Published in Intensive Care Med on February 13, 2014
Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine. Intensive Care Med (2014) 1.43
Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) - short version. Ger Med Sci (2015) 0.94
Steroids for acute respiratory distress syndrome? Clin Chest Med (2014) 0.93
Neurological prognostication after cardiac arrest. Curr Opin Crit Care (2015) 0.78
Optimizing sedation in patients with acute brain injury. Crit Care (2016) 0.76
Validation of the Chinese version of the FOUR score in the assessment of neurosurgical patients with different level of consciousness. BMC Neurol (2015) 0.75
The ten wishes and hopes of the deputy editors of Intensive Care Medicine. Intensive Care Med (2016) 0.75
Pupillary abnormalities in non-selected critically ill patients: an observational study. J Thorac Dis (2017) 0.75
Risk factors for sepsis-associated encephalopathy. Intensive Care Med (2017) 0.75
Spontaneous intracranial haemorrhage in critically ill patients with malignancies. Support Care Cancer (2016) 0.75
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature (2010) 6.48
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab (2007) 4.51
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care (2009) 3.69
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science (2012) 3.52
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Mol Cell (2011) 3.33
Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury. Crit Care Med (2012) 3.32
Leptin therapy in insulin-deficient type I diabetes. Proc Natl Acad Sci U S A (2010) 3.23
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss. Sci Transl Med (2011) 3.20
Usefulness of transcranial echography in patients with decompressive craniectomy: a comparison with computed tomography scan. Crit Care Med (2012) 3.10
Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care (2011) 2.81
Continuous electroencephalographic monitoring in critically ill patients: indications, limitations, and strategies. Crit Care Med (2013) 2.79
Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine. Resuscitation (2014) 2.76
Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes (2009) 2.68
Inhalation versus endovenous sedation in subarachnoid hemorrhage patients: effects on regional cerebral blood flow. Crit Care Med (2012) 2.68
Cerebral blood flow threshold of ischemic penumbra and infarct core in acute ischemic stroke: a systematic review. Stroke (2006) 2.64
Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS Genet (2008) 2.63
European Resuscitation Council Guidelines for Resuscitation 2010 Section 2. Adult basic life support and use of automated external defibrillators. Resuscitation (2010) 2.62
Specialist neurocritical care and outcome from head injury. Intensive Care Med (2002) 2.57
Changing patterns in the epidemiology of traumatic brain injury. Nat Rev Neurol (2013) 2.55
Year in review in Intensive Care Medicine 2011: III. ARDS and ECMO, weaning, mechanical ventilation, noninvasive ventilation, pediatrics and miscellanea. Intensive Care Med (2012) 2.52
The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. Intensive Care Med (2003) 2.47
Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings. Crit Care Med (2008) 2.42
Dissecting the in vivo metabolic potential of two human gut acetogens. J Biol Chem (2010) 2.42
Nitric oxide represses the Arabidopsis floral transition. Science (2004) 2.41
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet (2010) 2.34
Hyperventilation following head injury: effect on ischemic burden and cerebral oxidative metabolism. Crit Care Med (2007) 2.32
Presence and severity of intensive care unit-acquired paresis at time of awakening are associated with increased intensive care unit and hospital mortality. Crit Care Med (2009) 2.31
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J Biol Chem (2009) 2.28
Prospective evaluation of pain and analgesic use following major elective intracranial surgery. J Neurosurg (2007) 2.26
Outcome following evacuation of acute subdural haematomas: a comparison of craniotomy with decompressive craniectomy. Acta Neurochir (Wien) (2012) 2.22
High heritability of metabolomic profiles in families burdened with premature cardiovascular disease. Mol Syst Biol (2009) 2.21
Patient-specific thresholds of intracranial pressure in severe traumatic brain injury. J Neurosurg (2014) 2.20
Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006. Intensive Care Med (2007) 2.18
Lactate uptake by the injured human brain: evidence from an arteriovenous gradient and cerebral microdialysis study. J Neurotrauma (2013) 2.18
Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. Cell Metab (2012) 2.11
The effect of red blood cell transfusion on cerebral oxygenation and metabolism after severe traumatic brain injury. Crit Care Med (2009) 2.10
Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury. Crit Care Med (2002) 2.10
Acute lung injury in critical neurological illness. Crit Care Med (2012) 2.09
Medical research in emergency research in the European Union member states: tensions between theory and practice. Intensive Care Med (2014) 2.05
Do vegetative patients retain aspects of language comprehension? Evidence from fMRI. Brain (2007) 2.03
A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion. J Biol Chem (2006) 2.03
Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion. Circulation (2009) 2.01
Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis. Cell Metab (2010) 2.00
Interscalene brachial plexus block: can the risk of entering the spinal canal be reduced? A study of needle angles in volunteers undergoing magnetic resonance imaging. Anesthesiology (2006) 1.96
Paroxysmal Sympathetic Hyperactivity in Pediatric Rehabilitation: Clinical Factors and Acute Pharmacological Management. J Head Trauma Rehabil (2015) 1.96
Randomized, controlled trial on the effect of a 20% mannitol solution and a 7.5% saline/6% dextran solution on increased intracranial pressure after brain injury. Crit Care Med (2005) 1.94
Diagnostic importance of pulmonary interleukin-1beta and interleukin-8 in ventilator-associated pneumonia. Thorax (2009) 1.87
Effect of hyperventilation on cerebral blood flow in traumatic head injury: clinical relevance and monitoring correlates. Crit Care Med (2002) 1.79
Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease. Proc Natl Acad Sci U S A (2009) 1.77
A multiparameter panel method for outcome prediction following aneurysmal subarachnoid hemorrhage. Intensive Care Med (2009) 1.75
Formal characterization and extension of the linearized diffusion tensor model. Hum Brain Mapp (2005) 1.75
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks. Cell Metab (2013) 1.70
Use of T2-weighted magnetic resonance imaging of the optic nerve sheath to detect raised intracranial pressure. Crit Care (2008) 1.69
Experience of diffusion tensor imaging and 1H spectroscopy for outcome prediction in severe traumatic brain injury: Preliminary results. Crit Care Med (2009) 1.69
Effect of cerebral perfusion pressure augmentation on regional oxygenation and metabolism after head injury. Crit Care Med (2005) 1.68
A review of paroxysmal sympathetic hyperactivity after acquired brain injury. Ann Neurol (2010) 1.68
Traumatic subarachnoid hemorrhage on the computerized tomography scan obtained at admission: a multicenter assessment of the accuracy of diagnosis and the potential impact on patient outcome. J Neurosurg (2003) 1.67
The cytokine response to human traumatic brain injury: temporal profiles and evidence for cerebral parenchymal production. J Cereb Blood Flow Metab (2010) 1.67
Efficacy of intravenous patient-controlled analgesia after supratentorial intracranial surgery: a prospective randomized controlled trial. Clinical article. J Neurosurg (2009) 1.64
Prognosis value of plasma S100B protein levels after subarachnoid aneurysmal hemorrhage. Anesthesiology (2006) 1.64
Comparison between SAPS II and SAPS 3 in predicting hospital mortality in a cohort of 103 Italian ICUs. Is new always better? Intensive Care Med (2012) 1.62
Aetiological differences in neuroanatomy of the vegetative state: insights from diffusion tensor imaging and functional implications. J Neurol Neurosurg Psychiatry (2010) 1.62
S100B as an additional prognostic marker in subarachnoid aneurysmal hemorrhage. Crit Care Med (2008) 1.61
Topographic distribution of tidal ventilation in acute respiratory distress syndrome: effects of positive end-expiratory pressure and pressure support. Crit Care Med (2013) 1.60
Functional recovery after moderate/severe traumatic brain injury: a role for cognitive reserve? Neurology (2014) 1.60
Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease. Am Heart J (2012) 1.59
Diagnostic accuracy of passive leg raising for prediction of fluid responsiveness in adults: systematic review and meta-analysis of clinical studies. Intensive Care Med (2010) 1.58
Dissociating speech perception and comprehension at reduced levels of awareness. Proc Natl Acad Sci U S A (2007) 1.56
Are optimal cerebral perfusion pressure and cerebrovascular autoregulation related to long-term outcome in patients with aneurysmal subarachnoid hemorrhage? J Neurosurg Anesthesiol (2012) 1.55
Acute respiratory distress syndrome: lessons from computed tomography of the whole lung. Crit Care Med (2003) 1.54
Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients. Brain (2011) 1.53
Acquired Muscle Weakness in the Surgical Intensive Care Unit: Nosology, Epidemiology, Diagnosis, and Prevention. Anesthesiology (2016) 1.53
Continuous low dose diclofenac sodium infusion to control fever in neurosurgical critical care. Neurocrit Care (2007) 1.52
Significance of triphasic waves in patients with acute encephalopathy: a nine-year cohort study. Clin Neurophysiol (2013) 1.51
Cost-effective outcome for treating poor-grade subarachnoid hemorrhage. Stroke (2003) 1.51
Opposed effects of hypertonic saline on contusions and noncontused brain tissue in patients with severe traumatic brain injury. Crit Care Med (2006) 1.50
Hierarchical log linear analysis of admission blood parameters and clinical outcome following traumatic brain injury. Acta Neurochir (Wien) (2010) 1.49
Multifractal analysis of hemodynamic behavior: intraoperative instability and its pharmacological manipulation. Anesthesiology (2012) 1.47
Controversies in the management of aneurysmal subarachnoid hemorrhage. Crit Care Med (2006) 1.47
Levels of vancomycin in the cerebral interstitial fluid after severe head injury. Intensive Care Med (2006) 1.46
Atorvastatin decreases computed tomography and S100-assessed brain ischemia after subarachnoid aneurysmal hemorrhage: a comparative study. Crit Care Med (2012) 1.45
The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study. Brain (2009) 1.45
Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation. FASEB J (2008) 1.45
Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury. Intensive Care Med (2015) 1.44
Where has all the lorazepam gone? BMJ (2011) 1.44
The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain. OMICS (2009) 1.43
Comment on: 'Hypocapnia and the injured brain: more harm than benefit'. Crit Care Med (2010) 1.42
Cerebral blood flow thresholds for cerebral ischemia in traumatic brain injury. A systematic review. Crit Care Med (2008) 1.42
A quantitative computed tomography assessment of brain weight, volume, and specific gravity in severe head trauma. Intensive Care Med (2005) 1.41
Year in review in Intensive Care Medicine 2011. II. Cardiovascular, infections, pneumonia and sepsis, critical care organization and outcome, education, ultrasonography, metabolism and coagulation. Intensive Care Med (2012) 1.39
Sepsis-associated encephalopathy and its differential diagnosis. Crit Care Med (2009) 1.39
"Why can't I give you my organs after my heart has stopped beating?" An overview of the main clinical, organisational, ethical and legal issues concerning organ donation after circulatory death in Italy. Minerva Anestesiol (2015) 1.39
A role for the default mode network in the bases of disorders of consciousness. Ann Neurol (2012) 1.39
Changes in resting neural connectivity during propofol sedation. PLoS One (2010) 1.37
Inflammation in human brain injury: intracerebral concentrations of IL-1alpha, IL-1beta, and their endogenous inhibitor IL-1ra. J Neurotrauma (2007) 1.36
Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy. Diabetes Care (2013) 1.35
Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis. Chem Biol (2007) 1.35
New class of potent catalysts of O2.-dismutation. Mn(III) ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins. Dalton Trans (2004) 1.34