear protein (Scl-70) as a unique target of human antinuclear antibodies in scleroderma. J Biol Chem (1979) 2.99
A 52-kD protein is a novel component of the SS-A/Ro antigenic particle. J Exp Med (1988) 2.98
A nuclear antigen associated with cell proliferation and blast transformation. J Exp Med (1981) 2.82
Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle. Exp Cell Res (1986) 2.74
Relationship of nuclear staining patterns with precipitating antibodies in systemic lupus erythematosus. J Lab Clin Med (1967) 2.71
Autoantibodies in the diagnosis of systemic rheumatic diseases. Semin Arthritis Rheum (1995) 2.67
Lymphocytes transformed by Epstein-Barr virus. Induction of nuclear antigen reactive with antibody in rheumatoid arthritis. J Exp Med (1978) 2.52
Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms in hypertensive patients treated with hydralazine. J Lab Clin Med (1970) 2.41
A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. J Exp Med (1999) 2.36
Association of antinuclear and antinucleolar antibodies in progressive systemic sclerosis. Clin Exp Immunol (1982) 2.29
Antinucleolar antibodies in human sera. J Immunol (1973) 2.28
Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. J Clin Invest (1991) 2.28
Association between the nucleolus and the coiled body. J Struct Biol (1991) 2.18
Monoclonal antibodies to a nuclear protein (PCNA/cyclin) associated with DNA replication. Exp Cell Res (1987) 2.13
Immunocytochemical analysis of the coiled body in the cell cycle and during cell proliferation. Proc Natl Acad Sci U S A (1993) 2.13
Evidence for a subset of rheumatoid factors that cross-react with DNA-histone and have a distinct cross-idiotype. J Exp Med (1980) 2.10
An immunofluorescent study of the skin lesions in systemic lupus erythematosus. Arthritis Rheum (1966) 2.07
Monoclonal antibodies to proliferating cell nuclear antigen (PCNA)/cyclin as probes for proliferating cells by immunofluorescence microscopy and flow cytometry. J Immunol Methods (1988) 2.07
Autoantibody to RNA polymerase I in scleroderma sera. J Clin Invest (1987) 1.99
An immunologic precipitin system between soluble nucleoprotein and serum antibody in systemic lupus erythematosus. J Clin Invest (1967) 1.99
Detection of a nucleolar 7-2 ribonucleoprotein and a cytoplasmic 8-2 ribonucleoprotein with autoantibodies from patients with scleroderma. J Biol Chem (1983) 1.98
Distribution of kinetochore (centromere) antigen in mammalian cell nuclei. J Cell Biol (1981) 1.97
Serum antibody in rheumatoid arthritis reactive with a cell-associated antigen. Demonstration by precipitation and immunofluorescence. Arthritis Rheum (1976) 1.92
Isolation and characterization of nuclear ribonucleoprotein complexes using human anti-nuclear ribonucleoprotein antibodies. J Biol Chem (1979) 1.92
Immunolocalization of 7-2-ribonucleoprotein in the granular component of the nucleolus. Exp Cell Res (1988) 1.87
Antibodies to histones in drug-induced and idiopathic lupus erythematosus. J Clin Invest (1978) 1.86
Immunohistochemical detection of proliferating cell nuclear antigen in solid human malignancies. Arch Pathol Lab Med (1987) 1.84
Characterization of proliferating cell nuclear antigen recognized by autoantibodies in lupus sera. J Exp Med (1984) 1.79
Autoimmune responses to mRNA binding proteins p62 and Koc in diverse malignancies. Clin Immunol (2001) 1.78
Oral aspirin challenges in asthmatic patients: a study of plasma histamine. Clin Allergy (1976) 1.74
Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding. Nucleic Acids Res (1989) 1.72
Novel nuclear autoantigen with splicing factor motifs identified with antibody from hepatocellular carcinoma. J Clin Invest (1993) 1.66
Epitopes, structural domains, and asymmetry of amino acid residues in SS-B/La nuclear protein. J Immunol (1986) 1.63
Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor. J Exp Med (1991) 1.63
Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1. J Clin Invest (1989) 1.61
Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen. J Clin Invest (1989) 1.59
Identification of ribosomal protein autoantigens. J Immunol (1985) 1.57
Correlates between autoantibodies to nucleolar antigens and clinical features in patients with systemic sclerosis (scleroderma). Arthritis Rheum (1988) 1.54
Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin and Ki-67 antigen: a new view of the cell cycle. Exp Cell Res (1990) 1.53
High frequency of autoantibodies to insoluble cellular antigens in patients with chronic fatigue syndrome. Arthritis Rheum (1997) 1.53
Monoclonal anti-histone autoantibodies derived from murine models of lupus. J Immunol (1984) 1.52
Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis. J Exp Med (1996) 1.52
IgG subclasses of autoantibodies in systemic lupus erythematosus, Sjogren's syndrome, and drug-induced autoimmunity. J Immunol (1986) 1.50
Identification of Ki (Ku, p70/p80) autoantigens and analysis of anti-Ki autoantibody reactivity. J Immunol (1986) 1.49
Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis. Am J Pathol (2001) 1.49
Ultraviolet light alteration of cellular deoxyribonucleic acid in vivo. Proc Natl Acad Sci U S A (1969) 1.48
Autoantibodies and the spectrum of Sjögren's syndrome. Ann Intern Med (1979) 1.44
Studies on antibodies to histones by immunofluorescence. Scand J Immunol (1976) 1.43
Distinct cleavage products of nuclear proteins in apoptosis and necrosis revealed by autoantibody probes. Cell Death Differ (1998) 1.43
Multiple autoantigen binding capabilities of mouse monoclonal antibodies selected for rheumatoid factor activity. J Exp Med (1984) 1.43
Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus. J. Immunol. 1966. 96: 464-471. J Immunol (2006) 1.42
CREB-binding protein (CBP)/p300 and RNA polymerase II colocalize in transcriptionally active domains in the nucleus. J Cell Biol (2000) 1.41
Coiled bodies in the nucleolus of breast cancer cells. J Cell Sci (1994) 1.41
Microhemagglutination test for detection of antibodies to nuclear Sm and ribonucleoprotein antigens in systemic lupus erythematosus and related diseases. Am J Clin Pathol (1978) 1.40
In vitro posttranslational modification of lamin B cloned from a human T-cell line. Mol Cell Biol (1990) 1.40
Clinical profiles of bronchial asthma. JAMA (1973) 1.39
Increasing titers and changing specificities of antinuclear antibodies in patients with chronic liver disease who develop hepatocellular carcinoma. Cancer (1993) 1.37
Autoantibodies to DFS 70 kd/transcription coactivator p75 in atopic dermatitis and other conditions. J Allergy Clin Immunol (2000) 1.36
An improved ELISA for anti-native DNA by elimination of interference by anti-histone antibodies. J Immunol Methods (1983) 1.36
Acquired congenital heart block. Pattern of maternal antibody response to biochemically defined antigens of the SSA/Ro-SSB/La system in neonatal lupus. J Clin Invest (1989) 1.36
Rheumatic disease sera reactive with capillaries in the mouse kidney. Arthritis Rheum (1972) 1.35
The clinical significance of antinuclear antibodies. Postgrad Med (1973) 1.33
Reference sera for antinuclear antibodies. I. Antibodies to native DNA, Sm, nuclear RNP, and SS-B/La. Arthritis Rheum (1982) 1.33
Seroepidemiological study of relationships between Epstein-Barr virus and rheumatoid arthritis. J Clin Invest (1981) 1.32
Recent progress in the study of autoantibodies to nuclear antigens. Hum Pathol (1978) 1.32
Antibodies to a nuclear/nucleolar antigen in patients with polymyositis overlap syndromes. J Clin Immunol (1984) 1.30
The importance of tissue substrate in the SS-A/Ro antigen-antibody system. Arthritis Rheum (1984) 1.30
The natural history of interstitial cystitis: a survey of 374 patients. J Urol (1993) 1.29
Comparative study of antibodies to native and denatured DNA. J Immunol (1970) 1.29
Dissociation of immune responses to the SS-A (Ro) 52-kd and 60-kd polypeptides in systemic lupus erythematosus and Sjögren's syndrome. Arthritis Rheum (1990) 1.28
Extraction and partial purification of the histamine-sensitizing factor of Bordetella pertussis. J Immunol (1974) 1.28
An immunological study of the fates of nuclear and nucleolar macromoleculus during the cell cycle. J Mol Biol (1972) 1.27
Experimental skin lesions in mice resembling systemic lupus erythematosus. Arthritis Rheum (1973) 1.27
Microvascular abnormalities as possible predictors of disease subsets in Raynaud phenomenon and early connective tissue disease. Clin Exp Rheumatol (1985) 1.25
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists. Am J Respir Cell Mol Biol (1998) 1.25
Specificities of antibodies to native DNA. Scand J Rheumatol Suppl (1975) 1.24
Effective separation of the 52 kDa SSA/Ro polypeptide from the 48 kDa SSB/La polypeptide by altering conditions of polyacrylamide gel electrophoresis. J Immunol Methods (1990) 1.23
Characterization of a phosphoprotein associated with the SS-B/La nuclear antigen in adenovirus-infected and uninfected KB cells. Mol Cell Biol (1983) 1.23