Published in PLoS Med on February 25, 2014
Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase. J Am Coll Cardiol (2016) 1.49
Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change. PLoS Med (2014) 1.42
Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts. Circulation (2015) 1.25
A novel protein glycan biomarker and future cardiovascular disease events. J Am Heart Assoc (2014) 1.13
The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. Atherosclerosis (2014) 0.83
Circulating N-Linked Glycoprotein Acetyls and Longitudinal Mortality Risk. Circ Res (2016) 0.83
GlycA Is a Novel Biomarker of Inflammation and Subclinical Cardiovascular Disease in Psoriasis. Circ Res (2016) 0.83
Protein profiling reveals consequences of lifestyle choices on predicted biological aging. Sci Rep (2015) 0.82
GlycA, a Pro-Inflammatory Glycoprotein Biomarker, and Incident Cardiovascular Disease: Relationship with C-Reactive Protein and Renal Function. PLoS One (2015) 0.81
Circulating N-Linked Glycoprotein Side-Chain Biomarker, Rosuvastatin Therapy, and Incident Cardiovascular Disease: An Analysis From the JUPITER Trial. J Am Heart Assoc (2016) 0.81
Linking a population biobank with national health registries-the estonian experience. J Pers Med (2015) 0.81
Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence. Int J Epidemiol (2016) 0.81
A New, Discontinuous 2 Phases of Aging Model: Lessons from Drosophila melanogaster. PLoS One (2015) 0.79
An epidemiological perspective of personalized medicine: the Estonian experience. J Intern Med (2015) 0.78
Metabolic profiling of alcohol consumption in 9778 young adults. Int J Epidemiol (2016) 0.78
Discovery of Infection Associated Metabolic Markers in Human African Trypanosomiasis. PLoS Negl Trop Dis (2015) 0.78
Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects. Circ Cardiovasc Genet (2016) 0.77
Metabolic signatures of birthweight in 18 288 adolescents and adults. Int J Epidemiol (2016) 0.77
Metabolomics in epidemiology: from metabolite concentrations to integrative reaction networks. Int J Epidemiol (2016) 0.76
Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence. BMC Med (2016) 0.76
Early Antenatal Prediction of Gestational Diabetes in Obese Women: Development of Prediction Tools for Targeted Intervention. PLoS One (2016) 0.75
Association between inflammatory biomarkers and all-cause, cardiovascular and cancer-related mortality. CMAJ (2016) 0.75
Classification for Longevity Potential: The Use of Novel Biomarkers. Front Public Health (2016) 0.75
Nonspecific changes in clinical laboratory indicators in unselected terminally ill patients and a model to predict survival time based on a prospective observational study. J Transl Med (2014) 0.75
Serum glycoprotein-derived N- and O-linked glycans as cancer biomarkers. Am J Cancer Res (2016) 0.75
Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study. Am J Epidemiol (2016) 0.75
Identification of Novel N-Glycosylation Sites at Noncanonical Protein Consensus Motifs. J Proteome Res (2016) 0.75
Physiological predictors of long-term survival in juvenile Steller sea lions (Eumetopias jubatus). Conserv Physiol (2015) 0.75
Disease-specific classification using deconvoluted whole blood gene expression. Sci Rep (2016) 0.75
Inflammation, cardiovascular disease and cancer: moving toward predictive medicine. CMAJ (2016) 0.75
Phospholipid analysis in sera of horses with allergic dermatitis and in matched healthy controls. Lipids Health Dis (2016) 0.75
Glycosylation Signatures of Inflammation Identify Cardiovascular Risk: Some Glyc It Hot. Circ Res (2016) 0.75
Metabolic profiling-multitude of technologies with great research potential, but (when) will translation emerge? Int J Epidemiol (2016) 0.75
Differential Associations of Inflammatory Markers With Insulin Sensitivity and Secretion: The Prospective METSIM Study. J Clin Endocrinol Metab (2017) 0.75
Metabolic profiling of polycystic ovary syndrome reveals interactions with abdominal obesity. Int J Obes (Lond) (2017) 0.75
Genetic Support for a Causal Role of Insulin Resistance on Circulating Branched-Chain Amino Acids and Inflammation. Diabetes Care (2017) 0.75
Lipocalins Are Required for Apical Extracellular Matrix Organization and Remodeling in Caenorhabiditis elegans. Genetics (2017) 0.75
Low level activity thresholds for changes in NMR biomarkers and genes in high risk subjects for Type 2 Diabetes. Sci Rep (2017) 0.75
General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation (2008) 26.42
Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med (2006) 15.60
Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers. Stat Med (2010) 14.49
Metabolite profiles and the risk of developing diabetes. Nat Med (2011) 12.22
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA (2007) 11.98
Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med (2011) 10.33
Thirty-five-year trends in cardiovascular risk factors in Finland. Int J Epidemiol (2009) 5.37
Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat Genet (2012) 4.08
Choice of time-scale in Cox's model analysis of epidemiologic cohort data: a simulation study. Stat Med (2004) 3.93
Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation. Circulation (2013) 3.80
How cancer metabolism is tuned for proliferation and vulnerable to disruption. Nature (2012) 3.77
Association between serum albumin and mortality from cardiovascular disease, cancer, and other causes. Lancet (1989) 3.51
The implications of human metabolic network topology for disease comorbidity. Proc Natl Acad Sci U S A (2008) 3.41
Association of serum albumin and mortality risk. J Clin Epidemiol (1997) 3.40
Alpha-1-acid glycoprotein. Biochim Biophys Acta (2000) 3.00
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Serum albumin level and physical disability as predictors of mortality in older persons. JAMA (1994) 2.66
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism. Analyst (2009) 2.49
Effects of cholesterol and inflammation-sensitive plasma proteins on incidence of myocardial infarction and stroke in men. Circulation (2002) 2.44
The human plasma lipidome. N Engl J Med (2011) 2.35
An integrated clinico-metabolomic model improves prediction of death in sepsis. Sci Transl Med (2013) 2.23
Fasting and nonfasting lipid levels: influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction. Circulation (2008) 2.19
Metabolic phenotyping in clinical and surgical environments. Nature (2012) 2.09
Long-term leisure-time physical activity and serum metabolome. Circulation (2012) 1.81
Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function. Circulation (2012) 1.64
Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu. Int J Epidemiol (2014) 1.54
Biomarkers of inflammation predict both vascular and non-vascular mortality in older men. Eur Heart J (2008) 1.22
Alpha-1-acid glycoprotein as an independent predictor for treatment effects and a prognostic factor of survival in patients with non-small cell lung cancer treated with docetaxel. Clin Cancer Res (2003) 1.18
Toward new biomarkers of cardiometabolic diseases. Cell Metab (2013) 1.02
Biomarkers of inflammation and malnutrition associated with early death in healthy elderly people. J Am Geriatr Soc (2008) 0.99
Plasma citrate levels as a potential biomarker for glaucoma. J Ocul Pharmacol Ther (2011) 0.79
Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project. Lancet (2013) 4.13
Distribution and medical impact of loss-of-function variants in the Finnish founder population. PLoS Genet (2014) 2.89
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nat Genet (2015) 2.84
A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32,669 individuals. Hypertension (2013) 1.60
Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change. PLoS Med (2014) 1.42
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nat Genet (2015) 1.39
Chromosome X-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation. PLoS Genet (2014) 1.09
High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms. PLoS Genet (2014) 0.98
Cell Specific eQTL Analysis without Sorting Cells. PLoS Genet (2015) 0.87
Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits. Diabetes (2014) 0.86
Age- and sex-specific causal effects of adiposity on cardiovascular risk factors. Diabetes (2015) 0.86
Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses. Sci Rep (2016) 0.81
ST2 may not be a useful predictor for incident cardiovascular events, heart failure and mortality. Heart (2014) 0.78
No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Sci Rep (2016) 0.76
Insomnia does not mediate or modify the association between MTNR1B risk variant rs10830963 and glucose levels. Diabetologia (2016) 0.75