PubRank

Lawrence S B Goldstein

Author PubWeight™ 94.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Somatic coding mutations in human induced pluripotent stem cells. Nature 2011 9.50
2 Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science 2005 5.49
3 Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature 2012 5.47
4 Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci U S A 2003 4.47
5 A standardized kinesin nomenclature. J Cell Biol 2004 4.43
6 Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron 2003 4.04
7 Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron 2006 3.51
8 The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev 2010 3.37
9 Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS One 2011 2.74
10 JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev Cell 2003 2.45
11 Sunday Driver links axonal transport to damage signaling. J Cell Biol 2005 2.29
12 Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol 2003 2.02
13 Axonal transport and Alzheimer's disease. Annu Rev Biochem 2006 1.98
14 Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc Natl Acad Sci U S A 2008 1.84
15 Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem 2009 1.84
16 Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. Hum Mol Genet 2012 1.80
17 Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell 2007 1.67
18 A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. Cell Stem Cell 2013 1.59
19 Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proc Natl Acad Sci U S A 2011 1.52
20 Microtubule-dependent transport in neurons: steps towards an understanding of regulation, function and dysfunction. Curr Opin Cell Biol 2004 1.51
21 Principles of cargo attachment to cytoplasmic motor proteins. Curr Opin Cell Biol 2002 1.51
22 The genetics of axonal transport and axonal transport disorders. PLoS Genet 2006 1.49
23 Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre. Invest Ophthalmol Vis Sci 2006 1.38
24 Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell 2011 1.38
25 Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell 2010 1.32
26 Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Arch Neurol 2005 1.28
27 Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin. J Neurosci 2008 1.26
28 ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A 2012 1.25
29 Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease. J Neurobiol 2004 1.20
30 Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects. J Neurosci 2009 1.16
31 Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds. Tissue Eng Part A 2011 1.10
32 Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Hum Mol Genet 2008 1.06
33 Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Hum Mol Genet 2010 1.00
34 Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell 2012 1.00
35 The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells. Cell Rep 2013 1.00
36 Examination of potential mechanisms of amyloid-induced defects in neuronal transport. Neurobiol Dis 2009 0.98
37 Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein. Traffic 2013 0.94
38 Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration. Annu Rev Biophys 2014 0.90
39 Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles. Proc Natl Acad Sci U S A 2012 0.90
40 Alzheimer's disease in a dish: promises and challenges of human stem cell models. Hum Mol Genet 2012 0.89
41 Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo. Hum Mol Genet 2013 0.89
42 A genetic screen for suppressors and enhancers of the Drosophila cdk1-cyclin B identifies maternal factors that regulate microtubule and microfilament stability. Genetics 2002 0.89
43 Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects. Hum Mol Genet 2012 0.89
44 Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Exp Eye Res 2005 0.86
45 The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS One 2013 0.85
46 A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. Mol Biol Cell 2011 0.80
47 Linking molecular motors to Alzheimer's disease. J Physiol Paris 2006 0.79
48 Using human-induced pluripotent stem cells to model monogenic metabolic disorders of the liver. Semin Liver Dis 2013 0.78
49 Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function. J Cell Sci 2014 0.78
50 UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci 2014 0.77
51 Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS One 2012 0.76
52 Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem 2013 0.75