Published in Intensive Care Med on January 24, 2006
Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections. Clin Microbiol Rev (2010) 2.66
Pharmacokinetics of single-dose daptomycin in patients with suspected or confirmed neurological infections. Antimicrob Agents Chemother (2011) 0.96
Cerebral microdialysis in clinical studies of drugs: pharmacokinetic applications. J Pharmacokinet Pharmacodyn (2013) 0.83
Microdialysis study of cefotaxime cerebral distribution in patients with acute brain injury. Antimicrob Agents Chemother (2013) 0.82
Comment on "Levels of vancomycin in the cerebral interstitial fluid after severe head injury" by Caricato et al. Intensive Care Med (2006) 0.75
Intrathecal and intraventricular antibiotics for postoperative Gram-negative meningitis and ventriculitis. Surg Neurol Int (2017) 0.75
Penetration of Vancomycin into the Cerebrospinal Fluid: A Systematic Review. Clin Pharmacokinet (2017) 0.75
Albumin replacement in patients with severe sepsis or septic shock. N Engl J Med (2014) 7.07
Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial. JAMA (2009) 6.55
A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality. Intensive Care Med (2014) 3.56
Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med (2014) 3.37
Prophylactic heparin in patients with severe sepsis treated with drotrecogin alfa (activated). Am J Respir Crit Care Med (2007) 3.34
Early vs late tracheotomy for prevention of pneumonia in mechanically ventilated adult ICU patients: a randomized controlled trial. JAMA (2010) 3.20
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med (2012) 3.18
Challenges in end-of-life care in the ICU. Statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003. Intensive Care Med (2004) 3.16
Usefulness of transcranial echography in patients with decompressive craniectomy: a comparison with computed tomography scan. Crit Care Med (2012) 3.10
Challenges in end-of-life care in the ICU: statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003: executive summary. Crit Care Med (2004) 2.95
Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine. Resuscitation (2014) 2.76
In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival. Intensive Care Med (2006) 2.72
European Resuscitation Council Guidelines for Resuscitation 2010 Section 2. Adult basic life support and use of automated external defibrillators. Resuscitation (2010) 2.62
Evaluation of patient skin breakdown and comfort with a new face mask for non-invasive ventilation: a multi-center study. Intensive Care Med (2002) 2.46
Adequacy of antimicrobial treatment and outcome of Staphylococcus aureus bacteremia in 9 Western European countries. Clin Infect Dis (2009) 2.39
The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks. Intensive Care Med (2011) 2.28
Nasal high-flow versus Venturi mask oxygen therapy after extubation. Effects on oxygenation, comfort, and clinical outcome. Am J Respir Crit Care Med (2014) 2.05
Euthanasia, therapeutic obstinacy or something else? An Italian case. Intensive Care Med (2005) 2.03
Noninvasive versus invasive ventilation for acute respiratory failure in patients with hematologic malignancies: a 5-year multicenter observational survey. Crit Care Med (2011) 1.96
Percutaneous translaryngeal versus surgical tracheostomy: A randomized trial with 1-yr double-blind follow-up. Crit Care Med (2005) 1.80
A meta-analysis of complications and mortality of extracorporeal membrane oxygenation. Crit Care Resusc (2013) 1.77
Systemic inflammatory response and progression to severe sepsis in critically ill infected patients. Am J Respir Crit Care Med (2004) 1.72
Noninvasive ventilation after early extubation in patients recovering from hypoxemic acute respiratory failure: a single-centre feasibility study. Intensive Care Med (2012) 1.63
Risk factors for acute kidney injury in critically ill patients receiving high intravenous doses of colistin methanesulfonate and/or other nephrotoxic antibiotics: a retrospective cohort study. Crit Care (2013) 1.60
Diagnostic accuracy of passive leg raising for prediction of fluid responsiveness in adults: systematic review and meta-analysis of clinical studies. Intensive Care Med (2010) 1.58
Noninvasive positive-pressure ventilation with different interfaces in patients with respiratory failure after abdominal surgery: a matched-control study. Respir Care (2007) 1.57
A multicenter, randomized trial of noninvasive ventilation with helium-oxygen mixture in exacerbations of chronic obstructive lung disease. Crit Care Med (2010) 1.56
Ventilator-associated pneumonia: current status and future recommendations. J Clin Monit Comput (2010) 1.54
A multicenter multinational study of abdominal candidiasis: epidemiology, outcomes and predictors of mortality. Intensive Care Med (2015) 1.54
Non-invasive ventilation delivered by conventional interfaces and helmet in the emergency department. Eur J Emerg Med (2003) 1.51
Online vs live methods for teaching difficult airway management to anesthesiology residents. Intensive Care Med (2005) 1.51
Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study. Intensive Care Med (2012) 1.47
In-hospital cardiac arrest: survival depends mainly on the effectiveness of the emergency response. Resuscitation (2004) 1.41
Perioperative management of antiplatelet therapy in patients with coronary stents undergoing cardiac and non-cardiac surgery: a consensus document from Italian cardiological, surgical and anaesthesiological societies. EuroIntervention (2014) 1.41
Antibiotic usage and risk of colonization and infection with antibiotic-resistant bacteria: a hospital population-based study. Antimicrob Agents Chemother (2009) 1.40
Noninvasive ventilation options in pediatric myasthenia gravis. Paediatr Anaesth (2005) 1.39
Immunonutrients in critically ill patients: an analysis of the most recent literature. Minerva Anestesiol (2015) 1.39
Early diagnosis of candidemia in intensive care unit patients with sepsis: a prospective comparison of (1→3)-β-D-glucan assay, Candida score, and colonization index. Crit Care (2011) 1.38
The epidemiology of acute respiratory failure in critically ill patients(*). Chest (2002) 1.29
High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria. Crit Care (2014) 1.25
Clinical outcomes of Pseudomonas aeruginosa pneumonia in intensive care unit patients. Intensive Care Med (2013) 1.24
Efficacy and safety of non-invasive ventilation in the treatment of acute cardiogenic pulmonary edema--a systematic review and meta-analysis. Crit Care (2006) 1.23
Hydroxyethyl starch for intravenous volume replacement: more harm than benefit. JAMA (2013) 1.22
Noninvasive vs invasive ventilation in COPD patients with severe acute respiratory failure deemed to require ventilatory assistance. Intensive Care Med (2004) 1.15
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit Care Med (2017) 1.15
Diagnosis of invasive aspergillosis by a commercial real-time PCR assay for Aspergillus DNA in bronchoalveolar lavage fluid samples from high-risk patients compared to a galactomannan enzyme immunoassay. J Clin Microbiol (2011) 1.15
Noninvasive versus conventional ventilation to treat hypercapnic encephalopathy in chronic obstructive pulmonary disease. Intensive Care Med (2007) 1.12
A prospective, blinded evaluation of indexes proposed to predict weaning from mechanical ventilation. Intensive Care Med (2004) 1.10
A low-dose remifentanil infusion is well tolerated for sedation in mechanically ventilated, critically-ill patients. Can J Anaesth (2002) 1.09
Levosimendan in Cardiac Surgery. N Engl J Med (2017) 1.06
Buffered crystalloids and acid-base state: still searching the optimal balance? Minerva Anestesiol (2015) 1.06
Effects of PEEP on the intracranial system of patients with head injury and subarachnoid hemorrhage: the role of respiratory system compliance. J Trauma (2005) 1.06
Noninvasive positive-pressure ventilation vs. conventional oxygen supplementation in hypoxemic patients undergoing diagnostic bronchoscopy. Chest (2002) 1.05
Accuracy of plethysmographic indices as predictors of fluid responsiveness in mechanically ventilated adults: a systematic review and meta-analysis. Intensive Care Med (2012) 1.03
Non-invasive ventilation in chronic obstructive pulmonary disease patients: helmet versus facial mask. Intensive Care Med (2006) 1.03
Neurological examination of critically ill patients: a pragmatic approach. Report of an ESICM expert panel. Intensive Care Med (2014) 1.02
The use of the Berlin definition for acute respiratory distress syndrome during infancy and early childhood: multicenter evaluation and expert consensus. Intensive Care Med (2013) 0.99
Nonthyroidal illness syndrome and prolonged mechanical ventilation in patients admitted to the ICU. Chest (2009) 0.97
European Resuscitation Council and European Society of Intensive Care Medicine 2015 guidelines for post-resuscitation care. Intensive Care Med (2015) 0.97
Noninvasive positive pressure ventilation delivered by helmet vs. standard face mask. Intensive Care Med (2003) 0.97
Unusual central venous catheter malposition into the left internal mammary vein: a case report. Intensive Care Med (2003) 0.97
Clinical experience of colistin-glycopeptide combination in critically ill patients infected with Gram-negative bacteria. Antimicrob Agents Chemother (2013) 0.97
Extended drotrecogin alfa (activated) treatment in patients with prolonged septic shock. Intensive Care Med (2009) 0.96
Incidence of and mortality due to sepsis, severe sepsis and septic shock in Italian Pediatric Intensive Care Units: a prospective national survey. Intensive Care Med (2008) 0.96
Noninvasive ventilation by helmet or face mask in immunocompromised patients: a case-control study. Chest (2004) 0.94
Why should we monitor (1-3)-β-D-glucan levels during invasive candidiasis? Just ask your ophthalmologist! J Clin Microbiol (2013) 0.92
Noninvasive mechanical ventilation as a palliative treatment of acute respiratory failure in patients with end-stage solid cancer. Palliat Med (2004) 0.89
How to manage aspergillosis in non-neutropenic intensive care unit patients. Crit Care (2014) 0.89
Is vasopressin superior to adrenaline or placebo in the management of cardiac arrest? A meta-analysis. Resuscitation (2003) 0.89
Noninvasive ventilation for the immunocompromised patient: always appropriate? Curr Opin Crit Care (2012) 0.89
Late-onset presentation of ornithine transcarbamylase deficiency in a young woman with hyperammonemic coma. Ann Emerg Med (2003) 0.88
Noninvasive pressure-support ventilation in immunocompromised children with ARDS: a feasibility study. Intensive Care Med (2009) 0.88
The role of mannose-binding lectin in severe sepsis and septic shock. Mediators Inflamm (2013) 0.87
Risk factors and outcome of Acinetobacter baumanii infection in severe trauma patients. Intensive Care Med (2009) 0.86
Year in review in intensive care medicine, 2004. III. Outcome, ICU organisation, scoring, quality of life, ethics, psychological problems and communication in the ICU, immunity and hemodynamics during sepsis, pediatric and neonatal critical care, experimental studies. Intensive Care Med (2005) 0.85
Comprehensive safety analysis of concomitant drotrecogin alfa (activated) and prophylactic heparin use in patients with severe sepsis. Intensive Care Med (2009) 0.85
Year in review in intensive care medicine, 2005. II. Infection and sepsis, ventilator-associated pneumonia, ethics, haematology and haemostasis, ICU organisation and scoring, brain injury. Intensive Care Med (2006) 0.84
Haemodynamic effects of mental stress during cardiac arrest simulation testing on advanced life support courses. Resuscitation (2005) 0.84
Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels. BMC Infect Dis (2014) 0.83
Linezolid plasma and intrapulmonary concentrations in critically ill obese patients with ventilator-associated pneumonia: intermittent vs continuous administration. Intensive Care Med (2014) 0.83
Sedation with sufentanil in patients receiving pressure support ventilation has no effects on respiration: a pilot study. Can J Anaesth (2004) 0.82
Failure of the afferent limb: a persistent problem in rapid response systems. Resuscitation (2011) 0.82
Physiologic evaluation of different levels of assistance during noninvasive ventilation delivered through a helmet. Chest (2005) 0.82
Are patients brain-dead after successful resuscitation from cardiac arrest suitable as organ donors? A systematic review. Resuscitation (2010) 0.82
Year in review in Intensive Care Medicine, 2006. II. Infections and sepsis, haemodynamics, elderly, invasive and noninvasive mechanical ventilation, weaning, ARDS. Intensive Care Med (2007) 0.82
Therapeutic hypothermia: is it effective for non-VF/VT cardiac arrest? Crit Care (2013) 0.82
Clinical and biological role of secretory phospholipase A2 in acute respiratory distress syndrome infants. Crit Care (2013) 0.81