Published in J Biol Chem on April 12, 2014
Protective effects of dietary avocado oil on impaired electron transport chain function and exacerbated oxidative stress in liver mitochondria from diabetic rats. J Bioenerg Biomembr (2015) 2.01
Glutathione and mitochondria. Front Pharmacol (2014) 1.08
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S-glutathionylation reactions in mitochondrial function and disease. Front Cell Dev Biol (2014) 0.86
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Mitochondrial Redox Signaling and Tumor Progression. Cancers (Basel) (2016) 0.81
Protein S-glutathionlyation links energy metabolism to redox signaling in mitochondria. Redox Biol (2015) 0.79
The Measurement of Reversible Redox Dependent Post-translational Modifications and Their Regulation of Mitochondrial and Skeletal Muscle Function. Front Physiol (2015) 0.78
Induction of mitochondrial reactive oxygen species production by GSH mediated S-glutathionylation of 2-oxoglutarate dehydrogenase. Redox Biol (2016) 0.77
Glutaredoxin 2a overexpression in macrophages promotes mitochondrial dysfunction but has little or no effect on atherogenesis in LDL-receptor null mice. Atherosclerosis (2015) 0.75
Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π. JCI Insight (2016) 0.75
Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies. Redox Biol (2017) 0.75
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Assessing mitochondrial dysfunction in cells. Biochem J (2011) 6.36
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med (2013) 3.10
Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress. Curr Opin Pharmacol (2007) 3.00
High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. PLoS One (2011) 2.82
Molecular mechanisms and clinical implications of reversible protein S-glutathionylation. Antioxid Redox Signal (2008) 2.67
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Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proc Natl Acad Sci U S A (2006) 2.51
Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology. Free Radic Biol Med (2007) 2.47
Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes. Proc Natl Acad Sci U S A (2002) 2.35
Reversible glutathionylation of complex I increases mitochondrial superoxide formation. J Biol Chem (2003) 2.28
Reversible glutathionylation regulates actin polymerization in A431 cells. J Biol Chem (2001) 2.26
The ratio of oxidative phosphorylation complexes I-V in bovine heart mitochondria and the composition of respiratory chain supercomplexes. J Biol Chem (2001) 2.15
Repeatable noninvasive measurement of mouse myocardial glucose uptake with 18F-FDG: evaluation of tracer kinetics in a type 1 diabetes model. J Nucl Med (2013) 2.10
Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE. J Biol Chem (2004) 1.99
Glutathionylation of mitochondrial proteins. Antioxid Redox Signal (2005) 1.79
Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2. J Biol Chem (2001) 1.77
Mitochondria in heart failure. Cardiovasc Res (2010) 1.75
Mitochondrial complex I deficiency increases protein acetylation and accelerates heart failure. Cell Metab (2013) 1.74
Mitochondrial complex II in the post-ischemic heart: oxidative injury and the role of protein S-glutathionylation. J Biol Chem (2007) 1.68
Characterization of human glutaredoxin 2 as iron-sulfur protein: a possible role as redox sensor. Proc Natl Acad Sci U S A (2005) 1.68
Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms. J Biol Chem (2001) 1.63
Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes. Biochim Biophys Acta (2012) 1.62
Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase. J Biol Chem (2003) 1.55
Physiological diversity of mitochondrial oxidative phosphorylation. Am J Physiol Cell Physiol (2006) 1.54
Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3. J Biol Chem (2011) 1.53
Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation. Antioxid Redox Signal (2009) 1.50
S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal (2011) 1.49
Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications. Antioxid Redox Signal (2011) 1.48
Tissue variation in the control of oxidative phosphorylation: implication for mitochondrial diseases. Biochem J (2000) 1.43
Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates. J Biol Chem (2010) 1.37
Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing oxidative damage. J Biol Chem (2008) 1.36
Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy. Circ Res (2011) 1.32
Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis. Free Radic Biol Med (2009) 1.30
Mitochondria in cardiac hypertrophy and heart failure. J Mol Cell Cardiol (2012) 1.29
Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions. Redox Biol (2013) 1.28
Regulation of mitochondrial NADP+-dependent isocitrate dehydrogenase activity by glutathionylation. J Biol Chem (2005) 1.26
Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid. Biochemistry (2007) 1.17
Glutathionylation of adenine nucleotide translocase induced by carbon monoxide prevents mitochondrial membrane permeabilization and apoptosis. J Biol Chem (2010) 1.15
Switching metabolic genes to build a better heart. Circulation (2002) 1.13
Kinetic and mechanistic characterization and versatile catalytic properties of mammalian glutaredoxin 2: implications for intracellular roles. Biochemistry (2008) 1.10
Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase). Potential role in redox signal transduction. J Biol Chem (2003) 1.10
Catalytic activity of NADH-ubiquinone oxidoreductase (complex I) in intact mitochondria. evidence for the slow active/inactive transition. J Biol Chem (2000) 1.10
What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria? Antioxid Redox Signal (2007) 1.10
How does iron-sulfur cluster coordination regulate the activity of human glutaredoxin 2? Antioxid Redox Signal (2007) 1.08
Oxidative stress inhibits vascular K(ATP) channels by S-glutathionylation. J Biol Chem (2010) 1.06
A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's disease. Antioxid Redox Signal (2009) 1.03
Mitochondrial dysfunction in heart failure. Heart Fail Rev (2013) 1.02
Crucial yet divergent roles of mitochondrial redox state in skeletal muscle vs. brown adipose tissue energetics. FASEB J (2011) 1.00
Attenuation of doxorubicin-induced cardiac injury by mitochondrial glutaredoxin 2. Biochim Biophys Acta (2008) 1.00
Glutaredoxin 2 prevents H(2)O(2)-induced cell apoptosis by protecting complex I activity in the mitochondria. Biochim Biophys Acta (2010) 0.97
The biological roles of glutaredoxins. Biochem J (2012) 0.96
Glutaredoxin 2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells. Free Radic Biol Med (2011) 0.95
Protein thiyl radical mediates S-glutathionylation of complex I. Free Radic Biol Med (2012) 0.94
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3. J Biol Chem (2013) 0.92
ND3, ND1 and 39kDa subunits are more exposed in the de-active form of bovine mitochondrial complex I. Biochim Biophys Acta (2014) 0.91
Redox regulation of mitochondrial ATP synthase. Trends Cardiovasc Med (2013) 0.90
Redox proteomics of thiol proteins in mouse heart during ischemia/reperfusion using ICAT reagents and mass spectrometry. Free Radic Biol Med (2013) 0.89
Vertebrate-specific glutaredoxin is essential for brain development. Proc Natl Acad Sci U S A (2011) 0.89
Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: implications for cardiac aging. Antioxid Redox Signal (2010) 0.89
Mitochondrial respiratory chain complexes as sources and targets of thiol-based redox-regulation. Biochim Biophys Acta (2014) 0.85
GSSG-mediated Complex I defect in isolated cardiac mitochondria. Int J Mol Med (2010) 0.81
Glutathione controls the redox state of the mitochondrial carnitine/acylcarnitine carrier Cys residues by glutathionylation. Biochim Biophys Acta (2013) 0.78